• Environmental Analysis Health and Toxicology
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• v.20 no.4 s.51
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• pp.343-350
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• 2005

In order to investigate the of effects of nalbuphine on immune system in mice, we examined the various immunological parameters. After single oral administration of nalbuphine (130, 260, 390 mg/kg, i.p.) to female ICR mite, the weights of bodies and organs (thymus, spleen, liver, kidney), and hematological parameters were examined on day 2, 4, 6, and 8. The increased rate of body weight, relative weight of organ, and hematological parameters in nalbuphine -treated groups, were not significantly changed when compared with control group. However, number of WBC was decreased by the treatment of nalbuphine. To assess the effects of nalbuphine on humoral immune responses, splenic IgM plaque forming cell (PFC) and serum IgM were assayed. When nalbuphine wat administered after immunization with SRBC, but not before immunization, splenic IgM PFC and ,serum IgM level against SRBC were significantly lowered in a dole -dependent manner. These results indicate that the suppressive effects of nalbuphine on primary humoral immune response may be dependent on the timing of its administration relative to the initial antigenic sensitization.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.1
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• pp.134-140
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• 1997

Objectives of this study were to determine effects of insulin on acetyl-CoA carboxylase (ACC) activity and correlate this activity with relative amounts of ACC in MAC-T cells. MAC-T cells were grown in Medium 199 supplemented with fetal bovine serum (5%), cortisol ($1{\mu}g/ml$), and insulin ($1{\mu}g/ml$). At confuluence, the cells were transferred to $100mm^2$ culture dishes coated with the extracelluar matrix. After 10 h of incubation, the media were replaced with media without fetal bovine serum and the concentration of insulin was lowered to 5 ng/ml. After 24 h, the media were changed to contain the varying concentrations of insulin and incubations continued for 48 h. The addition of insulin resulted in increases in the specific activity of ACC. The maximal effects of insulin on the ACC activity occurred at concentrations of insulin, 1,000 ng/ml. In contrast, the relative change in lactate dehydrogenase (LDH) activity in response to increasing insulin concentration was minimal as compared to the effects of insulin on ACC. Transblot and enhanced chemiluminescence (ECL) analysis indicated that the increase in ACC activity in MAC-T cells caused by insulin were due to actual increases in amounts of enzyme.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2010.04a
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• pp.31-34
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• 2010

The rover positioning is performed by estimating the baseline vector components in doubledifference positioning mode. This means that relative displacement due to the tide effects can be neglected when the distance between the reference and rover station is relatively short. However, the tide effects should be carefully modeled and removed as the baseline length gets longer. In this study, the relative displacement over the Korean Peninsula due to tide effects are examined through the numerical analysis. The results show that the tide modeling is required for the precise GPS positioning at cm-level accuracy.

• Phonetics and Speech Sciences
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• v.3 no.3
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• pp.69-75
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• 2011

This paper investigates phrase positional effects on the timing of F0 (pitch) peaks in Tokyo Japanese disyllabic words with varying accent type (HL or LH) and phrase position (final or non final). The F0 peak timing was normalized by the total word duration ('normalized H timing'). The normalized H timing was significantly affected by accent type and phrase position. The H timing was later in the LH accent type than in the HL accent type, and in non final positions than in final positions. In addition, to examine the validity of the quantitative results, different models of phrase position effects were compared by measuring H timing in two approaches: normalization versus relative distance measures. For the normalization measures, the H timing was measured as the time of the F0 peak divided by the total word duration or by the duration of the tone bearing syllable. For the relative distance measures, the H timing was measured as the distance in milliseconds from the end of the word or from the end of the associated syllable. The best model was the normalization by the total word duration, rather than by the duration of the tone bearing syllable. This means that phrase positional effects on the timing of F0 peaks in Japanese disyllabic words are best modeled in terms of proportion of the total word duration.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.293-296
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• 2002

This work presents the reconstruction of impact force produced by the collision between two elastic structures. The 2-DOF impactor was designed. The shape control of impact farce using correlations of the dynamic characteristics and impact force history between two elastic structures is accomplished. The effects of the relative motion between impactor and elastic structure on the impact force shape are studied. Reconstruction characteristics of impact force in cantilever beam are reviewed.

