• Title/Summary/Keyword: quality deviation

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A Study on Standardization of Shinbaro Pharmacopuncture Using Herbal Medicines Identification Test and HPLC-DAD (신바로 약침의 한약재 확인시험 및 HPLC-DAD를 통한 표준화 연구)

  • Lee, Jin Ho;Kim, Min Jeong;Lee, Jae Woong;Kim, Me Riong;Lee, In Hee;Kim, Eun Jee
    • Journal of Acupuncture Research
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    • v.32 no.2
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    • pp.1-9
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    • 2015
  • Objectives : The present study was an evaluation and standardization of herbal components in order to establish the efficacy and safety of Shinbaro pharmacopuncture. Methods : Among the raw materials of Shinbaro pharmacopuncture, the components Cibotii Rhizoma, Eucommiae Cortex, and Ledebouriellae Radix were assessed through ingredient verification experiments using thin-layer chromatography(TLC) and ultraviolet rays(UV) lamps. In addition, we standardized Acanthopanacis Cortex and Achyranthis Radix through validation using high performance liquid chromatograph-diode array detector(HPLC-DAD). Results : As result appeared a blue-white fluorescence under ultraviolet rays; changed to dark green after adding 1 % ferric chloride solution(due to Cibotii Rhizoma), and presented a yellow-green fluorescence when mixed with an ethyl ether under UV lamps by way of the ethyl ether layer, confirming Eucommiae Cortex. Ledebouriellae Radix was confirmed as dark brown spots at Rf values of 0.56 and 0.71 using TLC. Additionally, Acanthopanacis Cortex and Achyranthis Radix HPLC test results showed that linearity was $R^2{\geq}0.99$, and detection limit and quantitation limit were 0.23 to $1.29{\mu}g/mL$, and 0.71 to $3.90{\mu}g/mL$, respectively. Furthermore, precision and accuracy were confirmed to have relative standard deviation(RSD) values of 0.10 to 1.89 % and 96.19 to 103.72 %, respectively. Shinbaro pharmacopuncture did not have any overlapping or interference from other peaks in detection under the abovementioned analysis conditions. Conclusions : In conclusion, we confirmed that maintenance of Shinbaro pharmacopuncture validity was possible by means of quality control of Cibotii Rhizoma, Eucommiae Cortex, and Ledebouriellae Radix through ingredient identification and Acanthopanacis Cortex and Achyranthis Radix through high performance liquid chromatograph(HPLC) analysis. Further, we hope to contribute to the development strategy of herbal industry acupuncture.

A Study of the Casual Wear Purchase Behavior of the Adult Males (성인남성의 캐주얼의복 구매행동에 관한 연구)

  • 신수윤;김영덕
    • The Research Journal of the Costume Culture
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    • v.7 no.4
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    • pp.99-110
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    • 1999
  • In order to help the marketers of the men\`s casual wear brands establish the marketing strategies to their target consumers, it is the purpose of this study to investigate on the variables affecting the casual wear purchase behavior of men in twenties, thirties and forties, and to clarify the differences of casual wear purchase behavior according to their age, The subjects were 429 men in their twenties, thirties and forties living in Seoul and data were analyzed by frequency, percentage, mean and standard deviation, x², ANOVA and Duncan\`s test. The results were as follows : (1) Significant differences were found among men in twenties, thirties and forties according to the self-image. Men in forties favored the conservative and not-noticeable image of casual wear, however, men in twenties and thirties favored those of the active, sexy, and distinctive image. (2) Significant differences were found among men in twenties, thirties and forties according to the importance of the store attributes such as convenience of transportation and parking place, clothing in vogue, and various merchandise. Men in thirties and forties put more importance on convenience of transportation and parking place. Men in forties put more importance on various merchandise than men in twenties and thirties. (3) Significant differences were found among men in twenties, thirties and forties according to general purchase behavior of casual wear. * Differences of the use of information according to age Majority of the men consulted the T.V., radio and people in their boundaries * Differences of the clothing purchase frequency according to age Men in twenties buy more clothing than other age groups. Men in twenties buy the clothing every one month and every three months and men in thirties and forties buy the clothing every three months and every six months. * Differences of the shopping day according to age Majority of the men buy the clothing on Saturday and Sunday. However men in twenties buy the clothing more on weekdays than other age groups. * Differences of the shopping place according There were not significant differences among three different age groups and majority of the men found out to utilize the department store. * Differences of the influence of the partners according to age Men in twenties found out to rely on their own decisions but men in thirties and forties found out to depend on their wives(loves). * Differences of the selection standards of casual wear according to age There were not significant differences according to age and adult males found out to select the casual wear by design, quality price in sequence.

