• Journal of the Society of Naval Architects of Korea
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• v.40 no.2
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• pp.21-27
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• 2003

The phenomena of vortex shedding around a cylinder oscillating harmonically in a fluid at rest are investigated by a two-dimensional numerical simulation of the Navier-Stokes equations. The simulation is based on a vorticity-velocity integro-differential formulation dealing with vorticity, velocity and pressure variables. Three combinations of Reynolds number(Re) and Keulegan-Carpenter number(KC) were taken to investigate the associated vortex development around the cylinder in the different flow regimes. Drag and lift forces are computed to describe their dominant frequency modulation which is related to the vortex shedding and to the harmonic motion of the cylinder.

• Animal Systematics, Evolution and Diversity
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• v.13 no.2
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• pp.173-192
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• 1997

Three damselfishes, Dascyllus melanurus, Dascyllus trimaculatus and Poamcentrus nagasakiensis were collected in the coastal waters of Cheju Island, Korea, during the period from July 1994 to May 1997. These taxa were a new records to th Korean fish fauna. This study re-describe about family Pomacentridae (6 genera, 13 species) including 3 new recorded species and suggest the taxonomic key of family pomacentridae from Korea.

• Journal of Electrical Engineering and Technology
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• v.9 no.4
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• pp.1188-1195
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• 2014

This paper presents an analytical technique for reliability evaluation of electrical distribution network (EDN) containing distributed generation (DG). Based on hierarchical levels of circuit breaker controlling zones and feeder sections, a directed-relation-graph (DRG) for an END is formed to describe the hierarchical structure of the EDN. The reliability indices of EDN and load points can be evaluated directly using the formed DRG, and the reliability evaluation of an EDN containing DGs can also be done without re-forming the DRG. The proposed technique incorporates multi-state models of photovoltaic and diesel generations, as well as weather factors. The IEEE-RBTS Bus 6 EDN is used to validate the proposed technique; and a practical campus EDN containing DG was also analyzed using the proposed technique.

• IE interfaces
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• v.18 no.2
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• pp.193-204
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• 2005

The modeling of business processes is key component of any improvement or re-engineering endeavor. Present trends of business modeling methodologies are to include the social context of an organization. Although various methodologies have been developed specially for the business process field and have a social context, it is not in terms of goals and customers, but processes, activities, and tasks. We describe our stance on business process modeling, based on the viewpoint of goal and customer. First, we formalize a goal-oriented business process model and its evaluation mechanism. Second, we propose a methodology of business process modeling, which starts from perceiving and describing interactions between organization and customer from the customer's viewpoint.

• Industrial Engineering and Management Systems
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• v.12 no.2
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• pp.103-111
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• 2013

This paper discusses how to manage supply chain disruption risks from natural disasters or other low-likelihood-high-impact risk drivers. After the catastrophic earthquake in Eastern Japan and the severe flood in Thailand, most companies have been attempting to re-establish the business continuity plan to prevent their supply chain from disruption. However, the challenges for managers and individual risks are often interrelated, and thus, actions that mitigate one risk can end up being no contribution as a whole. In this paper, we describe a framework for assessing how much impact individual mitigation strategies have on the entire supply chain protection against disruption, using network reliability. We propose three categories of risk-mitigation approaches: Stabilization, Absorption, and Duplication. We analyze the situation under which each of these strategies is the best suitable. With a clear understanding of relations between these mitigation strategies and the entire supply chain risks, managers can select effective risk-reduction approaches to their supply chain.

• Journal of the Optical Society of Korea
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• v.7 no.1
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• pp.28-33
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• 2003

We describe the optimal design and the fabrication of a 2$\times$2 port optical device based on the thin film filter (TFF), and also propose a 4-channel OADM module using these devices. The optical performance of the proposed OADM module is evaluated theoretically and experimentally, and is compared to that of typical OADM modules using 1$\times$2 port optical devices for 4, 8, 16 and 32 drop channels in optical transmission systems. Since the 2$\times$2 port optical device accomplishes the function of wavelength multiplexing and demultiplexing simultaneously in the proposed OADM module, the insertion loss of through channels can be improved by 1.2 dB compare to that of typical OADM modules using 1$\times$2 port optical devices. In addition, both the size and the price of the module can be reduced to 40~50%.

