• Archives of design research
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• v.15 no.1
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• pp.59-67
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• 2002

In accordance with the fast changing circumstance, universities are now reaching, beyond the education place of simple delivery of knowledge and exchange of information, to a place of developing a specialty program related with the region and industry to achieve a competitive edge in education. Through these academic-industrial collaboration program, special knowledge and human resources in the university are utilized in the society and it may contribute to the development of industry and breed of career people based upon the real job site can be achieved. In addition, through the practical operation of such developed program, university may contribute to the enhancement of the competitiveness of the corporation to the activation and acceleration of the regional economy and finally to the enhancement of competitiveness of national industry in international level. This study tries to develop 3 technical instruction and support program related with the legion and industry which may conform to the ideals of university and its goal of education and can provide a platform for the education that is closely related with the regional industry and real job site iud may cope actively with the upcoming knowledge society and fast changing regional circumstances. This study will make research and analyze needs of design support from the industry in order to develop a academic-industrial cooperative design support program for the furniture industry which conforms to the regional characteristic and feature and develop and present contents of program in three area of development of furniture design technology, build-up of furniture design information system and establishment of order based education system. The proposed program is supposed to be operated practically and effectively and contribute to the development of new product, to enhancement of company image and finally to the maximization of corporate profit. Also this study is epected to be used as an important material for establishment of order-based education system which confirms to the job site needs that may be analysed from feedback of product results and for practical learning.

• Archives of Plastic Surgery
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• v.33 no.3
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• pp.324-329
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• 2006

The silicone rubber implants are widely used in plastic surgery because of various advantages; however, calcification in surface of implant(as a chemical resistance) may transform or destroy the high molecular biomaterial when it stays too long within the human body. The purpose of this study is to determine the relationship between calcification and the histological disparities of the tissues surrounding the area adjoining the silicone nasal implant by examining the regional characteristics of calcium deposits in the silicone nasal implant via elemental analyses using EDX(energy-dispersive X-ray analysis) and ultrastructural analyses using SEM(scanning electron microscopy). The subjects of the study were 19 silicone nasal implants removed by revision rhinoplasty, all displaying calcification. According to the tissue characters, the implant surface was divided into 4 zones with the rhinion as the basis. For each zone, elemental and ultrastructural analyses were performed. Elemental analysis revealed that the calcium deposits consisted of Ca and P only. There were no statistically significant disparities among the ratios between Ca and P according to the zones. Ultrastructural analysis showed acellular mineral-like deposits coalesced to create amorphous deposits in all zones; however, in zones 1 and 3(more pressurized zones by periosteum or nasal bone), additional flaky cylinder-shaped calcium deposits were detected. Thus, it seems that the histological disparities in the surrounding tissues do not affect the components and their proportions in the calcification process. However, it can be inferred that the physical environment due to the histological disparities in the surrounding tissues affects the ultrastructures of calcium deposits.

• Archives of Plastic Surgery
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• v.37 no.1
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• pp.71-74
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• 2010

Purpose: Nowadays spinal cord stimulator is frequently used for the patients diagnosed as complex regional pain syndrome. The lead is placed above the spinal cord and connected to the stimulation generator, which is mostly placed in the subcutaneous layer of the abdomen. When the complication occurs in the generator inserted site, such as infection or generator exposure, replacement of the new generator to another site or pocket of the abdomen would be the classical choice. The objective of our study is to present our experience of the effective replacement of the existing stimulation generator from subcutaneous layer to another layer in same site after the wound infection at inexpensive cost and avoidance of new scar formation. Methods: A 50-year-old man who was diagnosed as complex regional pain syndrome after traffic accident received spinal cord stimulator, Synergy$^{(R)}$ (Medtronic, Minneapolis, USA) insertion 1 month ago by anesthetist. The patient was referred to our department for wound infection management. The patient was presented with erythema, swelling, thick discharge and wound disruption in the left upper quadrant of the abdomen. After surgical debridement of the capsule, the existing generator replacement beneath the anterior layer of rectus sheath was performed after sterilization by alcohol. Results: Patient's postoperative course was uneventful without any complication and had no evidence of infection for 3 months follow-up period. Conclusion: Replacement of existing spinal cord stimulation generator after sterilization between the anterior layer of rectus sheath and rectus abdominis muscle in the abdomen will be an alternative treatment in wound infection of stimulator generator.

• Archives of Pharmacal Research
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• v.28 no.11
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• pp.1270-1274
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• 2005

The vascular endothelial growth factor (VEGF) plays a key role in angiogenesis, which is a process where new blood vessels develop from the endothelium of a pre-existing vasculature. VEGF exerts its activity by binding to its receptor tyrosine kinase, KDR/Flk-1, which is expressed on the surface of endothelial cells. A methanol extract and organic solvent (n-hexane, ethyl acetate, n-butanol, aqueous) fractions from Rubus coreanus were examined for their inhibitory effects on VEGF binding to the VEGF receptor. The methanol extract from the crude drug were found to significantly inhibit VEGF binding to the VEGF receptor ($IC_{50}$$\thickapprox$27 $\mu$g/mL). Among the fractions examined, the aqueous fraction from the medicinal plant showed potent inhibitory effects against the binding of KDR/Flk-1-Fc to immobilized $VEGF_{165}$ in a dose­dependent manner ($IC_{50}$$\thickapprox$11 $\mu$g/mL). Sanguiin H-6 was isolated as an active principle from the aqueous fraction, and inhibited the binding of KDR/Flk-1-Fc to immobilized $VEGF_{165}$ in a dose­dependent manner ($IC_{50}$$\thickapprox$0.3 $\mu$g/mL). In addition, sanguiin H-6 efficiently blocked the VEGF­induced HUVEC proliferation in a dose-dependent manner ($IC_{50}$$\thickapprox$7.4 $\mu$g/mL) but had no effect on the growth of HT1080 human fibrosarcoma cells. This suggests that sanguiin H-6 might be a potential anti-angiogenic agent.

