• 제목/요약/키워드: reference standards

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Meteorological basis for wind loads calculation in Croatia

  • Bajic, Alica;Peros, Bernardin
    • Wind and Structures
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    • 제8권6호
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    • pp.389-406
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    • 2005
  • The results of reference wind speed calculation in Croatia as a base for the revision of the Croatian standards for wind loads upon structures are presented. Wind speed averaged over 10 minutes, at 10 m height, in a flat, open terrain, with a 50-year mean return period is given for 27 meteorological stations in Croatia. It is shown that the greatest part of Croatia is covered with expected reference wind speeds up to 25 m/s. Exceptions are stations with specific anemometer location open to the bura wind which is accelerated due to the channelling effects of local orography and the nearby mountain passes where the expected reference wind speed ranges between 38 m/s and 55 m/s. The methodology for unifying all available information from wind measurements regardless of the averaging period is discussed by analysing wind speed variability at the meteorological station in Hvar.

Probabilistic analysis of Italian extreme winds : Reference velocity and return criterion

  • Ballio, G.;Lagomarsino, S.;Piccardo, G.;Solari, G.
    • Wind and Structures
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    • 제2권1호
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    • pp.51-68
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    • 1999
  • Applying and extending some preceding researches, this paper proposes a map of Italian extreme winds assigning the reference velocity, i.e., the wind velocity averaged over 10 minutes, at 10 m height, in a flat open terrain, with 50 years mean return period, depending on the site and the altitude. Furthermore, an objective criterion is formulated by which the actual values of the local wind velocity are given as a function of the reference velocity. The study has been carried out in view of the revision of the Italian Standards dealing with safety and loads and the introduction of the aeolic Italian map into Eurocode 1.

재조합 사람성장호르몬(소마트로핀)의 KFDA 표준품(KS 98/674) 설정 연구 (Collaborative Study for the Establishment of KFDA Reference Standard for Somatropin (KS 98/674))

  • 신원;정지원;진재호;;손여원
    • 약학회지
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    • 제45권2호
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    • pp.227-236
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    • 2001
  • The complexity and variability of both the biologicals and the bioassays used to test them led to the use of the reference standard- a sample of the product of defined purity and potency, against which all preparations of that product must be calibrated. In order to prepare and establish KFDA reference standard for recombinant human growth hormone (somatropin), somatropin substance was filled in ampoules in National Institute for Biological Standards and Control (NIBSC). The candidate KFDA reference standard for somatropin (designated as 98/674) was evaluated to determine the suitability of serving as a KFDA reference standard for somatropin by the collaborative study, in which 10 laboratories participated. Physicochemical analysis and in vivo bioassay were performed by direct comparison with the international somatropin standard 88/624. 98/674 was identified as somatropin by SDS-PAGE, IEF, peptide mapping, and HPLC. Determination of somatropin content by SE-HPLC yielded a mean estimate of 2.01 mg somatropin per ampoule. Data from the study also yielded mean values of 0.39 $\pm$ 0.26% for high molecular weight impurities by SE-HPLC and mean values of 2.13 $\pm$ 1.29% for somatropin related proteins by RP-HPLC. Estimates of relative potency by weight gain bioassay in the hypophysectomised rats showed that relative potency of KS 98/674 was 1.07 aganist IS 88/624. Based on the results of the collaborative study, the candidate reference standard for somatropin is suitable to serve as a KFDA reference standard for somatropin.

