• The Journal of Asian Finance, Economics and Business
• /
• 제7권12호
• /
• pp.433-444
• /
• 2020

The purpose of this study is to analyze integrated reporting disclosure and its implications on investor reactions. The population in this study is all manufacturing companies listed on the Indonesia stock exchange from 2017 to 2019, totaling 171 companies, and the sampling technique used is purposive sampling method. The method used in this research is a quantitative description using the financial statements of manufacturing companies listed on the Indonesia stock exchange. The data analysis method used is multiple regression analysis with intervening variables using AMOS 24 software. The results of this study show a positive and significant effect of profitability (X1) and company size (X2) on integrated reporting (IR); a positive and insignificant effect of stakeholder pressure (X3) on integrated reporting (IR); a positive and significant effect of profitability (X1) and stakeholder pressure (X3) on investor reactions (Y); a positive and insignificant effect of firm size (X2) and integrated reporting (IR) on investor reactions (Y). Suggestions are that in further studies, we can increase the sample size by including other industries, and in addition to using annual reporting, we can also use other sources such as websites, press releases, and prospectuses to improve the robustness of this study by relying on other data sources.

• 한국전산구조공학회:학술대회논문집
• /
• 한국전산구조공학회 2000년도 봄 학술발표회논문집
• /
• pp.100-110
• /
• 2000

In practical design of girder bridges or reinforced concrete slab bridges with T-type piers, it is usually assumed that vertical movements of superstructures are completely restrained at the locations of bearings(shoes) on a cap beam of the pier, The resulting vertical reactions are applied to the bearing for the calculation of bending moments and shear forces in the cap beam. However, in reality, the overhang parts of the cap beam will deform under the dead load of superstructures and the live load so that it may act as an elastic foundation. Due to the settlement of the elastic foundation, the actual distribution of the reactions at the bearings along the cap beam may be different from that obtained under the assumption that the vertical movements are fixed at the bearings. In the present study, investigated is the effects of elastic deformations of the T-type pier on the distribution of reactions at the bearings along the cap beam through 3-dimensional finite element analysis. Herein, for this purpose the whole structural system including the superstructure and piers as well is analyzed. It appears that the conventional practice which neglects the elastic deformations of the cap beam exhibits considerably different distributions of the reactions as compared with those obtained from the present finite element analysis. It is, therefore, recommended that in order to assess the reactions at bearings correctly the whole structural system be analyzed using 3-dimensional finite element analysis.

• 대한한의학회지
• /
• 제16권1호통권29호
• /
• pp.227-249
• /
• 1995

Pursuant to the Medical Product Safety Administration Guidelines for safety assessment of Korean bee vonom for herb-acupuncture, rabbits were used for skin, eye balls, subcutaneous and muscle irritation test. The results were as follows; 1. The skin irritation test of bee venom for herb-acupuncture did not produce any irritation reactions, when the skin was covered with bee venom. 2. The eye irritation test produced moderate to severe stimulating reactions, once the eye mucous membrane was contacted with bee venom. 3. The subcutaneous and muscle irritation test of bee venom showed such local inflammatory reactions as death of cells, infiltration of inflamed cells, dropsical swelling, and congestion, once injected under the skin and in the muscle. As the results of the study on bee venom for herb-acupuncture indicate that severe reactions in such tests as eye balls, subcutancous and muscle irritation exist in the laboratory, more professional caution should be taken in clinical application of the therapy. In addition, further study on subacute, chronic toxicity and allergy reactions should be pursued.

• Bulletin of the Korean Chemical Society
• /
• 제35권7호
• /
• pp.2130-2134
• /
• 2014