• Mycobiology
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• v.49 no.2
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• pp.95-104
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• 2021

Species of the genus Aspergillus have a variety of effects on humans and have been considered industrial cell factories due to their prominent ability for manufacturing several products such as heterologous proteins, secondary metabolites, and organic acids. Scientists are trying to improve fungal strains and re-design metabolic processes through advanced genetic manipulation techniques and gene delivery systems to enhance their industrial efficiency and utility. In this review, we describe the current status of the genetic manipulation techniques and transformation methods for species of the genus Aspergillus. The host strains, selective markers, and experimental materials required for the genetic manipulation and fungal transformation are described in detail. Furthermore, the advantages and disadvantages of these techniques are described.

• Journal of Life Science
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• v.8 no.2
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• pp.226-226
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• 1998

Discovery of molecular chaperone has stimulate cell biologists and thus made it possible to re-examine the processes whereby proteins achieve and maintain their functional conformations within living cells. the term ‘Molecular chaperone’ was first coined to describe one particular protein involved in the assembly of nucleosomes, but the term has now been extended to describe the function of a wide variety of proteins that assist protein transport across membranes, folding of nascent polypeptide, the assembly and disassembly of oligomeric structures, and the recovery or removal of proteins damaged by various environmental stresses including heat shock. Progress of molecular chaperone research is still limited by the lack of 3-dimensional structural information and detailed interacts with taget proteins in the cell. However, several laboratories around the world are attempting to extend our knowledge on the functions of molecular chaperone, and such efforts seem justified to finally provide the answers to the most burning questions shortly.

• The Korean Journal of Rehabilitation Nursing
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• v.3 no.1
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• pp.80-97
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• 2000

The purpose of this study is to identify and describe a process of sexual adjustment of individuals with spinal cord injury: and to describe and explore positive and negative influences on the adjustment process. This qualitative study was conducted with 10 Korean individuals with spinal cord injury who had been physically disabled for more than one year. Data were collected and analysed at a same time using grounded theory method. Major categories of this study showed a process how the individuals with spinal cord injury adjust to their individual life as sexual beings. The process included and individual responses to the behavioral efforts including and . Initially physical aspects of sexuality seemed to be affected by spinal cord injuries. The changed physical aspects then influenced other aspects of their sexual life. Life satisfaction of each individual as a sexual being revealed as very subjective. It could be defined according to how the individual approved their sexual life no matter what and how much behavioral effort the person had done. In this study 3 types of sexual adjustment aspects were explored: 'Active adjustment' 'Passive adjustment' 'Maladjustment'. There were negative and positive factors influencing the adjustment process of individuals with spinal cord injury. Those factors might come from themselves, from families, or from social situations. Findings of this study suggested that sexual life of individuals with spinal cord injury should not be understood as a physical or behavioral matter. It was a combination of physical, psychological and social aspects of life. Therefore, appropriate rehabilitation programs for the sexual adjustment of individuals with spinal cord injury need to concern heterogeneous life values of them and obtain individualized services for each individual at a different stage of the sexual adjustment process.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3155-3160
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• 2016

Background: L-asparaginase (ASNase) is commonly used in the treatment of acute lymphoblastic leukemia (ALL) and natural killer (NK)/T-cell lymphoma. This study was designed to describe the incidence of toxicity associated with ASNase in Asian adults. Secondary objectives were to investigate the management and impact of toxicity on subsequent ASNase use, and to compare the actual management against current recommendations. Materials and Methods: In this retrospective, multi-center, observational study, Asian patients ${\geq}18$ years old who received ${\geq}1$ dose of the native E. coli ASNase from 2008 to 2013 were included. Patients were excluded if they did not receive ASNase. Endpoints of this study were development of specific toxicities, whether ASNase was discontinued or re-challenged, and developmentg of recurrent toxicity. All data analyses were performed using SPSS version 20.0. Results: A total of 56 patients were analyzed. Mean (${\pm}SD$) age was 36.2 (${\pm}15.2$) years old, with 62.5% being males, 55.4% with ALL and 28.6% with NK/T-cell lymphoma. Hypersensitivity (12.5%) was associated with the highest incidence of toxicity (6 out of 7 patients had Grade 3 and 4 toxicity), followed by 10.7% for hepatic transaminitis, 3.6% for non-CNS thrombosis and 1.8% each for hyperbilirubinemia and pancreatitis. Hypersensitivity recurred in the 3 patients who were re-challenged with E. coli ASNase. Conclusions: ASNase is associated with a wide range of toxicities, with hypersensitivity being the most commonly observed among Asian adult patients.