• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.7
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• pp.67-77
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• 2016

In this paper, we propose an algorithm for open/closed eye detection based on modified Hausdorff distance. The proposed algorithm consists of two parts, face detection and open/closed eye detection parts. To detect faces in an image, MCT (Modified Census Transform) is employed based on characteristics of the local structure which uses relative pixel values in the area with fixed size. Then, the coordinates of eyes are found and open/closed eyes are detected using MHD (Modified Hausdorff Distance) in the detected face region. Firstly, face detection process creates an MCT image in terms of various face images and extract criteria features by PCA(Principle Component Analysis) on offline. After extraction of criteria features, it detects a face region via the process which compares features newly extracted from the input face image and criteria features by using Euclidean distance. Afterward, the process finds out the coordinates of eyes and detects open/closed eye using template matching based on MHD in each eye region. In performance evaluation, the proposed algorithm achieved 94.04% accuracy in average for open/closed eye detection in terms of test video sequences of gray scale with 30FPS/$320{\times}180$ resolution.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3607-3612
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• 2013

Introduction: Reported prognostic roles of hypoxic inducible factor (HIF) expression in non-small cell lung cancer (NSCLC) have varied. This meta-analysis aimed to examine the relationship between HIF expression and clinical outcome in NSCLC patients. Methods: PubMed were used to identify relevant literature with the last report up to December $20^{th}$, 2012. After careful review, survival data were collected from eligible studies. We completed the meta-analysis using Stata statistical software (Version 11) and combined hazard ratio (HR) for overall survival (OS). Subgroup specificity, heterogeneity and publication bias were also assessed. All of the results were verified by two persons to ensure accuracy. Results: Eight studies were finally stepped into this meta-analysis in which seven had available data for HIF-$1{\alpha}$ and three for HIF-$2{\alpha}$. Combined HRs suggested that higher expression of $HIF1{\alpha}$ had a negative impact on NSCLC patient survival (HR=1.50; 95%CI=1.07-2.10; p=0.019). The expression of HIF-$2{\alpha}$ was also relative to a poorer survival (HR=2.02; 95%CI=1.47-2.77; p=0.000). No bias existed in either of the two groups. Conclusion: This study suggests that elevations of HIF-$1{\alpha}$ and HIF-$2{\alpha}$ expression are both associated with poor outcome for patients with NSCLC. The data support further and high quality investigation of HIF expression for predicting poor outcome in patients with NSCLC.

• Korean Journal of Food Science and Technology
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• v.47 no.1
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• pp.1-5
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• 2015

This study aimed to simultaneously determine various carotenoids from different colored paprika using an ultra performance liquid chromatograph (UPLC) equipped with a HSS T3 column. Analysis was performed at 450 nm using gradient conditions with acetonitrile/methanol/methylene chloride (65/25/10) and distilled water. We improved the peak resolution and performed carotenoid analysis within 30 min. We qualitatively analyzed 11 carotenoids (neoxanthin, capsorubin, violaxanthin, capsanthin, zeaxanthin, lutein, ${\alpha}$-cryptoxanthin, ${\beta}$-cryptoxanthin, lycopene, ${\alpha}$-carotene, and ${\beta}$-carotene). For the validation of UPLC methods, we validated the precision and accuracy of capsanthin. Capsanthin showed good linearity ($R^2$=0.9998) in the concentration range of $1-200{\mu}g/mL$ with 2.4 and $7.2{\mu}g/mL$ of limit of detection (LOD) and limit of quantification (LOQ), respectively. The relative standard deviation (RSD) for intra- and inter-day precision was less than 3.83%. Recovery was in the range of 91.86-99.87%. We quantitatively analyzed carotenoid contents from 8 different colored paprika (red, orange, yellow, and green). The most abundant carotenoids were capsanthin in red paprika, and zeaxanthin in orange, yellow, and green paprika.

