• Title/Summary/Keyword: regenerative material

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Polymer brush: a promising grafting approach to scaffolds for tissue engineering

  • Kim, Woonjung;Jung, Jongjin
    • BMB Reports
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    • v.49 no.12
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    • pp.655-661
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    • 2016
  • Polymer brush is a soft material unit tethered covalently on the surface of scaffolds. It can induce functional and structural modification of a substrate's properties. Such surface coating approach has attracted special attentions in the fields of stem cell biology, tissue engineering, and regenerative medicine due to facile fabrication, usability of various polymers, extracellular matrix (ECM)-like structural features, and in vivo stability. Here, we summarized polymer brush-based grafting approaches comparing self-assembled monolayer (SAM)-based coating method, in addition to physico-chemical characterization techniques for surfaces such as wettability, stiffness/elasticity, roughness, and chemical composition that can affect cell adhesion, differentiation, and proliferation. We also reviewed recent advancements in cell biological applications of polymer brushes by focusing on stem cell differentiation and 3D supports/implants for tissue formation. Understanding cell behaviors on polymer brushes in the scale of nanometer length can contribute to systematic understandings of cellular responses at the interface of polymers and scaffolds and their simultaneous effects on cell behaviors for promising platform designs.

Low Carbon operation study through comparing GHG contribution of each stages of railway vehicle (철도차량 전과정 단계별 온실가스 발생량 비교를 통한 저탄소 운영방안 연구)

  • Lee, Cheul-Kyu;Kim, Yong-Ki
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.183-186
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    • 2010
  • Advanced Railway countries are developing technologies of production and management for low-carbon and green growth of their railway industry to hold a dominant position under post-Tokyo protocol regime through integrated approach which uses environmental quantitative analysis of train life cycle by using LCA(Life Cycle Assessment). On the contrary, Korea railroad industry attempts to make an environmental improvement only for using regenerative energy and improvement in operating energy consumption through adapting reduction weight of material technology and etc. without systematic environmental analysis approaches such as comparing and analyzing energy consumption as well as GHG emission in each life cycle stages of train. Therefore, In this paper, low-carbon management and comprehensive environmental improvement for sustainable development of Korea railway industry through analyzing the result of life cycle analysis in abroad are suggested.

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First Finding of a Bivalve-Inhabiting Hydrozoan (Cnidaria, Hydrozoa) from Korea

  • Kubota, Shin;Lee, Jimin;Chang, Cheon Young
    • Animal Systematics, Evolution and Diversity
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    • v.35 no.2
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    • pp.57-62
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    • 2019
  • Eutima japonica Uchida, 1925, a bivalve-inhabiting hydrozoan was collected for the first time in Korea, associating with Mytilus galloprovincialis. The morphology of male medusae of this hydrozoan is clarified by culture and described as well as other developmental stages. As the present material from Korea is in good accord with that of the northern Japanese form of E. japonica, so the geographical distribution of the northern form of this species is widened, Japan, China and Korea. Green fluorescent protein distribution pattern of this medusa is also described and compared with that of the most related species Eutima sapinhoa Narchi and Hebling, 1975.

Radiographic evaluation of infra-bony defects treated by bone graft procedures (골 이식술에 의해 치료된 골연하 결손부의 방사선학적 변화 양상의 관찰)

