• Title/Summary/Keyword: quantitative evaluation method

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Captopril $^{99m}Tc-DTPA$ Renal Scintigraphy in Diagnosis of Renovascular Hypertension (신혈관성 고혈압의 진단에 있어서 캅토프릴 신스캔의 의의)

  • Yang, Hyung-In;Lee, Dong-Soo;Kim, Sung-Chul;Bae, Sang-Kyun;Choi, Chang-Woon;Chung, June-Key;Kim, Suhng-Gwon;Lee, Myung-Chul;Lee, Jung-Sang;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.2
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    • pp.312-317
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    • 1992
  • To evaluate the sensitivity and specificity of captopril renal scan for renovascular hypertension, we employed the captopril renal scan in conjunction with renal angiography in 81 patients, 159 kidneys, who were referred to evaluate the cause of hypertension. We defined the renovascular hypertension by the criteria of demonstration of renal artery stenosis by angiography, and improvement or cure of hypertension by revascularization. Visual and quantitative evaluation of $^{99m}Tc-DTPA$ renal scan was peformed pre and post captopril administration. The prevalence rate of renovascular hypertension was 40% in comparing with renal angiography, and 70% in confirmed cases. The causes of renovascular hypertension in 81 patients were Takayasu's arteritis, fibromuscular dysplasia, atherosclerosis, essential hypertension, chronic pyetonephritis etc. The sensitivity and specificity of captopril renal scan in comparing with renal angiography were 80%, 86.5%, respectively and also 84.2%, 72.6% in confirmed cases of renovascular hypertension, respectively. The causes of false negative cases were nonfunctioning kidney due to complete obstruction or long duration of disease in basal scan, segmental branch artery stenosis, unknown causes, and suspicious true negative cases without confirmation. The false positive cases were abdominal aortic stenosis or aneurysm, dehydration, unknown causes, and suspicious true positive cases. We conclude that captopril renal scintigraphy is highly sensitive, reasonably specific diagnostic method and comparable to other techniques very favorably.

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Seasonal Effects Removal of Unsupervised Change Detection based Multitemporal Imagery (다시기 원격탐사자료 기반 무감독 변화탐지의 계절적 영향 제거)

  • Park, Hong Lyun;Choi, Jae Wan;Oh, Jae Hong
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.36 no.2
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    • pp.51-58
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    • 2018
  • Recently, various satellite sensors have been developed and it is becoming more convenient to acquire multitemporal satellite images. Therefore, various researches are being actively carried out in the field of utilizing change detection techniques such as disaster and land monitoring using multitemporal satellite images. In particular, researches related to the development of unsupervised change detection techniques capable of extracting rapidly change regions have been conducted. However, there is a disadvantage that false detection occurs due to a spectral difference such as a seasonal change. In order to overcome the disadvantages, this study aimed to reduce the false alarm detection due to seasonal effects using the direction vector generated by applying the $S^2CVA$ (Sequential Spectral Change Vector Analysis) technique, which is one of the unsupervised change detection methods. $S^2CVA$ technique was applied to RapidEye images of the same and different seasons. We analyzed whether the change direction vector of $S^2CVA$ can remove false positives due to seasonal effects. For the quantitative evaluation, the ROC (Receiver Operating Characteristic) curve and the AUC (Area Under Curve) value were calculated for the change detection results and it was confirmed that the change detection performance was improved compared with the change detection method using only the change magnitude vector.

