• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.19 no.4
• /
• pp.1-8
• /
• 2005

Plasma researches using parallel-plate electrodes are widely used in semiconductor application such as etching and thin film deposition. Therefore, a quantitative understanding and control of plasma behavior are becoming increasingly necessary because their important applications and simulation techniques have been actively carried out in order to solve such problems above. In this paper, we developed a two-dimensional(2D) self-consistent fluid model, because 2D models can deal with real reactor geometries. The fluid model is based on particle continuity equations for taking account of an electrode system in a cylindrical geometry. An pure Ar gas was used at 500[mTorr] and radio-frequency (13.56(MHz)). Four models were simulated under the different electrode geometries which have chamber widths of 5.25, 6.0, 8.0, and 10.0[cm] and we compared their results with each other. Plasma uniformity and a do self-bias voltage were also discussed.

• Journal of Korea Multimedia Society
• /
• v.12 no.11
• /
• pp.1692-1700
• /
• 2009

This paper proposes the direction distribution of surface normal vectors as a feature descriptor of three-dimensional models. Proposed the feature descriptor handles rotation invariance using a principal component analysis(PCA) method, and performs mesh simplification to make it robust and nonsensitive against noise addition. Our method picks samples for the distribution of normal vectors to be proportional to the area of each polygon, applies weight to the normal vectors, and applies interpolation to enhance discrimination so that the information on the surface with less area may be less reflected on composing a feature descriptor. This research measures similarity between models with a L1-norm in the probability density histogram where the distances of feature descriptors are normalized. Experimental results have shown that the proposed method has improved the retrieval performance described in an average normalized modified retrieval rank(ANMRR) by about 17.2% and the retrieval performance described in a quantitative discrimination scale by 9.6%~17.5% as compared to the existing method.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.22 no.1
• /
• pp.29-35
• /
• 2014

This paper aims to obtain the effect of lightweight on Radius rod. The response surface method used in the paper is the statistical method. Optimization method is performed with the Radius rod using the lightweight material. Structural analysis is executed by using the ANSYS program to find static and dynamic responses. From this study result, it is verified that the response surface method has the advantage of optimum value in comparison with other optimization methods. The analysis is also performed by response surface method to derive optimal design values. Steel model and aluminium initial model are obtained by finite element analysis to clarify design criteria and the results are compared with three models each other. The weights can be reduced by optimal design analysis results of these models similar to those of existing products. The quantitative goals in this study can also attained through results of fatigue analyses. The reliability on optimal design of Radius rod can be improved by use of structural and fatigue analysis results.

• Asian-Australasian Journal of Animal Sciences
• /
• v.30 no.1
• /
• pp.8-19
• /
• 2017

Objective: A whole genome association study was conducted to identify single nucleotide polymorphisms (SNPs) with additive and dominant effects for growth and carcass traits in Korean native cattle, Hanwoo. Methods: The data set comprised 61 sires and their 486 Hanwoo steers that were born between spring of 2005 and fall of 2007. The steers were genotyped with the 35,968 SNPs that were embedded in the Illumina bovine SNP 50K beadchip and six growth and carcass quality traits were measured for the steers. A series of lack-of-fit tests between the models was applied to classify gene expression pattern as additive or dominant. Results: A total of 18 (0), 15 (3), 12 (8), 15 (18), 11 (7), and 21 (1) SNPs were detected at the 5% chromosome (genome) - wise level for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area (LMA) and marbling score, respectively. Among the significant 129 SNPs, 56 SNPs had additive effects, 20 SNPs dominance effects, and 53 SNPs both additive and dominance effects, suggesting that dominance inheritance mode be considered in genetic improvement for growth and carcass quality in Hanwoo. The significant SNPs were located at 33 quantitative trait locus (QTL) regions on 18 Bos Taurus chromosomes (i.e. BTA 3, 4, 5, 6, 7, 9, 11, 12, 13, 14, 16, 17, 18, 20, 23, 26, 28, and 29) were detected. There is strong evidence that BTA14 is the key chromosome affecting CWT. Also, BTA20 is the key chromosome for almost all traits measured (WWT, YWT, LMA). Conclusion: The application of various additive and dominance SNP models enabled better characterization of SNP inheritance mode for growth and carcass quality traits in Hanwoo, and many of the detected SNPs or QTL had dominance effects, suggesting that dominance be considered for the whole-genome SNPs data and implementation of successive molecular breeding schemes in Hanwoo.

