• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2004년도 추계학술대회 논문집 Vol.17
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• pp.472-475
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• 2004

Microarray-based DNA chips provide an architecture for multi-analyte sensing. In this paper, we report a new approach for DNA chip microarray fabrication. Multifunctional DNA chip microarray was made by immobilizing many kinds of biomaterials on transducers (particles). DNA chip microarray was prepared by randomly distributing a mixture of the particles on a chip pattern containing thousands of m-scale sites. The particles occupied a different sites from site to site. The particles were arranged on the chip pattern by the random fluidic self-assembly (RFSA) method, using a hydrophobic interaction for assembly.

• Journal of Communications and Networks
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• 제17권6호
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• pp.568-581
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• 2015

Predicting locations of users with portable devices such as IP phones, smart-phones, iPads and iPods in public wireless local area networks (WLANs) plays a crucial role in location management and network resource allocation. Many techniques in machine learning and data mining, such as sequential pattern mining and clustering, have been widely used. However, these approaches have two deficiencies. First, because they are based on profiles of individual mobility behaviors, a sequential pattern technique may fail to predict new users or users with movement on novel paths. Second, using similar mobility behaviors in a cluster for predicting the movement of users may cause significant degradation in accuracy owing to indistinguishable regular movement and random movement. In this paper, we propose a novel fusion technique that utilizes mobility rules discovered from multiple similar users by combining clustering and sequential pattern mining. The proposed technique with two algorithms, named the clustering-based-sequential-pattern-mining (CSPM) and sequential-pattern-mining-based-clustering (SPMC), can deal with the lack of information in a personal profile and avoid some noise due to random movements by users. Experimental results show that our approach outperforms existing approaches in terms of efficiency and prediction accuracy.

• 한국정보과학회논문지:시스템및이론
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• 제36권6호
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• pp.521-531
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• 2009

플래시 메모리는 하드디스크와 다른 물리적 특성을 가진다. 대표적으로 읽기연산과 쓰기연산의 비용이 다르고, 덮어쓰기(overwrite)가 불가능하여 소거연산(erase)이 선행되어야 한다. 이러한 물리적 제약을 소프트웨어적으로 보완해주기 위해서, 플래시 메모리를 사용하는 시스템은 대부분 플래시 변환 계층(Flash Translation Layer)을 사용한다. 현재까지 효율적인 FTL 기법들이 제안되었으며, 이들은 임의쓰기(random writes) 패턴보다 순차쓰기(sequential writes) 패턴에 훨씬 더 효율적으로 동작한단. 본 논문에서는 플래시 메모리 상에서 B-트리 인덱스를 효율적으로 생성, 유지하기 위한 새로운 기법을 제안한다. B-트리에 키의 삽입, 삭제, 수정 등치 연산을 수행하면 FTL에 비효율적인 임의쓰기 패턴을 많이 발생시키며, 결국 B-트리 인덱스 유지 비용이 커지게 된다. 제안하는 기법에서는 B-트리에서 발생되는 임의쓰기 패턴을 먼저 플래시 메모리의 쓰기 버퍼에 추가쓰기(append writes) 패턴으로 변환하여 저장하고, 추후 이를 FTL에 효율적인 순차쓰기 패턴으로 FTL에 전달한다. 다양한 실험을 통해 제안하는 기법이 기존의 기법보다 플래시 메모리 I/O 비용 측면에서 우수하다는 것을 보인다.

• Archives of Plastic Surgery
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• 제40권3호
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• pp.181-186
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• 2013

Background Partial or complete necrosis of a skin flap is a common problem. Polydeoxyribonucleotide (PDRN) can be extracted from trout sperm and used as a tissue repair agent. The aim of this study was to investigate whether PDRN could improve the survival of random pattern skin flaps in rats. Methods Twenty-two male Sprague-Dawley rats were randomly divided into two groups: the PDRN treatment group (n=11) and the control group (n=11). Caudally pedicled random pattern skin flaps were elevated on their dorsal skin and resutured. The treatment group received daily intraperitoneal administration of PDRN (8 mg/kg/day), and the control group received fluid vehicle (NaCl 0.9%, 8 mg/kg/day) from day 0 to day 6. On day 7, the flap survival was evaluated and the harvested tissue surrounding the demarcation line of the necrotic area was stained with H&E, anti-rat vascular endothelial cell growth factor (VEGF) antibody, and PECAM-1/CD31 antibody. Results The average necrotic area of the flap in the PDRN group was significantly smaller when compared with that of the control group. Histologic and immunohistochemical evaluation showed that granulation thickness score and VEGF-positive staining cells were marked higher in the PDRN group than in the control group. PECAM-1/CD31-positive microvascular densities were significantly higher in the PDRN group when compared with the control group. Conclusions This study confirms that PDRN improves the survival of random pattern skin flaps in rats. These results may represent a new therapeutic approach to enhancing flap viability and achieving faster wound repair.

