• Journal of Oriental Neuropsychiatry
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• v.22 no.1
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• pp.13-23
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• 2011

Objectives : The aim of this survey study is to analysis clinical symptoms and patterns of dementia patients. The results of this study will be used to support development of the oriental herbal medicine for dementia. Methods : Clinical data were collected from 41 dementia patients and 20 aged persons who have no cognitive impairment in 3 sites including 2 hospitals and 1 sanatorium. 'The instrument of oriental medical evaluation for dementia' is used to evaluate clinical symptoms and patterns of all subjects. Results : 1. Subjects of deficiency syndrome patterns were nearly three times more than subjects of excess syndrome patterns. 2. In dementia patient group, the average rate for 4 clinical symptoms, related with treatment principle of clear heat, was 26.9%. 3. The average rate for 4 clinical symptoms, related with condition of urine and feces, was 15.6%. 4. The average rate for 5 clinical symptoms, related with anger, irritation, anxiety and restlessness, was 40.0%. Conclusions : 1. It is needed to develop new herbal medicine for dementia focuing on clear heat, anger, irritation, anxiety, restlessness, and condition of urine and feces. 2. 'The instrument of oriental medical evaluation for dementia' has strong tendency that excessively reflects general geriatric symptoms, related to deficiency syndrome patterns. so, more clinical symptoms of excess syndrome should be added in this tool.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.20 no.1
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• pp.22-26
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• 2017

Purpose: The diagnosis of cow's milk (CM) allergy is a challenge. The Cow's Milk-related-Symptom-Score ($CoMiSS^{TM}$) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the $CoMiSS^{TM}$ was evaluated in three clinical trials. Methods: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 challenge test on the month-1 $CoMiSS^{TM}$, adjusting for baseline $CoMiSS^{TM}$ using a logistic regression model. In addition a logistic regression model was also fitted to the month-1 challenge test result with the change in $CoMiSS^{TM}$ from baseline as a predictor. Results: Results suggest that infants having a low $CoMiSS^{TM}$ (median, 5) after 1 month dietary treatment free from intact CM protein have a significant risk of having a positive challenge test (odds ratio, 0.83; 95% confidence interval, 0.75-0.93; p=0.002). Pooled data suggest that the change in $CoMiSS^{TM}$ from baseline to month-1 can predict CM related symptoms as a confirmed diagnosis according to the challenge test at month-1. However, in order to validate such a tool, infants without CM related symptoms would also need to be enrolled in a validation trial. A concern is that it may not be ethical to expose healthy infants to a therapeutic formula and a challenge test. Conclusion: Pooled data analysis emphasizes that the $CoMiSS^{TM}$ has the potential to be of interest in infants suspected to have CM-related-symptoms. A prospective validation trial is needed.

• Journal of muscle and joint health
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• v.27 no.2
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• pp.199-209
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• 2020

Purpose: This study examined the prevalence of depressive symptoms and psycho-behavioral factors affecting depressive symptoms in patients with osteoarthritis. Methods: This cross-sectional study enrolled a convenience sample of 157 patients with osteoarthritis in a university hospital between March and December 2018. Depressive symptoms, osteoarthritis function, therapeutic self-efficacy, and health-related quality of life (QoL) were measured using structured questionnaires. Logistic regression analysis was used to investigate factors affecting depressive symptoms. Results: The mean age of participants was 73.3 years with 76.4% of them being women. The prevalence of depressive symptoms was 38.5%. Patients with depressive symptoms were more likely to be currently smoking and had an occupation and worse flexibility function associated with osteoarthritis. Whereas they were less likely to engage in regular physical activity and had a low level of therapeutic self-efficacy and perceived health-related QoL. Conclusion: Therapeutic self-efficacy to regular physical activity, including flexibility function may be primary factors influencing depressive symptoms in patients with osteoarthritis. With the management of osteoarthritis, psycho-behavioral factors should be considered in developing interventions to prevent depressive symptoms in patients with osteoarthritis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.4919-4926
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• 2013

The purpose of this study was to examine the stress of health-related majoring students on their physical and temporomandibular joint symptoms. The subjects were 283 college students in Chungcheongnam-do province from September 1 to November 30, 2012. The data were analyzed using SPSS 18.0(SPSS 18.0 K for window, SPSS Inc, USA) with the level of significance as 0.05. The findings of the study were as follows: There were significant differences among the university students in stress according to age, academic year, smoking and snack intake. Significant differences were found in digestive symptoms according to gender, academic year, drinking and snack intake, and there were significant differences in temporomandibular joint symptoms. Stress had a significant correlation to physical symptoms and temporomandibular joint symptoms. As for the influence of stress on physical symptoms and temporomanbular joint symptoms. In this study, how to help college students to relieve stress in a sound manner, to promote their physical, mental and oral health and ultimately to lead a sound college life should carefully be considered.