  • Ryu, Sang-Ho;Park, Jin-Woo;Suh, Jo-Young;Lee, Jae-Mok
    • Journal of Periodontal and Implant Science
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    • v.38 no.3
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    • pp.437-444
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    • 2008
  • Purpose: A number of techniques and materials have been used for periodontal regeneration and bone graft procedures with guided tissue regeneration(GTR) have been suggested as alternatives to osseous surgery in the management of local infra-bony defects. However, the long-term stability and treatment outcome following bone graft procedure of infra-bony defects is poorly documented. The purpose of this study was to assess radiographic change in infra-bony defects over 2 years after bone graft procedures with various graft materials. Material and Methods: Patients attending the department of periodontics of Kyungpook National University Hospital were studied. Patients showed clinical and radiographic evidence of infra-bony defect(s). 44 sites of 34 patients aged 31 to 69 (mean age 48.3) were treated by bone graft procedure with a bone graft material. Baseline and 2-year follow-up radiographs were collected and evaluated for this study. Radiographic assessment includes a bone fill, bone crest change, defect resolution, and % of defect resolution. Pre- and post-treatment differences between variables (maxilla and mandible, defect depth, defect angle, bone graft materials) using the paired t-test were examined. Result: We observed $1.15{\pm}1.95\;mm$ of bone fill, $0.40{\pm}1.19\;mm$ of crestal resorption, $1.55{\pm}1.77\;mm$ of defect resolution, and $40{\pm}44%$ of percentage of defect resolution. Deeper initial defect depth, narrower initial defect angle showed significantly greater bone fill, defect resolution, and % of defect resolution. But no significant difference was observed in graft sites and graft materials. Conclusion: If good oral hygiene maintenance and periodic recall check of patients is assured, bone graft procedure using various graft materials is one of the appropriate treatment modality for regenerative therapy of infra-bony defects.

Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison

  • Oltra, Enrique;Cox, Timothy C.;LaCourse, Matthew R.;Johnson, James D.;Paranjpe, Avina
    • Restorative Dentistry and Endodontics
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    • v.42 no.1
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    • pp.19-26
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    • 2017
  • Objectives: Recently, bioceramic sealers like EndoSequence BC Sealer (BC Sealer) have been introduced and are being used in endodontic practice. However, this sealer has limited research related to its retreatability. Hence, the aim of this study was to evaluate the retreatability of two sealers, BC Sealer as compared with AH Plus using micro-computed tomographic (micro-CT) analysis. Materials and Methods: Fifty-six extracted human maxillary incisors were instrumented and randomly divided into 4 groups of 14 teeth: 1A, gutta-percha, AH Plus retreated with chloroform; 1B, gutta-percha, AH Plus retreated without chloroform; 2A, gutta-percha, EndoSequence BC Sealer retreated with chloroform; 2B, gutta-percha, EndoSequence BC Sealer retreated without chloroform. Micro-CT scans were taken before and after obturation and retreatment and analyzed for the volume of residual material. The specimens were longitudinally sectioned and digitized images were taken with the dental operating microscope. Data was analyzed using an ANOVA and a post-hoc Tukey test. Fisher exact tests were performed to analyze the ability to regain patency. Results: There was significantly less residual root canal filling material in the AH Plus groups retreated with chloroform as compared to the others. The BC Sealer samples retreated with chloroform had better results than those retreated without chloroform. Furthermore, patency could be re-established in only 14% of teeth in the BC Sealer without chloroform group. Conclusion: The results of this study demonstrate that the BC Sealer group had significantly more residual filling material than the AH Plus group regardless of whether or not both sealers were retreated with chloroform.

Applying Hybrid Type Energy Storage System in AC High Speed Railway (하이브리드 타입 에너지 저장장치의 교류 고속철도 적용)

  • Jeon, Yong-Joo;Kang, Byoung-Wook;Chai, Hui-Seok;Kim, Jae-Chul
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.28 no.9
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    • pp.60-66
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    • 2014
  • In case of DC railway, value of ESS(Energy Storage System) is already approved. Whereas AC railway system, there are a lot of differences such as system design and operation pattern. Therefore there is doubt about AC ESS usefulness. Especially, regenerative energy can return to the source. So in case of AC 25kV system, it is necessary to consider different operation algorithm compare to DC railway system. In this paper ESS which is installed in AC high-speed railway was introduced. Power consumption pattern of High speed trains were analyzed, proper storage material was reviewed and operation algorithm was suggested. Super capacitor and Battery was used with hybrid type. Super capacitor was used to handle short term energy movement because of its prompt response and battery was used to handle long term energy movement because of its high energy density. Also in case of operation algorithm, phase control method was upgraded compare to voltage magnitude detection method.