• Journal of the Korean association of regional geographers
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• v.21 no.1
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• pp.153-175
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• 2015

This study is to analyse Korean map inserted in the "Gwandong Gwanseo-jido(關東 關西地圖)" which is reserved in the Gyujanggak Archives as the mother edition of Korean Map("朝鮮圖") in Kangxi Atlas made in Qing dynasty. Map in Gyujanggak is very similar to the Korean map in the Kangxi atlas in terms of shape of southern part of Korean peninsula, boundary of provinces. Especially over 80% of place names on two maps are coincident and over 90% of islands names are identical. It is revealed that map in the Gyujanggak Archive is the most similar map to the Kangxi Atlas in Korea. This map was produced in 1729~1736 which is late compared to the Kangxi Atlas. This difference of production period shows that mother editon of map in Gyujanggak is the base map of Korean Map in Kangxi atlas. The similarity and differences between those maps show the process of edition of geography in the produce the Kangxi atlas. And map in Gyujanggak shows that production of new type of Korean whole map was began in the late $17^{th}$ century.

• Archives of design research
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• v.18 no.3 s.61
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• pp.25-34
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• 2005

Local governments have been actively introducing the characters, which identity their regional features and publicize the governments, to increase municipal identity and encourage the participation of residents since the self-governing system was enforced in 1996. Some characters of local governments, however, were not often developed systematically and did not perform the intended purposes. This study reviewed general theories related to the general and municipal characters. Currently employed municipal characters were analyzed in various perspectives : problems of the characters were presented mixed use of terms for the symbol, selection of not creative materials. In addition, unsystematic planing and indifference of residents were revealed. This study could be utilized to shape design policy and applied to develop the municipal characters illustrating the proper regional characteristics and performing practical function.

• Archives of Hand and Microsurgery
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• v.23 no.4
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• pp.296-300
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• 2018

Penile shaft reconstruction requires adequate soft tissue characteristics as well as constant vascular pedicles when considering a perforator flap. The free flap technique using various donor sites and regional conventional and perforator flaps have been utilized for penile shaft reconstruction. Still, the free flap techniques include challenging surgical procedures in addition to postoperative management. The regional flap can be applied to limited defects due to the size and shape. We performed the bilateral superficial external pudendal artery (SEPA) perforator flaps in order to reconstruct a circumferential penile shaft defect. The circumferential wound has noted necrotic tissue involving superficial (Dartos) fascia. We underwent debridement, preserving deep (Buck's) fascia and corpus spongiosum. Thereafter, the soft tissue defect was covered with bilateral SEPA perforator flaps. The patient has been observed for 27 months, showing penile resilience without deformity or wound-related problems.

• Archives of Plastic Surgery
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• v.44 no.3
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• pp.238-242
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• 2017

The most common anatomic variant seen in donor kidneys for renal transplantation is the presence of multiple renal arteries, which can cause an increased risk of complications. Accessory renal arteries should be anastomosed to the proper source arteries to improve renal perfusion via the appropriate vascular reconstruction techniques. In microsurgery, 2 kinds of vascular augmentation methods, known as 'supercharging' and 'turbocharging,' have been introduced to ensure vascular perfusion in the transferred flap. Supercharging uses a distant source of the vessels, while turbocharging uses vascular sources within the same flap territory. These technical concepts can also be applied in renal transplantation, and in this report, we describe 2 patients who underwent procedures using supercharging and turbocharging. In one case, the ipsilateral deep inferior epigastric artery was transposed to the accessory renal artery (supercharging), and in the other case, the accessory renal artery was anastomosed to the corresponding main renal artery with a vascular graft (turbocharging). The transplanted kidneys showed good perfusion and proper function. No cases of renal failure, hypertension, rejection, or urologic complications were observed. These microsurgical techniques can be safely utilized for renal transplantation with donor kidneys that have multiple arteries with a lower complication rate and better outcome.

• Archives of Plastic Surgery
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• v.43 no.6
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• pp.586-589
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• 2016

A pressure sore wound is often extensive or complicated by local infection involving adjacent soft tissue and bone. In this case, a regional flap after simple debridement is not adequate. Here, we present a case of an extensive pressure sore in the sacral area with deep tissue infection. A 43-year-old female patient with a complicated sore with deep tissue infection had a presacral abscess, an iliopsoas abscess, and an epidural abscess in the lumbar spine. After a multidisciplinary approach performed in stages, the infection had subsided and removal of the devitalized tissue was possible. The large soft tissue defect with significant depth was reconstructed with a free latissimus dorsi musculocutaneous flap, which was expected to act as a local barrier from vertical infection and provide tensionless skin coverage upon hip flexion. The extensive sacral sore was treated effectively without complication, and the deep tissue infection completely resolved. There was no evidence of donor site morbidity, and wheelchair ambulation was possible by a month after surgery.

• Archives of design research
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• no.18
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• pp.99-110
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• 1996

For the purpose of sped fying the character of Italian furniture industry, it's very important to analyse environmental aspects, in other word s, infrastructure of the furniture industry. These conditions that regional si tuation and circumstances, small and medium size of company depending upon the fami Iy oriented craftsman ship, roles of producers who are very keen on technical innovation and improvement, distribu tion structure and production status etc, are important factors to understand environmental characters of the furniture industry. Moreover, existence of various design languges according to design activities by architects un der that industrial structure is also regarded as the characters of that furniture industry. Through understanding the characters of Italian furniture industry and the drivig force of the growth, I would I ike to propose a role model for our domestic furniture industry.