• 대한방사성의약품학회지
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• 제7권2호
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• pp.153-159
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• 2021

This article provides an efficient ¹⁸F-labeling protocol based on a rapid condensation reaction between 2-cyanobenzothiazole (CBT) and N-terminal cysteine-containing biomolecules. The ¹⁸F-labeled CBT (¹⁸F-1) was prepared by radiofluorination of the tosylated precursor 4 with 18-crown-6/K+/[¹⁸F]F- complex. Using the purified ¹⁸F-1, ¹⁸F-labeled peptide (¹⁸F-7) and protein (¹⁸F-8) could be synthesized efficiently under mild conditions. This strategy would provide a convenient approach for rapid and site-specific ¹⁸F-labeling of various peptides and proteins for in vivo imaging and biomedical applications.

• Investigative Magnetic Resonance Imaging
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• 제22권2호
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• pp.94-101
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• 2018

Purpose: To determine the value of the appearance of the high signal intensity halo sign for detecting carotid intraplaque hemorrhage (IPH) on maximum intensity projection (MIP) of time-of-flight (TOF) MR angiography (MRA), based on high signal intensity on magnetization-prepared rapid acquisition with gradient-echo (MPRAGE) sequencing. Materials and Methods: A total of 78 carotid arteries in 65 patients with magnetization-prepared rapid acquisition gradient-echo (MPRAGE) positive on carotid plaque MR imaging were included in this study. High-resolution MR imaging was performed on a 3.0-T scanner prior to carotid endarterectomy or carotid artery stenting. Fast spin-echo T1- and T2-weighted axial imaging, TOF, and MPRAGE sequences were obtained. Carotid plaques with high signal intensity on MPRAGE > 200% that of adjacent muscle on at least two consecutive slices were defined as showing IPH. Halo sign of high signal intensity around the carotid artery was found on MIP from TOF MRA. Continuous and categorical variables were compared among groups using the Mann-Whitney test and Fisher's exact tests. Results: Of these 78 carotid arteries, 53 appeared as a halo sign on the TOF MRA. The total IPH volume of patients with a positive halo sign was significantly higher than that of patients without a halo sign ($75.0{\pm}86.8$ vs. $16.3{\pm}18.2$, P = 0.001). The maximum IPH axial wall area in patients with a positive halo sign was significantly higher than that of patients without a halo sign ($11.3{\pm}9.9$ vs. $3.7{\pm}3.6$, P = 0.000). Conclusion: High signal intensity halo of IPH on MIP of TOF MRA is associated with total volume and maximal axial wall area of IPH.

• Bulletin of the Korean Chemical Society
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• 제35권3호
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• pp.938-940
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• 2014

This paper discusses a coherence-gated three-dimensional imaging system based on photorefractive holography, which was applied to imaging through turbid media with a view to developing biomedical instrumentation. A rapid response photorefractive device doped with 2,4,7-trinitro-9-fluorenylidene malononitrile was used to generate the hologram grating. The estimated depth resolution was $20{\mu}m$, which corresponds to the coherence length of the light source. In this coherence imaging system, tomographic imaging of a 3-dimensional object composed of a $50{\mu}m$ thick cylindrical layer was achieved. The proposed coherence imaging system using an organic photorefractive material can be used as an optical tomography system for biological applications.

• Investigative Magnetic Resonance Imaging
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• 제23권2호
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• pp.81-99
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• 2019

Recently, deep learning methods have shown great potential in various tasks that involve handling large amounts of digital data. In the field of MR imaging research, deep learning methods are also rapidly being applied in a wide range of areas to complement or replace traditional model-based methods. Deep learning methods have shown remarkable improvements in several MR image processing areas such as image reconstruction, image quality improvement, parameter mapping, image contrast conversion, and image segmentation. With the current rapid development of deep learning technologies, the importance of the role of deep learning in MR imaging research appears to be growing. In this article, we introduce the basic concepts of deep learning and review recent studies on various MR image processing applications.

