• Title/Summary/Keyword: renew

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Challenges of stem cell therapies in companion animal practice

  • Kang, Min-Hee;Park, Hee-Myung
    • Journal of Veterinary Science
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    • v.21 no.3
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    • pp.42.1-42.22
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    • 2020
  • Regenerative medicine using stem cells from various sources are emerging treatment modality in several refractory diseases in veterinary medicine. It is well-known that stem cells can differentiate into specific cell types, self-renew, and regenerate. In addition, the unique immunomodulatory effects of stem cells have made stem cell transplantation a promising option for treating a wide range of disease and injuries. Recently, the medical demands for companion animals have been rapidly increasing, and certain disease conditions require alternative treatment options. In this review, we focused on stem cell application research in companion animals including experimental models, case reports and clinical trials in dogs and cats. The clinical studies and therapeutic protocols were categorized, evaluated and summarized according to the organ systems involved. The results indicate that evidence for the effectiveness of cell-based treatment in specific diseases or organ systems is not yet conclusive. Nonetheless, stem cell therapy may be a realistic treatment option in the near future, therefore, considerable efforts are needed to find optimized cell sources, cell numbers and delivery methods in order to standardize treatment methods and evaluation processes.

Mary Shelley's The Last Man: Hospitability at the end of History (메리 셸리의 『최후의 인간』 -역사 끝에 선 환대)

  • Ryu, Son-Moo
    • Journal of English Language & Literature
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    • v.58 no.1
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    • pp.93-115
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    • 2012
  • The decades after the French Revolution witnessed the prolific production and consumption of apocalyptic literature, tinged with the optimistic vision of political progress and human perfectibility. However, the Romantic writers were cautious to embrace the idea of the end of history, even though it promised an aesthetic space relieved of historical determinants. Mary Shelley's The Last Man joined this line of Romantic literature which skeptically questions the millenarian desires of political apocalypse by representing apocalypse without millenium. Using the theme of apocalypse as a tool to investigate the place of human beings in the universe and to test diverse political reform ideas to their fullest potential, the novel diagnoses the ideas of representative political subject as the most problematic aspect of political structure. The notion of subjecthood presupposes a political decision as to who can be counted as subject and this decision, according to the novel, assumed a subject that is "active, free, conscious and willful sovereign," which Raymond embodies in his exemplary body. Against the sovereignty of Raymond is juxtaposed the subaltern subject such as Sybil. The resistance of Sybil to Apollo, another exemplary subject, is the subtext of the novel, which guides the way out of the grim future of humanity. While the plague exemplifies the universalizing ideal with its principle of sovereignty, Sybil and her descendent Lionel practice the unconditional hospitality so that they can renew the community in a way to embrace singularities of individuals.

New or Renew: Constructing Tomorrow with Kit of Parts

  • Ilkay Standard;Sena Kucukayan
    • International Journal of High-Rise Buildings
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    • v.13 no.1
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    • pp.97-102
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    • 2024
  • In this paper, we would like to share our ongoing research on global population and demographic shifts and the corresponding need for diverse responses. As population growth varies worldwide, the pressing issue is the current global housing shortage. The USA alone lacks 4 million homes, underlining the urgency for new construction and renewal of existing. Our focus is primarily on new building processes, which must also incorporate elements of renewal for future sustainability. Our research addresses several key questions: How will roles for construction professionals change? What should be the primary goal of the design process? What types of technologies are currently available, and which aspects of the process can be enhanced with AI? A significant part of our study is exploring sustainable building methods that reduce embodied carbon and increase speed of construction. Our goal is to extend the transition from smart homes to cities, analyzing the evolution towards smart communities and cities. A critical aspect of our research is the 'kit of parts concept, involving prefabrication and modular construction. This approach is essential for both rebuilding and new projects, potentially lowering costs in manufacturing and design for long term. Lastly, we present a detailed comparison of the construction industry with manufacturing.

A Study on Determination of the Matching Size of IKONOS Stereo Imagery (IKONOS 스테레오 영상의 매칭사이즈 결정연구)

