• Journal of Biomedical Engineering Research
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• v.21 no.3 s.61
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• pp.303-309
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• 2000

An accurate quantitative biomechanical evaluation for the spasticity caused by the disorder of central nervous system was made in this study. A sudden leg dropper was designed to generate objective testing environment at every trial. 3-dimensional motion analysis system(Elite. B.T.S. Italy) was used to measure kinematic data which were angle. and angular velocity of a lower limb. A program was developed to analyze the kinematic data of lower limb motion. and dynamic EMG data at the same time. To evaluate spasticity quantitatively. total 26 parameters including 14 parameters newly driven were analyzed, and statistical analysis were made for bilateral correlations. Results showed possibility to make accurate quantitative and objective evaluation for spasticity with various new parameters using new devices and program.

• Natural Product Sciences
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• v.22 no.2
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• pp.93-101
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• 2016

For efficient quality control of the Samryeongbaekchul-san decoction, a powerful and accurate an ultra-performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry (MS) method was developed for quantitative analysis of the thirteen constituents: allantoin (1), spinosin (2), liquiritin (3), ginsenoside Rg1 (4), liquiritigenin (5), platycodin D2 (6), platycodin D (7), ginsenoside Rb1 (8), glycyrrhizin (9), 6-gingerol (10), atractylenolide III (11), atractylenolide II (12), and atractylenolide I (13). Separation of the compounds 1 - 13 was performed on a UPLC BEH $C_{18}$ column ($2.1{\times}100mm$, $1.7{\mu}m$) at a column temperature of $40^{\circ}C$ with a gradient solvent system of 0.1% (v/v) formic acid aqueous-acetonitrile. The flow rate and injection volume were 0.3 mL/min and $2.0{\mu}L$. Calibration curves of all compounds were showed good linearity with values of the correlation coefficient ${\geq}0.9920$ within the test ranges. The values of limits of detection and quantification for all analytes were 0.04 - 4.53 ng/mL and 0.13 - 13.60 ng/mL. The result of an experiment, compounds 2, 6, 12, and 13 were not detected while compounds 1, 3 - 5, and 7 - 11 were detected with 1,570.42, 5,239.85, 299.35, 318.88, 562.27, 340.87, 12,253.69, 73.80, and $115.01{\mu}g/g$, respectively.

• Journal of dental hygiene science
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• v.21 no.4
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• pp.219-226
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• 2021

Background: Proper detection and management of dental plaque are essential for individual oral health. We aimed to evaluate the maturation level of dental plaque using a two-tone disclosing agent and to compare it with the fluorescence of dental plaque on the quantitative light-induced fluorescence (QLF) image to obtain primary data for the development of a new dental plaque scoring system. Methods: Twenty-eight subjects who consented to participate after understanding the purpose of the study were screened. The images of the anterior teeth were obtained using the QLF device. Subsequently, dental plaque was stained with a two-tone disclosing solution and a photograph was obtained with a digital single-lens reflex (DSLR) camera. The staining scores were assigned as follows: 0 for no staining, 1 for pink staining, and 2 for blue staining. The marked points on the DSLR images were selected for RGB color analysis. The relationship between dental plaque maturation and the red/green (R/G) ratio was evaluated using Spearman's rank correlation. Additionally, different red fluorescence values according to dental plaque accumulation were assessed using one-way analysis of variance followed by Scheffe's post-hoc test to identify statistically significant differences between the groups. Results: A comparison of the intensity of red fluorescence according to the maturation of the two-tone stained dental plaque confirmed that R/G ratio was higher in the QLF images with dental plaque maturation (p<0.001). Correlation analysis between the stained dental plaque and the red fluorescence intensity in the QLF image confirmed an excellent positive correlation (p<0.001). Conclusion: A new plaque scoring system can be developed based on the results of the present study. In addition, these study results may also help in dental plaque management in the clinical setting.

• BioChip Journal
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• v.16
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• pp.82-98
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• 2020

We report a quantitative and systematic method for determining 3D-printing and surface-treatment conditions that can help improve the optical quality of direct-printed microfluidic devices. Digital light processing (DLP)-stereolithography (SLA) printing was extensively studied in microfluidics owing to the rapid, one-step, cleanroom-free, maskless, and high-definition microfabrication of 3D-microfluidic devices. However, optical imaging or detection for bioassays in DLP-SLA-printed microfluidic devices are limited by the translucence of photopolymerized resins. Various approaches, including mechanical abrasions, chemical etching, polymer coatings, and printing on transparent glass/plastic slides, were proposed to address this limitation. However, the effects of these methods have not been analyzed quantitatively or systematically. For the first time, we propose quantitative and methodological determination of 3D-printing and surface-treatment conditions, based on optical-resolution analysis using USAF 1951 resolution test targets and a fluorescence microbead slide through 3D-printed coverslip chips. The key printing parameters (resin type, build orientation, layer thickness, and layer offset) and surface-treatment parameters (grit number for sanding, polishing time with alumina slurry, and type of refractive-index-matching coatings) were determined in a step-wise manner. As a result, we achieved marked improvements in resolution (from 80.6 to 645.1 lp/mm) and contrast (from 3.30 to 27.63% for 645.1 lp/mm resolution). Furthermore, images of the fluorescence microbeads were qualitatively analyzed to evaluate the proposed 3D-printing and surface-treatment approach for fluorescence imaging applications. Finally, the proposed method was validated by fabricating an acoustic micromixer chip and fluorescently visualizing cavitation microstreaming that emanated from an oscillating bubble captured inside the chip. We expect that our approach for enhancing optical quality will be widely used in the rapid manufacturing of 3D-microfluidic chips for optical assays.

