• Vascular Specialist International
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• 제34권4호
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• pp.94-102
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• 2018

Purpose: Aim of this study is to report real-life experience on the treatment of peripheral artery disease (PAD) with a specific drug-coated balloon (DCB), and to evaluate potential prognostic factors for outcomes. Materials and Methods: This is a retrospective study reporting outcomes in patients with PAD who were treated with the Lutonix DCB during a four-year period. Major outcomes included: all-cause mortality, amputation, clinical improvement, wound healing and target lesion revascularization (TLR). Mean follow-up was $24.2{\pm}2.3$ months. Results: Overall, 149 patients (mean age: $68.6{\pm}8.3$ years; 113 males) were treated, either for intermittent claudication (IC) (n=86) or critical limb ischemia (CLI) (n=63). More than half the target lesions (n=206 in total) were located in the superficial femoral artery and 18.0% were below-the-knee lesions. CLI patients presented more frequently with infrapopliteal (P=0.002) or multilevel disease (P=0.0004). Overall, all-cause mortality during follow-up was 10.7%, amputation-free survival was 81.2% and TLR-free survival was 96.6%. CLI patients showed higher all-cause mortality (P=0.007) and total amputation (P=0.0001) rates as well as lower clinical improvement (P=0.0002), compared to IC patients. Coronary artery disease (CAD), gangrene and infrapopliteal disease were found to be predictors for death whereas CLI and gangrene were found to be predictors for amputation, during follow-up. Conclusion: PAD treatment with Lutonix DCBs seems to be an efficient and safe endovascular strategy yielding promising results. However, CAD, gangrene, CLI and infrapopliteal lesions were found to be independent predictors for adverse outcomes. Larger series are needed to identify additional prognostic factors.

• 우울조울병
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• 제16권3호
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• pp.158-162
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• 2018

Objectives : The purpose of this study was to examine psychosocial factors related to burnout of social welfare officers working in Jeonnam Province. Methods : A total of 395 social welfare officers (male 99, female 296) working in 22 areas of Jeollanam-do province, were subjects of this study. We examined socio-demographic factors, using a self-reporting questionnaire. Subjects were asked to complete the Maslach Burnout Inventory-General Survey (MBI-GS), Center for Epidemiological Studies Depression Scale (CES-D), Perceived Stress Scale (PSS), and the Generalized Self-Efficacy Scale (GSS), to assess psychosocial factors affecting to burnout of social welfare officers. Results : Among 395 subjects, 221 (55.9%) reported recent experiences of burnout. There was no significant difference in age between two groups, divided by burnout. Sex (p<0.001), rank (p=0.003), working period (p=0.034), depression (p<0.001) revealed differences between the burnout group and control group. Scores of PSS (p<0.001) were higher, while the scores of GSS (p<0.001) were lower in the burnout group, than control group. Multivariate logistic regression analysis revealed that female (OR 2.840, 95%CI 1.466-5.504, p=0.002), depressive high-risk group (OR 6.824, 95%CI 2.893-16.096, p<0.001) PSS (OR 1.247, 95%CI 1.153-1.349, p<0.001) and GSS (OR 0.950, 95%CI 0.930-0.971, p<0.001), were significantly associated with burnout. Conclusion : We found that some factors, were associated with experienced burnout in social welfare officers. Depressive symptoms were the strongest associative factor, for burnout in public servants in charge of social welfare. Sex, stress and self-efficacy also correlated with burnout, and especially self-efficacy was a protecting factor.

• 대한비뇨기종양학회지
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• 제16권3호
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• pp.110-118
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• 2018

Purpose: The aim of this study is to confirm the detection rate of transperineal biopsy after multiparametric magnetic resonance imaging (mpMRI) and compared it to that of transrectal biopsy. We also examined the role of mpMRI and the rate of complications for each method. Materials and Methods: In a retrospective study, we analyzed 147 patients who underwent mpMRI before prostate biopsy because of elevated serum prostate-specific antigen and/or abnormal digital rectal examination findings at Korea University Hospital, Seoul, Korea from March 2017 to April 2018. Regions on the mpMRI that were suggestive of prostate cancer were categorized according to the Prostate Imaging-Reporting and Data System (PI-RADS v2). For transperineal biopsy, a 20-core saturation biopsy was performed by MRI-TRUS cognitive or fusion techniques and a 12-core biopsy was performed in transrectal biopsy. Results: Sixty-three and 84 patients were enrolled in transperineal group and transrectal group, respectively. The overall detection rate of prostate cancer in transperineal group was 27% higher than that in transrectal group. Classification according to PI-RADS score revealed a significant increase in detection rate in all patients, as the PI-RADS score increased. Frequency of complications using the Clavien-Dindo classifications revealed no significant differences in the total complications rate, but two patients in transrectal group received intensive care unit care due to urosepsis. Conclusions: Our results confirmed that transperineal biopsy is superior to transrectal biopsy for the detection of prostate cancer. From the complication point of view, this study confirmed that there were fewer severe complications in transperineal biopsy.

