• Title/Summary/Keyword: quantitative models

Search Result 1,006, Processing Time 0.023 seconds

An Approach to Generation Monitoring Module using UML Model (UML모델을 이용한 모니터링 모듈 생성 방법)

  • Park, Jeong-Min;Jeong, Ok-Ran
    • Journal of the Korea Society of Computer and Information
    • /
    • v.16 no.9
    • /
    • pp.57-68
    • /
    • 2011
  • Self-healing is an approach to evaluating constraints defined in target system and to applying an appropriate strategy when violating the constrains. Today, the computing environment is very complex, so researches that endow a system with the self-healing's ability that recognizes problem arising in a target system are being an important issues. However, most of the existing researches are that self-healing developers need much effort and time to analyze and model constraints. Thus, in order to improve these problems, this paper proposes the method that automatically generates monitoring module by using UML models for self-healing. The approach proposes: 1) defining system knowledge required for self-healing from UML model, 2) process for generating monitor, by using monitor generated, and process for monitoring the problems. Through these, we can reduce the efforts of self-healing developers to analyze target system, and secure monitoring scope based on information of system knowledge. Also we can minimize the efforts to develop the monitoring environment automatically. to evaluate the proposed approach, we apply proposed approach to ATM prototype system for qualitative result, and perform quantitative evaluation through video conference system in our existing research.

3D-QSAR Analyses on the Inhibition Activity of 4-($R_1$)-Benzyl Alcohol and 4-($R_2$)-Phenol Analogues Against Tyrosinase (4-($R_1$)-Benzyl alcohol 및 4-($R_2$)-Phenol 유도체들의 Tyrosinase 활성 저해에 대한 3D-QSAR 분석)

  • Kim, Sang-Jin;Lee, Myoung-Hee
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.35 no.4
    • /
    • pp.271-276
    • /
    • 2009
  • The 3-dimensional quantitative structure-activity relationships (3D-QSARs) models between the substituents with changing groups ($R_1$ & $R_2$) of 4-($R_1$)-benzyl alcohol and 4-($R_2$)-phenol derivatives as substrate molecule and their inhibitory activities against tyrosinase were derived and discussed quantitatively. The optimized CoMSIA 2 model have best predictability and fitness ($r^2\;=\;0.858$ & $q^2\;=\;0.951$). The contour maps of optimized CoMSIA 2 model showed that, the inhibitory activities of the analogues against tyrosinase were expected to increase when hydrophobic favor, negative charge favor, steric disfavor and hydrogen bond donor disfavor groups were substituted at the $R^2$ position. When the positive charge and the hydrogen bond donor favor groups were substituted at the $R_1$ position, it is predicted that the substituents will be able to increase the inhibitory activity. However, hydrogen bond acceptor did not affect inhibitory activities of tyrosinase.

A Study on Statistical Parameters for the Evaluation of Regional Air Quality Modeling Results - Focused on Fine Dust Modeling - (지역규모 대기질 모델 결과 평가를 위한 통계 검증지표 활용 - 미세먼지 모델링을 중심으로 -)

  • Kim, Cheol-Hee;Lee, Sang-Hyun;Jang, Min;Chun, Sungnam;Kang, Suji;Ko, Kwang-Kun;Lee, Jong-Jae;Lee, Hyo-Jung
    • Journal of Environmental Impact Assessment
    • /
    • v.29 no.4
    • /
    • pp.272-285
    • /
    • 2020
  • We investigated statistical evaluation parameters for 3D meteorological and air quality models and selected several quantitative indicator references, and summarized the reference values of the statistical parameters for domestic air quality modeling researcher. The finally selected 9 statistical parameters are MB (Mean Bias), ME (Mean Error), MNB (Mean Normalized Bias Error), MNE (Mean Absolute Gross Error), RMSE (Root Mean Square Error), IOA (Index of Agreement), R (Correlation Coefficient), FE (Fractional Error), FB (Fractional Bias), and the associated reference values are summarized. The results showed that MB and ME have been widely used in evaluating the meteorological model output, and NMB and NME are most frequently used for air quality model results. In addition, discussed are the presentation diagrams such as Soccer Plot, Taylor diagram, and Q-Q (Quantile-Quantile) diagram. The current results from our study is expected to be effectively used as the statistical evaluation parameters suitable for situation in Korea considering various characteristics such as including the mountainous surface areas.

