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Bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs : pilot study (성견의 열개형 골결손 부위에 골형성 유도술식을 동반한 임플란트 식립 후의 골형성 : pilot study)

  • Jeong, Ji-Yun;Sohn, Joo-Yeon;Chai, Kyung-Jun;Kim, Sung-Tae;Chung, Sung-Min;Lee, In-Seop;Cho, Kyoo-Sung;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.38 no.2
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    • pp.191-198
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    • 2008
  • Purpose: Guided bone regeneration(GBR) has emerged as a treatment in the management of osseous defects associated with dental implants. But several studies have reported different degrees of success of guided bone regeneration, depending upon the type of barrier selected, presence or absence of an underlying graft material, types of graft material, feasibility of technique, and clinician's preference. The aim of the present study was to evaluate bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs. Material and Methods: Standardized buccal dehiscence defects($3{\times}5\;mm$) were surgically 2 Mongrel dog's mandibles, each 8 SLA surface, 8 anodizing surface implants. Each buccal dehiscence defect received flap surgery only(no treatment, control), $Cytoflex^{(R)}$ membrane only, Resolut $XT^{(R)}$ membrane only, Resolut $XT^{(R)}+Osteon^{TM}$. Animals were sacrificed at 8 weeks postsurgery and block sections were harvested for histologic analysis. Resuts: All experimental group resulted in higher bone formation than control. Resolut $XT^{(R)}+Osteon^{TM}$ group resulted appeared highest defect resolution. There was no difference between SLA and anodizing surface, nonresorbable and resorbable membrane. Conclusion: GBR results in rapid and clinically relevant bone closure on dehiscence defects of the dental implants.

Injection Laryngoplasty for The Treatment of Vocal Fold Scar, and Sulcus (성대구증 및 성대 반흔 환자에서 주사후두성형술의 효과)

  • Woo, Joo Hyun;Baek, Min Kwan;Kim, Dong Young;Park, Hyoung-Min;An, Sanghee;Moon, Kwang Ha;Cha, Heung Eog
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.27 no.1
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    • pp.25-29
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    • 2016
  • Background and Objectives : The clinical reports for the treatment of vocal fold scar and sulcus vocalis are limited, also there is no best one for the treatment of them. This study is to evaluate the effect of Injection laryngoplasty (IL) for the treatment of vocal fold scar and sulcus vocalis. Materials and Methods : from January 2013 to May 2015, the Nineteen patients who were diagnosed as vocal fold scar, sulcus and atrophy, and underwent IL, were engaged in this study. Clinical information and voice parameters were analyzed by retrospective chart review. Pre and post voice parameters were compared. Results : Subgroups of diagnosis were classified into sulcus vocalis for 12 patients, vocal fold scar for 5, and atrophy for 2. IL was performed under local anesthesia through cricothyroid membrane except one patient. Atesense$^{(R)}$, Radiessess$^{(R)}$, and Rofilan$^{(R)}$ were used as injected materials in 9, 9, and 1 patients respectively. Maximal phonation time (p=0.0124), dynamic range (p=0.0028), pitch range (p=0.0141), voice handicap index (p=0.028), glottal closure (p=0.0229), and mucosal wave (p=0.0132) had significant improvement for post-IL voice assessment than Pre-IL. While GRBAS, Mean flow rate, Jitter, Shimmer, Harmony to Noise ratio didn't have improvement. Conclusion : IL is a feasible option for the treatment of glottis incompetence with normally mobile vocal folds such as sulcus vocalis and vocal fold scar.

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Processing of the Syntactic Ambiguity Resolution in English as a Foreign Language (외국어로서의 영어 구문 중의성 해결 과정)

