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Respiratory Effort Monitoring Using Pulse Transit Time in Human (인체에서 맥파전달시간을 이용한 호흡노력 모니터링)

  • 정동근
    • Journal of Biomedical Engineering Research
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    • v.23 no.6
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    • pp.485-489
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    • 2002
  • In this study. respiratory efforts were monitored by the change of pulse transit time (PTT) which is related with the arterial pressure PTT is the time interval between the peak of R wave in ECG and the maximal slope point of photoplethysmogram(PPG). Biosignals, ECG and finger photoplethysmogram(PPG), were converted to digital data, and PTT was evaluated in personal computer with every heart beat. Results were presented as a graph using spline interpolation. The software was implemented in C$\^$++/ as a window-based application program. PTT was periodically changed according to airflow in resting respiration. In the resting respiration, PTT was changed according to the respiratory cycle. The amplitude of PTT fluctuation was increased by deep respiration, and increased by partial airway obstruction. These results suggest that PTT is responsible to respiratory effort which could be evaluated by the pattern of PTT change. And it is expected that PTT could be applied in the monitoring of respiratory effort by noninvasive methods, and is very useful method for the evaluation of respiratory distress.

A Study on the Properties of Two-Component Type Polyurethane Resins Mixing Polyol and 4,4'-diphenyl Methane Diisocynate (폴리올(polyol)과 4,4'-디페닐메탄디이소시아네이트(MDI)를 혼합한 2액형 폴리우레탄 수지의 물성에 관한 연구)

  • Lee, Bum-Chuli;Choi, Sang-Goo
    • Elastomers and Composites
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    • v.36 no.4
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    • pp.268-277
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    • 2001
  • The MDI(4,4'-diphenyl methane diisocyanate) was mixed with PPG, PEG and trimethylolpropane(TMP) respectively to prepare polyurethane resin. The various physical properties were measured for the mixtures. The gel-time was shortened by adding of PEG and TMP The molecular weight made a greater influence on the gel-time than the number of functional groups. The NCO-OH reaction was more active and faster than the NCO-NCO reaction. The hardness was influenced by crosslinking-density and molecular structure. The NCO-OH reactions yielded the flexible films and the NCO-NCO reactions yielded the brittle films. The increase of crystallinity and shrinkage induced the low adhesion ratio but the adding of TMP induced the high adhesion ratio. The flame-retardancy was influenced by quantity and kinds of flame-retardant. IXOL B-251 was the most excellent among the flame-retardants employed in this study. TCCP was partially separated because of the lack of solubility.

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Synthesis and Surface Properties of Fluorinated Polyurethanes (불소화된 폴리우레탄의 합성과 표면특성)

  • Kim, Hyung-Joong
    • Polymer(Korea)
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    • v.25 no.1
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    • pp.33-40
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    • 2001
  • Fluorinated polyurethane elastomers were synthesized by two step polyaddition of a perfluorinated polyether diol(trade name of Fomblin $ZDOL^{\circledR}$) and diisocyanates such as 4,4'-diphenyl methane diisocyanate(MDI) and toluene 2,4-diisocyanate(TDI). In order to control the Fomblin moiety of the soft segment in the synthesized elastomers to 10~50%, polyether type polyols such as polypropylene glycol(PPG) and polytetramethylene glycol(PTMG) were mixed during the polymerization reaction. Ethylene diamine or 1,4-butane diol was used as chain extenders. The structure and average molecular weight of the produced polyurethanes were confirmed by using FT-IR, $^1H-NMR$, DSC, and GPC. The surface properties were analyzed by using X-ray photoelectron spectroscopy(XPS) and contact angle meter. From the results of the surface analysis it was concluded that the fluorine groups were localized on the surface rather than the inside of the polyurethane films.

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Development of a Classification Model for Driver's Drowsiness and Waking Status Using Heart Rate Variability and Respiratory Features

