• Title/Summary/Keyword: radiation exposure

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Comparison of Skin Injury Induced by β- and γ-irradiation in the Minipig Model

  • Kim, Joong-Sun;Jang, Hyosun;Bae, Min-Ji;Shim, Sehwan;Jang, Won-Seok;Lee, Sun-Joo;Park, Sunhoo;Lee, Seung-Sook
    • Journal of Radiation Protection and Research
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    • v.42 no.4
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    • pp.189-196
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    • 2017
  • Background: The effects of radiation on tissues vary depending on the radiation type. In this study, a minipig model was used to compare the effects of ${\beta}$-rays from $^{166}Ho$ and ${\gamma}$-rays from $^{60}Co$ on the skin. Materials and Methods: In this study, the detrimental effects of ${\beta}$- and ${\gamma}$-irradiation on the skin were assessed in minipigs. The histopathological changes in the skin from 1 to 12 weeks after exposure to 50 Gy of either ${\beta}$- (using $^{166}Ho$ patches) or ${\gamma}$- (using $^{60}Co$) irradiation were assessed. Results and Discussion: The skin irradiated by ${\beta}$-rays was shown to exhibit more severe skin injury than that irradiated by ${\gamma}$-rays at 1-3 weeks post-exposure; however, while the skin lesions caused by ${\beta}$-rays recovered after 8 weeks, the ${\gamma}$-irradiated skin lesions were not repaired after this time. The observed histopathological changes corresponded with gross appearance scores. Seven days post-irradiation, apoptotic cells in the basal layer were detected more frequently in ${\beta}$-irradiated skin than in ${\gamma}$-irradiated skin. The basal cell density and skin thickness gradually decreased until 4 weeks after ${\gamma}$- and ${\beta}$- irradiation. In ${\beta}$-irradiated skin lesions, and the density and thickness increased sharply back to control levels by 6-9 weeks. However, this was not the case in ${\gamma}$-irradiated skin lesions. In ${\gamma}$-irradiated skin, cyclooxygenase-2 (COX-2) was shown to be expressed in the epidermis, endothelial cells of vessels, and fibroblasts, while ${\beta}$-irradiated lesions exhibited COX-2 expression that was mostly limited to the epidermis. Conclusion: In this study, ${\beta}$-rays were shown to induce more severe skin injury than ${\gamma}$-rays; however, the ${\beta}$-rays-induced injury was largely repaired over time, while the ${\gamma}$-rays-induced injury was not repaired and instead progressed to necrosis. These findings reveal the differential effects of ${\gamma}$- and ${\beta}$-irradiation on skin and demonstrate the use of minipigs as a beneficial experimental model for studying irradiation-induced skin damage.

Monitoring Method for an Ambient Gamma Exposure Rate and Its Measurement Analysis

  • Lee, Mo-Sung;Woo, Jong-Kwan
    • Journal of Radiation Protection and Research
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    • v.31 no.4
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    • pp.197-201
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    • 2006
  • Daily and seasonal variations of the ambient gamma ray exposure rates were measured by using a pressurized ion chamber from January 2003 to December 2005 in the CheongJu Regional Radiation Monitoring Post and the patterns of the distributions were studied. The annual average of the daily variation of the exposure rate was $\sim0.17{\mu}R/h$. The exposure rate was found to be maximum during 8:00 am to 9:00 am and minimum during 8:00 pm to 10:00 pm. For the annual data, the exposure rate was the minimum during the month of February. The exposure rate increased from February to mid-October (except during the period from May to July with no change) and decreased from October to February. The seasonal variation was found to be about $1{\mu}R/h$. Most of the measured values (96%) of the exposure rates fell under the normal distribution with a deviation of less than 4.8% and the remaining 4% had large fluctuations caused mainly by the rainfalls.

Changes in Exposure Dose and Image Quality due to Radiation Shielding in Pediatric Patients (소아 환자에서 방사선 차폐체로 인한 피폭선량과 화질의 변화)

  • Lee, Young-Hee;Lee, Yong-Ki
    • Journal of the Korean Society of Radiology
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    • v.14 no.7
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    • pp.931-936
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    • 2020
  • This study was conducted to observe the changes in radiation exposure dose and image quality of pediatric patients according to the presence and size of the gonadal shield when using the AEC system. X-ray equipment was used to measure the radiation exposure dose in the abdominal and gonads of the pediatric phantom when no shielding body was used and when three different sizes of shielding body were used, and SNR and CNR were measured through the obtained images. As a result of the study, the radiation exposure dose to the gonads decreased in proportion to the size of the radiation shield, but the radiation exposure dose to the abdomen was rather increased, and the image quality did not change. It is recommended to use a shield with a size optimized for the age, weight, and body size of the pediatric patient so as not to be overexposed by the increased radiation due to the radiation shield due to the use of the AEC System. For this purpose, information about the pediatric patient with the nurse It is believed that exchange is necessary.

