• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2008년 영문 학술대회
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• pp.622-627
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• 2008

Experiment of active noise control on supersonic jet noise was conducted by use of microjet injection. The microjets were injected to the shear layer of the main jet through 22 small holes at the lip of a rectangular nozzle. Based on the measurement of farfield sound pressure, it was found that the jet noise was effectively reduced by several dB(in some cases up to 10 dB). The power levels of all measurement points were also reduced by use of microjet injection. The microjet affected not only the broadband noise but also the screech tone noise. The sound pressure level, the frequency of the screech tone, and the structure of the jet could be changed by the microjet. Flow visualization with schlieren technique was also made to observe the effect of microjet on the flow field.

• 한국압력기기공학회 논문집
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• 제15권1호
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• pp.33-39
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• 2019

An 1,500MW advanced power reactor required the standard design approval by a Korean regulatory body in 2014. The reactor has been designed to have a 4-train independent safety concept and a passive auxiliary feedwater system (PAFS). The full power risk or core damage frequency (CDF) of 1,500MW advanced power reactor has been reduced more than that of APR1400. However, the risk during the low power and shutdown (LPSD) operation should be reduced because CDF of LPSD is about 4.7 times higher than that of internal full power. The purpose of paper is to analysis design alternatives to reduce risk during the LPSD. This paper suggests design alternatives to reduce risk and presents sensitivity analysis results.

• 한국압력기기공학회 논문집
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• 제14권2호
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• pp.41-48
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• 2018

In this study, the dynamic absorber and the damper are applied to improve the seismic performance of the piping system, and their quantitative effects on the piping system performance are examined. For this purpose, the response performances of piping system applied with the dynamic absorber/damper are compared with those of the original piping system. Firstly, the frequency response analyses of the piping system with the presence or the absence of dynamic absorber/damper are performed and these results are compared. It has been shown that the maximum acceleration response per the frequency of the piping system is considerably reduced by installing the dynamic absorber and the damper. Secondly, the seismic responses of the piping systems with and without dynamic absorber/damper are compared. As a result of the numerical analyses, it is confirmed that key responses are reduced by 17%-63% due to the installation of the dynamic absorber and damper. Finally, as a result of the seismic performance evaluation, it is confirmed that the HCLPF (High Confidence of Low Probability of Failure) seismic performances are increased by 1.22 to 2.70 times with respect to the failure modes with an aid of the dynamic absorber and damper.

• 한국분무공학회지
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• 제26권1호
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• pp.18-25
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• 2021

The objective of this study is to investigate the effect of cryogenic intake air temperature on the injected fuel droplet behavior in a compression ignition engine under the different start of energizing timing. To achieve this, the intake air temperatures were changed from -18℃ to 18℃ in steps of 9℃, and the result of fuel evaporation rate, Sauter mean diameter, and equivalence ratio distributions were compared. When the intake air temperature decreased in steps of 9℃, less fuel was evaporated by about 3.33% because the cylinder temperature was decreased. In addition, the evaporated fuel amount was increased with retarding the start of energizing timing because the cylinder temperature raised. However, the difference was decreased according to the retarded start of energizing timing because the cylinder pressure was also increased at the start of fuel injection. The equivalence ratio was reduced by 5.94% with decreasing the intake air temperature. In addition, the ignition delay was expected to longer because of the deteriorated evaporation performance and the reduced cylinder pressure by the low intake air temperature.

• The Korean Journal of Physiology and Pharmacology
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• 제26권6호
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• pp.511-518
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• 2022

