• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권2호
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• pp.195-201
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• 1995

This is a case report of calcifying aponeurotic fibroma occurred in the right pterygopalatine fossa & ramus area accompanied by adenoid cystic carcinoma of the right sublingual gland of a 44-year-old female. Calcifying aponeurotic fibroma is benign tumor, but it is characterized by poorly marginated, infiltrated growth pattern and a stubborn tendency to local recurrence, but there is no record of malignant transformation or metastasis, and surgical management should be conservative(excision and reexcision). Most cases been reported at the hands and feet, but no reported case occuring in the head region is found in the literature. Adenoid cystic carcinoma is a slow-growing infiltrative tumor with high recurrence rate, and it's treatment requires radical excisin and radiotherapy. Wide surgical excision of tumor, RND and partial resection of mandible were done. And then, immediate mandibular reconstruction was performed by means of reimplantaion technique after autoclaving of the resected bone.

• 대한두개안면성형외과학회지
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• 제21권2호
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• pp.114-118
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• 2020

Adenoid cystic carcinoma (ACC) in the lacrimal gland is a very rare disease with poor overall prognosis. Its primary treatment is surgical excision, including orbital exenteration and radical orbitectomy, which is combined with radiotherapy and chemotherapy. Age, histopathologic type, bone invasion, and tumor extent are known factors that affect the prognosis of ACC. Furthermore, perineural invasion is highly associated with local tumor recurrence and tumor base invasion. Here, we report a rare case of ACC in the lacrimal gland with superior sagittal sinus invasion that repeatedly recurred after the surgical excision.

• 대한세포병리학회지
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• 제7권1호
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• pp.75-78
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• 1996

We experienced a case of infiltrating lobular carcinoma of the breast in the ascitic fluid. The patient was a 49 year-old woman who presented with a palable mass of 3 months duration in the left upper quadrant of the abdomen and abdominal distension. Five years ago, she had undergone left radical mastectomy with chemotherapy and radiotherapy for infiltrating lobular carcinoma of the breast. The ascitic fluid smears revealed singly scattered small round to elliptical cells, many of which were arranged in characteristic indian-file patterns consisting of 3 to 5 cells. The tumor cells had scanty cytoplasm, rare cytoplasmic vacuoles and marked chromatin clumping with small, but prominent nucleoli.

• 대한두개안면성형외과학회지
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• 제21권1호
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• pp.41-44
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• 2020

In general, patients with neurofibromatosis type I have a higher risk than those with other types of neurofibromatosis of developing soft-tissue sarcomas related to the nervous system. We here present a 42-year-old man with neurofibromatosis type I who developed a protruding mass over only 2 weeks. The histopathological diagnosis was epithelioid sarcoma. Epithelioid sarcomas are rare and, to the best of our knowledge, no epithelioid sarcomas have been reported in patients with neurofibromatosis type I. Radical excision of the primary lesion was performed and postoperative radiotherapy and chemotherapy administered, as is recommended for epithelioid sarcoma. Our case emphasizes that patients with neurofibromatosis type I may develop malignant tumors.

• 대한두경부종양학회지
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• 제8권1호
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• pp.44-49
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• 1992

Malignant schwannoma is a rare tumor arising from the schwann sheath of the nerve fibers. It spreads early to reginal node and metastasis to the lung. Radical surgery have performed for treatment of choice but combined modalities such as radiotherapy or adjuvant chemotherapy have been recommanded recently. The authors experienced two cases of malignant schwannoma originating from the ethmoid sinus and ventricular fold of larynx. and we report these cases briefly.

• 대한두경부종양학회지
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• 제15권2호
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• pp.239-242
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• 1999

Spindle cell carcinomas of the head and neck are unusual neoplasms that are histologically biphasic, having both squamous cell carcinoma and apparently malignant spindle cell or sarcomatous element. Controversy about the histogenesis of these tumors has resulted in various terminology ; sarcomatoid carcinoma, pseudosarcoma, carcinosarcoma, and spindle cell carcinoma. The clinical course and natural history of these tumors are also variable. We report a case of 64-year-old male who complained of a neck mass. The patient was treated with extended radical neck dissection and postoperative radiotherapy, but the primary site of spindle cell carcinoma could not be found. We reviewed the clinical course, treatment, prognosis, and histogenesis of spindle cell carcinoma of the head and neck.