A Study on Perceptions by College Students of Radiology about the Knowledge, Attitudes and Behaviors of Radiation Exposure Management (방사선과 대학생이 방사선피폭관리에 대한 지식, 태도, 행위에 관한 연구)

  • Yeo, Jindong;Ko, Inho;Kim, Hye-Sook
    • Journal of the Korean Society of Radiology
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    • v.9 no.2
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    • pp.79-99
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    • 2015
  • Participants of this study were students of radiology who were attending colleges or universities located in Daegu and Gyeongbuk. This researcher conducted a questionnaire survey of those students from Feb. 3rd to 21st, 2014. The findings of the study can be summarized as follows. 1. Concerning the knowledge of radiation exposure management, the respondents' scores were highest in two items, or 'Materials based on lead or concrete may shield X-rays' and 'The sexual gland is very sensitive to radiation' and lowest in the item which says' 'Occupational radiation exposure dose should not exceed 20mSv a year in average on a 5-year period basis'. 2. The participants' scores for the attitudes of radiation exposure management were higher in two items, or 'Health examination should be made regularly in relation to radiation exposure' and 'Those who work within the area of irradiation should wear protective clothes' and lowest in the item which says 'Radiation exposure dose should be regularly measured for the calibration of the radiation system'. 3. For the behaviors of radiation exposure management, the surveyed students showed highest scores in two items, or 'When irradiating the patient, the radiator should be behind the protective barrier(plate)' and 'It is needed to receive the education of radiation exposure management regularly' While, their score for a behavior described in the item saying 'Before using the radiation system, it is needed to check whether the machine works normally.

A Study on Quality Control for Medical Image by Using Deviation Index of Digital Radiology (디지털 방사선 영상의 편차지수를 이용한 의료영상 품질관리에 관한 연구)

  • Jeong, Hoi-Woun;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.43 no.2
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    • pp.115-121
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    • 2020
  • In a digital radiation system using a Flat Panel Detector, we attempted to the quality control of digital radiography system using the Exposure Index and Deviation Index. Calibration was performed with the radiation quality suggested by the International Electrotechnical Commission, and through an experiment using a phantom, appropriate inspection radiation conditions applicable to medical institutions were selected. The study was conducted using the selected radiation conditions. Through those chest posterior anterior image, information such as examination conditions and exposure index was obtained. The deviation index was derived by analyzing the exposure index based on the target exposure index calculated by the phantom study. As for the analyzed exposure index, 97.1% was distributed within the range of ± 2.0 based on the deviation index. Quality control of medical images should be performed through management of inspection conditions through exposure index and deviation index and management of medical images.

A Study on the Isodose Distribution in a Vascular Characterization Room

  • Choi, Young;Kang, Byung-Sam;Min, Jung-Whan
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.1
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    • pp.7-11
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    • 2011
  • As applications of radiation grow wider from use in the early detection of lesions and preventive diagnosis purposes to the treatment of diseases, the possibilities for patients and working professionals to be exposed to radiation are becoming greater than ever. This can not only directly bring about an increase in patient's individual radiation exposure, but also brings about an increase in the annual radiation dose of working professionals. Therefore, research and countermeasures to reduce radiation dosage are required. In this study, space dosimetry has been divided into two separate measuments with an understanding of the increasing number of angiography procedures: front perspective and side perspective. According to the results of the isodose curve, a way to minimize radiation exposure in working professionals has been suggested. This was made possible by workers through awareness of suitable working positions.

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Determination of Consistency according to the Status of Supplementary Education for Radiation Safety Management Managers (방사선안전관리책임자 보수교육의 현황에 따른 정합성 판단)

  • Seung-Chul Kim
    • Journal of radiological science and technology
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    • v.47 no.1
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    • pp.7-12
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    • 2024
  • Medical institutions wishing to install and operate diagnostic radiation generators must complete appointment training within one year of appointment based on the 「Medical Act」 and the 「Rules on Safety Management of Diagnostic Radiation Generator Devices」 which will come into effect on January 1, 2024. Additionally, You must receive supplementary education every three years from the date you received it. The strengthening of safety management for diagnostic radiation generators used in medical institutions means that although the radiation exposure that may occur when using diagnostic radiation generators is low, the risk of carcinogenesis may be higher than previously evaluated. In addition, safety management of diagnostic radiation generators can be said to be an essential requirement because it has been reported that the incidence of leukemia and other diseases is increasing in diagnostic radiation tests. However, the safety management training targets and programs for radiation exposure management operated by other organizations other than diagnostic radiation generators are significantly different. In addition, since the public institutions that are responsible for radiation safety management are divided, there is a risk of duplicative, excessive, and under-administrative application to medical institutions and educational institutions that install and operate diagnostic radiation generators. Therefore, we would like to determine their consistency by comparing domestic and foreign related cases and the provisions of the 「Medical Act」 and the 「Nuclear Safety Act」.