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고령자를 위한 교회 편의시설 설치기준의 중요도에 대한 주체별 인식의 간극 (Perceptive Gap among Interest Groups to Significance of the Installation Standards of Churches' Convenience Facilities for the Elderly)

  • 이종희;김덕수
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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    • 제19권1호
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    • pp.47-57
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    • 2013
  • Purpose: The purpose of this study is to provide reference points for the improvement work of churches' convenience facilities for the elderly. To do this, the study generates survey results, showing that the perception to significance of churches' convenience facilities is different among survey constituents. Method: The survey method was utilized. The study population for survey includes the aged believer over 65 years old, pastors, and architecture and/or interior design experts. The questionnaire was devised while consulting existing regulations regarding convenience facilities in general. Results: It is found that the perception to significance of installation standards for convenience facilities is different among survey constituents. Specifically, while the older believer group is perceived that installation standards for the small group meeting room of 'other facility' is comparatively more important, the pastor group and the expert group perceive that the 'intermediate facility' and 'inner facility' are more important. Implications: Participants involved in an improvement project of churches' convenience facilities may have a different perception about their importance due mainly to the degree of usage and the difference of perspectives. This study, therefore, can be used as a reference point for prioritizing improvement works of churches' convenience facilities for the elderly.

핵심국제비교용 물의 삼중점 셀 제작과 비교 실험 및 불확도 평가 (Construction and Comparison Measurement of Triple Point Water Cells for using Key Comparison and Evaluation of Uncertainty)

  • 강기훈;김용규;감기술
    • 센서학회지
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    • 제13권2호
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    • pp.114-120
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    • 2004
  • The $Comet{\acute{e}}$ Consultatif de $Thermom{\acute{e}}trie$ (CCT) under the Comete International des Poids et Measures (CIPM) has decided to perform the Key Comparison (KC) for triple point of water cells used as a reference fixed point of thermometry at the 21st meeting held at November 2001, and the Bureau International des Poids et Measures (BIPM) has been nominated as a KC coordinator. According to the KC protocol prepared by BIPM, KRISS performed the KC experiments and evaluate a uncertainty. The temperature difference between two reference cells for the Korea Research Institute of Standards and Science (KRISS) and a test cell for the transfer standard, which is moved to BIPM was 0.024 mK and the combined standard uncertainty evaluated 0.055 mK.

Development of an Isotope-Dilution Liquid Chromatography/Mass Spectrometric Method for the Accurate Determination of Acetaminophen in Tablets

  • Shin, Hyun-Ju;Kim, Byung-Joo;Lee, Joon-Hee;Hwang, Eui-Jin
    • Bulletin of the Korean Chemical Society
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    • 제31권12호
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    • pp.3663-3667
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    • 2010
  • Acetaminophen (N-acetyl-p-aminophenol) is one of the most popular analgesic and antipyretic drugs. An isotope dilution mass spectrometric method based on LC/MS was developed as a candidate reference method for the accurate determination of acetaminophen in pharmaceutical product. After spiking an isotope labeled acetaminophen (acetyl-$^{13}C_2$, $^{15}N$-acetaminophen) as an internal standard, tablet extracts were analyzed by LC/MS in a selected reaction monitoring (SRM) mode to detect ions at m/z $152{\rightarrow}110$ and m/z $155{\rightarrow}111$ for acetaminophen and acetyl-$^{13}C_2$, $^{15}N$-acetaminophen, respectively. The repeatability and reproducibility of the developed ID/LC-MS method were tested for the validation and assessment of metrological quality of the method.

모유영양아와 인공영양아의 1~3개월의 성장발육 상태 평가-한국 표준치와 NCHS Reference간의 비교- (Evaluation of Growth between Breast-Fed and Formula-Fed Korean Infants from 1 to 3 Postpartum Months -Compared with the Korean Standard and NCHS Reference-)