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A study of trabecular bone strength and morphometric analysis of bone microstructure from digital radiographic image (디지털방사선영상에서 추출한 해면질골의 강도와 미세구조의 형태계측학적 분석에 대한 연구)

  • Han Seung-Yun;Lee Sun-Bok;Oh Sung-Ook;Heo Min-Suk;Lee Sam-Sun;Choi Soon-Chul;Park Tae-Won;Kim Jong-Dae
    • Imaging Science in Dentistry
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    • v.33 no.2
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    • pp.113-119
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    • 2003
  • Purpose : To evaluate the relationship between morphometric analysis of bone microstructure from digital radiographic image and trabecular bone strength. Materials and Methods : One hundred eleven bone specimens with 5 mm thickness were obtained from the mandibles of 5 pigs. Digital images of specimens were taken using a direct digital intraoral radiographic system. After selection of ROI (100 × 100 pixel) within the trabecular bone, mean gray level and standard deviation were obtained. Fractal dimension and the variants of morphometric analysis (trabecular area, periphery, length of skeletonized trabeculae, number of terminal point, number of branch point) were obtained from ROI. Punch sheer strength analysis was performed using Instron (model 4465, Instron Corp., USA). The loading force (loading speed 1 mm/min) was applied to ROI of bone specimen by a 2 mm diameter punch. Stress-deformation curve was obtained from the punch sheer strength analysis and maximum stress, yield stress, Young's modulus were measured. Results: Maximum stress had a negative linear correlation with mean gray level and fractal dimension significantly (p<0.05). Yield stress had a negative linear correlation with mean gray level, periphery, fractal dimension and the length of skeletonized trabeculae significantly (p < 0.05). Young's modulus had a negative linear correlation with mean gray level and fractal dimension significantly (p < 0.05). Conclusions : The strength of cancellous bone exhibited a significantly linear relationship between mean gray level, fractal dimension and morphometric analysis. The methods described above can be easily used to evaluate bone quality clinically.

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Development of the Hippocampal Learning Algorithm Using Associate Memory and Modulator of Neural Weight (연상기억과 뉴런 연결강도 모듈레이터를 이용한 해마 학습 알고리즘 개발)

  • Oh Sun-Moon;Kang Dae-Seong
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.43 no.4 s.310
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    • pp.37-45
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    • 2006
  • In this paper, we propose the development of MHLA(Modulatory Hippocampus Learning Algorithm) which remodel a principle of brain of hippocampus. Hippocampus takes charge auto-associative memory and controlling functions of long-term or short-term memory strengthening. We organize auto-associative memory based 3 steps system(DG, CA3, CAl) and improve speed of learning by addition of modulator to long-term memory learning. In hippocampal system, according to the 3 steps order, information applies statistical deviation on Dentate Gyrus region and is labelled to responsive pattern by adjustment of a good impression. In CA3 region, pattern is reorganized by auto-associative memory. In CAI region, convergence of connection weight which is used long-term memory is learned fast by neural networks which is applied modulator. To measure performance of MHLA, PCA(Principal Component Analysis) is applied to face images which are classified by pose, expression and picture quality. Next, we calculate feature vectors and learn by MHLA. Finally, we confirm cognitive rate. The results of experiments, we can compare a proposed method of other methods, and we can confirm that the proposed method is superior to the existing method.

