• Title/Summary/Keyword: radiation effect

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Simple Calculation Method as a Supplementary Radiation Safety Assessment for Facility with Radiation Generator

  • Kim, Sang-Tae
    • International Journal of Contents
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    • v.14 no.4
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    • pp.65-69
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    • 2018
  • The objective of this study was to conduct a radiation shielding analysis for the facility equipped with radiation generator. The analysis was carried out in two aspects. First, from the aspect of the effect caused by primary and leakage radiation. Second, effect of scattered radiation was evaluated by applying a simple calculation method based on a scattering rate concept since effect of scattered radiation is significantly important at maze entrance of the radiation facility. The calculated results obtained using the simple method were compared to the results calculated using Geant4 code and the measured values. The results calculated by the suggested method indicate that slight error exists in a radiation shielding analysis done at the maze entrance comparing to other two results, while the results evaluated at the outside of the maze entrance door are relatively consistent with other values.

Effect of Radiation Therapy on Voice Parameters in Early Glottic Cancer and Normal Larynx (방사선 요법이 초기 성대암 및 정상 후두의 음성 지표에 미치는 영향)

  • 김민식;박한종;선동일;박영학;조승호
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.7 no.1
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    • pp.32-38
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    • 1996
  • The preservation of the voice-producing mechanism is an important feature in the management of laryngeal cancer by radiotherapy. But, radiation therapy has certain side effects such as mucositis, tissue edema, necrosis and fibrosis which could effect on normal voice production. Several subjective studies that used questionnaires and auditory perceptual judgements of voice have been interpreted to mean that radiation results in a normal or near-normal voice. Objective evidence of the status of vocal function after radiation treatment, however, is still lacking. We analyzed the changes that occur in voice parameters in a group of patients undergoing radiation therapy, in order to determine the effect of radiation on voice quality. In this study acoustic, aerodynamic measures of vocal function were used to determine the characteristics of voice production. We found that voice parameters in early glottic cancer changed meaningfully comparing to normal larynx with or without radiation and radiation therapy has an little effect on normal larynx.

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Effect of ${\gamma}-ray$ Irradiation on the Activities of Monoamine Oxidase in Rat Brain and Liver (방사선 조사가 쥐의 뇌와 간의 Monoamine Oxidase 활성도에 미치는 영향)

  • Kim, Joo-Young;Choi, Myung-Sun;Choi, Myung-Un
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.205-217
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    • 1993
  • In order to evalute the effects of radiation on mammalian neuronal system, we have examined the effect of gamma-ray radiation on the monoamine oxidase (MAO) activity in monoaminergic neurons. Following the whole body irradiation, MAO activity in the rat brain was measured as well as in the liver for the comparative studies between the neuronal and nonneuronal system. The effects of some radiation protectors and sensitizers were also examined in addition to the $O_2$ effect. The results can be summarized as follows. 1) The MAO activity of rat brain was minimally affected by the radiation dose up to 1,700 cGy Radiation dose above 2,500 cGy inhibited the brain MAO activity by no less than $l0\%.$ MAO-A form was found to be particularly sensitive to radiation. The liver MAO was somewhat inhibited (by about $5\%$) but hardly dependent on the dose of radiation. 2) The inhibitory effect on the brain was initiated immediately by the radiation dose of 2,500 cGy. On the contrary, for the liver, the inhibitory effect became apparent only 2 days after irradiation. 3) Two days after a dose of 2,500 cGy, Vmax and Km of the brain mitochondrial MAO decreased. For liver, Vmax decreased while Km increased, which indicates the kinetic patterns for the neuronal and nonneruronal systems are not affected similarly by radiation. 4) The effect of several known radiation protectors and sensitizers on MAO activity was tested ut no definite results were obtained. The level of -SH group increased in some degree upon radiation but not by the compounds. 5) MAO activity was not affected by $O_2$ concentration, while an elevated level of lipid peroxidase was found under the same condition. The results described here indicate that characteristics of MAO, one of the most important central nervous system enzymes, are liable to radiation, which is partially differentiated from the liver MAO. Also indicated are that the -SH groups are hardly related to the effect of radiation but the production of the lipid peroxide seems to be somewhat correlated to the effect of radiation.

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Ionizing Radiation Sensitivity Analysis of the Structural Characteristic for the MOS Capacitors (MOS 커패시터의 구조별 전리방사선 감도 특성 분석)

  • Hwang, Young-Gwan;Lee, Seung-Min
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.7
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    • pp.963-968
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    • 2013
  • Ionizing Radiation effects on MOS devices provide useful information regarding the behavior of MOS based devices and circuits in the electronic instrumentation parts and instructive data for making the high sensitive sensors. The study presents the results of the analysis on the structural characteristics of MOS capacitor for sensing the ionizing radiation effect. We performed numerical modeling of Ionizing-radiation effect on MOS capacitor and simulation using Matlab program. Also we produced MOS capacitors and obtained useful data through radiation experiment to analyse the characteristic of ionizing radiation effect on MOS capacitor. Increasing the thickness of MOS capacitor's oxide layer enhanced the sensitivity of MOS capacitor under irradiation condition, but the sensitivity of irradiated MOS capacitor is uninfluenced by the area of MOS capacitor. The high frequency capacitance of the MOS capacitor is found to be strongly affected by incident ionizing radiation.