• 한국산학기술학회논문지
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• 제19권4호
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• pp.211-220
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• 2018

본 연구는 지역사회 정신보건시설(정신건강증진센터와 정신재활시설)을 이용하는 정신장애인의 임파워먼트와 회복간의 관계에서 치료자와의 치료적 관계가 매개효과를 갖는지를 확인하기 위한 것이다. 자료수집 기간은 2015년 4월 15일부터 20일까지였고, 조사 대상은 지역사회에 거주하는 정신장애인 168명이었다. 연구도구는 임파워먼트, 치료적 관계도구, 회복척도였다. 자료분석은 SPSS/WIN 19.0 프로그램을 이용하여 기술통계, Person's correlation, 다중회귀분석방법으로 분석하였다. 대상자들의 임파워먼트와 회복은 $60.4{\pm}10.85$점, $101.8{\pm}20.70$이었고, 치료적 관계는 $74.5{\pm}14.30$점이었다. 임파워먼트와 치료적 관계 (r=.33, p<.001), 임파워먼트와 회복(r=.51, p<.001)간에는 유의한 양의 상관관계를 보였고, 치료적 관계와 회복간 (r=.55, p<.001)에는 유의한 양의 상관관계를 보였다. 임파워먼트와 회복간의 치료적 관계의 매개효과를 검정한 결과, 임파워먼트와 치료적 관계가 모두 회복에 유의한 영향을 주는 것으로 나타나 치료적 관계는 두 변수 간 관계를 부분 매개하는 것으로 나타났고, Sobel test을 통해 확인한 결과 매개효과는 통계적으로 유의하였다.(z=3.706, p<.001). 본 연구결과는 정신장애인의 치료자와의 관계 속에서 치료적 관계 증진을 도모하고 임파워먼트를 향상시킬 수 있는 실제적인 회복 증진 프로그램 개발을 위한 기초자료로 활용 될 수 있을 것이다.

• 국제물리치료학회지
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• 제2권1호
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• pp.193-200
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• 2011

This study is intended to examine the tDCS and Montoya stair task(MST) on sensorimotor recovery and glial scar expression in MCAo induced stroke model of rat. To achieve this goal, this study selected 80 SD rats of 8 weeks. The experiment groups were divided them into four groups, and assigned 20 rats to each group. Group I was a experimental control group; GroupII was a tDCS application group after MCAo; Group III was a MST application group after MCAo; Group IV was a tDCS and MST application group after MCAo. In each group, neurological function test measurement, motor behavior test, montoya stair task test, immunohistochemistric finding of GFAP expression finding were analyzed. In motor behavior test, the outcome of group I was significantly difference than the other group, especially from 14days. In montoya stair task test, the outcome of group I was significantly lower than the other group especially, group II were significantly different on 14days and group IV was most significantly difference than the other group. In immunohistochemistric finding, group II, III, IV were decrease GFAP expression on depend on time stream. These results throughout the MCAo due to focal ischemic brain injury rat model four weeks tDCS and MST was applied, when the neurobehavioural, upper extremity function and ability, histopathologic data suggest that sensorimotor function recovery and a positive influence on glial scar decrease and confirmed that.

• 동의생리병리학회지
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• 제19권3호
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• pp.760-764
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• 2005

This research was performed to investigate protective effect of Sophora Subprostrata fractions against focal ischemic brain damage after middle cerebral artery(MCA) occlusion. Rats were divided into six groups: MCA-occluded group(Control); each administered groups with Sophora Subprostrata total phase(Total), Sophora Subprostrata Aqueous phase (Aqueous), Sophora Subprostrata BuOH phase(BuOH), and Sophora Subprostrata Alkaloid phase(Alkaloid) after MCA-occlusion; sham-operated group(Sham). The right MCA was occluded by A poly-L-lysine coated 4-0 nylon suture thread through the internal carotid artery permanently. Sophora Subprostrata and fractions were administered orally(5mg/ml) for 7 days after MCA-occlusion. The behavior of ischemic rats were examined at 24 hours, 3, 5 and 7 days after MCA-occlusion from the views of 4 different aspects: posture & balance tests(4 subtests), reflex tests(6 subtests), muscle-tone tests(3 subtests), and foot-fault test. The results showed that 1) in muscle tone test, Sophora Subprostrata total phase only increased reduced muscle tone function from 3 to 7 days, 2) in reflex test, Sophora Subprostrata total and Aqueous phase increased fast recovery from 24 hours and 3 days, 3) in posture & balance test, Sophora Subprostrata total and Aqueous phase increased fast recovery from 24 hours, and Sophora Subprostrata BuOH and Alkaloid phase increased posture & balance function from 3 days, but 4) in motor function test, Sophora Subprostrata did not show effective recovery compared with control group. In conclusion, Sophora Subprostrata has protective effects against brain damage at the early stage of focal cerebral ischemia. Sophora Subprostrata total and Aqueous phase produced more pronounced protective effect against focal ischemic brain damage.

