• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2013년도 추계학술대회
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• pp.97-100
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• 2013

본 논문은 복잡한 배경 영상에서 필기체가 아닌 수평, 수직 성분이 많이 포함된 문자 검출 방법을 제안한다. 본 논문에서 검출하고자 하는 문자는 코너 성분이 많이 밀집되어 있으며 배경 영상은 그에 비해 코너 성분이 적고 드문드문하다는 특징을 이용하여 먼저 해리스 코너 검출기를 이용하여 전체 영상에서 코너를 검출한다. 검출된 코너들의 위치 정보를 이용해 밀집되어 있는 코너들을 클러스터링 함으로써 문자 영역을 검출한다. 검출된 문자 영역간의 위치 정보와 히스토그램 분포를 비교하여 비슷한 특징을 갖는 영역들을 합치고 문자 성분의 특징을 갖지 않는 영역은 필터링 하여 문자 영역을 개선한다. 문자 영역에서 R채널, G채널, B채널 각각의 채널에 대한 히스토그램 분포를 분석하여 문자를 검출한다.

• 농촌계획
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• 제20권4호
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• pp.145-155
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• 2014

Since greenhouse gas emissions increase continuously, the authorities have needed climate change countermeasure for adapting the acceleration of climate change damages. According to "Framework Act on Low Carbon, Green Growth", Korean local governments should have established the implementation plan of climate change adaptation. These guidelines which is the implementation plan of climate change adaptation should be established countermeasure in 7 fields such as Health, Digester/Catastrophe, Agriculture, Forest, Ecosystem, Water Management and Marine/Fisheries. Basically the Korean local governments expose vulnerable financial condition, therefore the authorities might be assessed the vulnerability by local regions and fields, in order to establish an efficient implementation plan of climate change adaptation. Based on this concepts, this research used 3 methods which are LCCGIS, questionnaire survey analysis and analysis of existing data for the multiphasic vulnerable assessment. This study was verified the correlation among 7 elements of climate change vulnerability by 3 analysis methods, in order to respond climate change vulnerability in rural areas, Seocheon-gun. If the regions were evaluated as a vulnerable area by two or more evaluation methods in the results of 3 methods' comparison and evaluation, those areas were selected by vulnerable area. As a result, the vulnerable area of heavy rain and flood was Janghang-eup and Maseo-myeon, the vulnerable area of typhoon was Janghang-eup, Masan-myeon and Seo-myeon. 3 regions (i.e. Janghang-eup, Biin-myeon, Seo-myeon) were vulnerable to coastal flooding, moreover Masan-myeon, Pangyo-myeon and Biin-myeon exposed to vulnerability of landslide. In addition, Pangyo-myeon, Biin-myeon and Masan-myeon was evaluated vulnerable to forest fire, as well as the 3 sites; Masan-myeon, Masan-myeon and Pangyo-myeon was identified vulnerable to ecosystem. Lastly, 3 regions (i.e. Janghang-eup, Masan-myeon and Masan-myeon) showed vulnerable to flood control, additionally Janghang-eup and Seo-myeon was vulnerable to water supply. However, all region was evaluated vulnerable to water quality separately. In a nutshell this paper aims at deriving regions which expose climate change vulnerabilities by multiphasic vulnerable assessment of climate change, and comparing-evaluating the assessments.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제21권1호
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• pp.17-22
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• 2010

Objectives ： Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by abnormalities of social functioning, communication and behavior. The association of the 7q21-34 region with ASD has been reported. The DLX6 gene, which is located at the 7q22 region, is one of the positional and functional candidate genes for ASD. We found that there is no association between DLX6 polymorphisms and ASD in the Korean male population. Methods ： We selected three single nucleotide polymorphisms (SNPs) that might be implicated in the change of the DLX6 gene expression. The genomic DNA was collected from the venous blood of 147 male controls and 179 male patients with ASD. The genotypes of the selected SNPs were determined using the Illumina GoldenGate assay, and the statistical analyses were performed using HapAnalyzer software and SAS Enterprise. Results ： We found no association of the three SNPs in the DLX6 gene with ASD in the Korean male population. Conclusion ： Our study suggests that the three SNPs in the DLX6 gene are not associated with ASD, and we need to analyze the previously reported regions for their associations with ASD.