• Journal of Pharmacopuncture
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• v.17 no.4
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• pp.36-49
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• 2014

Objectives: Quercetin and curcuminoids are important bioactive compounds found in many herbs. Previously reported high performance liquid chromatography ultraviolet (HPLC-UV) methods for the detection of quercetin and curcuminoids have several disadvantages, including unsatisfactory separation times and lack of validation according the standard guidelines of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. Methods: A rapid, specific, reversed phase, HPLC-UV method with an isocratic elution of acetonitrile and 2% v/v acetic acid (40% : 60% v/v) (pH 2.6) at a flow rate of 1.3 mL/minutes, a column temperature of $35^{\circ}C$, and ultraviolet (UV) detection at 370 nm was developed. The method was validated and applied to the quantification of different types of market available Chinese medicine extracts, pills and tablets. Results: The method allowed simultaneous determination of quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin in the concentration ranges of $0.00488-200{\mu}g/mL$, $0.625-320{\mu}g/mL$, $0.07813-320{\mu}g/mL$ and $0.03906-320{\mu}g/mL$, respectively. The limits of detection and quantification, respectively, were 0.00488 and $0.03906{\mu}g/mL$ for quercetin, 0.62500 and $2.50000{\mu}g/mL$ for bisdemethoxycurcumin, 0.07813 and $0.31250{\mu}g/mL$ for demethoxycurcumin, and 0.03906 and $0.07813{\mu}g/mL$ for curcumin. The percent relative intra day standard deviation (% RSD) values were $0.432-0.806{\mu}g/mL$, $0.576-0.723{\mu}g/mL$, $0.635-0.752{\mu}g/mL$ and $0.655-0.732{\mu}g/mL$ for quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin, respectively, and those for intra day precision were $0.323-0.968{\mu}g/mL$, $0.805-0.854{\mu}g/mL$, $0.078-0.844{\mu}g/mL$ and $0.275-0.829{\mu}g/mL$, respectively. The intra day accuracies were 99.589%-100.821%, 98.588%-101.084%, 9.289%-100.88%, and 98.292%-101.022% for quercetin, bisdemethoxycurcumin, demethoxycurcumin and curcumin, respectively, and the inter day accuracy were 99.665%-103.06%, 97.669%-103.513%, 99.569%-103.617%, and 97.929%-103.606%, respectively. Conclusion: The method was found to be simple, accurate and precise and is recommended for routine quality control analysis of commercial Chinese medicine products containing the flour flavonoids as their principle components in the extracts.

• Journal of Digital Convergence
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• v.16 no.8
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• pp.71-79
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• 2018

This study discussed the meaning of a drone, and especially drone journalism and legal and ethical issues around that, at an introductory dimension, which is used in various social bases, but is still just an academic discussion at the beginning stage. As a methodology, content analysis was used. It seems that drone journalism has high diffusibility as a technology with high 'relative advantage', 'compatibility', 'trial ability' and 'observability' and low 'complexity' in terms of the diffusion of innovation theory. However, it will be very likely that controversies will be raised, such as safety issue due to collision and crash, a dispute over violation of privacy that may seriously infringe privacy like individual portrait rights and a controversy about the accuracy and source of information as drone filming low price and ease of use. Suggest solutions to legal and ethical issues based on existing research. Technical stability is required. Also, it is necessary to change the awareness of journalists about the drones coverage and to educate ethics, and it is necessary to establish social public opinion on issues such as privacy violation and establish system and legal measures through it. Future research is expected to carry out empirical research including journalists and public awareness surveys.

• Journal of the Korean earth science society
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• v.38 no.7
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• pp.496-510
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• 2017

This study presents a new nationwide quantitative precipitation estimation (QPE) based on the hybrid surface rainfall (HSR) technique using the weather radar network of Korea Meteorological Administration (KMA). This new nationwide HSR is characterized by the synthesis of reflectivity at the hybrid surface that is not affected by ground clutter, beam blockage, non-meteorological echoes, and bright band. The nationwide HSR is classified into static (STATIC) and dynamic HSR (DYNAMIC) mosaic depending on employing a quality control process, which is based on the fuzzy logic approach for single-polarization radar and the spatial texture technique for dual-polarization radar. The STATIC and DYNAMIC were evaluated by comparing with official and operational radar rainfall mosaic (MOSAIC) of KMA for 10 rainfall events from May to October 2014. The correlation coefficients within the block region of STATIC, DYNAMIC and MOSAIC are 0.52, 0.78, and 0.69, respectively, and their mean relative errors are 34.08, 30.08, and 40.71%.

