• Journal of Korean Neurosurgical Society
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• 제65권1호
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• pp.151-160
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• 2022

Continuous monitoring of intracranial pressure is a well established medical procedure. Still, little is known about long-term behavior of intracranial pressure in normal pressure hydrocephalus. The present study is designed to evaluate periodicity of intracranial pressure over long-time scales using intraventricular pressure monitoring in patients with normal pressure hydrocephalus. In addition, the circadian and diurnal patterns of blood pressure and body temperature in those patients are studied. Four patients, selected with "probable" normal pressure hydrocephalus, were monitored for several dozen hours. Intracranial pressure, blood pressure, and body temperature were recorded hourly. Autocorrelation functions were calculated and cross-correlation analysis were carried out to study all the time-series data. Autocorrelation results show that intracranial pressure, blood pressure, and body temperature values follow bimodal (positive and negative) curves over a day. The cross-correlation functions demonstrate causal relationships between intracranial pressure, blood pressure, and body temperature. The results show that long-term fluctuations in intracranial pressure exhibit cyclical patterns with periods of about 24 hours. Continuous intracranial pressure recording in "probable" normal pressure hydrocephalus patients reveals circadian fluctuations not related to the day and night cycle. These fluctuations are causally related to changes in blood pressure and body temperature. The present study reveals the complete loss of the diurnal blood pressure and body temperature rhythmicities in patients with "probable" normal pressure hydrocephalus.

• 한국지역지리학회지
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• 제11권4호
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• pp.429-439
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• 2005

본 연구는 한국에 있어서 동계한발의 지역적 출현빈도 분포특성과 한발시 해면기압장 및 500hPa면의 종관기후학적 특성을 평년과 비교 분석한 연구이다. 한국의 동계한발의 출현빈도 분포는 월별 지역적 강수변동률의 분포를 반영하여 1 12월은 강수변동률이 높은 한국의 동부가 높고 강수변동률이 낮은 서부가 낮아서 동고 서저유형, 2월은 북고 남저유형을 나타내고 있다. 해면기압 및 500hPa면 고도편차 분포에서 1, 2월의 한발시 한반도 주변 및 시베리아 고기압 지역은 양의 편차, 알류샨 저기압 지역 및 북태평양 서안은 음의 편차를 나타내므로 서고 동저형의 기압배치가 탁월하여 남동쪽으로부터 온난습윤한 공기의 유입이 차단될 때 한발이 출현한다. 따라서 이 때 한반도 주변은 동서풍의 풍속은 강하다. 12월의 한발 시에는 한반도를 포함한 동아시아의 중위도 전역이 양의 편차를 나타내어 남쪽으로부터 온난습윤한 공기의 유입이 적을 뿐만 아니라 저기압 통과의 빈도가 적음을 반영하고 있다.

• 한국발생생물학회지:발생과생식
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• 제23권4호
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• pp.313-322
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• 2019

The epididymal fat pad is a male gonadal adipocyte tissue and is histochemically separated into distal and proximal parts. The development of epididymal fat during postnatal period has not been examined in detail. A previous research showed that expression of adipocyte-associated molecules in the distal epididymal fat of mouse is generally increased as postnatally aged. In the present study, expressional patterns of same adipocyte-associated molecules in the mouse proximal epididymal fat at 2, 5, 8, and 12 months of age were studied by quantitative real-time PCR analysis and were compared with those in the distal epididymal fat. The expressional levels of peroxisome proliferator-activated receptor gamma (Pparg), lipoprotein lipase (Lpl), and fatty acid synthase (Fasn) at 5 months of age were significantly lower than those at 2 months of age, while transcript level of leptin (Lep) at 5 months was higher than that at 2 months of age. The transcript levels of all molecules at 8 months of age were significantly increased, compared with those at 2 and 5 months of age. At 12 months of age, expression of delta like non-canonical Notch ligand 1 (Dlk1) was further significantly increased, while there was no change on the transcript level of Pparg and significant decreases of Fabp4, Retn, Lpl, Lep, Fasn, and adiponectin (Adipoq) transcript levels. The current findings show that expressional patterns of molecules associated with adipocyte in the proximal epididymal fat is somewhat different with those of the distal epididymal fat, suggesting the existence of regional variance in the epididymal fat.

