• Title/Summary/Keyword: r-closure

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Effect of Epidermal Growth Factor on Full Thickness Skin Defects of the Inoperable Patients (수술적 치료가 불가능한 환자의 전층 피부결손에 대한 표피성장인자의 유용성)

  • Lee, Jong Hoon;Lee, Young Jong;Hong, Sung Hee;Kim, Jun Pyo
    • Archives of Plastic Surgery
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    • v.32 no.3
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    • pp.314-318
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    • 2005
  • For treatment of full thickness skin defects caused by trauma or infections, skin grafts or flaps have been the treatment of choice to date. However, in patients who are not candidates for surgery, either due to his general conditions or refusal to receive treatment, supportive methods have been the only means of care, which inherently caused psychological trauma to the patient due to uncertainties of ultimate outcome and the length of treatment. This study aimed to heal full thickness skin defects through application of topical epidermal growth factor in patients who have received 2 to 3 weeks of conservative management using medifoam $B^{(R)}$ without improvement. Six patients from March 2002 to July 2004 were enrolled. The mean size of defects was $5.4{\times}4.6cm$ in 4 patients with carcinoma and $6.4{\times}4.1cm$ in 2 patients with osmidrosis. Commercially available 0.005% EGFR solution was used, and dressing was performed once daily. All patients benefitted from the use of EGF, with closure of skin defects taking an average of 28 days in cancer patients and 22.5 days in osmidrosis cases. EGF can be used as a supportive mean of treatment in the inoperable patients with skin defects, with resultant hastening of healing shortening duration of treatment.

Fatigue Crack Propagation Characteristics in SA 516-70 Steel for Pressure Vessels at Low Temperature (SA 516-70 압력용기용강의 저온피로 크랙전파 특성에 관한 연구)

  • Park, K.D.;Cha, S.S.
    • Journal of Power System Engineering
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    • v.3 no.2
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    • pp.51-56
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    • 1999
  • Fatigue crack propagation rates and characteristics of the SA516-70 steel which is used for the low temperature pressure vessels, were studied in the room temperature of $10^{\circ}C$ and low temperature ranges of $-10^{\circ}C,\;-30^{\circ}C,\;-50^{\circ}C,\;and\;-70^{\circ}C$ with stress ratio of R=0.05. The obtained experimental results are as follows; 1) In the logarithmic relationship between the fatigue crack propagation rate(da/dN) and stress intensity factor K, the linear relationship was obtained up to da/dN > $8{\times}10^3$ mm/cycle in the same of room temperature, but in low temperature case, the relationship was extended to the range of low crack propagation rate. 2) The lower limit stress intensity factor of SA516-70 ${\Delta}K_{th}\;was\;23MPa\sqrt{m}$ and in the case of low temperature $-50^{\circ}C\;and\;-70^{\circ}C$, the crack propagation rate da/dN which showed a linear relation, reached rapidly to the ${\Delta}K_{th}$. As the results, the crack propagation rates of $-50^{\circ}C\;and\;-70^{\circ}C$ were lower than that of room temperature and according to the testing temperature the rates were decreased rapidly to the ${\Delta}K_{th}$. 3) On the relationship between the stress intensity factor ${\Delta}K$ and the track propagation cycle, the stress intensity factors of low cycle region was rapidly increased at low temperature, but ${\Delta}K$ was increased rapidly at room temperature of high cycle. 4) On the relationship between the fatigue crack propagation rate and cycle, the fatigue crack propagation rate showed higher gradient in the room temperature than the low temperature due to the increment in ductility at low temperature.