• Sleep Medicine and Psychophysiology
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• v.23 no.2
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• pp.68-76
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• 2016

Objectives: To find evidence that sleep is necessary for normal brain function, thus indicating that declines in both sleep quality and quantity are related to worse performance of many daily tasks and deteriorated physical functions. The present study investigates the relationships of balance control and reaction time with sleep quality. Methods: 58 healthy (male 20, female 38) volunteers with informed consent participated in this study. The Self-reported Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality and relevant factors, and the subjects were divided into groups A (PSQI < 5) and B ($PSQI{\geq}5$) based on this index. Static balance control and reaction time to visual stimuli were conducted to assess their relationship with sleep quality. Results: Group B exhibited excessive daytime sleepiness significantly more often compared to group A. Static balance control did not markedly change relative to sleep quality, but reaction time and error to visual stimuli were significantly increased in group B compared to group A. Conclusion: These findings indicate that a decline in sleep quality can result in delayed reactions, as well as decreased accuracy of these reactions. They also suggest that low sleep quality may be associated with changes in physical functions, including balance control through reduced selective attention.

• Journal of Korean Society of Forest Science
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• v.102 no.4
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• pp.467-476
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• 2013

Site index information given from forest site map only exist in the sampled locations. In this study, site index for unsampled locations were estimated using kriging interpolation method which can interpolate values between point samples to generate a continuous surface. Site index of Pinus densiplora in Danyang area were calculated using Chapman-Richards model by plot unit. Then site index for unsampled locations were interpolated by theoretical variogram models and ordinary kriging. Also in order to assess parameter selection, cross-validation was performed by calculating mean error (ME), average standard error (ASE) and root mean square error (RMSE). In result, gaussian model was excluded because of the biggest relative nugget (37.40%). Then spherical model (16.80%) and exponential model (8.77%) were selected. Site index estimates of Pinus densiplora throughout the entire area in Danyang showed 4.39~19.53 based on exponential model, and 4.54~19.23 based on spherical model. By cross-validation, RMSE had almost no difference. But ME and ASE from spherical model were slightly lower than exponential model. Therefore site index prediction map from spherical model were finally selected. Average site index from site prediction map was 10.78. It can be expected that regional variance can be considered by site index prediction map in order to estimate forest biomass which has big spatial variance and eventually it is helpful to improve an accuracy of forest carbon estimation.

• Economic and Environmental Geology
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• v.40 no.3 s.184
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• pp.295-306
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• 2007

In this study, we predicted areas vulnerable to ground subsidence near abandoned underground coal mine at Sam-cheok City in Korea using a probability (frequency ratio) model with Geographic Information System (GIS). To extract the factors related to ground subsidence, a spatial database was constructed from a topographical map, geo-logical map, mining tunnel map, land characteristic map, and borehole data on the study area including subsidence sites surveyed in 2000. Eight major factors were extracted from the spatial analysis and the probability analysis of the surveyed ground subsidence sites. We have calculated the decision coefficient ($R^2$) to find out the relationship between eight factors and the occurrence of ground subsidence. The frequency ratio model was applied to deter-mine each factor's relative rating, then the ratings were overlaid for ground subsidence hazard mapping. The ground subsidence hazard map was then verified and compared with the surveyed ground subsidence sites. The results of verification showed high accuracy of 96.05% between the predicted hazard map and the actual ground subsidence sites. Therefore, the quantitative analysis of ground subsidence near abandoned underground coal mine would be possible with a frequency ratio model and a GIS.

• Korean Journal of Food Science and Technology
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• v.43 no.1
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• pp.1-5
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• 2011

It is possible that veterinary medicines remain in livestock food products, according to the use of many and various veterinary medicines to protect against disease when livestock animals are breed in limited space. Concentrated and continuous monitoring of residues is needed due to increases in resistance to antibiotics and side effects by eating livestock food products. We developed an analysis method for detecting streptomycin, dihydrostreptomycin, neomycin, gentamicin and spectinomycin in meat using LC/MS/MS and measured sensitivity, precision, accuracy, linearity and recovery according to CODEX guidelines to acquire confidence in the analysis method. Based on the results, we acquired good sensitivity compared to the maximum residue limit (MRL) as limits of detection (LOD) were 0.002-0.016 mg/kg and limits of quantification (LOQ) were 0.006-0.050 mg/kg. The analysis method satisfied the CODEX guidelines. The linearity ($r^2$) values of aminoglycoside antibiotics were 0.9936-0.9980, recoveries were 60-110% and relative standard deviations (RSD) were within 15%. As a result of monitoring for residues in a total 250 samples of livestock foods such as pork, chicken, and beef by the confirmed method, dihydrostreptomycin and gentamicin were detected in 5 pork samples. The residues of these antibiotics were within the MRLs. Thus, the detection ratio was 2% as 5 samples were identified from 250 samples.