  • Lee, Hyo-Seong;Ahn, Ki-Weon;Lee, Chang-No;Seo, Doo-Cheon
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2007.04a
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    • pp.201-205
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    • 2007
  • In the post-Cold War era, acquisition technique of high-resolution satellite imagery (HRSI) has begun to commercialize. IKONOS-2 satellite imaging data is supplied for the first time in the 21st century. Many researchers testified mapping possibility of the HRSI data instead of aerial photography. It is easy to renew and automate a topographical map because HRSI not only can be more taken widely and periodically than aerial photography, but also can be directly supplied as digital image. In this study matching size of IKONOS Geo-level stereo image is presented lot production of digital elevation model (DEM). We applied area based matching method using correlation coefficient of pixel brightness value between the two images. After matching line (where "matching line" implies straight line that is approximated to complex non-linear epipolar geometry) is established by exterior orientation parameters (EOPs) to minimize search area, the matching is tarried out based on this line. The experiment on matching size is performed according to land cover property, which is divided off into four areas (water, urban land, forest land and agricultural land). In each of the test areas, window size for the highest correlation coefficient is selected as propel size for matching. As the results of experiment, the proper size was selected as $123{\times}123$ pixels window, $13{\times}13$ pixels window, $129{\times}129$ pixels window and $81{\times}81$ pixels window in the water area, urban land, forest land and agricultural land, respectively. Of course, determination of the matching size by the correlation coefficient may be not absolute appraisal method. Optimum matching size using the geometric accuracy therefore, will be presented by the further work.

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Gastrointestinal Cancer Incidence in East Azerbaijan, Iran: Update on 5 Year Incidence and Trends

  • Somi, Mohammad Hossein;Golzari, Mehrad;Farhang, Sara;Naghashi, Shahnaz;Abdollahi, Leila
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3945-3949
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    • 2014
  • Background: A cancer registry program has been established in East Azerbaijan and this has emphasized the importance of cancers of gastrointestinal tract in this region. The aim of the present pathology-based cancer registry report is to renew epidemiologic aspects of gastrointestinal tract cancers and estimate recent trends. Materials and Methods: A survey team reviewed and collected all records of cancer cases from all referral and valid pathology laboratories of East Azerbaijan province during September 2007-2011. Crude rates, age-specific rates of cancer incidence and annual percent change were calculated. Results: The total newly diagnosed cancer cases (n=6,889)comprised 4,341 males (63.0%) and 2,540 females (36.9%). Gastric cancer was the most common GI tract cancer with an ASR (per $10^5$) of 23.1 for males and 7.69 for females. The ASRs for esophageal and colorectal cancers were 9.69 and 11.2 in males and 7.35 and 8.93 in females. Trend analysis showed a significant decline for esophageal cancer and increasing incidence for colorectal cancer in females. Conclusions: The prevalence of gastric cancer is high in East Azerbaijan province of Iran. This pathology based cancer registry showed an ascending trend for colorectal cancer and decreasing trend for esophageal cancer in females during 2007-2011.

Environmental Impact Assessment within Regional and Municipal Planning (지역 및 도시계획에서의 환경영향평가)

  • Socher, Wolfgang
    • Journal of Environmental Impact Assessment
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    • v.4 no.3
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    • pp.27-29
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    • 1995
  • Within regional and municipal planning we are using several levels or types of EIA in the city of Dresden. Some of these types, practical aspects and some experiences of our work will be presented in this contribution. Firstly I may introduce you to some general conditions for your better understanding of our principles of work. Surely you know about. the destruction of the political and economical structures in Eastern Germany since 1989. Until today our not quite simple task is to build up new ones. At the same time people were in great expectation of freedom and high standard of living as soon as possible. Economical difficulties increased in association with the breakdown of the market in Eastern Europe. How to rebuild industrial estatements and how to renew the traffic systems? We had to find answers to all these complex question. Should we only repair the former damages or could we reach a really environmental sound production for the future? The demand for a rapid economic growth is an incredible challenge for the application of new environmental ideas. I am truly not sure whether you know the city of Dresden or not. So I would like to give you a short introduction. Dresden is situated in a valley shaped by the river Elbe. There live about 500,000 people. Dresden has a great reputation for arts and sciences. Its also well know as a town of high technology industries such as electronics and optics. We restored the power plant and therefore we don't need any atomic power plants actually we haven't got one. Since 1990 there were founded many official agencies in Dresden because it is the capatal of Saxony. Considering nature and environment we there is a large forest area called "Dresdner Heide". The river Elbe and the meadows are situated on both sides of the river. There are a lot of green and free places in the city area too. Furtheron there is something unusual for a large city: about 50% of the drinking water resources mostly take place within the city itself. The origin is the ground water as well as water from the river Elbe after filtration of course.