• Journal of the Korean Ceramic Society
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• v.31 no.12
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• pp.1467-1474
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• 1994

The effects of the dispersion, drying, and binder burning-out on the green-microstructures of gelcasted alumina were studied. The slip consisting of 55 vol% alumina powder and 5 wt% organic materials was well-dispersed by adding 0.28 wt% polyelectrolyte polymer. Green bodies were dried at >85% relative humidity at room temperature. Green-microstructures were observed to be depended on the heating rate during binder burnout. Constant drying rate was not observed in drying process of gelcasted alumina. Sintered body showed its relative density higher than 99% when it was sintered at 1$600^{\circ}C$ for 2 hours.

• Bulletin of the Korean Chemical Society
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• v.1 no.1
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• pp.17-22
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• 1980

The CNDO/2 method was used to compute relative stabilities of various configurations and conformations of acetamide, N-methylacetamide and diacetamide and their protonated forms. It was found that: (a) nonbonded interactions play important roles in determining structural preferences of the compounds, (b)$n-{\sigma}^{\ast}$ "throughbond" interactions always favor cis-protonation (relative to C-N).

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.9
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• pp.1371-1377
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• 2002

During a 5-yr period, 1994-1998, pre-weaning and weaning data were collected on 591 calves produced by mating either straightbred Jersey, straightbred Limousin or $F_1$ (Limousin${\times}$Jersey) bulls to mature purebred Jersey or Limousin cows. Traits recorded included birth and weaning weight, height, length, girth, fat depth and a measure of muscle (ratio of stifle to hip width expressed as a percentage). All traits were analyzed assuming a model with sire and dam random effects that included effects of year and date of birth, sex, breed and year${\times}$sex interaction. Main effects were generally significant with few exceptions. Direct genetic effects were large for weight, height, girth and muscle with a breed trend from purebred Jersey (small) to purebred Limousin (large). At weaning, the maternal effect of the Jersey dam was positive for weight (10.9${\pm}$4.9 kg), girth (3.7${\pm}$1.0 cm) and muscle (6.0${\pm}$0.9%). Heterosis was highly significant and positive only for fat depth (1.5${\pm}$0.2 mm) with the $F_1$ progeny being the fattest, followed by the backcrosses, then purebred Jersey and purebred Limousin. Also, significant (p<0.001) but negative heterosis was observed for weight, girth and muscle. The change in ranking for fat depth relative to other traits is a reflection of the large heterotic effects relative to direct effects on fat depth. Epistatic effects were not significant on any trait at birth or weaning. This study has indicated the possibility of exploiting the positive heterotic and maternal effects for fat depth and muscularity to meet specific meat quality and quantity demand by consumers.

• Bulletin of the Korean Chemical Society
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• v.26 no.11
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• pp.1761-1766
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• 2005

Solvolysis rates of isopropenyl chloroformate (3) in water, $D_2O$, $CH_3OD$ and in aqueous methanol, ethanol, 2,2,2-trifluoroethanol (TFE), acetone, 1,4-dioxane as well as TFE-ethanol at 10 ${^{\circ}C}$ are reported. Additional kinetic data for pure water, pure ethanol and 80%(w/w) 2,2,2-trifuoroethanol (T)-water (W) at various temperatures are also reported. These rates show the phenomena of maximum rates in specific solvents (30% (v/v) methanol-water and 20% (v/v) ethanol-water) and, variations in relative rates are small in aqueous alcohols. The kinetic data are analyzed in terms of GW correlations, steric effect, kinetic solvent isotope effects (KSIE), and a third order model based on general base catalysis (GBC). Solvolyses based on predominately stoichiometric solvation effect relative to medium solvation are proceeding in 3 and the results are remarkably similar to those for p-nitrobenzoyl chloride (4) in mechanism and reactivity.

• Journal of the Korean Society of Safety
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• v.28 no.5
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• pp.66-70
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• 2013

This study examined the relative effects of education and eco-IVIS(in-vehicle information system) to reduce fuel consumption and greenhouse gas emissions. Also the study investigated the increasing of driving workload when drivers interact with intervention technique. Thirty participants randomly assigned into two groups(training and eco-IVIS) and conducted driving before and after the each intervention technique. While driving, we observed three driving behaviors: Frequency of excessive RPM, percent of speeding, and mean fuel efficiency. Also the Driver Activity Load Index was used to rate participants' subjective ratings of driving workload. Although the results showed positive impact of both education and eco-IVIS to increasing the eco-driving behaviors, eco-IVIS was more effective than education. However, we found comparable level of driving workload in the education and eco-IVIS.