• 한국경제지리학회지
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• 제8권1호
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• pp.17-29
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• 2005

본 연구는 공간적 자기상관(spatial autocorrelation) 정도를 측정하는 공간통계 기법인 MORAN I를 사용하여 산업집적의 공간적 패턴과 구조를 분석하였다. 분석결과 우리나라는 수도권 이외 지역의 혁신환경이 열악한 가운데 주요 산업집적지가 수도권 일대와 동남권 일대를 중심으로 분포하고 있는 다핵형 공간구조를 형성하고 있다. 그리고 일부 산업의 경우 산업집적지는 광역 시 $\cdot$ 도 단위의 행정구역을 넘어서는 집적패턴이 나타나고 있다. 이에 따라 본 연구는 한국경제발전을 위한 최우선 과제의 하나가 산업집적과 혁신환경의 공간적 불일치라는 경제 공간구조를 조정하는 것이어야 하며, 이를 위해서는 16개 광역 시 $\cdot$ 도 보다는 인접한 2$\∼$3개 광역 시 $\cdot$ 도를 포괄하는 경제권역을 단위로 산업클러스터 기반의 지역혁신체제 구축이 필요함을 제시하였다.

• Ocean and Polar Research
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• 제34권4호
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• pp.431-444
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• 2012

We simulated and compared present and future ocean circulation in the East China Sea using an East Asia Regional Ocean model. Mean climate states for 1990~1999 and 2030~2039 were used as surface conditions for simulations of present and future ocean circulation, which were derived from the simulations of three different global climate models, ECHAM5-MPI, GFDL-CM2.0 and MIROC3.2_hires, for the 20th century and those of 21st century as projected by the IPCC SRES A1B. East Asia Regional Ocean model simulated the detailed patterns of temperature, salinity and current fields under present and future climate conditions and their changes instead of the simple structures of global climate models. To some extent, there are consistent ocean circulation changes derived from the three pairs corresponding to the global climate model in so much as the temperature increases not only in winter but summer at both the surface and bottom and that temperature and salinity changes are prominent near the Chinese coast and in the Changjiang bank. However, the simulated circulations are different among each other depending on the prescribed atmospheric conditions not only under present climate but also with regard to future climate conditions. There is not a coincident tendency in ocean circulation changes between present and future simulations derived from the three pairs. This suggests that more simulations with different pairs are needed.

• 한국대기환경학회지
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• 제28권6호
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• pp.615-631
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• 2012

This study provides an evaluation for capability of Integrated Climate and Air quality Modeling System (ICAMS) on future regional scale climate projection. Temperature and precipitation are compared between ground-level observation data and results of regional models (MM5) for the past 30 years over the Korean peninsula. The ICAMS successfully simulates the local-scale spatial/seasonal variation of the temperature and precipitation. The probability distribution of simulated daily mean and minimum temperature agree well with the observed patterns and trends, although mean temperature shows a little cold bias about $1^{\circ}C$ compared to observations. It seems that a systematic cold bias is mostly due to an underestimation of maximum temperature. In the case of precipitation, the rainfall in winter and light rainfall are remarkably simulated well, but summer precipitation is underestimated in the heavy rainfall phenomena of exceeding 20 mm/day. The ICAMS shows a tendency to overestimate the number of washout days about 7%. Those results of this study indicate that the performance of ICAMS is reasonable regarding to air quality predication over the Korean peninsula.