• 한국콘텐츠학회논문지
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• 제18권11호
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• pp.171-187
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• 2018

연구는 초 중학생의 주의력 결핍, 과잉행동/충동성, 인터넷 과다사용 등의 행동문제에 영향을 주는 생활양식 요인들을 알아보는데 목적이 있다. 초등학생 889명과 중학생 676명의 자기-보고 자료와 학생의 주의력 결핍과 과잉행동 및 충동성 증상에 대한 담임교사의 보고를 분석에 사용하였다. 생활양식은 가족과의 상호작용 기회, 수면시간, TV 시청시간, 게임시간, 아침식사 횟수, 가공식품 섭취 횟수, 과외 횟수 및 시간으로 측정하였다. 단계적 회귀분석 결과, 초등학생과 중학생 모두에서 게임시간, 가공식품 섭취 횟수가 많을수록, 가족과의 상호작용 기회가 적을수록 주의력 결핍 증상이 높았다. 초등학생의 경우 게임시간 TV 시간, 가공식품 섭취횟수가 많을수록, 보호자와 함께 하는 시간이 적을수록 과잉행동 및 충동성이 높았지만, 중학생의 경우 생활양식 변인들은 과잉행동 및 충동성에 대한 설명량이 낮았다. 초등학생과 중학생 모두에서 게임 시간이 많을수록, 보호자와 함께 하는 시간이 적을수록 인터넷 과다사용 증상이 높았다. 본 연구는 청소년의 행동문제에 대한 게임 및 TV 사용, 가공식품 섭취의 영향력을 고려하고, 가족과의 상호작용을 높이는 방향의 중재를 제안한다.

• 한국산학기술학회논문지
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• 제20권4호
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• pp.189-196
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• 2019

이 연구는 학부모와 유아교사의 아동학대에 대한 인식 차이를 분석하고자 G 지역 유아교육기관에 소속된 학부모와 유아교사를 연구대상으로 설문지 조사를 실시하였다. 아동학대(신체, 언어, 정서 및 사고, 방임, 예방대책, 개선방안)에 관한 항목으로 질문하여 얻어진 자료는 SPSS 21.0 프로그램을 이용해 빈도와 백분율, 평균과 표준편차를 계산하여 t검정과 ${\chi}^2$ 검정을 실시하였다. 이를 통해 얻은 연구결과는 첫째, 아동학대에 대한 인식차이는 학부모보다 유아교사가 더 높게 나타났다. 하위내용에 대한 인식은 학부모와 유아교사 모두 방임, 신체, 정서 및 사고, 언어 순이다. 둘째, 예방대책에 대해서는 인식 차이가 있는 것으로 나타났는데, 하위내용 중 아동학대 예방교육의 경험유무와 참여세미나 교육에 대해서는 학부모가 더 높게 인식하였고, 아동학대 예방교육의 인지도와 만족도, 아동보호 전문기관의 법적 역할과 기능에 대한 정보 인지도, 아동학대 신고 의무화 및 의무자의 인지도는 유아교사가 더 높게 인식하였다. 셋째, 아동학대 개선방안에 대해서도 인식 차이가 있는 것으로 나타났는데, 하위내용 중 아동학대 예방교육 실시와 자료 제공, 대중매체를 통한 아동학대 실태 및 대책 홍보, 대중매체를 활용한 아동학대 예방교육 확대, 아동학대 신고 의무자들의 의무교육에 대해서는 유아교사가 더 높게 인식하였다. 이러한 결과를 통해 학부모와 유아교사의 아동학대 예방에 대한 이해와 인식의 기초자료를 제공해 줄 수 있을 것으로 기대된다.