• 문화기술의 융합
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• 제10권1호
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• pp.411-417
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• 2024

재해 발생 시 주요 IT 인프라 중단을 최소화하고 연속적인 비즈니스 서비스를 제공하기 위한 재해복구 계획 및 재해복구시스템의 구축은 반드시 필요하다. 재해복구시스템 구축과정에서 데이터 복제는 재해 발생 시 중단 없는 연속적인 비즈니스 서비스 제공을 위한 데이터 복구의 핵심요소로 데이터 복제방식은 시스템 구성환경과 재해복구 목표수준에 따라 결정할 수 있다. 본 논문에서는 재해복구시스템 구축에서 구성환경과 재해복구 목표수준에 적합한 데이터 복제방식 결정 방안에 대해 제시한다. 또한 복제방식 결정 절차를 적용하여 재해복구시스템을 구축하고 구축 결과를 분석한다. 재해복구시스템 구축 후 재해 상황에서 재해복구센터로 서비스가 전환, 정상적인 서비스가 진행되는지를 판단하기 위한 모의 테스트를 진행하고 결과를 분석하였다. 그 결과 재해복구시스템 구축 단계에서는 체계적으로 최적의 데이터 복제방식의 선정이 가능했다. 구축된 재해복구시스템은 연속적인 비즈니스 서비스 제공을 위해 재해복구센터로 서비스 전환되는 시간 RTO는 3.7시간으로, Tier 2였던 재해복구 수준이 목표수준 RTO 4시간 이내, RPO=0으로 개선되었다.

• Journal of Korean Neurosurgical Society
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• 제40권4호
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• pp.267-272
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• 2006

Objective : There have been recent reports that mesenchymal stromal cells that are harvested from adipose tissue are able to differentiate into neurons. In the present study, we administered adipose tissue derived stem cells in rats with cerebral infarction in order to determine whether those stem cells could enhance the recovery of motor function. Methods : Cerebral infarction was induced by intraluminal occlusion of middle cerebral artery in rats. The adipose tissue-derived mesenchymal stem cells were harvested from inguinal fat pad and proliferated for 2 weeks in DMEM media. Approximately $1{\times}10^6$ cells were injected intravenously or into subdural space of the peri-lesional area. The rotor rod test was performed at preoperative state[before MCA occlusion], and 1, 2, 3, 4, 6, 8 and 10 weeks after the cell therapy. Results : The motor functions that were assessed by rotor rod test at 1 week of the cell therapy were nearly zero among the experimental groups. However, there was apparent motor function recovery after 2 weeks and 4 weeks of cell injection in intravenously treated rats and peri-lesionaly treated rats, respectively, while there was no significant improvement till 8 weeks in vehicle treated rats. Conclusion : These results demonstrate that the adipose derived stem cell treatment improves motor function recovery in rats with cerebral infarction.

• Journal of Korean Neurosurgical Society
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• 제49권2호
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• pp.83-91
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• 2011

Objective : Minocycline, a second-generation tetracycline-class antibiotic, has been well established to exert a neuroprotective effect in animal models and neurodegenerative disease through the inhibition of microglia. Here, we investigated the effects of minocycline on motor recovery and neuropathic pain in a rat model of spinal cord injury. Methods : To simulate spinal cord injury, the rats' spinal cords were hemisected at the 10th thoracic level (T10). Minocycline was injected intraperitoneally, and was administered 30 minutes prior surgery and every second postoperative day until sacrifice 28 days after surgery. Motor recovery was assessed via the Basso-Beattie-Bresnahan test Mechanical hyperalgesia was measured throughout the 28-day post -operative course via the von Frey test Microglial and astrocyte activation was assessed by immunohistochemical staining for ionized calcium binding adaptor molecule 1 (lba1) and glial fibrillary acidic protein (GFAP) at two sites: at the level of hemisection and at the 5th lumbar level (L5). Results : In rats, spinal cord hemisection reduced locomotor function and induced a mechanical hyperalgesia of the ipsilateral hind limb. The expression of lba1 and GFAP was also increased in the dorsal and ventral horns of the spinal cord at the site of hemisection and at the L5 level. Intraperitoneal injection of minocycline facilitated overall motor recovery and attenuated mechanical hyperalgesia. The expression of lba1 and GFAP in the spinal cord was also reduced in rats treated with minocycline. Conclusion : By inhibiting microglia and astrocyte activation, minocycline may facilitate motor recovery and attenuate mechanical hyperalgesia in individuals with spinal cord injuries.