Sepsis-associated myocardial injury, an invertible myocardial depression, is a common complication of sepsis. Neogambogic acid is an active compound in garcinia and exerts anthelmintic, anti-inflammatory, and detoxification properties. The role of neogambogic acid in sepsis-associated myocardial injury was assessed. Firstly, mice were pretreated with neogambogic acid and then subjected to lipopolysaccharide treatment to induce sepsis. Results showed that lipopolysaccharide treatment induced up-regulation of biomarkers involved in cardiac injury, including lactate dehydrogenase (LDH), creatine kinase-MB (CK-MB), and troponin I (cTnI). However, pretreatment with neogambogic acid reduced levels of LDH, CK-MB, and cTnI, and ameliorated histopathological changes in the heart tissues of septic mice. Secondly, neogambogic acid also improved cardiac function in septic mice through reduction in left ventricular end-diastolic pressure, and enhancement of ejection fraction, fractional shortening, and left ventricular systolic mean pressure. Moreover, neogambogic acid suppressed cardiac apoptosis and inflammation in septic mice and reduced cardiac fibrosis. Lastly, protein expression of p-p38, p-JNK, and p-NF-κB in septic mice was decreased by neogambogic acid. In conclusion, neogambogic acid exerted anti-apoptotic, anti-fibrotic, and anti-inflammatory effects in septic mice through the inactivation of MAPK/NF-κB pathway.

• 한국자동차공학회논문집
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• 제14권4호
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• pp.84-91
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• 2006

In this study, the effect of EGR and fuel injection pressure on the characteristics of combustion and emission performance of the common-rail diesel engine is investigated using DME fuel as a smoke-free alternative fuel. Because the heating value and density of DME fuel are lower than those of diesel fuel, the injection duration of the DME engine is relatively longer than the injection duration of the diesel engine with the same injection pressure. However, the higher injection pressure can shorten the injection duration for the DME engine. Although the smoke level of the DME engine is much lower than that of the diesel engine, the NOx is at a level similar to that of the diesel engine. As a proposed solution for this, the EGR technique is empirically applied to the DME engine. In the experiments, the injection pressure was changed from 200bar to 400bar, and the EGR rate was limited under 40%. With the same injection timing and fuel amount, the experiment results indicated that the increase of injection pressure led to the increase of IMEP while decreasing HC and CO emissions. However, the NOx emission tends to increase as the injection pressure becomes higher. On the other hand, as the EGR rate was increased, NOx emission and A/F were reduced while the HC and CO emissions were increased. Because HC and CO emissions have the critical A/F point where the emissions of HC and CO are rapidly increased, it is proposed that the EGR rate must be limited under the critical EGR rate.

• 전기의세계
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• 제22권5호
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• pp.19-32
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• 1973

This paper treats with some of plasma jet behaviors under magnetic field for the purpose of controlling important characteristics of plasma jet in the practices of material manufacturings. Under the existence and non-existence of magnetic field, the pressure distribution, flame length, stability and noise of plasma jet are comparatively evaluated in respect of such parameters as are current, gap of electrode, quantity of argon flow, magnetic flux density, diameter and length of nozzle. The results are as follows: 1) the pressure, the length and the noise of plasma jet rise gradually with the increase of are current, and have high values under identical arc current as the diameter of nozzle increases, but reverse phenomenon tends to appear in the noise. 2) The pressure, the flame length and the noise increase with the increased quantity of argon flow, and the rising slope of noise is particularly steep. Under magnetic field, the quantity of argon flow in respect of flame length has the critical value of 80(cfh). 3) The pressure and length of flame decrease with small gradient value as the length of gap increases, but the noise tends to grow according to the increase of nozzle diameter. 4) The pressure and the length of jet flame decrease inversly with the increase of magnetic flux density, which have one critical value in the 100 amps of arc current and two values in 50 amps. The pressure of jet flame can be below atomospher pressure in strong magnetic field. 5) "The constriction length of nozzle has respectively the critical value of 6(mm) for pressure and 23(mm) for the length of flame. 6) Fluctuations in the wave form of voltage become greater with the increase of argon flow and magnetic flux density, but tends to decrease as arc current increases, having the frequency range of 3-8KHz. The wave form of noise changes almost in parallel with that of voltage and its changing value increases with argon flow, arc current and magnetic flux density, having the freuqency range of 6-8KHz. The fluctuation of jet presurre is reduced with the increase of argon flow and magnetic flux density and grows with arc current.rent.