  • 최경숙;구재옥
    • 대한지역사회영양학회지
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    • 제3권4호
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    • pp.533-541
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    • 1998
  • This study compares the growth performance(weight-for-age Z-score, height-for-age Z-score, weight-for-height Z-score) of one- to three- month-old Korean infants(n=232) with the Korean standard(1994) and NCHS reference(1983). The weight-for-age Z-scores(WAZ) by the Korean standard were -2∼1,5 for males and -3∼1 for females. The NCHS reference, WAZ results were -1∼2.5 and -2.5∼3.5 for males and females, respectively. The WAZ compared Korean standard showed no subjects with overnutrition. But 1.3% of the infants showed signs of malnutrition. Comparison with NCHS reference revealed that 0.4% of the infants were malnourished and 7.0% of the infants were overnourished. The WAZ of formula-fed infants were distributed higher than breast-fed infants, but that was not significant. The height-for-age Z-score(HAZ) by the Korean standard were -4.5%∼1.5% for males and -4∼1.5% for females. According to the NCHS reference, HAZ were -2.5%∼2.5% and -3∼3 for males and females, respectively. When the WAZ was compared with the Korean standard, there was no overnutrition but 16% of the infants showed signs of malnutrition. The NCHS reference, revealed that 6.9% of the infants were malnourished and 1.8% of the infants were ovemourished. The weight-for-height Z-scores(WHZ) by the Korean standard were -2∼5 for males and -2.5∼5 for females. The NCHS reference WAZ scores were -1∼4 and -1.5∼4.5 for males and females, respectively. When the WHZ was compared with the Korean standard, 2.2% of infants were malnourished and 19.5% were overnourished. There were no malnourished subjects according to the NCHS reference and 19.1% of the infants were overnourished. When the three Z-scores are considered together, 92.0% of the infants should a normal growth status, there was no malnutrition, and 8.0% of the infants were overnourished. The growth performance was evaluated differently according to the type of standards. Thus, it is necessary to set proper growth standards for infants, according to which classification of feeding methods is chosen. A longterm and careful assessment of infants's growth performances to develop any group of standards.

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실내공간의 잔향시간과 음향변수 측정방법 (Measurement of the Reverberation Time of Rooms with Reference to Other Acoustical Parameters)

  • 오양기;주진수;정광용;김선우
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2001년도 추계학술대회논문집 I
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    • pp.392-396
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    • 2001
  • Revision of KS, Korean Standards, is currently actively discussed. It is just the time for a new world class standards under the new system with WTO, World Trade Organization. This paper is a part of “Researchs on the Standards in the Building Acoustic Field”, as one of KS revision projects. The aim of this study is to define the requirements for measuring the reverberation time and other major room acoustical parameters.

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Accurate Measurement of Arsenic in Laver by Gravimetric Standard Addition Method Combined with High Resolution Inductively Coupled Plasma Mass Spectrometry

  • Lee, Kyoung-Seok;Kim, Hyeon-Ji;Yim, Yong-Hyeon;Kim, Jeongkwon;Hwang, Euijin
    • Mass Spectrometry Letters
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    • 제5권2호
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    • pp.57-61
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    • 2014
  • A gravimetric standard addition method combined with internal standard calibration has been successfully developed for the accurate analysis of total arsenic in a laver candidate reference material. A model equation for the gravimetric standard addition approach using an internal standard was derived to determine arsenic content in samples. Handlings of samples, As standard and internal standard were carried out gravimetrically to avoid larger uncertainty and variability involved in the volumetric preparation. Germanium was selected as the internal standard because of its close mass to the arsenic to minimize mass-dependent bias in mass spectrometer. The ion signal ratios of $^{75}As^+$ to $^{72}Ge^+$ (or $^{73}Ge^+$) were measured in high resolution mode ($R{\geq}10,000$) to separate potential isobaric interferences by high resolution ICP/MS. For method validation, the developed method was applied to the analysis of arsenic content in the NMIJ 7402-a codfish certified reference material (CRM) and the result was $37.07mg{\cdot}kg^{-1}{\pm}0.45mg{\cdot}kg^{-1}$ which is in good agreement with the certified value, $36.7mg{\cdot}kg^{-1}{\pm}1.8mg{\cdot}kg^{-1}$. Finally, the certified value of the total arsenic in the candidate laver CRM was determined to be $47.15mg{\cdot}kg^{-1}{\pm}1.32mg{\cdot}kg^{-1}$ (k = 2.8 for 95% confidence level) which is an excellent result for arsenic measurement with only 2.8 % of relative expanded uncertainty.