Some Determinants of manager Style and household Work Organization on the Urban Homemakers in Korea (도시주부의 가사노동 조직화 및 관리자 유형 분석)

  • 채옥희
    • Journal of Families and Better Life
    • /
    • v.6 no.1
    • /
    • pp.189-203
    • /
    • 1988
  • The main objective of this dissertation is to find out the measurement methods of household work organization and manger style and the quantitative analysis methods of influential factors on household work organization and manager style. Subjects were homemakers living in metropolitan , medium and small cities. Questionnaires were sent to subjects and usable responses were 1139 out of 1239 received questionnaires. Data collected through both preliminary and main survey were analyzed by using frequencies, percentage, analysis of variance, chi-square test and pearson's correlation analysis. Results are as follows; 1) The degree of household work organization was distributed on upper middle level exceeding middle score. Among subsystems of household work such as task assignment , test regularization, task arrangement and task standardization. subjects show the highest positive attitude in task standardization. 2) The characteristics of management in household work have task centered orientation. By the prority of task centered orientation, the order was integrated style. dedicated style. It means that the most ideal style is an integrated style which accounts for one-third of the total homemakers. 3) Household organization's subsystems and household work manager style are related with socio-demographic variables. Integrated style is significantly related with homemaker's employment and having helpers for household work. homemakers who are employed and have helpers for household work exhibit high scores in task assignment and task arrangement. Dedicated style is significantly related with homemaker's age and the number of children. Homemakers who are older and have many children exhibit high scores in task assignment. Related style is significantly related with marriage duration, education level and income level. Homemakers who have a long marriage duration exhibit high scores in task assignment and who have high education and income level exhibit high scores in task regularization. Seperates style is significantly related with homemaker's age m marriage duration an family life cycle. homemakers who ar older, have a long marriage duration and are of late stage in family life cycle exhibit seperated style and high scores in organization. To summarize research findings, household work manger and household work organization are related with family life experiences, and task assignment is an influential variable on manager style. in conclusion, it is evident that household work organization emphasizes efficiency as cognitive component and such organization. Finally it is necessary to broaden this research considered social psychological variables. And also it needs to build household manger style models appropriate fro the characteristics of each style.

  • PDF

Vegetable Oil Intake and Breast Cancer Risk: a Meta-analysis

  • Xin, Yue;Li, Xiao-Yu;Sun, Shi-Ran;Wang, Li-Xia;Huang, Tao
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.12
    • /
    • pp.5125-5135
    • /
    • 2015
  • Background: Total fat intake may be associated with increased risk of breast cancer, and fish oil has been suggested as a protection factor to breast cancer. But the effect of vegetable oils is inconclusive. We aimed to investigate the association with high vegetable oils consumption and breast cancer risk, and evaluated their dose-response relationship. Design: We systematically searched the MEDLINE, EMBASE, Cochrane databases, and CNKI updated to December 2014, and identified all observational studies providing quantitative estimates between breast cancer risk and different vegetable oils consumption. Fixed or random effect models were used to estimate summary odds ratios for the highest vs. lowest intake, and dose-response relationship was assessed by restricted cubic spline model and generalized least-squares trend (GLST) model. Results: Five prospective cohort studies and 11 retrospective case-control studies, involving 11,161 breast cancer events from more than 150,000 females, met the inclusion criteria. Compared with the lowest vegetable oils consumption, higher intake didn't increased the risk of breast cancer with pooled OR of 0.88 (95% CIs:0.77-1.01), and the result from dose-response analyses didn't show a significant positive or negative trend on the breast cancer risk for each 10g vegetable oil/day increment (OR=0.98, 95% CIs: 0.95-1.01). In the subgroup analyses, the oils might impact on females with different strata of BMI. Higher olive oil intake showed a protective effect against breast cancer with OR of 0.74 (95% CIs: 0.60-0.92), which was not significant among the three cohort studies. Conclusions: This meta-analyses suggested that higher intake of vegetable oils is not associated with the higher risk of breast cancer. Olive oil might be a protective factor for the cancer occurrence among case-control studies and from the whole. Recall bias and imbalance in study location and vegetable oils subtypes shouldn't be ignored. More prospective cohort studies are required to confirm the interaction of the impact of vegetable oils on different population and various cancer characteristic, and further investigate the relationship between different subtype oils and breast cancer.