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Fatigue Crack Propagation Characteristics in ASTM 516/60 Steel at Low Temperature (ASTM 516-60 강의 저온피로 크랙전파 특성에 관한 연구)

  • 박경동;김정호
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2000.10a
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    • pp.240-245
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    • 2000
  • Fatigue crack propagation rates and characteristics of the SA516-60 steel which is used for the low temperature pressure vessels, were studied in the room temperature of $25^{\circ}C$ and low temperature ranges of $10^{\circ}C,\; -10^{\circ}C,\; -30^{\circ}C,\; -50^{\circ}C, \;and\; -70^{\circ}C4 with stress ratio of R=0.05. The obtained experimental results are as follows; 1) In the logarithmic relationship between the fatigue crack propagation rate(da/dN) and stress intensity factor K, the linear relationship was obtained up to da/dN 〉$8\times10^{-3}$/mm/cycle in the same of room temperature, but in low temperature case, the relationship was extended to the range of crack propagation rate. 2) The lower limit stress intensity factor of SA516-60 $\DeltaK_{th}$ was 15.8MPa and in the case of low temperature $-50^{\circ}C\; and\; -70^{\circ}C$, the crack propagation rate da/dN which showed a linear relation, reached rapidly to the $\DeltaK_{th}$/. As the results, the crack propagation rates of $-50^{\circ}C\; and\; -70^{\circ}C$ were lower than that of room temperature and according to the testing temperature the rates were decreased rapidly to the $\DeltaK_{th}$/. 3) On the relationship between the stress intensity factor $\DeltaK$ and the crack propagation cycle, the stress intensity factors of low cycle region was rapidly increased at low temperature, but $\DeltaK$ was increased rapidly at room temperature of high cycle. 4) On the relationship between the fatigue crack propagation rate and cycle, the fatigue crack propagation rate showed higher gradient in the room temperature than the low temperature due to the increment in ductility at low temperature.

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Unsteady Flow with Cavitation in Viscoelastic Pipes

  • Soares, Alexandre K.;Covas, Didia I.C.;Ramos, Helena M.;Reis, Luisa Fernanda R.
    • International Journal of Fluid Machinery and Systems
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    • v.2 no.4
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    • pp.269-277
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    • 2009
  • The current paper focuses on the analysis of transient cavitating flow in pressurised polyethylene pipes, which are characterized by viscoelastic rheological behaviour. A hydraulic transient solver that describes fluid transients in plastic pipes has been developed. This solver incorporates the description of dynamic effects related to the energy dissipation (unsteady friction), the rheological mechanical behaviour of the viscoelastic pipe and the cavitating pipe flow. The Discrete Vapour Cavity Model (DVCM) and the Discrete Gas Cavity Model (DGCM) have been used to describe transient cavitating flow. Such models assume that discrete air cavities are formed in fixed sections of the pipeline and consider a constant wave speed in pipe reaches between these cavities. The cavity dimension (and pressure) is allowed to grow and collapse according to the mass conservation principle. An extensive experimental programme has been carried out in an experimental set-up composed of high-density polyethylene (HDPE) pipes, assembled at Instituto Superior T$\acute{e}$cnico of Lisbon, Portugal. The experimental facility is composed of a single pipeline with a total length of 203 m and inner diameter of 44 mm. The creep function of HDPE pipes was determined by using an inverse model based on transient pressure data collected during experimental runs without cavitating flow. Transient tests were carried out by the fast closure of the ball valves located at downstream end of the pipeline for the non-cavitating flow and at upstream for the cavitating flow. Once the rheological behaviour of HDPE pipes were known, computational simulations have been run in order to describe the hydraulic behaviour of the system for the cavitating pipe flow. The calibrated transient solver is capable of accurately describing the attenuation, dispersion and shape of observed transient pressures. The effects related to the viscoelasticity of HDPE pipes and to the occurrence of vapour pressures during the transient event are discussed.

A Case Study of Prediction and Analysis of Unplanned Dilution in an Underground Stoping Mine using Artificial Neural Network (인공신경망을 이용한 지하채광 확정선외 혼입 예측과 분석 사례연구)

  • Jang, Hyongdoo;Yang, Hyung-Sik
    • Tunnel and Underground Space
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    • v.24 no.4
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    • pp.282-288
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    • 2014
  • Stoping method has been acknowledged as one of the typical metalliferous underground mining methods. Notwithstanding with the popularity of the method, the majority of stoping mines are suffering from excessive unplanned dilution which often becomes as the main cause of mine closure. Thus a reliable unplanned dilution management system is imperatively needed. In this study, reliable unplanned dilution prediction system is introduced by adopting artificial neural network (ANN) based on data investigated from one underground stoping mine in Western Australia. In addition, contributions of input parameters were analysed by connection weight algorithm (CWA). To validate the reliability of the proposed ANN, correlation coefficient (R) was calculated in the training and test stage which shown relatively high correlation of 0.9641 in training and 0.7933 in test stage. As results of CWA application, BHL (Length of blast hole) and SFJ (Safety factor of Joint orientation) show comparatively high contribution of 18.78% and 19.77% which imply that these are somewhat critical influential parameter of unplanned dilution.