• 비파괴검사학회지
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• 제29권4호
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• pp.283-292
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• 2009

Laser-based ultrasonic sensing requires the probe with fixed fecal length, but this requirement is not essential in laser-based ultrasonic generation. Based on this fact, we designed a pulsed laser-based ultrasonic wave propagation imaging (UWPI) system with a tilting mirror system for rapid scanning of target, and an in-line band-pass filtering capable of ultrasoaic mode selection. 1D-temporal averaging, 2D-spatial averaging, and 3D-data structure building algorithms were developed far clearer results allowing fur higher damage detectability. The imaging results on a flat stainless steel plate were presented in movie and snapshot formats which showed the propagation of ultrasound visible as a concentric wavefield emerging from the location of an ultrasonic sensor. A hole in the plate with a diameter of 1 mm was indicated by the scattering wavefields. The results showed that this robust UWPI system is independent of focal length and reference data requirements.

• 대한핵의학회지
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• 제13권1_2호
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• pp.55-60
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• 1979

The radiographic diagnosis of osteomyelitis can be suspected early with deep soft tissue swelling, but the actual bone changes of osteomyelitis may be delayed as long as 10 to 14 days after onset or may be totally aborted by antibiotic therapy. Recognition of osteomyelitis by bone imaging is far more rapid than by conventional radiographic examination and can be used on admission to establish the diagnosis. Ten patients suspected of having early, acute osteomyelitis were studied by TC-99m Pyrophosphate bone imaging. Radiographs taken at the same time were all negative. Of these 9 patients showed positive bone images. The bone imaging provides a safe, accurate, noninvasive technique for the early diagnosis of osteomyelitis.

• 반도체디스플레이기술학회지
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• 제6권1호
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• pp.49-52
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• 2007

The recent advances in digital imaging and computing technology have resulted in a rapid accumulation of digital media in the personal computing and entertainment industry. In addition, large collections of such data already exist in many scientific application domains such as the geographic information systems (GIS), digital library, trademark imaging, satellite imaging and medical imaging. Thus, the need for content-based retrieval from visual media, such as image and video data, is ever increasing rapidly in many applications.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제12권1호
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• pp.61-69
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• 2006

The Diagnostic Imagining Department essentially needs to be transformed by the plan of the room and the medical equipment which should be improved according to a rapid development in technology. And the room should be considered the scale and composition an the time of planning. Because this part is often influenced in a specific character of imaging equipment in the room. The researches on the scale and composition of Diagnostic Imaging Department were the main part in 1980's but after 1990's this kind of researches have not been enough. So this study has an intention of proposing basic data which is used in planning the Diagnostic Imaging Department by analyzing the actual condition of the area organization in general hospital.

• Korean Journal of Radiology
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• 제22권1호
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• pp.9-22
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• 2021

Diffusion-weighted (DW) magnetic resonance imaging (MRI) is a rapid, unenhanced imaging technique that measures the motion of water molecules within tissues and provides information regarding the cell density and tissue microstructure. DW MRI has demonstrated the potential to improve the specificity of breast MRI, facilitate the evaluation of tumor response to neoadjuvant chemotherapy and can be employed in unenhanced MRI screening. However, standardization of the acquisition and interpretation of DW MRI is challenging. Recently, the European Society of Breast Radiology issued a consensus statement, which described the acquisition parameters and interpretation of DW MRI. The current article describes the basic principles, standardized acquisition protocols and interpretation guidelines, and the clinical applications of DW MRI in breast imaging.

• 인포메이션 디스플레이
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• 제18권3호
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• pp.3-12
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• 2017

In the recent years, significant advances have been made in the development of small form-factor, low power, and low cost 3D-sensing devices based on depth-imaging technologies with real-time performance. This has led to the advent of devices and machines that are able to sense and understand the world, navigate in the environment, and interact naturally with their human users. Human-computer interactions based on touch sensing and speech recognition have already become mainstream, and the rapid developments in 3D sensing is paving the path towards the next level of machine intelligence and interactions. This paper discusses the recent developments in real-time 3D sensing technologies and their emerging system application.