• Journal of Korean Clinical Nursing Research
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• v.23 no.1
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• pp.20-29
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• 2017

Purpose: The purpose of this study was to investigate symptoms experienced by patients who reported fever at the emergency room (ER) and to identify any existing cluster of symptom related to fever. Methods: The study used a retrospective and descriptive design with secondary data analysis. Data were abstracted from 665 medical records of patients with fever who visited ER from September 1, 2015 to August 31, 2016 at a tertiary hospital. Results: The most frequently reported symptoms included cold (43.9%), myalgia (24.1%), headache (16.2%), general weakness (15.3%), respiratory symptoms (12.3%), gastrointestinal (GI) symptoms (12.0%), mental change (4.5%), sweating(1.8%), and warmth (0.9%). Analysis of the symptoms related to fever revealed seven symptom clusters; Cluster 1 (n=190) included cold (100%) and myalgia (28.9%); Cluster 2 (n=37), headache (100%) and myalgia (32.4%); Cluster 3 (n=33), GI symptoms (100%), general weakness, headache, and cold; Cluster 4 (n=34), cold (100%), myalgia, headache, and respiratory symptoms; Cluster 5 (n=241), respiratory symptoms (10.8%); Cluster 6 (n=76): myalgia (75.0%) and general weakness, and Cluster 7 (n=54), cold (87.0%), general weakness, and respiratory symptoms. Conclusion: The results of this comprehensive symptom assessment are hoped to be helpful in developing better symptom management for ER patients with fever than before. Further research is warranted to verify the symptom clusters of this study in different clinical settings.

• Journal of Oral Medicine and Pain
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• v.47 no.3
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• pp.109-116
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• 2022

Purpose: This study was conducted to analyze the clinical characteristics and distribution of the tongue-related diagnoses in patients with tongue symptoms. Methods: The subjects were patients who visited Chosun University Dental Hospital with tongue symptoms from January 1, 2021, to December 31, 2021. We analyzed 491 patients (139 males and 352 females) with tongue-related diagnostic code names in the Korean Standard Classification of Disease (KCD) in the Electronic Medical Record (Dentopinformation Technology Co., Seoul, Korea). Results: On analyzing the diagnoses of tongue diseases using the KCD, glossopyrosis (44.8%) and painful tongue (15.2%) showed high rates. Of the 491 patients, 139 (28.3%) were males and 352 (71.7%) were females, and the average age was 58.1 years. As for systemic diseases, there were many patients with diseases of the circulatory system (27.0%) and endocrine, nutritional, and metabolic diseases (13.7%). Tongue symptoms were discomfort in 58 patients, pain in 329 patients, paresthesia in 10 patients, burning sensations in 222 patients, dysgeusia in 25 patients, dryness in 110 patients, fissures in 57 patients, and other symptoms in 72 patients. Areas with tongue symptoms were the anterior area in 102 patients, the lateral area in 140 patients, the posterior area in 12 patients, the dorsal area in 140 patients, the ventral area in 42 patients, and which area in 126 patients overall. Patients with burning mouth syndrome and oral candidiasis had significantly more tongue symptoms. Conclusions: Patients with tongue symptoms exhibited a variety of tongue diseases. Tongue symptoms were more common in women over 50 years of age and were frequently seen in patients with burning mouth syndrome and oral candidiasis.

• Women's Health Nursing
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• v.10 no.2
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• pp.162-170
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• 2004