• 동의생리병리학회지
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• 제25권5호
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• pp.799-806
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• 2011

This study was performed in order to evaluate the neuroprotective effect of Boyanghwano-tang (BYT) water extract on intracerebral hemorrhage (ICH). ICH was induced by the stereotaxic intrastriatal injection of bacterial collagenase type IV in Sprague-Dawley rats. BYT was orally given once a day for 3 days after ICH. Hematoma volume and percentage edema were examined. As imflammatory markers, myeloperoxidase (MPO)-positive neutrophils infiltration and iNOS expression in the peri-ICH regions were examined using immunohistochemistry. As cellular damage markers, c-Fos, Bax, and HSP72 positive cells in the peri-ICH regions were measured also. BYT significantly reduced the hematoma volume and percentage edema of the ICH-induced rat brain. In the peri-hematoma regions, BYT significantly reduced MPO-positive neutrophil infiltration and iNOS expression of the ICH-induced rat brain. Additionally, BYT significantly reduced c-Fos, Bax, and HSP72 positive cells in the peri-hematoma regions of the ICH-induced rat brain. These results suggest that BYT plays a neuroprotective role against ICH through suppression of inflammatory responses, apoptosis and cellular damage.

• 한국자동차공학회논문집
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• 제21권3호
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• pp.157-164
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• 2013

A damper clutch in automatic transmission systems has some advantages of fuel economy and dynamic performance. Although a damper clutch operation improves a fuel economy of the vehicles, a positive operation of a damper clutch in a low vehicle speed induces abnormal vibration. This paper analyzed one of reasons for abnormal vibration by a damper clutch operation in low engine speed ranges. A simulation model was designed to confirm the effects of a damper clutch operation under unstable regions of an engine. A theoretical analysis was carried out about an engine operation stability. Simulation was conducted to depict abnormal vibration by a damper clutch operation in unstable regions of an engine performance curve. The effects of an engine operation region for abnormal vibration by a damper clutch was investigated according to the range and the slope of unstable regions. As a result of simulations, a damper clutch operation would be better to avoid an engine unstable regions.

• Journal of Animal Science and Technology
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• 제65권1호
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• pp.57-68
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• 2023

Flavor is an important sensory trait of chicken meat. The free amino acid (FAA) and nucleotide (NT) components of meat are major factors affecting meat flavor during the cooking process. As a genetic approach to improve meat flavor, we performed a genome-wide association study (GWAS) to identify the potential candidate genes related to the FAA and NT components of chicken breast meat. Measurements of FAA and NT components were recorded at the age of 10 weeks from 764 and 767 birds, respectively, using a White leghorn and Yeonsan ogye crossbred F2 chicken population. For genotyping, we used 60K Illumina single-nucleotide polymorphism (SNP) chips. We found a total of nine significant SNPs for five FAA traits (arginine, glycine, lysine, threonine content, and the essential FAAs and one NT trait (inosine content), and six significant genomic regions were identified, including three regions shared among the essential FAAs, arginine, and inosine content traits. A list of potential candidate genes in significant genomic regions was detected, including the KCNRG, KCNIP4, HOXA3, THSD7B, and MMUT genes. The essential FAAs had significant gene regions the same as arginine. The genes related to arginine content were involved in nitric oxide metabolism, while the inosine content was possibly affected by insulin activity. Moreover, the threonine content could be related to methylmalonyl-CoA mutase. The genes and SNPs identified in this study might be useful markers in chicken selection and breeding for chicken meat flavor.

• Clinical and Experimental Pediatrics
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• 제64권8호
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• pp.373-383
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• 2021

Rhinitis is among the most common respiratory diseases in children. Nonallergic rhinitis, which involves nasal symptoms without evidence of systemic allergic inflammation or infection, is a heterogeneous entity with diverse manifestations and intensities. Nonallergic rhinitis accounts for 16%-89% of the chronic rhinitis cases, affecting 1%-50% (median 10%) of the total pediatric population. The clinical course of nonallergic rhinitis is generally rather mild and less likely to be associated with allergic comorbidities than allergic rhinitis. Here, we aimed to estimate the rate of coexisting comorbidities of nonallergic rhinitis. Nonallergic rhinitis is more prevalent during the first 2 years of life; however, its underestimation for children with atopic tendencies is likely due to low positive rates of specific allergic tests during early childhood. Local allergic rhinitis is a recently noted phenotype with rates similar to those in adults (median, 44%; range, 4%-67%), among patients previously diagnosed with nonallergic rhinitis. Idiopathic rhinitis, a subtype of nonallergic rhinitis, has been poorly studied in children, and its rates are known to be lower than those in adults. The prevalence of nonallergic rhinitis with eosinophilia syndrome is even lower. A correlation between nonallergic rhinitis and pollution has been suggested owing to the recent increase in nonallergic rhinitis rates in highly developing regions such as some Asian countries, but many aspects remain unknown. Conventional treatments include antihistamines, intranasal corticosteroids, and recent treatments include combination of intranasal corticosteroids with azelastin or decongestants. Here we review the prevalence, diagnosis, comorbidities, and treatment recommendations for nonallergic rhinitis versus allergic rhinitis in children.

