• Radiation Oncology Journal
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• 제36권1호
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• pp.1-10
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• 2018

Intensity-modulated radiation therapy (IMRT) has been considered the most successful development in radiation oncology since the introduction of computed tomography into treatment planning that enabled three-dimensional conformal radiotherapy in 1980s. More than three decades have passed since the concept of inverse planning was first introduced in 1982, and IMRT has become the most important and common modality in radiation therapy. This review will present developments in inverse IMRT treatment planning and IMRT delivery using multileaf collimators, along with the associated key concepts. Other relevant issues and future perspectives are also presented.

• 대한방사선치료학회지
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• 제2권1호
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• pp.81-85
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• 1987

It has been evident since 1972 that computed tomography(CT) can play an important role in treatment and managment of the cancer patients as four steps; diagnosis, satging Treatment and follow-up. In this paper, we intended to investigate the availability of CT scan and treatment planning computer in 700 cancer patients who have undergone radiation therapy at the division of radiation therapy, Kangnam St. Mary's Hospital, Catholic Medical College between Mar. 1983 and Dec. 1985. The result were as follow; 1. Of 700 irradiated cancer patients, 342 patients ($48.9\%$) were performed CT scan prior to radiation therapy. 2. The distribution of lesions in 342 patients having CT scans was like this; CNS (83 of 104 patients, $79.8\%$), abdomen (44 of 76 patients, $57.9\%$), pelvis (100 of 188 patients, $53.2\%$) etc. in order. 3. The treatment planning computer were used in 280 cancer patients ($40\%$). 4. Of the 280 cancer patients using treatment planning computer, 167 patients ($59.6\%$) applied diagnostic CT scan and remaining 113 patients ($40.4\%$) were made body contour to be used for radiation therapy planning by the treatment planning computer. Authors also made some magnification devices used for small multiformat CT images to magnify into life size, consisting of overhead projector (3M) I.V. stand and mirror. These enabled us to make less errors in tracing the small-sized CT images during input of the anatomical data into the treatment planning computer.

• 대한방사선치료학회지
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• 제22권1호
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• pp.41-46
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• 2010

목 적: 유방암의 접선조사 시 쐐기필터를 이용한 Conventional RT 기법과 정적다엽조리개를 이용한 FiF-IMRT 기법을 이용하여 전산화 치료계획 시 발생하는 선량분포의 차이를 환자의 유방 크기와 형태에 따라 분류하여 비교 분석하고자 한다. 대상 및 방법: 유방암 환자 30명을 대상으로 Eclipse treatment planning system ($Varian^{TM}$, USA, V8.0)을 사용하여 전산화 치료 계획을 시행하여 유방의 크기와 형태에 따라 분류하고, Dose Volume Histogram (DVH)을 이용하여 Conformity Index (CI)와 Homogeneity Index (HI)를 비교 분석하였다. 결 과: CI값은 ${\pm}1.2%$의 차이를 나타냈으며 FiF-IMRT의 경우 Conventional RT보다 HI값이 평균 1.67% 낮은 값으로 유방의 크기와 형태에 따른 분류값과 ${\Delta}HI$ (%)값의 상관관계를 알아본 결과 단면길이와 부피에서 높은 상관관계를 보였으며 통계적으로 유의(P<0.01)하였다. 결 론: 유방의 단면 길이와 부피가 증가할수록 Conventional RT의 경우보다 FiF-IMRT로 전산화 치료계획 시 유방 내의 선량 균등성이 향상되었으며 유방의 크기에 따라 그 효과가 다르므로 유방의 크기에 따른 적절한 치료계획이 필요할 것으로 생각된다.

• Journal of Yeungnam Medical Science
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• 제25권2호
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• pp.85-91
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• 2008

Intensity-modulated radiation therapy (IMRT) is believed to be one of the best radiation treatment techniques. IMRT is able to deliver fatal doses of radiation to the tumor region with minimal exposure of critical organs. It is essential to have a comprehensive quality assurance program to assure precision and accuracy in treatment, due to the character of IMRT. We applied quality assurance technique to the Eclipse treatment planning system and sought to determine its effectiveness in patient treatment planning. An acrylic phantom, film, and an ionization chamber were used in this study.

• 대한방사선치료학회지
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• 제5권1호
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• pp.92-94
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• 1992

• 한국의학물리학회지:의학물리
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• 제33권3호
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• pp.25-35
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• 2022

Purpose: Planning for radiotherapy relies on implicit estimation of the probability of tumor control and the probability of complications in adjacent normal tissues for a given dose distribution. Methods: The aim of this pilot study was to reconstruct dose-volume histograms (DVHs) from text files generated by the Eclipse treatment planning system developed by Varian Medical Systems and to verify the integrity and accuracy of the dose statistics. Results: We further compared dose statistics for intensity-modulated radiotherapy of the head and neck between the Eclipse software and software developed in-house. The dose statistics data obtained from the Python software were consistent, with deviations from the Eclipse treatment planning system found to be within acceptable limits. Conclusions: The in-house software was able to provide indices of hotness and coldness for treatment planning and store statistical data generated by the software in Oracle databases. We believe the findings of this pilot study may lead to more accurate evaluations in planning for radiotherapy.