Purpose: The purpose of this study was to differentiate between women with three perimenstrual symptom severity patterns : premenstrual syndrome(PMS), premenstrual magnification(PMM), and low symptom(LS), and to explore the related dietary factors to premenstrual symptoms. Method: Women were asked to keep a diary record of perimenstrual symptoms and food intake for 50 days. Result: Symptom patterns were defined for 26 among 38 women ; Eight(21.1%) demonstrated a PMS pattern, three(7.9%) demonstrated a PMM pattern, and fifteen(39.5%) exhibited a LS pattern. There were significant differences in symptom scores during the premenstrual phase($x^2=19.30$, p=.000), menstrual phase($x^2=13.32$, p=.001), and post menstrual phase($x^2=9.93$, p=.007) for three groups. Protein, vit E, vit C, niacin, folic acid, and phosphorus in the premenstrual phase, and energy, and vit B6 in the menstrual period were significantly different between the three groups. Among dietary compositions, amino acids, lipids, fatty acids, saturated fatty acids, natrium, vit B6, niacin, and vit E were negatively related to PMS symptoms. Conclusion: Pattern of perimenstrual symptoms should be differentiated for individualized PMS management. As a more efficient diet assessment for PMS women, randomized nutritional analysis during the 3 phases of the menstrual cycle should be done and a replication study is necessary with a larger sample.

• Korean Journal of Occupational Health Nursing
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• v.24 no.3
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• pp.162-172
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• 2015

Purpose: This study was to explore factors affecting musculoskeletal symptoms of the child care centers' teachers in Korea. Methods: This study was a descriptive research, using a cross-sectional survey. Convenience samples of 230 child care centers' teachers aged 20 to 65 were selected. A self-administered questionnaire was used to measure general characteristics, job-related characteristics, exercise habit, fatigue and musculoskeletal symptoms of the body parts. The data were analyzed with the SPSS/WIN 21.0 program. Results: Shoulder pain (73.5%), low back pain (72.6%) and wrist/hand pain (57.8%) were the most common musculoskeletal symptoms. Shoulder pain significantly differed depending on the age of children in charge at the child care center (p<.047). The exercise habit was related to low back pain (p<.028) and the career was linked to wrist/hand pain (p<.046). The logistic regression analysis revealed exercise habit and fatigue were the risk factors on musculoskeletal symptoms of many body parts. Conclusion: These results suggest that interventions targeting the child care centers' teachers should be considered job-related characteristics and fatigue in order to prevent musculoskeletal disorder. Thus, there continues to be a need to develop exercise program for the child care centers' teachers.

• Journal of Korean Academy of Nursing
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• v.43 no.1
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• pp.81-90
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• 2013

Purpose: This study was done to test structural equation modeling of health-related quality of life (QOL) of men with obstructive sleep apnea in order to identify parameters affecting QOL and provide guidelines for interventions and strategies to improve QOL in these patients. Methods: Model construction was based on 'The conceptual model of patient outcome in health-related QOL' by Wilson and Cleary, using the variables; age, physiological factors, social support, cognitive appraisal, symptoms and QOL. Participants were 201 adult male patients recruited at a tertiary university hospital in Seoul. Data were collected via questionnaires, polysomnography, and clinical records. Results: Age and symptoms directly influenced QOL. Social support and cognitive appraisal about sleep did not have a direct influence on QOL, but indirectly affected it via symptoms. QOL was lower in patients who were younger and had more severe symptoms. Symptoms were more severe for patients with lower social support and more dysfunctional cognitive appraisal. When social support was lower, cognitive appraisal was more dysfunctional. Conclusion: These results suggest it is necessary to not only manage symptoms, but also apply interventions to increase social support and cognitive appraisal about sleep in order to increase QOL in patients with obstructive sleep apnea.

• Journal of Korean Medical classics
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• v.36 no.3
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• pp.15-25
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• 2023

Objectives : This study aims to investigate a wide range of symptoms related to anger and their corresponding treatments as described in Traditional Korean Medical literature. Additionally, the study aims to propose key prescriptions for Intermittent Explosive Disorder(IED), thereby striving to explore potential therapeutic strategies. Methods : This comprehensive study examines the correlations between the pathologies, symptoms, and treatments related to anger, as described in the Yixuerumen (醫學入門), the Donguibogam (東醫寶鑑), and the Xiezhenglun (血證論), and their relevance to IED. Results : Anger impairs the liver, giving rise to a spectrum of symptoms including dry hair, headaches, dizziness, a bitter taste in the mouth, tinnitus, vomiting of blood, sharp chest and flank pains, abdominal discomfort, tremors, diarrhea, and hyperventilation. Furthermore, this heightened anger can serve as a potential trigger for strokes and, considering its potential to hinder recovery from various other conditions, calls for proactive therapeutic intervention. Conclusions : Severe anger has the potential to trigger strokes and hinder recovery from a range of illnesses, underscoring the necessity for tailored and proactive treatment based on the severity of symptoms. In the instance of IED, clinical application of the Danggui Luihuiwan (當歸蘆薈丸) is warranted.