Ecological Characteristics of Actinomycetes from Mercury and Chrome Polluted Soil (수은, 6가크롬 오염토양으로부터 분리된 방선균군의 생태학적 특성)

  • Cho Min-Hye;Han Sang-Mi;Baek Ha-Ju;Whang Kyung-Sook
    • Korean Journal of Environmental Biology
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    • v.24 no.1 s.61
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    • pp.38-45
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    • 2006
  • Ecological characteristics of microbial populations inhabiting heavy metal polluted soil were investigated. The samples were collected from 293 sites around an factory and industry at Gyeoungsangbuk-do. We measured the contents of seven heavy metal elements (Cd, Cu, As, Hg, Pb, $Cr^{6+}$, CN), seven sites have been seriously contaminated by mercury and chrome. A quantitative evaluation of microbial populations in mercury and chrome contaminated soil was examined by using plate count method. Bacterial numbers in polluted soil samples ranged from $7.4X10^5\;to\;9.3X10^7\;cfu\;g^{-1}$, about $10\sim100$ fold less than the count for the unpolluted soil. Moulds were not detected in chrome polluted soil. The log values of actinomycetes of each contaminated soil samples were log ranged from 6.18 to 7.52. The ratio of actinomycetes was similar to unpolluted soil. The investigation showed actinomycetes to be the major microbial population inhabiting the mercury and chrome polluted soil. Thirty-one isolates among the total isolates were examined for antibacterial activity. These isolates were identified based on a phylogenetic analysis using 16S rRNA gene nucleotide sequences, they were categorized in three major phylogenetic groups, belong to the Streptomyces (6 strains), Saccharopolyspora (3 strains), Nocardiodes (1 strain). On the phylogenetic tree, the clade consisting of five isolates were distantly related to all of the established Streptomycetes genera, indicating the possibility as members of new species.

Development and Evaluation of a SYBR Green Real-time PCR Assay for Canine Cytokine Gene Expression (SYBR Green 실시간 역전사 중합효소연쇄반응을 이용한 개 싸이토카인 유전자 발현의 정량)

  • Yu, Do-Hyeon;Ihn, Dong-Chul;Park, Chul;Park, Jin-Ho
    • Journal of Veterinary Clinics
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    • v.27 no.5
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    • pp.508-513
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    • 2010
  • Cytokines are important mediators of the immune response, and quantitating cytokine mRNA is a highly sensitive and attractive method for measuring cytokine production. The objective of the current study was to develop and validate a SYBR green quantitative real-time reverse transcriptase PCR (qRT-PCR) assay for measuring canine cytokine mRNA. The optimal annealing temperatures ($T_a$) of the designed primers were $62^{\circ}C$ for interleukin (IL)-$1{\beta}$, IL-6 and IL-10; $60^{\circ}C$ for glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and tumor necrosis factor (TNF)-${\alpha}$; and $58^{\circ}C$ for high mobility group box 1 (HMGB1). Primer efficiencies of all primers calculated for standard curve samples were between 97.1% and 102.6%. No evidence of secondary structure or primer-dimer formation was seen via melt-curve analysis or gel electrophoresis. The developed qRT-PCR assays are highly specific and sensitive and can be used to quantify gene expression levels of canine cytokines.

Efficacy of Enrofloxacin and Silver Sulfadiaznine Topical Otic Suspension for the Treatment of Canine Otitis Externa (개 외이염에 대한 Enrofloxacin과 Silver Sulfadiazine 국소제제의 치료효과)

  • Bae, Seulgi;Kim, Byeongmok;Choi, Sungwon;Sin, Hui-Ju;Lee, Young-Ju;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.30 no.3
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    • pp.172-177
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    • 2013
  • The aim of this study was to evaluate the in vivo and in vitro efficacy of enrofloxacin-silver sulfadiazine (Baytril$^{(R)}$ otic, Bayer, USA) for the treatment of otitis externa in dogs. Twenty-four dogs with otitis externa were included in this double-blinded, randomized study. The experimental group was treated with the Baytril$^{(R)}$ otic and the distilled water was applied to the control group. Both groups were administered each solution twice daily for 7 days and next 7 days off treatment. On days 0, 7 and 14, clinical signs, bacteriological and fungal counts were graded using semi-quantitative scales, respectively. For the evaluation of in vitro efficacy of Baytril$^{(R)}$ otic, we also performed Minimal Inhibitory Concentration (MIC) test by agar dilution method against Staphylococcus pseudintermedius, Pseudomonas aeruginosa and Malassezia pachydermatis. In the experimental group, the sum of clinical scores was decreased 81.0% and microbial scores were significantly reduced 87.0% at days 14, compared with day 0. The results of MIC testing were showed the concentration of enrofloxacin and silver sulfadiazine in Baytril$^{(R)}$ otic is high enough to kill for 3 infectious agents. No adverse reactions were observed in any of the dogs during this study. These results suggest that Baytril$^{(R)}$ otic are efficient and safe treatment for canine otitis externa.