The Fuzzy QFD Approach to Importance the Public Sector Information Performance Measurement Category (퍼지 QFD를 활용한 공공부문 정보화 성과 측정범주 중요도 도출)

  • Oh, Jin-Seok;Song, Young-Il
    • Information Systems Review
    • /
    • v.12 no.2
    • /
    • pp.189-203
    • /
    • 2010
  • Is presenting guidance of information performance measurement as government PRM version 2.0 these common reference models in public sector. Government PRM is consisted of assessment classification system and standard line of sight and performance management standard form. Through this, is sorting performance element and define cause-and effect. Government PRM is supplying measurement categories at assessment classification system, but relative importance for application standard by measurement categories is not presenting. In this study, importance for government PRM's measurement categories been applying by commonness Test of information performance measurement of public sector wishes to deduce estimation and priority. Research model used Fuzzy QFD, and designed so that can reflect well PRM's development purpose. I applied Fuzzy AHP and FPP method that graft together fuzzy theory to minimize uncertainty and ambiguity in that expert opinion. Is drawn to element that "Standard model offer for information department and management" is the most important in government PRM's development purpose. "Quality of service" is showing the highest priority in customer results in measurement category. Importance for government PRM's measurement categories can offer common valuation basis in government and public institution. Hereafter if examine closely quantitative cause-and effect for structure model of measurement classification system when study government PRM more objective and efficient reference model become.

Genome-wide association study reveals genetic loci and candidate genes for average daily gain in Duroc pigs

  • Quan, Jianping;Ding, Rongrong;Wang, Xingwang;Yang, Ming;Yang, Yang;Zheng, Enqin;Gu, Ting;Cai, Gengyuan;Wu, Zhenfang;Liu, Dewu;Yang, Jie
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.31 no.4
    • /
    • pp.480-488
    • /
    • 2018
  • Objective: Average daily gain (ADG) is an important target trait of pig breeding programs. We aimed to identify single nucleotide polymorphisms (SNPs) and genomic regions that are associated with ADG in the Duroc pig population. Methods: We performed a genome-wide association study involving 390 Duroc boars and by using the PorcineSNP60K Beadchip and two linear models. Results: After quality control, we detected 3,5971 SNPs, which included seven SNPs that are significantly associated with the ADG of pigs. We identified six quantitative trait loci (QTL) regions for ADG. These QTLs included four previously reported QTLs on Sus scrofa chromosome (SSC) 1, SSC5, SSC9, and SSC13, as well as two novel QTLs on SSC6 and SSC16. In addition, we selected six candidate genes (general transcription factor 3C polypeptide 5, high mobility group AT-hook 2, nicotinamide phosphoribosyltransferase, oligodendrocyte transcription factor 1, pleckstrin homology and RhoGEF domain containing G4B, and ENSSSCG00000031548) associated with ADG on the basis of their physiological roles and positional information. These candidate genes are involved in skeletal muscle cell differentiation, diet-induced obesity, and nervous system development. Conclusion: This study contributes to the identification of the casual mutation that underlies QTLs associated with ADG and to future pig breeding programs based on marker-assisted selection. Further studies are needed to elucidate the role of the identified candidate genes in the physiological processes involved in ADG regulation.

Evaluation of Cardiac Function Analysis System Using Magnetic Resonance Images

  • Tae, Ki-Sik;Suh, Tae-Suk;Choe, Bo-Young;Lee, Hyoung-Koo;Shinn, Kyung-Sub;Jung, Seung-Eun;Lee, Jae-Moon
    • Progress in Medical Physics
    • /
    • v.10 no.3
    • /
    • pp.159-168
    • /
    • 1999
  • Cardiac disease is one of the leading causes of death in Korea. In quantitative analysis of cardiac function and morphological information by three-dimensional reconstruction of magnetic resonance images, left ventricle provides an important role functionally and physiologically. However, existing procedures mostly rely on the extensive human interaction and are seldom evaluated on clinical applications. In this study, we developed a system which could perform automatic extraction of enpicardial and endocardial contour and analysis of cardiac function to evaluate reliability and stability of each system comparing with the result of ARGUS system offered 1.5T Siemens MRI system and manual method performed by clinicians. For various aspects, we investigated reliability of each system by compared with left ventricular contour, end-diastolic volume (EDV), end-systolic volume (ESV), stock volume (SV), ejection fraction (EF), cardiac output (CO) and wall thickness (WT). When comparing with manual method, extracted results of developed process using minimum error threshold (MET) method that automatically extracts contour from cardiac MR images and ARGUS system were demonstrated as successful rate 90% of the contour extraction. When calculating cardiac function parameters using MET and comparing with using correlation coefficients analysis method, the process extracts endocardial and epicardial contour using MET, values from automatic and ARGUS method agreed with manual values within :t 3% average error. It was successfully demonstrated that automatic method using threshold technique could provide high potential for assessing of each parameters with relatively high reliability compared with manual method. In this study, the method developed in this study could reduce processing time compared with ARGUS and manual method due to a simple threshold technique. This method is useful for diagnosis of cardiac disease, simulating physiological function and amount of blood flow of left ventricle. In addition, this method could be valuable in developing automatic systems in order to apply to other deformable image models.