• 식물조직배양학회지
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• 제25권5호
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• pp.309-313
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• 1998

본 연구는 국내의 경우 제주도의 일부지역에서만 자생하는 흑오미자(Schisandra nigra)를 RAPD법을 이용하여 자웅동주 및 자웅이주 식물의 특이적 Marker를 탐색하고저 실시 하였다. 10-mer로 구성된 80종류의 random primer를 사용하여 흑오미자를 분석한 결과 기존의 재배되고 있는 오미자(Schisandra chinensis) 또는 남오미자(Kadsura japonica)와는 다른 band pattern을 보여 주었다. 흑오미자의 자웅동주. 암그루, 숫그루의 3품종을 상기와 동일하게 80개의 primer를 사용하여 RAPD를 분석한 결과, 5종류의 random primer(OPA-17, OPA-19, OPB-3, OPB-9, OPB-16)에 대해서는 각 품종에 대한 특이적인 band가 검출되었다. 숫그루, 암그루 식물과는 다르게 자웅동주 식물은 3개체(1호 2호, 3호)간에도 서로 다른 band pattern을 보이는 특징을 갖고있다. 숫그루 특이적인 band pattern은 OPB-3 primer을 이용할 경우 750bp에서 검출되었고, 암그루는 OPA-19 primer에서 950bp, 1690bp와 OPB-3 primer의 경우 700bp에서 자웅동주 및 숫그루에서 나타나지 않는 band가 검출되었다. 이러한 결과는 흑오미자의 숫그루 및 암그루에서 나타난 특이적인 band가 유묘시기에 암ㆍ수 개체를 조기에 구별하는 genetic marker로 사용할 수 있으리라 기대된다.

• 대한두개안면성형외과학회지
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• 제20권4호
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• pp.239-245
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• 2019

Background: Lidocaine spray is a local anesthetic that improves random-pattern skin flap survival. The fractional ablative carbon dioxide laser (FxCL) produces vertical microchannels that delivers topically applied drugs to the skin. In this study, we hypothesized that FxCL therapy would enhance the lidocaine effect to improve random-pattern skin flap survival in rats. Methods: McFarlane random-pattern skin flaps were elevated in 48 rats, which were divided into four groups according to treatment: FxCL+lidocaine, FxCL, lidocaine, and nontreatment (control). On postoperative day 7, necrotic flap areas, the number of capillary vessels, and neutrophil count were evaluated. Anti-rat vascular endothelial growth factor (VEGF) and CD31 antibody activity were also evaluated by immunohistochemical staining. Results: Flap survival rate was $53.41%{\pm}5.43%$, $58.16%{\pm}4.80%$, $57.08%{\pm}5.91%$, and $69.08%{\pm}3.20%$ in the control, lidocaine, FxCL, and FxCL+lidocaine groups, respectively. Mean neutrophil count in the intermediate zone excluding the necrotic tissue was $41.70{\pm}8.40$, $35.43{\pm}6.41$, $37.23{\pm}7.15$, and $27.20{\pm}4.24cells/field$ in the control, lidocaine, FxCL, and FxCL+lidocaine groups, respectively. Anti-rat VEGF and CD31 antibody activity were the highest in the FxCL+lidocaine group. Conclusion: FxCL with lidocaine had a positive effect on random-pattern skin flap survival in rats. Thus, FxCL with lidocaine spray should be considered as a new treatment option to improve flap viability.

• 한국정밀공학회지
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• 제33권5호
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• pp.385-392
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• 2016

Recently in the display industry, demands for high-luminance and resolution of display devices have been steadily increasing. Generally, micro linear patterns are applied to an optical film in order to improve its properties of light. However, these patterns are easily viewed to eyes and moire phenomenon can be occurred. Micro random patterns are proposed as a method to solve these problems, increasing light-luminance and light-diffusion. However, conventional pattern manufacturing technologies have long processing times and high costs making it difficult to apply to large area molds. In order to combat this issue, micro-random patterns are formed by using a roll to plate indentation method along with abrasive paper tools composed of AlSiO2, SiC, and diamond grains. Also, forming properties, such as size and fill-factor of random patterns, are analyzed depending on type, mesh of abrasive paper tools, and indentation forces.

• 반도체디스플레이기술학회지
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• 제22권1호
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• pp.49-53
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• 2023

In this paper, we propose an antirandom pattern-based test method considering power consumption to compensate for the problem that the fault coverage through random test decreases or the test time increases significantly when the DUT circuit structure is complex or large. In the proposed method, a group unit test pattern generation process and rearrangement process are added to improve the problems of long calculation time and high-power consumption, which are disadvantages of the previous antirandom test.

• Computers and Concrete
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• 제24권6호
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• pp.561-570
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• 2019

Understanding the realistic behavior of concrete up to failure under different loading conditions within the framework of damage mechanics and plasticity would lead to an enhanced design of concrete structures. In the present investigation, QR (Quick Response) code based random speckle pattern is used as a non-contact sensor, which is an innovative approach in the field of digital image correlation (DIC). A four-point bending test was performed on RC beams of size 1800 mm × 150 mm × 200 mm. Image processing was done using an open source Ncorr algorithm for the results obtained using random speckle pattern and QR code based random speckle pattern. Load-deflection curves of RC beams were plotted for the results obtained using both contact and non-contact (DIC) sensors, and further, Moment (M)-Curvature (κ) relationship of RC beams was developed. The loading curves obtained were used as input data for material model parameters in finite element analysis. In finite element method (FEM) based software, concrete damage plasticity (CDP) constitutive model is used to predict the realistic nonlinear quasi-static flexural behavior of RC beams for monotonic loading condition. The results obtained using QR code based DIC are observed to be on par with conventional results and FEM results.

• KIEE International Transactions on Electrophysics and Applications
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• 제11C권2호
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• pp.23-27
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• 2001

Microarray-based DNA chips provide an architecture for multi-analyte sensing. In this paper, we report a new approach for DNA chip microarray fabrication. Multifunctional DNA chip microarrays were made by immobilizing many kinds if DNAs on transducers (particles). DNA chip microarrays were prepared by randomly distributing a mixture of the particles on a chip pattern containing thousands of micro meter-scale sites. The particles occupied different sites from array to array. Each particle cam be distinguished by a tag that is established on the particle. The particles were arranged on the chip pattern by the random fluidic self-assembly (RFSA) method, using hydrophobic interaction.