• 제목/요약/키워드: relaxin

검색결과 16건 처리시간 0.024초

Successful Birth of Pups Produced by GnRH-induced Estrus and Natural Mating in Captive Red Fox (Vulpes vulpes)

  • Yong, Hwan-Yul;Bae, Bok-Soo;Kim, Seung-Dong;Lim, Yang-Mook;Ha, Yong-Hee;Oh, Chang-Sik;Kim, Myoung-Ho;Jo, Sin-Il;Yoo, Mi-Hyun;Jeong, Yu-Jeong;Ro, Sang-Chul
    • 한국수정란이식학회지
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    • 제25권4호
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    • pp.287-290
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    • 2010
  • On January 6, 2010, two months earlier than normal breeding season, a red fox vixen was implanted with synthetic GnRH analogue, Deslorelin. Blood was sampled every 2~3 days from the day of implant to identifying spermatozoa on stains of epithelial cells. Estradiol and progesterone were examined. Even though the vixen was in non-breeding season, she was mated by a male fox. Pregnancy was confirmed by canine pregnancy detection kit that detect relaxin released from placenta. Four healthy pups were born on March 9, 2010. This is the first report showing synthetic GnRH can activate ovarian function and lead to fertile estrus of red fox in non-breeding season.

향나무 추출물의 Galectin-3 저해에 의한 암 전이 억제 효과 (Anti-Metastatic Activity of Juniperus chinensis Extract by Galectin-3 Inhibition)

  • 이경호;이기형
    • 한국식품영양학회지
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    • 제25권4호
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    • pp.713-718
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    • 2012
  • 향나무 에탄올 추출물에 대한 암 전이 억제 효과를 측정하기 위하여 세포 수준에서 암 전이에 밀접히 관련되어 있는 galectin-3에 대한 억제 효과를 colon 26-M3.1 lung carcinoma에서 측정하였다. 향나무 추출물 $5{\mu}g/m{\ell}$, $50{\mu}g/m{\ell}$$500{\mu}g/m{\ell}$ 처리 시, 농도 의존적으로 galectin-3에 대한 저해 효과를 나타내었다. 한편, 암 전이 관련 있는 또 다른 단백질로 MMP 효소에 대한 직접적인 억제효과를 측정한 결과, 향나무 추출물 $5{\mu}g/m{\ell}$, $50{\mu}g/m{\ell}$$500{\mu}g/m{\ell}$ 처리 시 직접적으로 MMP-1, MMP-2 및 MMP-9 효소에 대해서 농도의존적인 저해 효과는 나타났으나, 강한 활성으로 평가되지는 못하였다. Colon 26-M3.1 lung carcinoma을 이용한 in vivo mouse 모델에서 향나무 추출은 농도 의존적으로 전이 억제 효과를 나타내었고, MMP-2 활성화 물질인 relaxin과 병용투여 시, relaxin의 기능에 영향을 받지 않는 것으로 나타났다. 따라서 in vivo mouse 모델에서 나타난 암 전이 억제 효과는 galectin-3 저해로 인한 효과로 사료된다.

임신 중 요통에 관한 고찰 (A Review of Pregnancy Related Low Back Pain)

  • 조미숙;박래준
    • The Journal of Korean Physical Therapy
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    • 제15권4호
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    • pp.431-441
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    • 2003
  • Pregnancy and puerperium are associated with significant changes in pschological and physiologic health status. Back and pelvic pain is common in pregnancy with prevalence figures in the range of $48\%-90\%$. The pain starts during pregnancy and often disappears soon after childbirth. But the prevalence of such pain four to six months post postpartum is report to be $25-40\%$. In $10-15\%$ of the case the pain become chronics, that is persisting for more than three months after childbirth. Low back pain and pelvic pain maybe caused by several factors related to changes that occur naturally during pregnancy. Changes in the center of gravity can create a strain on weight-bearing structures in bone. Pregnancy related hormones, relaxin, create general laxity of collagenous tissue. Another factor found to be a possible primary or contributing cause for law back and hip symptoms are leg length inequality, weight gain and changes in foot function. This article outlines the physiological and biomechanical changes that occur during pregnancy which have been reported to be possible causes of low back and pelvic pain And then, examination, diagnosis, evaluation and treatment of the woman during pregnancy are described. Standard treatment for low back pain and pelvic pain in pregnancy includes education in anatomy and kinesiology, back-strengthening exercise, training of the abdominal muscles and body posture correction. So, most woman during pregnancy require individual consultation and physiotherapist.

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