X-Rays through the Looking Glass: Mobile Imaging Dosimetry and Image Quality of Suspected COVID-19 Patients

  • Schelleman, Alexandra;Boyd, Chris
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.120-126
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    • 2021
  • Background: This paper aims to evaluate the clinical utility and radiation dosimetry, for the mobile X-ray imaging of patients with known or suspected infectious diseases, through the window of an isolation room. The suitability of this technique for imaging coronavirus disease 2019 (COVID-19) patients is of particular focus here, although it is expected to have equal relevance to many infectious respiratory disease outbreaks. Materials and Methods: Two exposure levels were examined, a "typical" mobile exposure of 100 kVp/1.6 mAs and a "high" exposure of 120 kVp/5 mAs. Exposures of an anthropomorphic phantom were made, with and without a glass window present in the beam. The resultant phantom images were provided to experienced radiographers for image quality evaluation, using a Likert scale to rate the anatomical structure visibility. Results and Discussion: The incident air kerma doubled using the high exposure technique, from 29.47 µGy to 67.82 µGy and scattered radiation inside and outside the room increased. Despite an increase in beam energy, high exposure technique images received higher image quality scores than images acquired using lower exposure settings. Conclusion: Increased scattered radiation was very low and can be further mitigated by ensuring surrounding staff are appropriately distanced from both the patient and X-ray tube. Although an increase in incident air kerma was observed, practical advantages in infection control and personal protective equipment conservation were identified. Sites are encouraged to consider the use of this technique where appropriate, following the completion of standard justification practices.

Neurobehavioural Changes and Brain Oxidative Stress Induced by Acute Exposure to GSM900 Mobile Phone Radiations in Zebrafish (Danio rerio)

  • Nirwane, Abhijit;Sridhar, Vinay;Majumdar, Anuradha
    • Toxicological Research
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    • v.32 no.2
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    • pp.123-132
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    • 2016
  • The impact of mobile phone (MP) radiation on the brain is of specific interest to the scientific community and warrants investigations, as MP is held close to the head. Studies on humans and rodents revealed hazards MP radiation associated such as brain tumors, impairment in cognition, hearing etc. Melatonin (MT) is an important modulator of CNS functioning and is a neural antioxidant hormone. Zebrafish has emerged as a popular model organism for CNS studies. Herein, we evaluated the impact of GSM900MP (GSM900MP) radiation exposure daily for 1 hr for 14 days with the SAR of 1.34W/Kg on neurobehavioral and oxidative stress parameters in zebrafish. Our study revealed that, GSM900MP radiation exposure, significantly decreased time spent near social stimulus zone and increased total distance travelled, in social interaction test. In the novel tank dive test, the GSM900MP radiation exposure elicited anxiety as revealed by significantly increased time spent in bottom half; freezing bouts and duration and decreased distance travelled, average velocity, and number of entries to upper half of the tank. Exposed zebrafish spent less time in the novel arm of the Y-Maze, corroborating significant impairment in learning as compared to the control group. Exposure decreased superoxide dismutase (SOD), catalase (CAT) activities whereas, increased levels of reduced glutathione (GSH) and lipid peroxidation (LPO) was encountered showing compromised antioxidant defense. Treatment with MT significantly reversed the above neurobehavioral and oxidative derangements induced by GSM900MP radiation exposure. This study traced GSM900MP radiation exposure induced neurobehavioral aberrations and alterations in brain oxidative status. Furthermore, MT proved to be a promising therapeutic candidate in ameliorating such outcomes in zebrafish.

Assessment of radiation exposure from cesium-137 contaminated roads for epidemiological studies in Seoul, Korea

  • Lee, Yun-Keun;Ju, Young-Su;Lee, Won Jin;Hwang, Seung Sik;Yim, Sang-Hyuk;Yoo, Sang-Chul;Lee, Jieon;Choi, Kyung-Hwa;Burm, Eunae;Ha, Mina
    • Environmental Analysis Health and Toxicology
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    • v.30
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    • pp.5.1-5.8
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    • 2015
  • Objectives We aimed to assess the radiation exposure for epidemiologic investigation in residents exposed to radiation from roads that were accidentally found to be contaminated with radioactive cesium-137 ($^{137}Cs$) in Seoul. Methods Using information regarding the frequency and duration of passing via the $^{137}Cs$ contaminated roads or residing/working near the roads from the questionnaires that were obtained from 8875 residents and the measured radiation doses reported by the Nuclear Safety and Security Commission, we calculated the total cumulative dose of radiation exposure for each person. Results Sixty-three percent of the residents who responded to the questionnaire were considered as ever-exposed and 1% of them had a total cumulative dose of more than 10 mSv. The mean (minimum, maximum) duration of radiation exposure was 4.75 years (0.08, 11.98) and the geometric mean (minimum, maximum) of the total cumulative dose was 0.049 mSv (<0.001, 35.35) in the exposed. Conclusions An individual exposure assessment was performed for an epidemiological study to estimate the health risk among residents living in the vicinity of $^{137}Cs$ contaminated roads. The average exposure dose in the exposed people was less than 5% of the current guideline.