• Tuberculosis and Respiratory Diseases
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• v.84 no.3
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• pp.226-236
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• 2021

Background: Although the Quidel Sofia rapid influenza fluorescent immunoassay (FIA) is widely used to identify influenza A and B, the diagnostic accuracy of this test remains unclear. Thus, the objective of this study was to determine the diagnostic performance of this test compared to reverse transcriptase-polymerase chain reaction. Methods: A systematic literature search was performed using MEDLINE, EMBASE, and the Cochrane Central Register. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and a hierarchical summary receiver-operating characteristic curve (HSROC) of this test for identifying influenza A and B were determined using meta-analysis. A sensitivity subgroup analysis was performed to identify potential sources of heterogeneity within selected studies. Results: We identified 17 studies involving 8,334 patients. Pooled sensitivity, specificity, and DOR of the Quidel Sofia rapid influenza FIA for identifying influenza A were 0.78 (95% confidence interval [CI], 0.71-0.83), 0.99 (95% CI, 0.98-0.99), and 251.26 (95% CI, 139.39-452.89), respectively. Pooled sensitivity, specificity, and DOR of this test for identifying influenza B were 0.72 (95% CI, 0.60-0.82), 0.98 (95% CI, 0.96-0.99), and 140.20 (95% CI, 55.92-351.54), respectively. The area under the HSROC for this test for identifying influenza A was similar to that for identifying influenza B. Age was considered a probable source of heterogeneity. Conclusion: Pooled sensitivities of the Quidel Sofia rapid influenza FIA for identifying influenza A and B did not quite meet the target level (≥80%). Thus, caution is needed when interpreting data of this study due to substantial betweenstudy heterogeneity.

• Nuclear Engineering and Technology
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• v.55 no.10
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• pp.3732-3753
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• 2023

The Real-time Analysis for Particle-transport and In-situ Detection (RAPID) Code System, developed based on the Multi-stage Response-function Transport (MRT) methodology, enables real-time simulation of nuclear systems such as reactor cores, spent nuclear fuel pools and casks, and sub-critical facilities. This paper presents the application of a novel fission matrix-based burnup methodology to the well-characterized JSI TRIGA Mark II research reactor. This methodology allows for calculation of nuclear fuel depletion by combination and interpolation of RAPID's burnup dependent fission matrix (FM) coefficients to take into account core changes due to burnup. The methodology is compared to experimentally validated Serpent-2 Monte Carlo depletion calculations. The results show that the burnup methodology for RAPID (bRAPID) implemented into RAPID is capable of accurately calculating the k_eff burnup changes of the reactor core as the average discrepancies throughout the whole burnup interval are 37 pcm. Furthermore, capability of accurately describing 3D fission source distribution changes with burnup is demonstrated by having less than 1% relative discrepancies compared to Serpent-2. Good agreement is observed for axially and pin-wise dependent fuel burnup and nuclear fuel nuclide composition as a function of burnup. It is demonstrated that bRAPID accurately describes burnup in areas with high gradients of neutron flux (e.g. vicinity of control rods). Observed discrepancies for some isotopes are explained by analyzing the neutron spectrum. This paper presents a powerful depletion calculation tool that is capable of characterization of spent nuclear fuel on the fly while the reactor is in operation.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1071-1071
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• 2001

Near-infrared spectroscopy (NIRS) is potentially a powerful and revolutionary technology for environmental analysis. It is supported by a large body of scientific and experiential knowledge. The instrumentation is well-developed, with easy-to-use, highly dependable instruments, but at the same time it is still developing, particularly with the production of more portable and rapid instruments, and more powerful software. NIRS is used globally in numerous industries for commodity analysis. Yet NIRS is largely unknown in the field of environmental chemistry and monitoring, and is not even routinely used in soil analysis, where the research literature on NIRS extends over four decades. Part of the explanation for the poor visibility of NIRS is the fact that NIRS is not routinely taught in Chemistry programs in universities, where most environmental chemists and environmental technicians are trained. This presentation examines the unique capabilities of NIRS, such as rapid, real-time analysis; analysis of whole samples; simultaneous analysis of multiple constituents; cost-effectiveness, and portability, as they match needs for analysis in several environmental areas. Examples of NIRS usage and published and unpublished results will be described for such areas as soil and sediment analysis; water quality monitoring; and nutrient loading in application of manures and sewage sludge (biosolids) to land. Present barriers to the use of NIRS in environmental analysis will be discussed. It is argued that emerging environmental problems and increasing attention to some traditional problems will enhance the application of NIRS in the future.

• Korean Journal of Soil Science and Fertilizer
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• v.33 no.4
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• pp.242-246
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• 2000

The Near Infrared Reflectance Spectroscopy(NIR) was used to evaluate nutritional diagnosis for rapid leaf analysis method, 177 'Fuji' apple and 130 'Campbell Early' grape leaves were measured by Near Infrared reflectance spectra in the NIR region(1,100~2.500nm). Total nitrogen content was measured by kjelldhal distillation, after salycilic acid-sulfuric acid digestion. An empirical equation to predict total nitrogen content from its spectral signature was developed by adapting the Near Infrared Reflectance Spectroscopy analysis(NIRa) technique and the results were apple-0.965(R). 0.086(SEC), grape-0.926(R), 0.152(SEC). Standard Error of Prediction(SEP) of NIRa for predicting the total nitrogen of apple and grape leaves was 0.360 and 0.210, respectively. It was concluded that Near infrared reflectance spectroscopy analysis is promising method for rapid analysis of apple and grape leaves.