• 대한지리학회지
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• 제41권1호
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• pp.58-72
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• 2006

현대 경제는 첨단 산업의 발달로 연구개발 활동의 중요성이 더욱 부각되고 있다. 이에 본 연구는 우리나라의 기업 연구개발 활동의 공간적 분포 특징을 파악하고자 거시적으로 접근하였다. 분석 결과, 우리나라 기업부설연구소는 수도권 지역에서 높은 집중현상을 나타냈으나, 세부 분석에서 연구소들은 업종에 따라 상이한 입지 경향을 보였으며, 첨단산업의 성격이 낮을수록 연구소의 수도권 집중 현상은 낮아지는 것으로 나타났다. 또한 기업의 규모가 클수록, 고급 연구 인력 확보 수준이 높을수록 연구소의 입지는 분산되는 경향을 보였다. 이외에도 기업부설연구소들은 본사나 공장과 한 장소에 입지하거나 같은 업종의 연구소들과 한 장소에 입지하는 경향이 있으며, 이러한 입지 행태는 지역적으로 다르게 나타났다. 이러한 특징들을 종합하여 본 연구에서는 연구소의 입지 유형을 4가지로 분류하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2015년도 학술발표회
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• pp.229-229
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• 2015

Downscaling is a fundamental procedure in the assessment of the future climate change impact at regional and watershed scales. Hence, it is important to investigate the spatial variability of the climate conditions that are constructed by various downscaling methods in order to assess whether each method can model the climate conditions at various spatial scales properly. This study introduces a fundamental research from Jang and Kavvas(2015) that precipitation variability from a popular statistical downscaling method (BCSD) and a dynamical downscaling method (MM5) that is based on the NCAR/NCEP reanalysis data for a historical period and on the CCSM3 GCM A1B emission scenario simulations for a projection period, is investigated by means of some spatial characteristics: a) the normalized standard deviation (NSD), and b) the precipitation change over Northern California region. From the results of this study it is found that the BCSD method has limitations in projecting future precipitation values since the BCSD-projected precipitation, being based on the interpolated change factors from GCM projected precipitation, does not consider the interactions between GCM outputs and local geomorphological characteristics such as orographic effects and land use/cover patterns. As such, it is not clear whether the popular BCSD method is suitable for the assessment of the impact of future climate change at regional, watershed and local scales as the future climate will evolve in time and space as a nonlinear system with land-atmosphere feedbacks. However, it is noted that in this study only the BCSD procedure for the statistical downscaling method has been investigated, and the results by other statistical downscaling methods might be different.

• 한국작물학회지
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• 제45권4호
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• pp.267-271
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• 2000

A total of 1,830 soybean collections were grown in the field and characterized for 10 morphological traits to determine the diversity and relationship within and among geographical regions. Phenotypic variation was found within all regions for most characters. The Shannon-Weaver diversity index ranged from 0.49 to 0.62 across regions, and 0.09 to 1.00 across characters. Canonical discriminant analysis and clustering of the canonical means delineated 3 regional clusters: (ⅰ) Kyunggi, Chungchong, Kangwon, Chulla, and Kyungsang; (ⅱ) Heilongjiang; and (ⅲ) Jilin, Manchuria, central China, south China, Others (China), Hokkaido, Honshu, and Others (Japan).

• KDI Journal of Economic Policy
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• 제42권3호
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• pp.1-32
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• 2020

This paper studies urban growth in Korean cities. First, I document that population growth patterns change over time and that the current population distribution supports random urban growth. I confirm two empirical laws-Zipf's law and Gibrat's law-both of which hold in the period of 1995-2015, but do not hold in the earlier period of 1975-1995. Second, I find a systematic employment growth pattern of Korean cities in spite of the random population growth. I examine market access effects on employment growth. Market access, a geographical advantage, has a significant influence on urban employment growth. The market access effect is higher in the Seoul metropolitan area than in the rest of the country. This effect is stronger on employment growth in the manufacturing industry compared to employment growth in the service industry. These results are robust with various checks (e.g., different definitions of urban areas). The results here suggest that policymakers should consider geographical characteristics when they make policy decisions with respect to regional development.