Biodiversity and Phylogenetic Analysis of Streptomyces Collected from Bamboo Forest Soil (대나무 산림토양으로부터 수집한 Streptomyces 속 방선균의 계통학적 다양성)

  • Lee, Hyo-Jin;Whang, Kyung-Sook
    • Korean Journal of Microbiology
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    • v.46 no.3
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    • pp.262-269
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    • 2010
  • To investigate a quantitative evaluation of the actinobacteria, we have collected samples from various kinds of bamboo forest soil. Each different layers contained $2.7{\times}10^6-2.7{\times}10^8$ CFU/g of actinobacteria which was the highest in litter layers of Sasa boreali forest soil. We obtained 330 actinobacteria from different layers of bamboo forest soil; litter (100 strains), humus (70 strains), and rhizosphere soil (160 strains). Based on the colony morphology (aerial mycelium, substrate mycelium, and soluble pigment), isolates were divided into thirty-six groups and we selected 50 representative isolates. 16S rRNA gene sequence analysis showed Streptomyces was major actinobacteria (94%) and they were categorized as cluster I (2 strains), II (35 strains), III (6 strains), and IV (7 strains), respectively. The diversity index of 50 Streptomyces collected from the bamboo forest soil was calculated with the Shannon-Wiener method. Bamboo litter showed higher diversity index level of 3.33 than that of humus and rhizosphere soil. Also, antibiotic activities of our isolates were investigated against Botrytis cinerea, Xanthomonas campestris, Xanthomonas axonopodis pv. vesicatoria, and Bacillus cereus and found in 74, 16, 25, and 24 strains, respectively.

Application of Proteolytic Enzymes in Fruits for Meat Tenderization (과일에 존재하는 단백질 분해효소의 식육연화효과에 관한 연구)

  • 배영희;노정해
    • Korean journal of food and cookery science
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    • v.16 no.4
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    • pp.367-371
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    • 2000
  • In order to study the tenderizing effect of proteolytic enzymes in fruits, beef(M. semimembranosus) was marinated with meat sauce containing each fruit juices. After cooking, the shear force was measured by Rheometer and evaluated the sensory properties of beef by quantitative descriptive analysis method. The results are as follows: 1. The combination ratio of meat sauce:water was 2:1 with pH 5.0∼5.5 showed the max. tenderness. 2. As a result of shear force test, the decrease of shear force was pineapple>papaya>fig>kiwifruit>pear: especially, pineapple, papaya and fig tendered the beef significantly comparing with pear and kiwifruit at p<0.001. 3. The tendering effect of pineapple and papaya on the meat showed significant difference (p<0.01) comparing with pear in tenderness and overall acceptability by sensory evaluation; and there was a significant difference between pear and papaya in taste (p<0.05). 4. There was highly significant correlation between mechanical tenderness and sensory properties: correlation of fruit and mechanical tenderness was -.877(p<0.01); between mechanical tenderness and overall acceptability, r = .532(p<0.01); between fruit and sensory tenderness, r = .495(p<0.01); between mechanical tenderness and sensory tenderness, r = .490(p<0.01). At p<0.05, between taste and juiciness, r = .208.