TIMBER AGE ESTIMATION OF COMMERCIAL TIMBERLAND IN TENNESSEE, USA USING REMOTELY SENSED DATA

  • Lee, Jung-Bin;Kim, Sung-Hoon;Jayakumar, S.;Heo, Joon
    • Proceedings of the KSRS Conference
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    • 2007.10a
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    • pp.449-451
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    • 2007
  • In the commercially managed timber lands, the information such as height, age, stand density, canopy closure and leaf area index need to be collected periodically. Stand volume is the most fundamental information in the valuation of timber, however, stand age information is the primary element of forest inventory and these two are highly correlated. Conventional method of collecting stand age information by field surveys such as ring count method is accurate; however, it is expensive, labor-intensive and time consuming. In the present study it was aimed to collect stand age information using modem techniques in a commercially managed timberland situated in Tennessee, USA. The Landsat Thematic Mapper (TM), Enhanced Thematic Mapper (ETM+) of three different periods, Shuttle Radar Topography Mission (SRTM), National elevation dataset (NED) and field inventory data were used. Normalized difference vegetation index (NDVI) and Tasselled Cap (TC) transformation techniques were applied on the TM and ETM+ data. The regression analysis was carried out to identify the correlation between stand age and NDVI, TC. In the present study about 2,469 datasets were analyzed. The $R^{2}$ value for stand age estimation was 0.713. The NDVI, TC2 and TC3 were found to produce accurate timber age information.

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EFFECT OF OVER-EXPANSION CYCLE IN A SPARK-IGNITION ENGINE USING LATE-CLOSING OF INTAKE VALVE AND ITS THERMODYNAMIC CONSIDERATION OF THE MECHANISM

  • Shiga, S.;Hirooka, Y.;Miyashita, Y.;Yagi, S.;Machacon, H.T.C.;Karasawa, T.;Nakamura, H.
    • International Journal of Automotive Technology
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    • v.2 no.1
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    • pp.1-7
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    • 2001
  • This paper presents further investigation into the effect of over-expansion cycle in a spark-ignition engine. On the basis of the results obtained in previous studies, several combinations of late-closing (LC) of intake valve and expansion ratio were tested using a single-cylinder production engine. A large volume of intake capacity was inserted into the intake manifold to simulate multi-cylinder engines. With the large capacity volume, LC can decrease the pumping loss and then increase the mechanical efficiency. Increasing the expansion ratio from 11 to 23.9 with LC application can produce about 13% improvement of thermal efficiency which was suggested to be caused by the increased cycle efficiency. The decrease of compression ratio from 11 to 5.5 gives little effect on the thermal efficiency if the expansion ratio could be kept constant. Thus, the expansion ratio is revealed to be a determining factor for cycle efficiency, while compression ratio is no more important, which suggests the usefulness of controlling the intake charge with intake valve closure timing. These were successfully explained by simple thermodynamic calculation and thus the mechanism could be verified by the estimation.

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Effect of the Advance Ratio on the Evolution of Propeller Wake (전진비가 추진기 후류에 미치는 영향)

  • Baek, Dong Geun;Yoon, Hyun Sik;Jung, Jae Hwan;Kim, Ki-Sup;Paik, Bu-Geun
    • Journal of the Society of Naval Architects of Korea
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    • v.51 no.1
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    • pp.1-7
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    • 2014
  • The present study numerically investigated the effect of the advance ratio on the wake characteristics of the marine propeller in the propeller open water test. Therefore, a wide range of the advance ratio(0.2${\kappa}-{\omega}$SST Model are considered. The three-dimensional vortical structures of tip vortices are visualized by the swirl strength, resulting in fast decay of the tip vortices with increasing the advance ratio. Furthermore, to better understanding of the wake evolution, the contraction ratio of the slip stream for different advance ratios is extracted from the velocity fields. Consequently, the slip stream contraction ratio decreases with increasing the advance ratio and successively the difference of the slip stream contraction ratio between J=0.2 and J=0.8 is about 0.1R.