• 한국직업건강간호학회지
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• 제26권3호
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• pp.172-183
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• 2017

Purpose: This study was conducted to investigate factors affecting the job embeddedness of workers in the manufacturing industry. Methods: The survey was conducted on 261 workers of the manufacturing industry in P city and Y city with the help of a structured self-report questionnaire, administered between June 10 and June 30, 2017. Data were analyzed using descriptive statistics, a t-test, ANOVA, a $Scheff{\acute{e}}s$ test, Pearson's correlation coefficients, and stepwise multiple regression. Results: There were significant differences in job embeddedness according to educational level, marital status, jobs and types of employment, satisfaction with salary, stress level, and the perceived health status of the subjects. There were significant positive correlations between role clarity of job demands (r=.45), leader member exchange (r=.48), recovery experience from job stress (r=.27), and job embeddedness. From the multiple regression analysis, the most significant factors affecting job embeddedness were found to be leader member exchange (${\beta}=.43$), recovery experience from job stress (${\beta}=.22$), and job demand (${\beta}=.15$). These variables explained 35.0% of the total variance in job embeddedness. Conclusion: In order to increase job embeddedness of workers in the manufacturing industry, it is necessary to prepare measures to increase job demand, leader member exchange, and recovery experience from job stress.

• 재활치료과학
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• 제4권2호
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• pp.84-91
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• 2015

본 연구는 해외 많은 분야의 재활에서 적용되고 있는 peer mentor 프로그램을 국내에 연구적, 임상적으로 도입하여 뇌졸중 환자의 정신적, 신체적 회복을 돕는 방법을 소개하고자 하였다. 두 집단 실험 설계로 뇌졸중이 발생한지 3-6개월인 환자들을 대상으로 설계하였다. 동료멘토는 뇌졸중이 발생한지 2년이 지난 외래 환자로 서로 다른 회복수준을 보이는 환자들로 구성하고, 프로그램을 운영하기에 앞서 참가자들에게 심리적, 평가적, 정보적인 도움을 주는 방법과 프로그램 운영 방법에 대해 교육한다. 한국판 노인 우울 척도 단축형 (Geriatric Depression Scale Short Form-Korea Version; GDSSF-K)을 사용하여 프로그램 참가자들의 심리적 요인을 측정하고, 뇌졸중 영향척도(Stroke Impact Scale; SIS)를 통해 회복수준을, 노인 상지 기능평가도구(Upper Extremity Function Test for the Elderly; TEMPA)을 사용하여 신체적 요인을 측정한다. 본 연구를 토대로 연구를 진행하고자 하는 연구자는 본 연구에서 제안한 방법과 더불어 뇌졸중 환자의 회복에 더 효과적인 프로그램 적용 방법에 대한 모색이 필요할 것이다.

• 설비공학논문집
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• 제26권1호
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• pp.1-7
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• 2014

A field test of a 70 kW heat pump system with flue gas heat recovery was performed by an experiment at the Korea Institute of Energy Research. The flue gas is exhausted from a 320 RT absorption chiller-heater in the heating season. Using this flue gas, source water of the heat pump is heated by a condensed-type heat exchanger in the chimney. The operating characteristics of the heat recovery heat pump system were analyzed. Based on the results of the experiments, operating maps were obtained, and an optimum operating range is suggested, in which the return and heat source water temperature are $51^{\circ}C$ and $31^{\circ}C$, respectively. Additionally, economic analysis of this system was conducted and about 50% energy cost savings can be expected in the heating season.

• 기본간호학회지
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• 제8권2호
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• pp.172-188
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• 2001

Purpose: The purpose of this research was to test the effectiveness of the nursing intervention, mutual goal setting, for patients who have had a mastectomy. Special reference was given to King's goal attainment theory and a theoretical framework for establishing an effective nursing strategy to enhance patient recovery is suggested. Method: This research employed a quasi-experimental design which consisted of pretest-posttest non-equivalent control and experimental groups. Data were collected from 37 patients who had a mastectomy and were hospitalized in the Department of Surgery of Y Medical Center from January 2001 to May 2001. The experimental group received the nursing intervention, mutual goal setting four times from the day before the operation to the fifth day after the operation while the control group received only routine nursing care. As postoperative recovery indicators, ROM of arm joints, arm circumference, pain, physical symptoms, oxygen saturation stress, anxiety and body image were measured. Result: The test results are as follows : 1) there were statistically significant differences between the experimental and control groups in extension and internal rotation of the shoulder Joint and flexion of the wrist joint. 2) there was no significant difference between the two groups in arm circumference. 3) there were no significant differences between the two groups in pain, physical symptoms, or oxygen saturation. 4) there were no significant differences between the two groups in stress, anxiety, or body Image. On the basis of research results, the following are recommended : 1) The effectiveness of nursing intervention in the acute recovery period as well as long term effects need to be investigated. 2) There is a need to develop an instrument to measure perception which facilitates goal attainment in the interactive setting between patients and nurses.