• Advances in Computational Design
• /
• v.3 no.4
• /
• pp.367-384
• /
• 2018

The consideration of constructability issues at the design stage can lead to improved construction performance with smooth project delivery and savings in time and money. Empirical studies demonstrate the value obtained by integrating construction knowledge with the building design process, and its benefits for owners, contractors and designers. However, it is still a challenge to implement the concept into current design practice. There is a need for a decision support tool to aid designers in reviewing their design constructability, deploying current technological tools, such as BIM. Such tools are beneficial at the conceptual design stage when there is a room to improve the design significantly with less incurred cost. This research investigates how current process- and object-oriented models can be used to assess design constructability. It proposes a BIM-based model using embedded information within the design environment to conduct the assessment. The modelling framework is demonstrated in four key parts; namely, the conceptual design model, the constructability assessment model, the assessment process model and the decision-making phase. Each is associated with a set of components and functions that contribute towards the targeted constructability assessment outcomes. The proposed framework is the first to combine a numerical assessment system and a rule-based system, allowing for both quantitative and qualitative approaches. The modelling framework and its implementation through a prototype are described in this paper. It is believed that this framework is the first to enable users to transfer their construction knowledge and experience directly into a design platform linked to BIM models. The assessment criteria can be customised by the users who can reflect their own constructability preferences into various specialised profiles that can be added to the constructability assessment model. It also allows for the integration of the assessment process with the design phase, facilitating the optimisation of constructability performance from the early design stage.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.6
• /
• pp.2823-2828
• /
• 2012

Objective: To explore a new model of in-situ xenograft lymphangiogenesis of human colonic adenocarcinomas in nude mice. Method: On the basis of establishing subcutaneous xenograft lymphangiogenesis model of human colonic adenocarcinoms, in-situ xenografts were established through the in situ growth of the HT-29 human colonic adenocarcinoma cell line in nude mice. The numbers of lymphangiogenic microvessels, the expression of lymphatic endothelial cell markers lymphatic vessel endothelial hyaloronic acid receptor-1 (LYVE-1), D2-40 and the lymphatic endothelial growth factors vascular endothelial growth factor-C (VEGF-C), -D (VEGF-D) and receptor-3 (VEGFR-3) were compared by immunohistochemical staining, Western bolt and quantitative RT-PCR in xenograft in-situ models. Results: Some microlymphatics with thin walls, large and irregular or collapsed cavities and increased LMVD, with strong positive of LYVE-1, D2-40 in immunohistochemistry, were observed, identical with the morphological characteristics of lymphatic vessels and capillaries. Expression of LYVE-1 and D2-40 proteins and mRNAs were significantly higher in xenograpfts in-situ than in the negative control group(both P<0.01). Moreover, the expression of VEGF-C, VEGF-D and VEGFR-3 proteins and mRNAs were significantly higher in xenografts in-situ (both P<0.01), in conformity with the signal regulation of the VEGF-C,-D/VEGFR-3 axis of tumor lymphangiogenesis. Conclusions: In-situ xenografts of a human colonic adenocarcinoma cell line demonstrate tumor lymphangiogenesis. This novel in-situ animal model should be useful for further studying mechanisms of lymph node metastasis, drug intervention and anti-metastasis therapy in colorectal cancer.