Individual Tree Growth Models for Natural Mixed Forests in Changbai Mountains, Northeast China

  • Lu, Jun;Li, Fengri
    • Journal of Korean Society of Forest Science
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    • v.96 no.2
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    • pp.160-169
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    • 2007
  • The data used to develop distance-independent individual models for natural mixed forests were collected from 712 remeasured permanent sample plots (25,526 trees) of 10-year periodic from 1990 to 2000 in Baihe Forest Bureau of Changbai Mountains, northeast China. Based on analyzing relationship between diameter increment of individual trees with tree size, competitive status, and site condition, the diameter growth models for individual trees of 15 species growing in mixed-species uneven-aged forest stands, that have simple form, good predicting precision, and easily applicable, were developed using stepwise regression method. The main variables influencing on diameter increment of individual trees were tree size and competition, however, the site conditions were not significantly related with diameter increment. The tree size variables (lnDBH and $DBH^2$) were the most significant and important predictors of diameter growth existing in all 15 growth models. The diameter increment was directly proportional to tree diameter for each species. For the competitive factors in growth model, the relative diameter (RD), canopy closure (P), and the ratio of diameter of subject tree with maximum diameter (DDM) were contributed to the diameter increment at a certain extent. Other measures of stand density, such as basal area of stand (G) and stand density index (SDI), were not significantly influenced on diameter increment. Site factors, such as site index, slope and aspect were not important to diameter increment and excluded in the final models. The total variance explained by the final models of squared diameter increment ($R^2$) for all 15 species ranged from 35% to 72% and these results compared quit closely with those of Wykoff (1990) for mixed conifer stands. Using independent data set, validation measures were evaluated for predicting models of diameter increment developed in this study. The result indicated that the estimated precision was all greater than 94% and the models were suitable to describe diameter increment.

Evaluation of Non-Watertight Dural Reconstruction with Collagen Matrix Onlay Graft in Posterior Fossa Surgery

  • Kshettry, Varun R.;Lobo, Bjorn;Lim, Joshua;Sade, Burak;Oya, Soichi;Lee, Joung H.
    • Journal of Korean Neurosurgical Society
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    • v.59 no.1
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    • pp.52-57
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    • 2016
  • Objective : Many surgeons advocate for watertight dural reconstruction after posterior fossa surgery given the significant risk of cerebrospinal fluid (CSF) leak. Little evidence exists for posterior fossa dural reconstruction utilizing monolayer collagen matrix onlay graft in a non-watertight fashion. Our objective was to report the results of using collagen matrix in a non-watertight fashion for posterior fossa dural reconstruction. Methods : We conducted a retrospective review of operations performed by the senior author from 2004-2011 identified collagen matrix (DuraGen) use in 84 posterior fossa operations. Wound complications such as CSF leak, infection, pseudomeningocele, and aseptic meningitis were noted. Fisher's exact test was performed to assess risk factor association with specific complications. Results : Incisional CSF leak rate was 8.3% and non-incisional CSF leak rate was 3.6%. Incidence of aseptic meningitis was 7.1% and all cases resolved with steroids alone. Incidence of palpable and symptomatic pseudomeningocele in follow-up was 10.7% and 3.6% respectively. Postoperative infection rate was 4.8%. Previous surgery was associated with pseudomeningocele development (p<0.05). Conclusion : When primary dural closure after posterior fossa surgery is undesirable or not feasible, non-watertight dural reconstruction with collagen matrix resulted in incisional CSF leak in 8.3%. Incidence of pseudomeningocele, aseptic meningitis, and wound infection were within acceptable range. Data from this study may be used to compare alternative methods of dural reconstruction in posterior fossa surgery.