  • Kim, Sungho;Choi, Booyong;Cho, Taehwan;Lee, Yongkyun;Koo, Hyojin;Kim, Dongsoo
    • Journal of the Ergonomics Society of Korea
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    • v.35 no.5
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    • pp.371-381
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    • 2016
  • Objective:This study aims to evaluate the features of heart rate variability (HRV) and respiratory signals as indices for a driver's drowsiness and waking status in order to develop the classification model for a driver's drowsiness and waking status using those features. Background: Driver's drowsiness is one of the major causal factors for traffic accidents. This study hypothesized that the application of combined bio-signals to monitor the alertness level of drivers would improve the effectiveness of the classification techniques of driver's drowsiness. Method: The features of three heart rate variability (HRV) measurements including low frequency (LF), high frequency (HF), and LF/HF ratio and two respiratory measurements including peak and rate were acquired by the monotonous car driving simulation experiments using the photoplethysmogram (PPG) and respiration sensors. The experiments were repeated a total of 50 times on five healthy male participants in their 20s to 50s. The classification model was developed by selecting the optimal measurements, applying a binary logistic regression method and performing 3-fold cross validation. Results: The power of LF, HF, and LF/HF ratio, and the respiration peak of drowsiness status were reduced by 38%, 22%, 31%, and 7%, compared to those of waking status, while respiration rate was increased by 3%. The classification sensitivity of the model using both HRV and respiratory features (91.4%) was improved, compared to that of the model using only HRV feature (89.8%) and that using only respiratory feature (83.6%). Conclusion: This study suggests that the classification of driver's drowsiness and waking status may be improved by utilizing a combination of HRV and respiratory features. Application: The results of this study can be applied to the development of driver's drowsiness prevention systems.

A photoplythsmography starting point detection algorithm for pulse wave velocity (맥파속도 측정을 위한 PPG 기시점 검출알고리즘)

  • Jeong, Seokhoon;Ko, Kuk Won;Lee, Sangjoon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2015.10a
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    • pp.949-951
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    • 2015
  • 본 연구는 맥파속도를 측정 하는데 간단한 방법으로 1채널 심전도 데이터와 4채널 광전식 용적맥파를 이용하여 취득한 데이터를 분석하는 알고리즘을 제안한다. 심전도의 R 피크점과 좌우 지첨, 족첨에서 발생하는 4 채널 맥파신호간 시간차를 이용하여 맥파 전달시간을 구하고 팔, 다리 길이로 나눠서 맥파전달속도를 구한다. 알고리즘은 심전도 R 피크점 검출, 4 채널 맥파에서의 피크점 검출 이후 검출된 피크정보를 이용하여 맥파의 시작지점인 기시점을 검출하는 간단한 방법을 개발하였고, 4 가지 맥파형태에 검출알고리즘을 적용하여 검증 하였다. 본 연구에서 개발한 방법으로 간단히 맥파속도를 측정하여 동맥경화나 고혈압, 당뇨 등 심혈관 관련 연구의 기반이 될 수 있을 것으로 사료된다.

Preparation of Cellulose Nanoparticles Loaded with Retinyl Palmitate (레티닐 팔미테이트가 봉입된 셀룰로오스 나노입자의 제조)

  • Lee, Jeong-Soon;Ma, Sang-Chol;Kang, Ki-Choon;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.34 no.3
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    • pp.175-181
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    • 2008
  • Cellolose nanoparticles loaded with retinyl palmitate were prepared by modified spontaneous emulsification solvent diffusion method. We used polysorbate 20, polysorbate 60, and PPG-26-Buteth-26/PEG-40 Hydrogenated castor oil as dispersion medium. The optimum condition for particle size of cellulose nanoparticles was 1w/v% ethyl cellulose with, 3w/v% polysorbate 60 solution. And The optimum condition for leading amount of retinyl palmitate of cellulose nanoparticles was 2w/v% ethyl cellulose with 1w/v% polysorbate 60 solution. Also, we found that this optimum condition can be applicable to other active compounds.

A Study on Estimation of Carotid Intima-Media Thickness(IMT) using Pulse Wave Velocity(PWV) (맥파전달속도를 이용한 내중막 두께 추정에 관한 연구)

  • Song, Sang-Ha;Jang, Seung-Jin;Kim, Wuon-Shik;Lee, Hyun-Sook;Yoon, Young-Ro
    • Journal of Biomedical Engineering Research
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    • v.30 no.5
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    • pp.401-411
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    • 2009
  • In this paper, we correct pulse wave velocity(PWV) with heart-rate and derive regression equations to estimate intima-media thickness(IMT). Widely used methods for diagnosis of arteriosclerosis are IMT and PWV. Arterial wall stiffness determines the degree of energy absorbed by the elastic aorta and its recoil in diastole but there is not correlation between sclerosis and IMT in an existing study. In this study, we will correct PWV with heart-rate and get regression equation to estimate IMT using heart-rate correction index(HCI). We executed experiments for this study. Made up question of physical condition and measured electrocardiogram(ECG), photoplethysmogram (PPG) of finger-tip and toe-tip and ultrasound image of carotid artery. Calculated PWV and IMT using ECG, PPG and ultrasound image. We found that every p-value between PWV and IMT is not significant(<0.05). But p-value between IMT and HCI which is a corrected PWV using heart-rate is significant(>0.01). We use HCI and various measured parameter for estimating regression equation and apply backward estimation to select parameters for regression analysis. Result of backward estimation, found that only HCI is possible to derive proper regression equation of IMT. Relationship between PWV and IMT is the second order. Result of regression equation of E-H PWV is $R^2$=0.735, adj $R^2$=0.711. This is the best correlation value. We calculate error of its analysis for verification of earlobe PWV regression equation. Its result is RMSEP=0.0328, MAPE(%) = 4.7622. Like this regression analysis, we know that HCI is useful parameter and relationship between PWV, HCI and IMT. In addition, we are able to suggest possibility which is that we can get different parameter of prediction throughout just one measurement.