• 한국기후변화학회지
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• 제6권3호
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• pp.233-241
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• 2015

In 2014, the United Nations Framework Convention on Climate Change (UNFCCC) agreed to submit the Intended Nationality Determined Contributions (INDCs) at the conference of parties held in Lima, Peru. Then, the South Korean government submitted the INDCs including GHGs reduction target and reduction potential on July, 2015. The goal of this study is to predict GHGs emission and to analyze reduction potential in agricultural sector of Korea. Activity data to estimate GHGs emission was forecast by Korea Agricultural Simulation Model (KASMO) of Korea Rural Economic Institute and estimate methodology was taken by the IPCC and guideline for MRV (Measurement, Reporting and Verification) of national greenhouse gases statistics of Korea. The predicted GHGs emission of agricultural sectors from 2021 to 2030 tended to decrease due to decline in crop production and its gap was less after 2025. Increasing livestock numbers such as sheep, horses, swine, and ducks did not show signigicant impact the total GHGs emission. On a analysis of the reduction potential, GHGs emission was expected to reduce $253Gg\;CO_{2-eq}$. by 2030 with increase of mid-season water drainage area up to 95% of total rice cultivation area. The GHGs reduction potential with intermittent drainage technology applied to 10% of the tatal paddy field area, mid-drainage and no organic matter would be $92Gg\;CO_{2-eq}$. by 2030.

• Investigative and Clinical Urology
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• 제59권6호
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• pp.363-370
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• 2018

Purpose: The aim of this study is to describe the technique and to report early results of transperineal magnetic resonance imaging and ultrasonography (MRI-US) fusion biopsy. Materials and Methods: A total of 75 patients underwent MRI-US fusion transperineal biopsy. Targeted biopsy via MRI-US fusion imaging was carried out for cancer-suspicious lesions with additional systematic biopsy. Detection rates for overall and clinically significant prostate cancer (csPCa) were evaluated and compared between systematic and targeted biopsy. In addition, further investigation into the detection rate according to prostate imaging reporting and data system (PI-RADS) score was done. Results of repeat biopsies were also evaluated. Results: Overall cancer detection rate was 61.3% (46 patients) and the detection rate for csPCa was 42.7% (32 patients). Overall detection rates for systematic and targeted biopsy were 41.3% and 57.3% (p<0.05), respectively. Detection rates for csPCa were 26.7% and 41.3%, respectively (p<0.05). The cancer detection rates via MRI fusion target biopsy were 30.8% in PI-RADS 3, 62.1% in PI-RADS 4 and 89.4% in PI-RADS 5. Rates of csPCa missed by targeted biopsy and systematic biopsy were 0.0% and 25.0%, respectively. The cancer detection rate in repeat biopsies was 61.1% (11 among 18 patients) in which 55.5% of cancer suspected lesions were located in the anterior portion. Conclusions: Transperineal MRI-US fusion biopsy is useful for improving overall cancer detection rate and especially detection of csPCa. Transperineal MRI-US targeted biopsy show potential benefits to improve cancer detection rate in patients with high PIRADS score, tumor located at the anterior portion and in repeat biopsies.

• 고령자･치매작업치료학회지
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• 제12권2호
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• pp.67-74
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• 2018

목적 본 연구의 목적은 텍스트 마이닝이라는 빅데이터 분석 기법 중 하나를 활용하여 노인장기요양보험에서 작업치료의 역할을 정량적으로 분석하는 것이다. 연구방법 신문기사 분석을 위해 2007~208년까지 기간 설정 후 "노인장기요양보험+작업치료"를 주제어로 수집하였다. Textom이라는 웹 크롤링(Web Crawling)을 활용해 국내 검색엔진 네이버에서 <네이버뉴스>의 데이터베이스를 활용하였다. 수집결과 노인장기요양보험+작업치료 검색에서 510편의 뉴스 데이터의 기사제목과 원문을 수집한 후 연도별 기사 빈도, 핵심어분석을 시행하였다. 연구결과 연도별 기사 발행 빈도를 살펴보면 2015년과 2017년 발행한 기사 수가 70편(13.7%)으로 가장 많았고, 핵심어 분석 상위 10개의 용어는 '치매'(344)가 가장 많았으며, 작업과 핵심어의 관례를 알아보면, 치매, 치료, 병원, 건강, 서비스, 재활, 시설, 제도, 등급, 어르신, 전문, 급여, 공단, 국민이 관련이 있는 것으로 나타났다. 결론 본 연구에서는 텍스트 마이닝 기법을 통해 11년간의 노인장기요양보험의 언론 보도 동향을 토대로 관련 핵심 키워드에서 치매와 재활에 대해 사회적 요구와 작업치료사의 역할을 보다 객관적으로 확인하였다는 점에서 의의가 있다. 이 결과를 바탕으로 다음 연구에서는 연도에 따른 다양한 분석방법을 통해 연구방법론을 보완하여야 할 것이다.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1110-1118
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• 2018