• Radiation Oncology Journal
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• 제11권1호
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• pp.167-174
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• 1993

Recently, stereotactic radiosurgery plan is required with the information of 3-D image and dose distribution. A project has been doing if developing LINAC based stereotactic radiosurgery since April 1991. The purpose of this research is to develop 3-D radiosurgery planning system using personal computer. The procedure of this research is based on two steps. The first step is to develop 3-D localization system, which input the image information of the patient, coordinate transformation, the position and shape of target, and patient contour into computer system using CT image and stereotactic frame. The second step is to develop 3-D dose planning system, which compute dose distribution on image plane, display on high resolution monitor both isodose distribution and patient image simultaneously and develop menu-driven planning system. This prototype of radiosurgery planning system was applied recently for several clinical cases. It was shown that our planning system is fast, accurate and efficient while making it possible to handle various kinds of image modalities such as angiography, CT and MRI. It makes it possible to develop general 3-D planning system using beam's eye view or CT simulation in radiation therapy in future.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.2051-2054
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• 2015

Background: Radiation therapy is a key part of the combined modality treatment for Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL), which can achieve locoregional control of disease. The 3D-conformal radiation oncology can be extended-field (EFRT), involved-field (IFRT) and involved node (INRT). New techniques have resulted in a smaller radiation field and lower dose for critical organs such as lung heart and breast. Materials and Methods: In our research, we made a virtual simulation for one patient who was treated in four different radiotherapeutic techniques: mantle field (MFRT), EFRT, IFRT and INRT. After delineatiion we compared dose-volume histograms for each technique. The fusion of CT for planning radiotherapy with the initial PET/CT was made using Softver Xio 4.6 in the Focal program. The dose for all four techniques was 36Gy. Results: Our results support the use of PET/CT in radiation therapy planning. With IFRT and INRT, the burden on the organs at risk is less than with MFRT and EFRT. On the other hand, the dose distribution in the target volume is much better with the latter. Conclusions: The aim of modern radiotherapy of HL and NHL is to reduce the intensity of treatment and therefore PET/CT should be used to reduce and not increase the amount of tissue receiving radiation.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.61-64
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• 2002

As intensity modulated radiation therapy compared with conventional radiation therapy, tumor target dose increased and normal tissues and critical organs dose reduced. In brain tumor, treatment planning of intensity modulated radiation therapy was practiced in 4MV, 6MV, 15MV X-ray energy. In these X-ray energy, was considered the dose distribution and dose volume histogram. As 4MV X-ray compared with 6MV and 15MV, maximum dose of right optic-nerve increased 10.1 %, 8.4%. Right eye increased 5.2%, 2.7%. And left optic-nerve, left eye, optic chiasm and brainstem incrased 1.7% - 5.2%. Even though maximum dose of PTV and these critical organs show different from 1.7% - 10.1% according to X-ray energies, these are a piont dose. Therefore in brain tumor, treatment planning of intensity modulated radiation therapy in 9 treatment field showed no relation with energy dependency.

• 한국의학물리학회지:의학물리
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• 제22권4호
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• pp.178-183
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• 2011

본 연구에서는 토모테라피를 이용한 폐종양의 방사선수술 치료계획을 수립한 후 기존의 선형가속기를 사용하였을 경우와 비교, 분석하여 선량분포 측면에서 유효성 및 타당성을 살펴보았다. 종양의 움직임이 5 mm 이하인 10명의 환자 CT 영상을 대상으로 기존의 선형가속기를 이용한 세기조절방사선수술에서와 동일한 처방선량과 동일한 조건의 중요장기 선량제한치로 토모테라피 치료계획을 수립한 후 선량분포를 비교하였다. 토모테라피를 이용한 결과에서도 기존의 선형가속기를 이용한 세기조절방사선수술과 동일하게 중요장기의 선량제한치를 충족시키면서 GTV에 처방선량을 부여할 수있음을 확인하였다. 방사선조사로 인한 폐의 정상조직합병증확률과 종양 반대편 폐의 등가균일선량 측면에서는 토모테라피가 기존 선형가속기보다 상대적으로 더 우수한 결과를 보였으나, 종양 내 치료선량 분포의 균일도에서는 기존 선형 가속기가 더 양호한 결과를 보였다. 치료 빔 전달 시간측면에서는 토모테라피가 기존 선형가속기 경우보다 2배 이상의 시간이 소요되었다. 이와 같은 본 연구의 결과 분석을 통해 폐종양 부위의 움직임이 적은 경우, 환자의 상태와 선량분포의 적합성 등을 고려한 최적의 치료계획을 세운다면 토모테라피를 사용하는 방사선 수술이 유효성 및 타당성이 있음을 확인할 수 있었다.