A kinetic study is reported on nucleophilic substitution reactions of 4-nitrophenyl isonicotinate (7) with a series of cyclic secondary amines in MeCN. The plots of $k_{obsd}$ vs. [amine] curve upward for the reactions with weakly basic amines (e.g., morpholine, 1-(2-hydroxyethyl)piperazine, and piperazine) but are linear for those with strongly basic amines (e.g., piperidine and 3-methylpiperidine). The curved plots for the reactions with the weakly basic amines are typical for reactions reported previously to proceed through uncatalyzed and catalyzed routes with two intermediates (e.g., a zwitterionic tetrahedral intermediate $T^{\pm}$ and its deprotonated form $T^-$). In contrast, the linear plots for the reactions with the strongly basic amines indicate that the catalytic route (i.e., the deprotonation process to yield $T^-$ from $T^{\pm}$ by a second amine molecule) is absent. The Br${\o}$nsted-type plots for $Kk_2$ and $Kk_3$ (i.e., the rate constants for the uncatalyzed and catalyzed routes, respectively) exhibit excellent linear correlations with ${\beta}_{nuc}$ = 0.99 and 0.69, respectively. The effect of amine basicity on the reaction mechanism is discussed in detail.

• 한국전산구조공학회:학술대회논문집
• /
• 한국전산구조공학회 2003년도 봄 학술발표회 논문집
• /
• pp.487-495
• /
• 2003

Bearings at the obtuse corner are subjected to much larger vertical reactions than other bearings because of the geometric shape of skew bridges. The current relevant specifications require that additional bars should be disposed at the bottom of concrete deck slabs to deal with the large vertical reaction on bearings at the obtuse corner. In this study, new methods of reducing the magnitude of the vertical reaction on bearings at the obtuse corner by the stiffness adjustment of bearings were proposed. The basic concept of proposed methods was to redistribute support reactions by reducing the vertical stiffness of bearings at the obtuse corner showing a relatively large vertical reaction. For 45 simply supported skew bridges designed according to the current relevant specifications, the redistribution effect of vertical reactions by the stiffness adjustment of bearings was investigated. Parameters such as skew angle, girder spacing, and deck aspect ratio that affect the distribution of support reactions were considered. The results of the analyses show that the magnitude of the vertical reaction on bearings at the obtuse corner can be reduced to the levels of straight bridges by replacing the existing bearings at the obtuse corner with new ones having the value of 1/10 or 1/20 of the vertical stiffness of the existing bearings. The reduction effect of the vertical reaction on bearings at the obtuse corner increases as the girder spacing decreases and it is more pronounced when the deck aspect ratio is 2.0.

• Journal of Ginseng Research
• /
• 제20권1호
• /
• pp.1-6
• /
• 1996

Effects of Panax ginseng on allergic reactions were studied uslng various in vivo and in vitro experimental models such as 48-hr passive cutaneous anaphylaxis, mediators-induced skin reactions, histamine release from rat peritoneal mast cells, hexosaminidase release from RBL-2H3 cells, and lipoxygenase assay . In all of anti-allergic experiments we conducted, ginseng components (50% ethanol extract or ginseng total saponin or ginsenosides) extracted from Korean red ginseng, did not show significant anti-allergic actions. In 48-hr passive cutaneous anaphylaxis and mediators-induced skin reactions, 50% ethanol extract did not suppress hypersensitivity reactions. Total saponin, 50% ethanol extract, and 8 major ginsenosides did not show inhibitory effects on lipoxygeanse activity. Ginseng total saponin did not inhibit histamine release from rat peritoneal mast cells. All of the ginseng components mentioned above were also tested on RBL-2H3 cells, but none of them inhibited hexosaminidase release from this cell line. These results suggest that Panax ginseng does not have effects on allergic reactions at the level of 50% ethanol extract or total saponin used. All of 8 major saponin components tested ($Rb_1$, $Rb_2$, Rc, Rd, Re, Rf, $Rg_1$, $Rg_2$), did not inhibit lipoxygenase activity and degranulation events.

• 아동학회지
• /
• 제35권4호
• /
• pp.61-78
• /
• 2014

The study examined the pathways from maternal reactions to children's negative emotions to children's emotion intelligence through children's resilience by gender. The participants in this study comprised 413 elementary school 4th-6th graders (of which 214 were boys, and 199 were girls). They completed questionnaires on maternal reactions to children's negative emotions, children's resilience and levels of children's emotional intelligence. Data were analyzed by means of T-test and structural equation modeling. In the case of the male group, it was found that maternal emotion coaching, when done indirectly, but not directly, had an influence on their levels of emotional intelligence. On the other hand, in the case of the female group, it was found that emotion coaching, when done indirectly, as well as directly, had an influence on their levels of emotional intelligence. Therefore, these results indicate that children's resilience mediated the effects of maternal emotion coaching on emotional intelligence. It also found that there are distinct pathways from maternal reactions to children's negative emotions to emotion intelligence through resilience by gender.