• The Korean Journal of Pesticide Science
• /
• v.12 no.1
• /
• pp.9-17
• /
• 2008

QSARs (Quantitative structure-activity relationships) between a series of new cyclohexanedione derivatives (5-benzofuryl-2-[1-(alkoxyimino)-alkyl]-3-hydroxycyclohex-2-en-1-ones) and their herbicidal activity against Rice plant (Oryza sativa L.) and Barnyard grass (Echinochloa crus-galli.) were discussed quantitatively using 2D-QSAR and holographic (H) QSAR methods. Generally, the HQSAR models have better predictability and fitness than the 2D-QSAR models. The herbicidal activities against Barnyard grass with 2D-QSAR II model were dependent upon Balaban indice (BI) of molecule and hydrophobicity of $R_1$ and $R_3$ group. And also, the $R_3=ethyl$ group, according to the information of the optimized HQSAR IV model, was more contribute to the herbicidal activities against Rice plant, while the 5-(cyclohex-3-enyl)-2,3-dihydrobenzofuran ring part was not contribute to the herbicidal activities against two plants.

• Journal of the military operations research society of Korea
• /
• v.37 no.1
• /
• pp.11-25
• /
• 2011

This study analyzes the quantitaive effect of 155M artillery ammunition procurement from third party countries in the wartime using simulation. First, we study the concept of ammunition supply, procurement plan, transportation plan in the wartime and logistics support from third party countries. We then study the ammunition support possibility from third party countries. Secondly, we make a basic model on the sea-lift from Korea to U.S in the wartime using simulation followed by making comparative models on the sea-lift from Korea to U.S and third party countries. Finally, we analyze models on the completion date of ammunition transportation and the ammunition amount of each operation step. We then execute the sensitivity analysis on the ammunition amount from third party countries. In cocclusion, ammunition prcurement from third party countreis more supply 10% than basic model.

• Bulletin of the Korean Chemical Society
• /
• v.34 no.12
• /
• pp.3553-3558
• /
• 2013

The three dimensional-quantitative structure activity relationship (3D-QSAR) studies on chemical features of pyridine-2-amines in the external region of c-Met active site (ER chemical features of pyridine-2-amines) were conducted by docking, comparative molecular field analysis (CoMFA), and topomer CoMFA methods. The CoMFA model obtained the partial least-squares (PLS) statistical results, cross-validated correlation coefficient ($q^2$) of 0.703, non cross-validated correlation coefficient ($r^2$) of 0.947 with standard error of estimate (SEE) of 0.23 and the topomer CoMFA obtained $q^2$ of 0.803, $r^2$ of 0.940, and SEE of 0.24. Further, the test set was applied to validate predictive abilities of models, where the predictive $r^2$ ($r{^2}_{pred}$) for CoMFA and topomer CoMFA models were 0.746 and 0.608, respectively. Each contribution of ER chemical features of pyridine-2-amines to the inhibitory potency showed correlation coefficients, $r^2$ of 0.670 and 0.913 for two core parts, 3-(benzo[d]oxazol-2-yl)pyridine-2-amine and 3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy) pyridine-2-amine, respectively, with corresponding experimental $pIC_{50}$.

• Journal of computational fluids engineering
• /
• v.20 no.1
• /
• pp.65-76
• /
• 2015

In this study, the natural convection phenomenon of the air side and the forced convection phenomenon of the oil side were simulated in the radiator through a 3-D numerical analysis, and the total heat released by the oil side into the radiator heating plate and then to the air side was evaluated. Also, a quantitative analysis was carried out on the effect of each thermal resistance on the overall heat transfer coefficient through a 1-D thermal circuit analysis on the heat transfer mechanisms of the radiators considered in this study. In addition, for the diverse shapes of the heating plates considered in this study, the pressure drops of the oil side were quantitatively compared and evaluated. The temperatures at the air side and the oil side outlets of the radiators with 8 different fin shapes considered in this study had almost similar values showing a difference of +/-3% and, accordingly, the total heat transfer also showed similar heat dissipation performance in all the models. As a result of the 1-D thermal circuit analysis, in all the models considered in this study, while the thermal resistance of the air side accounted for 92% to 96% of the total, that of the oil side was 5 to 7%, and that of the heating plate showed a very small value of 0.02%.