• Communications for Statistical Applications and Methods
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• v.30 no.3
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• pp.227-244
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• 2023

In this paper, a depth-based nonparametric test for a multivariate two-sample scale problem is proposed. The proposed test statistic is based on the depth-induced ranks and is thus distribution-free. In this article, the depth values of data points of one sample are calculated with respect to the other sample or distribution and vice versa. A comprehensive simulation study is used to examine the performance of the proposed test for symmetric as well as skewed distributions. Comparison of the proposed test with the existing depth-based nonparametric tests is accomplished through empirical powers over different depth functions. The simulation study admits that the proposed test outperforms existing nonparametric depth-based tests for symmetric and skewed distributions. Finally, an actual life data set is used to demonstrate the applicability of the proposed test.

• Journal of KIISE:Databases
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• v.36 no.4
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• pp.247-253
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• 2009

Rank learning and processing have gained much attention in the IR and data mining communities for the last decade. While other data mining techniques such as classification and regression have been actively researched to interoperate with RDBMS by using the tightly coupled or loose coupling approaches, ranking has been researched independently without integrating into RDBMS. This paper proposes a tightly coupled integration of the Ranking SVM into MySQL in order to perform the rank learning task efficiently within the RDBMS. We implemented new SQL commands for learning ranking functions and predicting ranking scores. We evaluated our tightly coupled integration of Ranking SVM by comparing it to a loose coupling implementation. The experiment results show that our approach has a performance improvement of $10{\sim}40%$ in the training phase and 60% in the prediction phase.

• BMB Reports
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• v.37 no.2
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• pp.199-205
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• 2004

The six lumbrokinase fractions (F1 to F6) with fibrinolytic activities were purified from earthworm Lumbricus rubellus lysates using the procedures of autolysis, ammonium sulfate fractionation, and column chromatography. The proteolytic activities on the casein substrate of the six iso-enzymes ranged from 11.3 to 167.5 unit/mg with the rank activity orders of F2 > F1 > F5 > F6 > F3 > F4. The fibrinolytic activities of the six fractions on the fibrin plates ranged from 20.8 to 207.2 unit/mg with rank orders of F6 > F2 > F5 > F3 > F1 > F4. The molecular weights of each iso-enzyme, as estimated by SDS-PAGE, were 24.6 (F1), 26.8 (F2), 28.2 (F3), 25.4 (F4), 33.1 (F5), and 33.0 kDa (F6), respectively. The plasminogen was activated into plasmin by the enzymes. The optimal temperature of the six iso-enzymes was $50^{\circ}C$, and the optimal pH ranged from pH 4-12. The four iso-enzymes (F1-F4) were completely inhibited by PMSF. The two enzymes (F5 and F6) were completely inhibited by aprotinin, TLCK, TPCK, SBTI, LBTI, and leupeptin. The N-terminal amino acid (aa) sequences of the first 20 to 22 residues of each fraction had high homology. All six isoenzymes had identical aa residues 2-3 and 13-15. The N-terminal 21-22 aa sequences of the F2, F3, and F4 isoenzymes were almost the same. The N-terminal aa sequences of F5 and F6 were identical.

• Journal of The Korean Association of Information Education
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• v.13 no.1
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• pp.69-76
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• 2009

This paper proposes a teaching plan of programming language class for university of education students amusingly with LEGO Mindstorms NXT robot. The goal of class is not fragmentary knowledge acquirement but problem-solving of maze. This robot communicates with GUI named NXT-G installed in computer via USB. GUI is not text-based but icon-based programming tool. This paper designs a semester with 3 steps such as beginner, intermediate, high-rank. Beginner step is consists of learning of basic functions such as GUI usage and several sensors of robot. Intermediate step is consists of solving of maze problem with low complexity. High-rank step is consists of solving maze problem with medium and high complexity. All maze problem-solving have 3 process with algorithm, flowchart, and programming with stack.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.10
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• pp.313-323
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• 2018

This study was conducted to develop an individualized upper extremity exercise program for patients after mastectomy and evaluate its effectiveness. A nonequivalent control-group pretest-posttest design was used for this investigation. Research participants were patients with breast cancer who underwent mastectomy at two university hospitals (experimental group, n=17; control group, n=16). The experimental group received an individualized upper extremity exercise program three times a week for 7 weeks. Data were analyzed by the ${\chi}^2-test$, Fisher's exact test, Mann-Whitney U-test and Wilcoxon Signed Rank test using SPSS WIN 21.0. Inter-group comparison revealed significant differences between pre-test and post-test in hands behind the back, flexion, abduction, external rotation, internal rotation, and grip strength. Moreover, the experimental group showed significant improvements in hands behind the back, flexion, abduction, external rotation, internal rotation, and grip strength relative to the control. In conclusion, the individualized upper extremity exercise program was shown to be an effective intervention to improve physical functions in upper limbs and shoulders. Therefore, this program should be applied to patients after mastectomy in clinics since many patients have suffered from decreased physical functions in upper extremities.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1819-1823
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• 2013

Objective: Microarray data were analyzed to explore key genes and their functions in progression of colorectal cancer (CRC). Methods: Two microarray data sets were downloaded from Gene Expression Omnibus (GEO) database and differentially expressed genes (DEGs) were identified using corresponding packages of R. Functional enrichment analysis was performed with DAVID tools to uncover their biological functions. Results: 631 and 590 DEGs were obtained from the two data sets, respectively. A total of 32 common DEGs were then screened out with the rank product method. The significantly enriched GO terms included inflammatory response, response to wounding and response to drugs. Two interleukin-related domains were revealed in the domain analysis. KEGG pathway enrichment analysis showed that the PPAR signaling pathway and the renin-angiotensin system were enriched in the DEGs. Conclusions: Our study to systemically characterize gene expression changes in CRC with microarray technology revealed changes in a range of key genes, pathways and function modules. Their utility in diagnosis and treatment now require exploration.