• Journal of Electrochemical Science and Technology
• /
• 제7권2호
• /
• pp.179-184
• /
• 2016

The interface between the surface of a cathode material and the electrolyte gives rise to surface reactions such as solid electrolyte interface (SEI) and chemical side reactions. These reactions lead to increased surface resistance and charge transfer resistance. It is consequently necessary to improve the electrochemical characteristics by suppressing these reactions. In order to suppress unnecessary surface reactions, we coated cathode material using polypropylene (PP). The PP coating layer effectively reduced the SEI film that is generated after a 4.3 V initial charging process. By mitigating the formation of the SEI film, the PP-coated Li[(Ni_0.6Co_0.1Mn_0.3)_0.36(Ni_0.80Co_0.15Al0.05)_0.64)]O₂(NCS) electrode provided enhanced transport of Li⁺ ions due to reduced SEI resistance (R_SEI) and charge transfer resistance (R_ct). The initial charge and discharge efficiency of the PP-coated NCS electrode was 96.2 % at a current density of 17 mA/g in a voltage range of 3.0 ~ 4.3 V, whereas the efficiency of the NCS electrode was only 94.7 %. The presence of the protective PP layer on the cathode improved the thermal stability by reducing the generated heat, and this was confirmed via DSC analysis by an increased exothermic peak.

• Archives of Plastic Surgery
• /
• 제47권4호
• /
• pp.297-300
• /
• 2020

Hyaluronidase, an enzyme that breaks down hyaluronic acid, has long been used to increase the absorption of drugs into tissue and to reduce tissue damage in cases of extravasation of a drug. With the increasing popularity of hyaluronic acid filler, hyaluronidase has become an essential drug for the correction of complications and unsatisfactory results after filler injection. For this reason, when performing procedures using hyaluronic acid filler, a sufficient knowledge of hyaluronidase is required. In order for hyaluronidase to dissolve a hyaluronic acid filler, it must interact with its binding sites within the hyaluronic acid. The reaction of a filler to hyaluronidase depends on the hyaluronic acid concentration, the number of crosslinks, and the form of the filler. Hyaluronidase is rapidly degraded and deactivated in the body. Therefore, in order to dissolve a hyaluronic acid filler, a sufficient amount of hyaluronidase must be injected close to the filler. If the filler is placed subcutaneously, injection of hyaluronidase into the filler itself may help, but if the filler is placed within a blood vessel, it is sufficient to inject hyaluronidase in the vicinity of the vessel, instead of into the filler itself. Allergic reactions are a common side effect of hyaluronidase. Most allergic reactions to hyaluronidase are local, but systemic reactions may occur in infrequent cases. Since most allergic responses to hyaluronidase are immediate hypersensitivity reactions, skin tests are recommended before use. However, some patients experience delayed allergic reactions, which skin tests may not predict.

• Applied Microscopy
• /
• 제15권1호
• /
• pp.1-12
• /
• 1985

In this study, the pathway and date of migrating Primordial germ cells (PGCs) were observed light microscopically and ultrastructural changes of them during migration were observed by electron microscopic examination. For these purpose, alkaline phosphatase reactions were used for identifying the PGCs and acid phosphatase reactions were used for observing their degenerating activities. Also, effects of actinomycin D on the migration of PGCs were examined. According to these results, at the 9th gestation day, PGCs were observed in the endodermal cells of yolk sac, at the 11th gestation day, they were seen in the hindgut and then entered into the dorsal mesentery by the 13th gestation day. At the 14th gestation day, they were located in the genital ridges. When PGCs were located in the hindgut and genital ridges, the positive reactions of alkaline phosphatase were dominated, but acid phosphatase reactions were limited in all stage except they were in dorsal mesentery. However, these reactions were lessened in case of actinomycin D treatment. By electron microscopic examination, PGCs had pseudopodia, tail process, trailing cytoplasm and nuage as the ultrastructural characteristics. In addition, these morphological features were damaged by actinomycin D treatment.