  • 정유진;이윤형;황유미;남기춘
    • Proceedings of the Korean Society for Cognitive Science Conference
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    • 2000.05a
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    • pp.261-266
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    • 2000
  • 글을 이해하기 위해서는 어휘와 어휘간의 연결 및 전체 구조를 아는 것이 필요하다. 이는 비단 한국어뿐만 아니라 영어나 기타 다른 외국어에서도 마찬가지일 것이다. 본고는 두 가지를 고찰하기 위해 진행되었는데 우선 외국어로서 영어를 처리하는데 발생하는 구문적 중의성을 해결하는데 Garden Path Sentence(GPS), Late Closure(LC), PP의 세 문형에 따라 어떻게 해결하는지 알아보기 위한 것이다. 그리고 각 문형의 중의적 어절에서의 반응과 애매성 해소 어절에서의 반응에 따라 sysntactic module이 작용하는 것인지 알아보고자 한다. 예를 들어 "The boat floated down the streams sank"란 Garden Path 문장이 제시된 경우에 독자는 "sank"란 어휘가 제시되기 전까지 "floated"를 동사로 생각하게 되나 다음에 본동사인 "sank"가 제시될 경우 문장의 해석에 혼란을 갖게 될 것이다. 예문에서 "floated"가 문장에서 어떤 역할을 하는지 결정하는 것은 "sank"를 보고서야 가능하다. 이런 구문적 중의성을 해결하는 방식을 알아보기 위해 어절 단위로 제시된 자극을 읽는 자기 조절 읽기 과제(self-paced reading task)를 사용하였다. 각 어절을 읽는데 걸리는 시간을 측정한 실험 결과 GPS, PP, LC 모두 중의성을 지닌 영역이 중의성을 해소한 후와 각각 유형적으로 큰 차이가 없는 것으로 나타났다. 다만 GPS, CGPS, PP와 CPP는 어절 후반으로 갈수록 반응시간이 짧아졌다. 이는 우리나라 사람의 경우 외국어인 영어의 구문 중의성 해소는 구문 분석 단원(syntactic module)에 의한 자동적 처리라기보다 의미를 고려해 가면서 문법지식을 이용해 추론을 통한 구문 분석이라 할 수 있다.에 의한 자동적 처리라기보다 의미를 고려해 가면서 문법지식을 이용해 추론을 통한 구문 분석이라 할 수 있다.많았다(P<0.05).조군인 Group 1에서보다 높은 수준으로 발현되었다. 하지만 $12.5{\;}\mu\textrm{g}/ml$의 T. denticola sonicated 추출물로 전처리한 Group 3에서는 IL-2와 IL-4의 수준이 유의성있게 억제되어 발현되었다 (p < 0.05). 이러한 결과를 통하여 T. denticola에서 추출된 면역억제 단백질이 Th1과 Th2의 cytokine 분비 기능을 억제하는 것으로 확인 되었으며 이 기전이 감염 근관에서 발견되는 T. denticola의 치수 및 치근단 질환에 대한 병인기전과 관련이 있는 것으로 사료된다.을 보였다. 본 실험 결과, $Depulpin^{\circledR}은{\;}Tempcanal^{\circledR}와{\;}Vitapex^{\circledR}$에 비해 높은 세포 독성을 보여주공 있으나, 좀 더 많은 임상적 검증이 필요할 것으로 사료된다.중요한 역할을 하는 것으로 추론할 수 있다.근관벽을 처리하는 것이 필요하다고 사료된다.크기에 의존하며, 또한 이러한 영향은 $(Ti_{1-x}AI_{x})N$ 피막에 존재하는 AI의 함량이 높고, 초기에 증착된 막의 업자 크기가 작을 수록 클 것으로 여겨진다. 그리고 환경의 의미의 차이에 따라 경관의 미학적 평가가 달라진 것으로 나타났다.corner$적 의도에 의한 경관구성의 일면을 확인할수 있지만 엄밀히 생각하여 보면 이러한 예의 경우도 최락의 총체적인 외형은 마찬가지로 $\ulcorner$순응$\lrcorner$의 범위를 벗어나지 않는다. 그렇기 때문에도 $\ulcorner$순응$\lrcorner$$\ulcorner$표현$\lrcorner$의 성격과 형태를 외형상으로 더욱이 공간상에서는 뚜렷하게 경계

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Alveolar Cleft Reconstruction Using Chin Bone and Autogenous Tooth Bone Graft Material: Reports of 5 Cases

  • Jeong, Kyung-In;Lee, Junho;Kim, Kyung-Wook;Um, In-Woong;Hara, Shingo;Mitsugi, Masaharu;Kim, Young-Kyun
    • Journal of Korean Dental Science
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    • v.6 no.1
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    • pp.13-21
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    • 2013
  • Purpose: To report the successful results of using chin bone graft and autogenous tooth bone graft material (AutoBT) in alveolar cleft patients. Materials and Methods: Five patients with alveolar cleft defects underwent alveolar bone grafting. Three patients were treated using chin bone graft, and the other two patients underwent AutoBT graft. After implant site development using chin bone graft in the fi rst three cases, endosseous implant restorations were placed. In case #4 and 5, AutoBT graft material was placed to guide the normal eruption of partially impacted maxillary right canine and to the upper docking site after distraction osteogenesis. Result: Successful implant restorations with closure of the oronasal fistula were achieved in alveolar cleft defect reconstruction using either chin bone graft (Case #1, 2, 3) or AutoBT graft material (Case #4, 5). Case #4 showed enlarged follicle of the right maxillary canine, indicating a normal eruption guide pattern. Conclusion: Both chin bone graft and AutoBT graft showed favorable outcomes in reconstructing alveolar cleft defects. Autogenous tooth bone graft opens up the possibility of avoiding harvesting autogenous bone graft with complications and morbidities.