Automotive Pre-primed Coatings with Automotive Structural Adhesive for Non-weldable Binding Process (자동차 구조용 접착제를 이용한 자동차용 Pre-primed 도료의 비용접식 접합공정 적용)

  • Moon, Je-Ik;Lee, Yong-Hee;Kim, Hyun-Joong;Noh, Seung Man;Nam, Joon Hyun;Kim, Min-Su;Kim, Jun-Ki;Kim, Jong-Hoon
    • Journal of Adhesion and Interface
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    • v.12 no.3
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    • pp.99-104
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    • 2011
  • Currently, automotive pre-primed coatings has been developed to overcome environmental regulations and to reduce manufacturing cost in automotive industry. By these reasons, an automotive pre-primed system has been investigated to remove the wash and pre-treatment process using a roll coating application. It is required to develop non-weldable pre-primed system for automotive structural adhesives, because pre-primed sheet coated with organic compounds is hard to be assembled by welding process. Primer 1 (polyester type) and primer 2 (urethane type) were designed to satisfy flexibility and formability for non-weldable pre-primed system. According to the results of physical property test of the primers, adhesion test such as single-lap shear test and T-peel test, primer 1 (polyester type) had better physical properties such as pencil hardness, solvent resistance, flexibility and adhesion with automotive adhesive than that of primer 2 (polyurethane type). In addition, the possibility of the non-weldable pre-primed system was applicable to automotive assembly process in place of welding process.

Implementation of PTT Change Monitoring System According to Exercise Intensity (PTT기반 운동 강도 모니터링 시스템 구현)

  • Lee, Ji-Su;Kim, Dong-Chan;Lee, Gyeong-Tack;Kim, Gyeong-Seop;Noh, Yun-Hong;Jeong, Do-Un
    • Journal of the Institute of Convergence Signal Processing
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    • v.21 no.1
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    • pp.49-54
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    • 2020
  • Cardiovascular disease is the leading cause of death worldwide and is caused by a variety of causes. The highest risk factor for cardiovascular disease is high blood pressure, which has no obvious symptoms, but if left untreated, it causes several complications. In order to treat hypertension, medication and regular exercise are required. In people with high blood pressure, excessive physical activity can put a great strain on the heart and lead to cardiovascular disease. Therefore, there is a need for an exercise intensity monitoring system through PTT measurement that can perform exercise at an appropriate intensity. In this study, we implemented a PTT change monitoring system according to exercise intensity by calculating PTT through ECG and PPG measurement. The implemented system differentiates the R-peak of the ECG and P-peak of the PPG, and calculates the PTT using the time difference between R-peak and P-peak. A running experiment was conducted to monitoring PTT change according to exercise intensity. As a result of the experiment, low intensity PTT is 0.313s, moderate is 0.220s, high is 0.188s, it was confirmed that the PTT decreased as the exercise increase increased.

Effect of Ferro-cement retrofit in the stiffened infill RC frame

  • Arulselvan, Suyamburaja;Sathiaseelan, P.
    • Structural Engineering and Mechanics
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    • v.61 no.4
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    • pp.511-518
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    • 2017
  • This paper presents an experimental investigation on the contribution of RCC strip in the in-filled RC frames. In this research, two frames were tested to study the behavior of retrofitted RC frame under cyclic loading. In the two frame, one was three bay four storey R.C frame with central bay brick infill with RCC strip in-between brick layers and the other was retrofitted frame with same stiffened brick work. Effective rehabilitation is required some times to strengthened the RC frames. Ferrocement concrete strengthening was used to retrofit the frame after the frame was partially collapsed. The main effects of the frames were investigated in terms of displacement, stiffness, ductility and energy dissipation capacity. Diagonal cracks in the infill bays were entirely eliminated by introducing two monolithic RCC strips. Thus more stability of the frame was obtained by providing RCC strips in the infill bays. Load carrying capacity of the frame was increased by enlarging the section in the retrofitted area.