Advances in the design of macroporous polymer scaffolds for potential applications in dentistry

  • Bencherif, Sidi A.;Braschler, Thomas M.;Renaud, Philippe
    • Journal of Periodontal and Implant Science
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    • v.43 no.6
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    • pp.251-261
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    • 2013
  • A paradigm shift is taking place in medicine and dentistry from using synthetic implants and tissue grafts to a tissue engineering approach that uses degradable porous three-dimensional (3D) material hydrogels integrated with cells and bioactive factors to regenerate tissues such as dental bone and other oral tissues. Hydrogels have been established as a biomaterial of choice for many years, as they offer diverse properties that make them ideal in regenerative medicine, including dental applications. Being highly biocompatible and similar to native extracellular matrix, hydrogels have emerged as ideal candidates in the design of 3D scaffolds for tissue regeneration and drug delivery applications. However, precise control over hydrogel properties, such as porosity, pore size, and pore interconnectivity, remains a challenge. Traditional techniques for creating conventional crosslinked polymers have demonstrated limited success in the formation of hydrogels with large pore size, thus limiting cellular infiltration, tissue ingrowth, vascularization, and matrix mineralization (in the case of bone) of tissue-engineered constructs. Emerging technologies have demonstrated the ability to control microarchitectural features in hydrogels such as the creation of large pore size, porosity, and pore interconnectivity, thus allowing the creation of engineered hydrogel scaffolds with a structure and function closely mimicking native tissues. In this review, we explore the various technologies available for the preparation of macroporous scaffolds and their potential applications.

Physical and Sensory Properties of Ice Cream Containing Fermented Pepper Powder

  • Yeon, Su-Jung;Kim, Ji-Han;Hong, Go-Eun;Park, Woojoon;Kim, Soo-Ki;Seo, Han-Geuk;Lee, Chi-Ho
    • Food Science of Animal Resources
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    • v.37 no.1
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    • pp.38-43
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    • 2017
  • This study was conducted to investigate the physical and sensory properties of ice cream containing fermented pepper powder. Three ice cream formulas were manufactured: 1, control; 2, supplemented with 0.1% fermented pepper powder; and 3, supplemented with 0.2% fermented pepper powder. Formulas 2 and 3 had significantly higher viscosity and lower overrun than formula 1 (p<0.05). Additionally, ice creams supplemented with fermented pepper powder were harder and maintained their forms longer than the controls. 0.2% fermented pepper powder added ice cream had no pungency as much as that of control and overall sensory attribute was not significantly different from control. Therefore, ice cream containing fermented pepper powder maintained physical and sensory properties similar to the controls, and maintenance was better. It means fermented pepper powder ice cream can be utilized as the material of functional food (dessert).

A Study on the Eco-Tecnique of EcoCenter - Focused on the Building Material and Solar System - (에코센터의 생태건축기술에 관한 연구 - 건축재료와 태양에너지활용시스템을 중심으로 -)

  • Choi, Young-Ho;Shim, Woo-Gab
    • KIEAE Journal
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    • v.4 no.2
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    • pp.65-72
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    • 2004
  • Ecological architecture enables people to recycle and reuse architectural resources within the category of ecosystem and also to minimize the effect on environment in a whole process, including architectural planning, usage and exhaustion to use sustainable energies. Rammed earth wall construction method utilized in EcoCenter located in Crystalwaters ecological village in Austrailia is a good example, which maximizes its advantages and also covers its limits to use soil and wood as structural resources. In a case of wood, they used non-treated timber to minimize environmental load and utilized used materials in openings. In the roofs, aluminum coated steel which is plated with zinc collects rain effectively even though it is not regenerable. Nontoxic finishes and insulation in floor and ceiling with used papers are able to minimize its environmental load. Solar energy system applied in EcoCenter enables them to market extra energy with electricity companies as well as support needs of its own buildings to utilize photovoltaic panel system with PV panels. Passive solar system is planned effectively in heating and cooling to apply regenerative walls in a use of rammed earth wall construction and natural ventilation systems through openings.