Changes of Cerebral Metabolism and the Related Factors during Cardiac Surgery

  • Park, Seok-Cheol
    • Biomedical Science Letters
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    • v.8 no.3
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    • pp.143-154
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    • 2002
  • The effect of cardiopulmonary bypass (CPB) on cerebral physiology during heart surgery remains incompletely understood. This study was carried out to investigate changes of cerebral metabolism and the association between the changes and clinical factors during heart surgery. Seventy adult patients (n=70) scheduled for elective cardiac surgery were participated in the present study. Middle cerebral artery blood flow velocity (V$_{MCA}$), cerebral arteriovenous oxygen content difference (C(a-v)O$_2$), cerebral oxygen extraction (COE), and modified cerebral metabolic rate for oxygen (MCMRO$_2$) were measured during six phases of the operation; Pre-CPB, CPB-10 min, Rewarm-1 (nasopharyngeal temperature 34$^{\circ}C$), Rewarm-2 (nasopharyngeal temperature 37$^{\circ}C$), CPB-off, and Post-OP (at skin closure after CPB-off). Each relationship of age, arterial blood gas parameters, or other variables to V$_{MCA}2$, C(a-v)O$_2$, COE, or MCMRO$_2$ was evaluated. V$_{MCA}$ increased (P<0.0001) whereas C(a-v)O$_2$ decreased (P<0.01) throughout the five phases of the operation compared to Pre-CPB value (control). COE diminished at CPB-10, Rewarm-1, and CPB-off (P<0.05) while MCMRO$_2$ reduced at CPB-10 and Rewarm-1 (P<0.05) compared to Pre-CPB value. Positive correlation was found between age and cerebral metabolic parameters (V$_{MCA}$, C(a-v)O$_2$, COE, or MCMRO$_2$) during CPB (range r=0.24 to 0.38, p<0.05). Four cerebral metabolic parameters had partially negative or positive correlation with arterial blood gas parameters and other variables (arterial blood pH, $O_2$ tension, $O_2$ content, $CO_2$ tension, blood pressure, blood flow, temperature, or hematocrit) during the operation. In conclusion, CPB led to marked alterations of cerebral metabolism and age, pH, and $CO_2$ tension profoundly influenced the changes during cardiac surgery.

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Drag reduction for payload fairing of satellite launch vehicle with aerospike in transonic and low supersonic speeds

  • Mehta, R.C.
    • Advances in aircraft and spacecraft science
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    • v.7 no.4
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    • pp.371-385
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    • 2020
  • A forward-facing aerospike attached to a payload fairing of a satellite launch vehicle significantly alters its flowfield and decreases the aerodynamic drag in transonic and low supersonic speeds. The present payload fairing is an axisymmetric configuration and consists of a blunt-nosed body along with a conical section, payload shroud, boat tail and followed by a booster. The main purpose of the present numerical simulations is to evaluate flowfield and assess the performance of aerodynamic drag coefficient with and without aerospike attached to a payload fairing of a typical satellite launch vehicle in freestream Mach number range 0.8 ≤ M ≤ 3.0 and freestream Reynolds number range 33.35 × 106/m ≤ Re ≤ 46.75 × 106/m whichincludes the maximum aerodynamic drag and maximum dynamic conditions during ascent flight trajectory of the satellite launch vehicle. A numerical simulation has been carried out to solve time-dependent compressible turbulent axisymmetric Reynolds-averaged Navier-Stokes equations. The closure of the system of equations is achieved using the Baldwin-Lomax turbulence model. The aerodynamic drag reduction mechanism is analysed employing numerical results such as velocity vector plots, density and Mach contours in conjunction with the experimental flow visualization pictures. The variations of wall pressure coefficient over the payload fairing with and without aerospike are exhibiting different kind of flowfield characteristics in the transonic and low supersonic speeds. The numerically computed results are compared with schlieren pictures, oil flow patterns and measured wall pressure distributions and exhibit good agreement between them.

REPAIR OF BILATERAL CLEFT LIP AND NOSE: PRINCIPLES AND METHODS OF MULLIKEN (양측 구순열비의 교정술: Mulliken의 원칙과 방법)

  • Jung, Young-Soo;Mulliken, John B.;Sullivan, Stephen R.;Padwa, Bonnie L.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.4
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    • pp.353-360
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    • 2009
  • The principles for repair of bilateral cleft lip and nasal deformity are 1) symmetry, 2) primary muscular continuity, 3) proper philtral size and shape, 4) formation of the median tubercle and vermilion-cutaneous ridge from lateral labial elements, and 5) primary positioning of the alar cartilages to construct the nasal tip and columella. The authors underscore the essential role of preoperative premaxillary positioning for the synchronous closure of the cleft lip and primary palate, and describe Mulliken's operative technique. We discuss three-dimensional adjustments based on predicted fourth-dimensional changes. In a consecutive series of 50 patients, no revisions were necessary for philtral size or columellar length. Preoperative premaxillary positioning and primary repair of bilateral cleft lip and nasal deformity may impair maxillary growth. Nevertheless, a symmetric nasolabial appearance, rather than emphasis on maxillary growth, is the priority for the child with bilateral cleft lip.