  • PDF

Assessing the Impact of Climate Change on Water Resources: Waimea Plains, New Zealand Case Example

  • Zemansky, Gil;Hong, Yoon-Seeok Timothy;Rose, Jennifer;Song, Sung-Ho;Thomas, Joseph
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2011.05a
    • /
    • pp.18-18
    • /
    • 2011
  • Climate change is impacting and will increasingly impact both the quantity and quality of the world's water resources in a variety of ways. In some areas warming climate results in increased rainfall, surface runoff, and groundwater recharge while in others there may be declines in all of these. Water quality is described by a number of variables. Some are directly impacted by climate change. Temperature is an obvious example. Notably, increased atmospheric concentrations of $CO_2$ triggering climate change increase the $CO_2$ dissolving into water. This has manifold consequences including decreased pH and increased alkalinity, with resultant increases in dissolved concentrations of the minerals in geologic materials contacted by such water. Climate change is also expected to increase the number and intensity of extreme climate events, with related hydrologic changes. A simple framework has been developed in New Zealand for assessing and predicting climate change impacts on water resources. Assessment is largely based on trend analysis of historic data using the non-parametric Mann-Kendall method. Trend analysis requires long-term, regular monitoring data for both climate and hydrologic variables. Data quality is of primary importance and data gaps must be avoided. Quantitative prediction of climate change impacts on the quantity of water resources can be accomplished by computer modelling. This requires the serial coupling of various models. For example, regional downscaling of results from a world-wide general circulation model (GCM) can be used to forecast temperatures and precipitation for various emissions scenarios in specific catchments. Mechanistic or artificial intelligence modelling can then be used with these inputs to simulate climate change impacts over time, such as changes in streamflow, groundwater-surface water interactions, and changes in groundwater levels. The Waimea Plains catchment in New Zealand was selected for a test application of these assessment and prediction methods. This catchment is predicted to undergo relatively minor impacts due to climate change. All available climate and hydrologic databases were obtained and analyzed. These included climate (temperature, precipitation, solar radiation and sunshine hours, evapotranspiration, humidity, and cloud cover) and hydrologic (streamflow and quality and groundwater levels and quality) records. Results varied but there were indications of atmospheric temperature increasing, rainfall decreasing, streamflow decreasing, and groundwater level decreasing trends. Artificial intelligence modelling was applied to predict water usage, rainfall recharge of groundwater, and upstream flow for two regionally downscaled climate change scenarios (A1B and A2). The AI methods used were multi-layer perceptron (MLP) with extended Kalman filtering (EKF), genetic programming (GP), and a dynamic neuro-fuzzy local modelling system (DNFLMS), respectively. These were then used as inputs to a mechanistic groundwater flow-surface water interaction model (MODFLOW). A DNFLMS was also used to simulate downstream flow and groundwater levels for comparison with MODFLOW outputs. MODFLOW and DNFLMS outputs were consistent. They indicated declines in streamflow on the order of 21 to 23% for MODFLOW and DNFLMS (A1B scenario), respectively, and 27% in both cases for the A2 scenario under severe drought conditions by 2058-2059, with little if any change in groundwater levels.

  • PDF

Analytical Study of Ultimate Behavior of Steel Cable-stayed Bridges (완성계 강사장교의 극한 거동의 해석적 연구)

  • Kim, Seungjun;Im, Seok-Been;Lee, Kee-Sei;Kang, Young-Jong
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.32 no.2A
    • /
    • pp.85-95
    • /
    • 2012
  • This paper presents an investigation on the ultimate behavior of steel cable-stayed bridges using nonlinear finite element analysis method. Cable-stayed bridges exhibit various geometric nonlinearities as well as material nonlinearities, so rational nonlinear finite element analysis should be performed for investigation of the ultimate behavior. In this study, ultimate behavior of steel cable-stayed bridges was studied using rational ultimate analysis method. Nonlinear equivalent truss element and nonlinear frame element were used for modeling the cable, girder and mast. Moreover, refined plastic hinge method was adopted for considering the material nonlinearity of steel members. In this study, the 2-step analysis method was used. Before live load analysis, initial shape analysis was performed in order to consider the dead load condition. For investigation of the ultimate behavior of steel cable-stayed bridges, analysis models which span length is 920.0 m were used. Radiating type and fan type were considered as the cable-arrangement types. With various quantitative evidences such as load-displacement curves, deformed shapes, locations of the yield point or region, bending moment distribution and so on, the ultimate behavior of steel cable-stayed bridges was investigated and described in this paper.