• Journal of the Korean Society of Systems Engineering
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• v.9 no.2
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• pp.83-90
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• 2013

Integrated aircraft synthesis process for rapid analysis and design is described in this paper. Data flow between different analysis fields is described in details. All the data are divided into several groups according to importance and source of the data. Analysis of design requirements and certification regulations is carried out to determine baseline configuration of an aircraft. Overall design process can be divided into initial sizing, conceptual and preliminary design phases. Basic data for conceptual design are obtained from initial sizing, CAD and geometry analysis. Basic data are required input for weight, aerodynamics and propulsion analyses. Results of this analysis are used for stability and control, performance, mission, and load analysis. Feasibility of design is verified based on analysis results of each discipline. Design optimization that involves integrated process for aircraft analysis is performed to determine optimum configuration of an aircraft on a conceptual design stage. The process presented in this paper was verified to be used for light aircraft design.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.2
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• pp.121-126
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• 2015

In this research, a tool was developed for the rapid performance of three-dimensional finite element analysis (3D FEA) of a machine tool spindle system made of a shaft and bearings. It runs the FEA with data, such as the bearing stiffness and the coordinates of the points, to define the section of the shaft, bearing positions, and cutting point. developed for the spindle system and then implemented with the tool using an object-oriented programing technique that allows the use of the objects of the CAD system used in this research. Graphic user interfaces were designed for a user to interact with the tool. It provides rapid evaluation of the design of a spindle system, and therefore, it would be helpful to identify a near optimal design of a spindle system based on, say, static stiffness with design changes and, consequently, FEA.

• Earthquakes and Structures
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• v.15 no.5
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• pp.541-553
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• 2018

In this paper a limit analysis based procedure for the rapid evaluation of the in-plane seismic capacity of masonry arch bridges is carried out. Attention has been paid to the effect of the backfill on the collapse load. A parametric investigation has been performed by varying the rise/span ratio and the results have been compared with those obtained by finite element modelling. The comparison highlights the conservative feature of the proposed model in terms of ultimate loads and a good agreement in terms of collapse mechanisms.

• Proceedings of the KIEE Conference
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• 1994.11a
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• pp.27-29
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• 1994

Recently, the energy situation in Korea has been significantly changed. Rapid increase in electricity demand, tremendous financial need for new power plant construction, and environmental problem have led to search for more efficient energy production and energy conservation technologies. Due to the potential energy and cost savings to both electric utilities and industries, cogeneration will play an important role in the electric power and thermal energy supply in the future. In this study, we present the COGENMASTER computer model for optimal system configuration and economic analysis of cogeneration system. We also present several case studies with this module to analyze Korean cogeneration market. The result of this study will be useful to utility and industrial cogeneration planners for rapid analysis of cogeneration's value under a broad range of scenarios.

• Journal of the Korea Society of Computer and Information
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• v.23 no.11
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• pp.9-15
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• 2018

The Ministry of National Defense announced 'Defense Reform 2.0' that aims to strengthen the country's security for decrease of regional uncertainties, growing requirements for advanced technologies, and a need for more efficiency in the Republic of Korea(RoK) Armed Forces this year. It said RoK Armed Forces have to change efficiently in preparation for rapid decline in military service resources as demographic cliff turning into reality, and the rapid evolution of the "battlefield environment" caused by developments in military science and technologies. RoK Navy combat Management System(CMS) made by domestic proprietary technology since 2000s and development centered on Agency for Defense Development require design changes for added requirements. So in this paper, I propose method of design a low cost and high efficiency navy CMS architecture based on high performance server and virtualization technology. And I create a test environment for analysis performance and compare the performance of proposed navy CMS and existing navy CMS.

• Journal of Apiculture
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• v.32 no.1
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• pp.27-39
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• 2017

PCR-chip-based ultra-rapid multiplex PCRs for detection of six major infectious pathogens in honeybee were developed. The 6 kinds of major infectious pathogens in honeybee included Paenibacillus larvae causing American Foulbrood, Melissococcus plutonius causing European Foulbrood as bacteria, Ascosphaera apis (Chalkbrood), Aspergillus flavus (Stonebrood), Nosema apis and Nosema ceranae (Nosemosis) as fungi. The developed PCR-chip-based ultra-rapid multiplex PCR showed successful amplification for all six major pathogens in the presence of more than $10^3$ molecules. The time for confirming amplification (Threshold cycles; Ct-time) was about 7 minutes for two species, and about 9 minutes for four species. Total 40 cycles of PCR took 11 minutes 42 seconds and time for melting point analysis was 1 minute 15 seconds. Total time for whole PCR detection was estimated 12 minutes 57 seconds (40 cycles of PCR and melting point analysis). PCR-chip based ultra-rapid multiplex PCR using standard DNA substrates showed close to 100% accuracy and no false-amplification was found with honeybee genomic DNA. Ultra-rapid multiplex PCR is expected to be a fast and efficient pathogen detection method not only in the laboratory but also in the apiary field.