• Journal of Chest Surgery
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• 제22권5호
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• pp.867-872
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• 1989

Primary mediastinal immature teratoma is a rare germinal tumor which includes various elements of mature teratoma, choriocarcinoma, yolk sac carcinoma, embryonal carcinoma, and seminoma in some proportions. The tumor is virtually restricted to young man and the response to surgery and radiotherapy are poor. Recently, we experienced a case of primary mediastinal immature teratoma with elevated serum [-HCG and [-fetoprotein in 18 years old man. The well-encapsulated mass, weighing 4.5 kg, was completely resected and then adjuvant combination chemotherapy was tried with Vincristine, Bleomycin, and Cisplatin. Radical excision of tumor and adjuvant chemotherapy would appear to produce better result than have been reported in other cases. The postoperative course was uneventful and the tumor markers were returned to normal range.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1976년도 제10차 학술대회연제 순서 및 초록
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• pp.86.3-86
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• 1976

외이도의 편평상피암은 드믄 질환으로 진단이 내려질 때는 이미 상당히 침범되어 외이도와 중이가 다 같이 침범되어 있는 경우가 대부분이다. 최근 저자들은 외이도에 발생한 편평상피암 1례를 경험하고 외이도의 광범위한 절제술 및 유양돌기 절개근치술과 술후 방사선 치료를 하였기에 문헌적 고찰과 더불어 보고하는 바이다.

• Medical Lasers
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• 제9권2호
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• pp.103-109
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• 2020

Transoral microsurgery has come a long way as a go-to surgical intervention technique for head and neck cancers. This minimally invasive procedure had gained acceptance through comparative clinical studies against radical neck surgical procedures, radiotherapy, and chemotherapy. Laser technology has vastly improved the oncological outcomes of this procedure and brought about an appreciation of transoral laser surgery (TLM) as a mainstay for re-sectioning malignant tumors along the throat. As an established procedure, TLM has undergone several upgrades regarding the different energy devices used for cutting, ablation, and hemostasis. Continued advances in automation have eventually led to surgical robotics, resulting in the emergence of transoral robotic surgery (TORS) as a viable advanced alternative for TLM. Similarly, expansions and enhancements (image-based guidance, fluorescence spectroscopy, and advanced robotic system) have also been investigated as potential upgrades for TORS. This paper reviews a selection of publications on the significant technological advancements to TLM and TORS over the past five years.

• Radiation Oncology Journal
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• 제21권1호
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• pp.27-34
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• 2003

목적 : 간외담관암 환자들의 수술 후 방사선치료 성적을 조사하여, 방사선치료의 역할과 생존율에 영향을 주는 인자들을 분석하고자 하였다. 대상 및 방법 : 1991년 10월부터 2001년 7월까지 간외담관암으로 근치적 절제술 후에 방사선치료를 받은 21명을 대상으로 하였다. 환자들의 연령은 39$\~$75세(중앙값 61세)였고, 남여의 비는 16:5였다. 근위부 담관암이 14명이었고, 원위부 암이 7명이었다. 수술 후 조직 검사에서 미세 병변이 19명에서 남았고, 림프절 전이가 7명에서 관찰되었다. AJCC 병기는 I, II, III 기가 각각 10, 10, 1명이었다. 총방사선량은 4,500$\~$6,300 cGy의 범위(중앙값 5,040 cGy)였고, 추적 조사 기간은 20$\~$81개월(중앙값 57.5개월)이었다 결과 : 3년, 5년 생존율이 각각 41.0$\%$, 29.3$\%$였고, 3년, 5년 무병 생존율은 각각 41.6$\%$, 29.7$\%$였다. 생존율에 영향을 주는 변수로 연령, 성별, 종온기 위치, 분화도, 수술 후 미세 병변의 잔존 유무, 신경 침범, 7 병기, N 병기, 병기, 방사선량, 화학요법 유무 등을 조사하여서, 단변량 분석에서 T 병기와 병기가 유의하였지만(p<0.05), 대상 환자의 수가 적어서 의미를 주기에는 제한이 있었다 12명(57.1$\%$)에서 재발이 발생되었는데, 국소 부위가 5명, 원격 전이가 4명, 국소 및 원격 전이가 동반된 경우가 3명이었고, 원격 전이 부위로는 간이 6명, 뼈가 1명이었다. 급성 부작용으로 2, 3도 백혈구 감소증이 각각 1명에서 발생되었고, 만성 부작용으로 2도 소화성 궤양이 4명에서 발생되었으나, 모두 보조적 치료로 회복되었다 결론 : 간외담관암 환자들에서 근치적 절제술 후의 방사선치료는 심각한 부작용의 발생 없이 적용 가능하며, 수술후 방사선치료의 효과와 예후 인자의 분석을 위해서는 보다 많은 환자들을 대상으로 전향적인 연구가 요구된다.