Study on Heterogeneous Structures and High-Frequency Magnetic Properties Amorphous CoZrNb Thin Films (비정질 CoZrNb 박막의 불균일 구조와 고주파 자기특성에 관한 연구)

  • 정인섭;허재헌
    • Journal of the Korean Magnetics Society
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    • v.1 no.2
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    • pp.31-36
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    • 1991
  • Structural and compositional heterogeneities of sputter deposited, amorphous $Co_{87}Zr_{4}NB_{9}$ thin films were investigated using TEM and EDS with windowless detector. The films deposited with substrate bias and annealed in rotating magnetc field showed two amorphous phases of Co-rich region and (ZrNb)oxide-rich region, and revealed 'ultra-soft' magnetic properties. Revesible bias-responses and overdamped frequency responses, along with small Hc, Hk and Mr/Ms ratio, give the possibility of ultra-soft magnetic behavior fo CoZrNb thin films. We proposed the vortex type magnetization distribution in remanent state which was correlated with the thin film heterogeneity. Then, the ultra-soft characteristics of the compositionally heterogeneous films were explained by the spin vortices that minimized the total magnetostatic and exchange coupling energies.

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Full mouth prosthodontic reconstruction on patient with occlusion collapse & decreased vertical dimension (교합 붕괴 환자의 수직고경거상을 동반한 완전 구강회복 증례)

  • Yoo, H.J.;Choi, M.H.;Kim, C.H.;Park, Y.R.;Kang, D.W.
    • Journal of Dental Rehabilitation and Applied Science
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    • v.19 no.2
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    • pp.115-124
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    • 2003
  • One of the important things in the full mouth reconstruction is the determination of therapeutic position. Centric jaw relation is used as a therapeutic position for the full mouth reconstruction. There are several techniques associated with recording this position. Five clinically acceptable techniques are as follows: 1) Swallowing or free closure, 2) Chin point guidance, 3) Bimanual method 4) Myo-monitor technique, 5) Anterior deprogrammer. Centric relation obtained utilizing the anterior acrylic resin platform in this case. Another important thing in full mouth reconstruction is provisional restoration. Provisional restorations are an excellent diagnostic instrument, especially in full remain esthetics, phonetics, function, parafunction, and dysfunction after evaluation and acceptance through clinical trial with the provisional restorations should be accurately transferred to the final restorations to ensure the same clinical success. Especially, anterior guidance should be accurately transferred to the final restorations. An accurate anterior guidance is critical for optimal esthetics, phonetics, comfort, function, stress minimization, and longevity of teeth and restorations. To record optimum anterior guidance, customized anterior guide table is used in this case. Considering previously mentioned points, we did successive treatment. And it resulted in a better situation esthetically and functionally. Followings are what we cared in treating a patient in this case. 1) Accurate centric relation recording 2) Accurate transference of anterior guidance to the final restorations.

Voltammetric Studies on Some Thiadiazoles and Their Derivatives

  • Maghraby, A. A. El;Abou-Elenien, G. M.;Rateb, N. M;Abdel-Tawab, H. R.
    • Journal of the Korean Electrochemical Society
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    • v.12 no.1
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    • pp.54-60
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    • 2009
  • The redox characteristics of 2-arylaldehydehydrazono-3-phenyl-5-substituted-2, 3-dihydro-1, 3, 4-thiadiazoles (1a-h) have been investigated in nonaqueous solvents such as 1, 2-dichloroethane (DCE), dichloromethane (DCM), acetonitrile (AN), Tetrahydrofuran (THF), and dimethylsulfoxide (DMSO) at platinum electrode. Through controlled potential electrolysis, the oxidation and reduction products of the investigated compounds had been separated and indentified. The redox mechanism had been suggested and proved. It had been found that all the investigated compounds were oxidized in two irreversible one-electron processes following the well-known pattern of The EC-mechanism; the first electron loss gives the corresponding cation-radical which is followed by proton removal from the ortho-position in the N-phenyl ring forming the radical. The obtained radical undergoes a second electron uptake from the nitrogen in the N = C group forming the unstable intermediate (di-radical cation) which undergoes ring closure forming the corresponding cation. The formed cation was stabilized in solution through its combination with a perchlorate anion from the medium. On the other hand, these compounds are reduced in a single two-electron process or in a successive two one-electron processes following the well known pattern of the EEC-mechanism according to the nature of the substituent; the first one gives the anion-radical followed by a second electron reduction to give the dianion which is basic enough to abstract protons from the media to saturate the (C = O) bond.