• Genomics & Informatics
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• 제10권1호
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• pp.40-43
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• 2012

Recent genomewide association studies of large samples have identified genes that are associated with blood pressure. The Global Blood Pressure Genetics (Global BPgen) and Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) consortiums identified 14 loci that govern blood pressure on a genomewide significance level, one of which is $CASZ1$ confirmed in both Europeans and Asians. $CASZ1$ is a zinc finger transcription factor that controls apoptosis and cell fate and suppresses neuroblastoma tumor growth by reprogramming gene expression, like a tumor suppressor. To validate the function of $CASZ1$ in blood pressure, we decreased $Casz1$ mRNA levels in mice by siRNA. $Casz1$ siRNA reduced mRNA levels by 59% in a mouse cell line. A polyethylenimine-mixed siRNA complex was injected into mouse tail veins, reducing $Casz1$ mRNA expression to 45% in the kidney. However, blood pressure in the treated mice was unaffected, despite a 55% reduction in $Casz1$ mRNA levels in the kidney on multiple siRNA injections daily. Even though $Casz1$ siRNA-treated mice did not experience any significant change in blood pressure, our study demonstrates the value of $in$ $vivo$ siRNA injection in analyzing the function of candidate genes identified by genomewide association studies.

• 한국화재소방학회논문지
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• 제27권1호
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• pp.52-59
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• 2013

본 연구에서는 초고층 건물 화재 등 고압방수가 필요한 상황에서 방수압력을 유지하기 위하여 소방펌프차의 중계방수방법과 활용방안을 정립하고자 시험을 실시하였다. 중계 방수압력의 변화에 대하여 시험결과 소방펌프차의 방수구를 개방하고 측정하였을 경우 방수구를 폐쇄한 상태에서 측정한 결과보다 약 20 %가 감소한 것으로 나타났다. 소방활동 현장에서 보다 더 효율적으로 활용하기 위하여 소방펌프차 2대의 압력을 각각 변화시키면서 시험한 결과에서도 비슷한 효율이 나타나는 것으로 확인되었다. 현재 고압 방수능력이 있는 소방펌프차가 소방서에 배치되어 있지 않고 소방펌프의 형식승인 및 검정기술기준에서도 고압 소방펌프에 대한 규정이 없기 때문에 현재 보유하고 있는 소방차를 활용하여 초고층 화재 등 고압방수의 필요성이 있는 화재현장에 효과적으로 대응하고자 본 연구 결과를 토대로 소방차량 운영 및 활용방안을 제안한다.

• Journal of Ginseng Research
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• 제21권2호
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• pp.119-124
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• 1997

Chronic hypertension is associated with impaired endothelial function such as reduced synthesis/release of endothelium-derived relaxing factor(EDRF, nitric oxide) and increased synthesis/release of endothelium-derived contracting factor(EDCF) including prostaglandin endoperoxide($PGH_2$) , superoxide anion both in animals and in humans. We have previously shown that ginsenosides lower the blood pressure and enhance the release of nitric oxide(NO) from endothelial cells in the rat aorta of the normotensive rats. The aim of the present study is to examine whether in vivo treatment of spontaneously hypertensive rats(SHRs) with protopanaxatriol ginsenosides(PPT) reduces the blood pressure and improves endothelial function in the isolated thoracic aorta of SHR. In addition, the contractile response to $PGH_2$ and superoxide anion in the aorta treated with PPT was assessed. SHRs at the age of 16 weeks were savaged with PPT(30 mg/kg/ day) for 2 weeks and systolic blood pressure was measured by the tail-cuff method. Whereas blood pressure was significantly increased in SHRs by 5.4 mmHg during this period of treatment, treatment of SHRs with PPT blocked the elevation of blood pressure. Endothelium-dependent relaxation to acetylcholine was significantly increased in the PPT-treated animals. $PGH_2$- and oxygen-derived free radical-induced contractions were significantly suppressed in aortic rings without endothelium from PPT-treated SHR. These findings indicate that PPT reduces the blood pressure of SHR, which may be associated with either increase of NO release or by antagonizing superoxide anion and PGH2 in the aortic smooth muscle.