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Enhancement of Transgene Expression by HDAC Inhibitors in Mouse Embryonic Stem Cells

  • Kim, Young-Eun;Park, Jeong-A;Park, Sang-Kyu;Kang, Ho-Bum;Kwon, Hyung-Joo;Lee, Younghee
    • Development and Reproduction
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    • v.17 no.4
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    • pp.379-387
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    • 2013
  • Embryonic stem (ES) cells can self-renew and differentiate to various cells depending on the culture condition. Although ES cells are a good model for cell type specification and can be useful for application in clinics in the future, studies on ES cells have many experimental restraints including low transfection efficiency and transgene expression. Here, we observed that transgene expression after transfection was enhanced by treatment with histone deacetylse (HDAC) inhibitors such as trichostatin A, sodium butyrate, and valproic acid. Transfection was performed using conventional transfection reagents with a retroviral vector encoding GFP under the control of CMV promoter as a reporter. Treatment of ES cells with HDAC inhibitors after transfection increased population of GFP positive cells up to 180% compared with untreated control. ES cells showed normal expression of stem cell markers after treatment with HDAC inhibitors. Transgene expression was further enhanced by modifying transfection procedure. GFP positive cells selected after transfection were proved to have the stem cell properties. Our improved protocol for enhanced gene delivery and expression in mouse ES cells without hampering ES cell properties will be useful for study and application of ES cells.

Impact of Time Perspective on the Internet and Mobile Phone Addiction of Primary and Middle School Students (초등.중학생의 시간관이 인터넷과 휴대폰 중독에 미치는 영향)

  • Park, Chan-Jung;Kim, Dong-Hwan;Hyun, Jung-Suk
    • Journal of The Korean Association of Information Education
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    • v.15 no.3
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    • pp.399-411
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    • 2011
  • In the existing researches about the Internet and mobile phone addition for primary and secondary school students, the major addiction testing measurements are personal parameters such as obsession, self-efficacy, and self-control and environmental parameters such as parents, friends, schools, community factors, and mass media. Those researches have focused on the interaction objects between a student and him/herself, parents, friends, schools, or society. While the importance of time perspective has increased recently, there have rarely been the research that had focused on it in education arena. In this paper, we analyze how time perspective influences the Internet and mobile phone addiction levels of primary and middle school students. In order to do that, we surveyed 619 primary and middle school students and analyzed the results in this paper. And then, we renew the relative importance among existing factors for the two addictions and propose the way to prevent the two addictions.

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Generation of High Quality Geospatial Information Using Computer Vision Analysis of Line Type Digital Aerial Photogrammetry Camera Imagery (Line Type 디지털 항공사진측량 카메라 영상의 컴퓨터비전 해석을 통한 고품질 공간정보 생성)

  • LEE, Hyun-Jik
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.1
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    • pp.41-50
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    • 2020
  • The National Geographic Information Institute of Korea takes digital aerial photograph images every two years to make and modify/renew the digital map. The cameras for aerial photogrammetry to capture these digital aerial photographs are divided into frame types and line types. Computer vision analysis of aerial photograph images was only possible for frame type. Thus, in this study, Line type aerial photograph images was intended to generate geospatial information through computer vision analysis, and forest geospatial information was created as a method for the utilization of aerial picture images. As a result, geospatial information generated by computer vision analysis of line type aerial photograph images showed that RMSE of horizontal and vertical position errors was less than quadruple that of GSD. Forest geospatial information was generated using geospatial information generated by computer vision analysis. It was confirmed that extraction of the crown of tree and calculation of tree height are possible. Through this study, it is expected that utilization of aerial photograph images will be improved.

Improving the Standards of Midwifery Education and Practice and Extending the Role of a Midwife in Korean Women and Children′s Health Care

  • Lee, Kyung-Hye
    • Journal of Korean Academy of Nursing
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    • v.33 no.8
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    • pp.1111-1118
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    • 2003
  • Background. A midwife is a medical professional who has a nursing license, and is also licensed as a midwife with one additional year of education. In this globalization era, a midwife's role is increasing in importance for women and children's health care worldwide. Purpose. The primary purpose was to analyze midwifery education programs in Korea and other nations. The secondary purpose was to define strategies to improve midwifery education and practice, and to extend the role of a midwife women and children's health care in Korea. Methods & Results. 1) The definition of a midwife and midwifery practice recognized internationally by World Health Organization (WHO) and International Council of Nurse Midwives (ICNM) was identified. 2) Midwifery education programs of Korea, U.S.A., Sweden, Australia, and Japan, were investigated and discussed. 3) Core competencies for the basic midwifery practice suggested by ACNM of the U.S.A. were reviewed as standard of midwifery practice. 4) As for the midwifery education system, a Masters degree program in a college of nursing is suggested. 5) The role of a midwife includes not only health care of childbirth women and newborn babies, but also a lifelong health care of women as well as her family and children. Conclusion. An effort to extend the midwife's role and to improve service is imperative. The Laws/Acts related to midwives should be revised in regard to education, and practices, and the national examination for midwifery licensure needs revision to qualify for international approval. Also, midwifery curriculum and standards of practice need to be evaluated periodically, and an effective system needs to be established to renew midwife licenses.