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Evaluation of Accuracy and Utilization of the Drone Photogrammetry for Open-pit Mine Monitoring (노천광산 모니터링을 위한 드론 사진측량의 정확도 및 활용성 평가)

  • Park, Joon-Kyu;Um, Dae-Yong
    • Journal of Digital Convergence
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    • v.17 no.12
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    • pp.191-196
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    • 2019
  • The development of open-pit mines leads to large-area topographical changes in highland forests and can lead to severe deterioration of forests, requiring continuous monitoring. The drone photogrammetry is performed at a lower altitude than the existing manned aerial photogrammetry, and thus has a relatively high accuracy. The purpose of this study is to construct spatial information of large open pit mine using drone photogrammetry and to evaluate the accuracy and utilization of the results. The accuracy of the drone photogrammetric results was 0.018 ~ 0.063m in the horizontal direction and 0.027m ~ 0.088m in the vertical direction. These results satisfy the permissible accuracy of 1: 1,000 digital topographic map and it can be used for open mine monitoring. The geospatial information of the open pit mine can be used in various ways, and it can be used to monitor the quantitative change of a specific area for time series change through data management by periodic data acquisition. If drone photogrammetry is applied to open-pit mine monitoring in the future, work time and cost can be greatly reduced compared to the conventional GNSS or total station method, and the work efficiency can be greatly improved because more visible data can be generated.

A Survey on the Persons in Charge for Economic Estimation Analysis and Improvement of BTL Projects (BTL사업의 경제성 평가 현황조사 및 개선을 위한 실무자 설문조사연구)

  • Lee, Chun-Kyong;Cho, Bong-Ho;Park, Tae-Keun
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.4
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    • pp.73-80
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    • 2007
  • As BTL(Build-Transfer-Lease) private investment business benchmarking PHI(Private Finance Initiative) of USA and Japan is introduces to Korea since 2005, as a part of supplying high leveled public service and early expanding required facilities for SOC, Value for Money on private investment business from treasury investment business at the beginning gets to be needed. Accordingly, this survey has been conducted in order to analyse BTL projects status, propriety of economic analysis method(VFM analysis, calculation of estimated business expenses, valuation of bidding price, etc.) by business advance phases from the viewpoint of person in charge, necessity of improvement and alternative plants. As the result of conducting cross tabulation analysis and correlation analysis by occupational group, BTL project advance phases and alternative plans for improvement, it is necessary ye prepare standardized service level against business expense and basis for calculating and evaluation operation expenses. Based on the necessity of quantitative analysis (LCC analysis) of VFM, standard for calculating management, maintenance and administration expenses is required. In addition, reliable economic valuation system considering domestic BTL environment should be setup, for business efficiency.

A Study on the Development of Urine Analysis System using Strip and Evaluation of Experimental Result by means of Fuzzy Inference (스트립을 이용한 요분석시스템의 개발과 퍼지추론에 의한 검사결과 평가에 관한 연구)

  • Jun, K. R.;Lee, S. J.;Choi, B. C.;An, S. H.;Ha, K.;Kim, J. Y.;Kim, J. H.
    • Journal of Biomedical Engineering Research
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    • v.19 no.5
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    • pp.477-486
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    • 1998
  • In this paper, we implemented the urine analysis system capable of measuring a qualitative and semi-quantitative and assay using strip. The analysis algorithm of urine analysis was adopted a fuzzy logic-based classifiers that was robust to external error factors such as temperature and electric power noises. The spectroscopic properties of 9 pads In a strip were studied to developing the urine analysis system was designed for robustnesss and stability. The urine analysis system was consisted of hardware and software. The hardware of the urine analysis system was based on one-chip microprocessor, and Its peripherals which composed of optic modulo, tray control, preamplifier, communication with PC, thermal printer and operating status indicator. The software of the urine analysis system was composed of system program and classification program. The system program did duty fort system control, data acquisition and data analysis. The classification program was composed of fuzzy inference engine and membership function generator. The membership function generator made triangular membership functions by statical method for quality control. Resulted data was transferred through serial cable to PC. The transferred data was arranged and saved be data acquisition program coded by C+ + language. The precision of urine analysis system and the stability of fuzzy classifier were evaluated by testing the standard urine samples. Experimental results showed a good stability states and a exact classification.

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