• 생명과학회지
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• 제18권12호
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• pp.1712-1717
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• 2008

국내 주요 양파 생산지인 전남 무안, 전북 부안, 경북 안동 및 경남 창녕의 3개 지역(유어, 장마, 성산)에서 수거된 양파 6종을 $0.5^{\circ}C$에 저장하면서의 휘발성 향기성분을 분석 비교하였다. 동정된 총 45종의 화합물에서 함황화합물류(21종)이 가장 많았고, 양적으로도 $66.9{\sim}86.9%$를 차지하였다(저장 0일경). 함량면에서는 유어(7,582.4 ng/g)가 가장 많았고, 다음으로 성산(5,933.3 ng/g), 무안(4,043.5 ng/g), 장마(2,374.7 ng/g), 부안(2,233.3 ng/g) 및 안동( 1,516.7 ng/g) 순이었다. 저장 60일경에는 지역에 관계없이 상당량 감소하였으며, 무안(2,445.0 ng/g), 유어(2,401.7 ng/g), 성산(1,536.4 ng/g), 안동(1,306.5 ng/g), 장마(1,188.2 ng/g) 및 부안(1,183.5 ng/g) 순이었다 항산화효과가 있는 6종의 함황화합물류(2,4-,2,5-dimetylthiophene, 2-vinyl-1,3,-dithiane, 5-methoxy thiazole, 3,5-diethyl-1,2,4-trithiolane 및 isomer)는 저장 0일경에는 유어, 성산, 무안순으로 많았으나, 저장 60일경에는 유어, 무안, 성산, 안동, 장마, 부안의 순이었다. 항암효과가 있는 함황화합물류 5종((Z)-, (E)-methyl propenyl disulfide, (Z)-, (E)-propenyl propyl disulfide, di-2-propenyl disulfide)은 저장0일에는 유어, 성산 및 무안이 가장 높았으나, 저장 60일 경에는 무안, 유어, 성산, 부안 및 장마 순이었다.

• The Plant Pathology Journal
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• 제22권1호
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• pp.1-6
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• 2006

The population shifts of Monilinia fructicola isolates which were resistant to the fungicide benzimidazoles were investigated in four regions of Korea from 1998 to 2000. The isolation frequency of benzimidazole-resistant isolates ranged from 18.8% to 29.6% in Chongdo and from $22.0\%$ to $26.8\%$ in Gyeongsan during the same period. However, the frequency of benzimidazoleresistant isolates was less than $4.0\%$ in Chochiwon and Youngduk during the same period. Benzimidazoleresistant isolates showed cross-resistance among benzimidazoles. On the other hand, none of the isolates showed cross-resistance to diethofencarb and carbendazim. Regardless of the year, the benzimidazole-resistant isolates of $EC_{50}$ higher than 500 $\mug%$ a.i./ml were isolated more frequently in mid and late season than in early season. In an orchard of Gyeongsan that had not been exposed to any fungicides for several years, the population of benzimidazole-resistant isolate had persisted without much fluctuation for three years. These results suggest that benzimidazole resistance of M. fructicola is becoming a problem in controlling brown rot and blossom blight of peach in regions like Chongdo and Gyeongsan.

• 약학회지
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• 제50권2호
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• pp.93-98
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• 2006

Human foamy virus (HFV) integrase mediates integration of viral c-DNA into cellular DNA. In this process, HFV prointegration complex (PIC) in which integrase is a key component moves to nuclei of the infected cells and leads to integration of viral DNA to the cellular genome, which is essential in viral life cycle. In general nuclear localization signals (NLS) have been suggested to be involved in localizing retroviral PIC to nuclei, but the mechanisms for nuclear localization of the HFV PIC remains unclear. To functionally identify the NLS of HFV integrase, various subdomains of the protein were expressed as GFP fusions and their subcellular locations were analyzed with confocal laser scanning microscopy. Wild type HFV integrase was karyophilic by targeting the fusion protein to nuclei of the COS-1 and 293T cells. Our results showed that strong NLS of HFV integrase was mapped to the C-terminal regions. In addition the karyophilic properties of N-terminal and central regions are not individually strong enough to direct localization of the fusion proteins to nuclei, but their cooperative activity for nuclear import was confirmed.