Objective: To perform a meta-analysis to quantitatively assess functional magnetic resonance imaging (MRI) in the diagnosis of locally recurrent prostate cancer. Materials and Methods: A comprehensive search of the PubMed, Embase, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews was conducted from January 1, 1995 to December 31, 2016. Diagnostic accuracy was quantitatively pooled for all studies by using hierarchical logistic regression modeling, including bivariate modeling and hierarchical summary receiver operating characteristic (HSROC) curves (AUCs). The Z test was used to determine whether adding functional MRI to T2-weighted imaging (T2WI) results in significantly increased diagnostic sensitivity and specificity. Results: Meta-analysis of 13 studies involving 826 patients who underwent radical prostatectomy showed a pooled sensitivity and specificity of 91%, and the AUC was 0.96. Meta-analysis of 7 studies involving 329 patients who underwent radiotherapy showed a pooled sensitivity of 80% and specificity of 81%, and the AUC was 0.88. Meta-analysis of 11 studies reporting 1669 sextant biopsies from patients who underwent radiotherapy showed a pooled sensitivity of 54% and specificity of 91%, and the AUC was 0.85. Sensitivity after radiotherapy was significantly higher when diffusion-weighted MRI data were combined with T2WI than when only T2WI results were used. This was true when meta-analysis was performed on a per-patient basis (p = 0.027) or per sextant biopsy (p = 0.046). A similar result was found when $^1H$-magnetic resonance spectroscopy ($^1H$-MRS) data were combined with T2WI and sextant biopsy was the unit of analysis (p = 0.036). Conclusion: Functional MRI data may not strengthen the ability of T2WI to detect locally recurrent prostate cancer in patients who have undergone radical prostatectomy. By contrast, diffusion-weight MRI and $^1H$-MRS data may improve the sensitivity of T2WI for patients who have undergone radiotherapy.

• 과학교육연구지
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• 제42권3호
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• pp.308-321
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• 2018

이 연구는 과학탐구 상황에서 반회의주의적 태도를 조사하는 문항을 개발하는 것이 목적이다. 문헌 연구, 전문가 검토, 통계적 타당도 검증을 거쳐 문항을 개발하고, 성별, 계열별로 점수 차이를 확인하였다. 이 연구를 위하여 363명의 고등학생들이 참여하였다. 문항 타당도 확인을 위하여 라쉬 분석, 내적 일관성 신뢰도 확인 등을 수행하였고, 성별과 계열별 반회의주의적 태도의 점수 비교를 위하여 이원분산분석을 확인하였다. 연구 결과 과학탐구상황에서 반회의주의 태도를 측정할 수 있는 23개 리커트 형태의 자기보고형 검사도구를 개발하였다. 반회의주의적 태도 측정을 위하여 과학탐구 상황을 크게 '문제 인식과 가설 생성', '실험 설계', '관찰', '설명과 해석'으로 구분하여 각 구인별로 측정할 수 있는 다수의 문항을 개발하였다. 둘째, 과학탐구상황에서 반회의주의 태도 측정 문항의 타당도와 신뢰도를 엄격한 방법을 통해 확인하였다. 라쉬 분석을 통해 다차원 부분점수모델의 분석의 적합성을 확인하였으며, 라쉬 분석을 통해 문항 적합도를 확인한 결과 23개 문항 모두 적합으로 나타났다. 다양한 신뢰도 지수도 적합한 것으로 나타났다. 남학생과 여학생, 문과계열과 이과계열별로 구분하여 반회의주의적 태도를 비교한 결과 유의미한 차이를 나타낸 비교는 실험설계에서 계열별 차이를 제외하고 없는 것으로 확인되었다. 개발된 문항들을 활용하여 과학탐구 과정에서 반회의주의적 태도를 점검하고, 과학탐구 수업의 효과를 비교하는데 활용될 수 있을 것이다.