• YAKHAK HOEJI
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• v.58 no.4
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• pp.250-254
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• 2014

Background: A new admission procedure was introduced to Korea when Doctor of Pharmacy (Pharm. D.) program was first established in 2011. In the new procedure, applicants are reviewed based on quantitative qualifications, which include Pharmacy Education Eligibility Test (PEET) scores, Test of English for International Communication (TOEIC) scores, and grade point average (GPA), as well as qualitative qualifications such as essay writing, extracurricular activities including volunteer experiences. Purpose: This study aimed to find relationships between entrance qualifications and academic performance of pharmacy students. Method: Entrance qualifications and academic performance of 164 first-year students were analyzed from 2011 to 2013 at Catholic University of Daegu. Other characteristics such as age and gender were also considered in the study. Results: Only GPA and TOEIC scores showed positive Pearson correlation with academic performance, while PEET scores did not. Conclusion: GPA and TOEIC scores could potentially have predictive validity for academic performance in pharmacy school. PEET scores, however, should simply be considered as pre-entrance qualifications, without predictive validity for academic performance.

• Bulletin of the Korean Chemical Society
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• v.32 no.11
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• pp.3865-3872
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• 2011

A quantitative structure-property relationship (QSPR) study was performed for the prediction of the absorption maxima of azobenzene dyes. The entire set of 191 azobenzenes was divided into a training set of 150 azobenzenes and a test set of 41 azobenzenes according to Kennard and Stones algorithm. A seven-descriptor model, with squared correlation coefficient ($R^2$) of 0.8755 and standard error of estimation (s) of 14.476, was developed by applying stepwise multiple linear regression (MLR) analysis on the training set. The reliability of the proposed model was further illustrated using various evaluation techniques: leave-many-out crossvalidation procedure, randomization tests, and validation through the test set.

• Journal of Information Technology Services
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• v.18 no.5
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• pp.193-207
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• 2019

In recent years, Digital Social Innovation has been emerging at home and abroad and new solutions are being proposed by the perspective of User using digital technology in order to solve social and economic problems of the city. In addition, Living Labs which is an innovative tools and space enable to solve problems doing activities with various participants led by users. Therefore, this study aims to systematically manage the activities of Living Lab in Digital Social Innovation and improves the Living Lab sustainability using the performance indicators which are going to be developed. Furthermore, construct the appropriate indicator of each project process and take test at real Living Labs. As a result, performance indicator was derived from each procedure in the Living Lab project, and proved validity and reliability of the indicators through qualitative and quantitative methods by interviews and the questionnaire from the participants of Living Labs.

• Transactions of the Korean Society of Mechanical Engineers
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• v.8 no.1
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• pp.41-47
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• 1984

Increase of the requirements on quality of welded structures necessitates the improvement of known inspection methods and the introduction of progressive new techniques. Non-destructive methods are the most advanced, but there are considerable difficulties in using the methods of radiography with electromagnetic rays and ultrasonic testing in the inspection of dissimilar metal friction welds, because their physical and mechanical properties are changed very rapidly at the interface. The values of simple mechanical test for dissimilar metal friction welds have always been dubious, as the strength of the bond is often greater than that of the softer materials being jointed. Thus, in this paper some conventional mechanical testing methods are examined in an attempt to determine a technique for dissimilar metal friction welds, which will give a reliable quantitative indication of the weld quality. From the considered static and dynamic testing methods the impact bending test on unnotched and notched specimens are the most sensitive to find out the small joining defects in the interface.

• Journal of the Korean Institute of Landscape Architecture
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• v.15 no.2
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• pp.91-100
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• 1987

Main purpose of this study is to test the usefulness of the SBE method in measuring ‘complexity’‘beauty’and ‘friendliness’other than ‘preference’. The study results are as follows. 1) The SBE results are as reliable and valid in measuring ‘complexity’‘beauty’and ‘friendliness’as in measuring ‘preference’. However, the degree of reliability and convergent validity can vary according to the inherent charateristics of those abstract quality themselves. 2) The correlation coefficients among the result of rating, SBE, frequency, and paired comparison methods are very high. 3) The perceived beauty of urban residential landscape reaches highest at the higher complexity level than that of the rural residential landscape.

• International Journal of Automotive Technology
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• v.3 no.4
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• pp.157-163
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• 2002

It is well recognized that the ultrasonic method is one of the most common and reliable nondestructive testing (NDT) methods for the quantitative estimation of defects in welded structures. However, NDT techniques applying for adhesively bonded joints have not been clearly established yet. In this paper, the detection of interface crack by the ultrasonic method was applied for the measurement of interfacial crack length in the adhesively bonded joints of double-cantilever beam (DCB). An optimal condition of transmission coefficients and experimental accuracy by the ultrasonic method in the adhesively bonded joints have been investigated and discussed. The experimental values are in good agreement with the computed results by boundary element method (BEM) and Ripling's equation.