• Archives of Pharmacal Research
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• v.16 no.1
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• pp.6-12
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• 1993

To evaluate KR-10876, a new fluoroquinolone antibacterial agent, its effects on the central nervous system(CNS) were investigated in mmice as part of phamacological study, and the results were compared with those for ciprofloxacin and ofloxacin, two prototypes of quinolone antiabctrial agents. All the parameters indicative of CNS function and acute toxicity were measured by close observation of the animals at regular time intervals after oral treatment of test compounds. KR-10876 did not have any effect on the parameters measured at lower does (100, 300 mg/kg, p.o.), it caused ptosis, suppressed spontaneous locomotor activity, hypothemia, and prolonged hexobarbital-induced sleeping time. KR-10876 also had a slight effect on motor coordination only at high dose. Simialr to ciprofloxacin, KR-10876 did not protect mice from pentylenetetrazol-strychnine-, and electroshock-inducedl convulsions at doses tested. These findings demonstrate that KR-10876 affects CNS functions only at high doses. The rank order for effects is ofloxacin$\le$KR-10876>ciprofloxacin.

• Structural Engineering and Mechanics
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• v.42 no.2
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• pp.229-245
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• 2012

Bridge vibration displacements have been directly measured by LVDTs (Linear Variable Differential Transformers) or laser equipment and have also been indirectly estimated by an algorithm of integrating measured acceleration. However, LVDT measurement cannot be applied for a bridge crossing over a river or channel and the laser technique cannot be applied when the weather condition is poor. Also, double integration of accelerations may cause serious numerical deviation if the initial condition or a regression process is not carefully controlled. This paper presents an algorithm of estimating bridge vibration displacements using vibration strains measured by FBG (Fiber Bragg Grating) sensors and theoretical mode shapes of a simply supported beam. Since theoretically defined mode shapes are applied, even high modes can be used regardless of the quality of the measured data. In the proposed algorithm, the number of theoretical modes is limited by the number of sensors used for a field test to prevent a mathematical rank deficiency from occurring in computing vibration displacements.89The proposed algorithm has been applied to various types of bridges and its efficacy has been verified. The closeness of the estimated vibration displacements to measured ones has been evaluated by computing the correlation coefficient and by comparing FRFs (Frequency Response Functions) and the maximum displacements.

• Physical Therapy Korea
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• v.18 no.2
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• pp.27-34
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• 2011

The aim of this study was to determine the effect of action-observation training on arm function in people with stroke. Fourteen chronic stroke patients participated in action-observation training. Initially, they were asked to watch video that illustrated arm actions used in daily activities; this was followed by repetitive practice of the observed actions for 3 times a week for 3 weeks. Each training session lasted 30 min. All subject participated 12 training session on 9 consecutive training days. For the evaluation of the clinical status of standard functional scales, Wolf motor function test was carried out at before and after the training and at 2 weeks after the training. Friedman test and Wilcoxon signed rank test was used to analyze the results of the clinical test. There was a significant improvement in the upper arm functions after the 3-week action-observation training, as compared to that before training. The improvement was sustained even at two weeks after the training. This result suggest that action observation training has a positive additional impact on recovery of stroke-induced motor dysfunctions through the action observation-action execution matching system, which includes in the mirror neuron system.

• The Korean Journal of Applied Statistics
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• v.24 no.6
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• pp.1161-1168
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• 2011

The approximation for the distribution functions of nonparametric test statistics is a significant step in statistical inference. A rank sum test for dispersions proposed by Ansari and Bradley (1960), which is widely used to distinguish the variation between two populations, has been considered as one of the most popular nonparametric statistics. In this paper, the statistical tables for the distribution of the nonparametric Ansari-Bradley statistic is produced by use of polynomially adjusted normal approximation as a semi parametric density approximation technique. Polynomial adjustment can significantly improve approximation precision from normal approximation. The normal-polynomial density approximation for Ansari-Bradley statistic under finite sample sizes is utilized to provide the statistical table for various combination of its sample sizes. In order to find the optimal degree of polynomial adjustment of the proposed technique, the sum of squared probability mass function(PMF) difference between the exact distribution and its approximant is measured. It was observed that the approximation utilizing only two more moments of Ansari-Bradley statistic (in addition to the first two moments for normal approximation provide) more accurate approximations for various combinations of parameters. For instance, four degree polynomially adjusted normal approximant is about 117 times more accurate than normal approximation with respect to the sum of the squared PMF difference.