Validation of the Korean Version of the Bronchiectasis Health Questionnaire

  • Kim, Hyun Kuk;Lee, Hyun;Kim, Sang-Heon;Choi, Hayoung;Lee, Jae Ha;Lee, Jae Seung;Lee, Sei Won;Oh, Yeon-Mok
    • Tuberculosis and Respiratory Diseases
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    • v.83 no.3
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    • pp.228-233
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    • 2020
  • Background: The Bronchiectasis Health Questionnaire (BHQ) is a simple and repeatable, self-reporting health status questionnaire for bronchiectasis. We have translated the original version of the BHQ into Korean using a standardized methodology. The purpose of this study was to assess the validity of the Korean version of the BHQ (K-BHQ) with Korean patients. Methods: Stable state patients with bronchiectasis from two academic hospitals were enrolled in this study. The validity was assessed by investigating the relationship between the K-BHQ scores and the Korean version of the Chronic Obstructive Pulmonary Disease Assessment Test (K-CAT) scores. We also investigated the relationship between the K-BHQ scores and other variables of the modified Medical Research Council's (mMRC) dyspnea scale, lung function, and exacerbations. Results: A total of 126 patients with bronchiectasis were enrolled. The mean age was 64.3 (standard deviation [SD], 9.7). Women comprised 53.2% of the patients. The mean forced expiratory volume in one second (FEV1) was 60% of the predicted value (SD, 18.9%); the mean K-CAT score was 17.6 (SD, 9.1). The K-BHQ scores correlated strongly with the K-CAT scores (r=-0.656, p<0.001). There was significant correlation between the K-BHQ scores and the mMRC dyspnea scale (ρ=-0.409, p<0.001), FEV1 (r=0.406, p<0.001), and number of exacerbations requiring hospitalization (ρ=-0.303, p=0.001). Conclusion: The K-BHQ is valid for assessing the health-related quality of life or health status of Korean bronchiectasis patients.

Analyses of Consumer Preferences and Perceptions Regarding Activation of Yacht Tourism Industry (요트관광산업의 활성화를 위한 소비자 선호도 및 인식도 조사)

  • Cho, Woo-Jeong
    • Journal of Navigation and Port Research
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    • v.36 no.5
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    • pp.401-407
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    • 2012
  • The purpose of this study was to examine the preferences to yacht tourism and perceptions to importance of yacht tourism industry's activation strategies from consumers perspectives. In order to such a purpose, this study employed survey methodology with a total of 300 visitors to yacht facility and beach located in B metropolitan city. With 265 usable questionnaires, data collected were analyzed using descriptive statistics such as frequency, percentage, mean and standard deviation. Accordingly, following findings were derived from current study. First, 32% of participants had yacht tourism experiences and more than 64% of them had willing to purchase yacht tourism products in the future, which indicates optimistic increases in yacht tourism demand. In addition, amount of willingness to pay for yacht tourism was less than 100 thousand Won per day. Second, the most preferred product was a yacht training and experience program, and preferred time for yacht tourism was weekend and or vacation with the period of one day or one night and two days. The main motivation was to spend leisure time and enjoyment with accompanying persons of family or friend members. Third, consumers' restriction factors included high expenditures, time consuming and lack of various yacht tourism products but their selection attributes included low expenditures, associated tourism products and quality of yacht tourism products. Finally, the most important activation strategies included the development of yacht tourism products, building yacht tourism conditions and establishing marketing strategies, but the least important activation strategies from consumers views included policies, experts and facilities.

Determination of the Optimal Parameters in Data Processing for the Precision Geoid Construction (정밀 지오이드 구축을 위한 자료처리의 최적 변수 결정)

  • Lee, Ji-Sun;Kwon, Jay-Hyoun
    • Spatial Information Research
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    • v.17 no.3
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    • pp.397-404
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    • 2009
  • To solve the problems of distribution and quality on land gravity data, airborne gravity survey was performed in 2008 obtaining the airborne gravity data with accuracy of 1.56mGal. Since airborne gravity data is the obtained at the flight height, it is necessary to convert the airborne gravity data to the surface to combine various gravity data and compute precision geoid. In addition, Stokes' integral radius, Stokes' kernel and the radius of terrain effect computation should be optimally determined to calculate precision geoid. In this study, we made an effort to decide the optimal parameters based on the distribution and the characteristic of gravity data. Then, two geoid models were calculated using the selected parameters and the difference of geoid was calculated with mean of -16.95cm and the standard deviation of ${\pm}8.50cm$. We consider that this difference is due to the distribution and errors on the gravity data. For future work, the study on the effect of geoid with newly obtained land gravity data ship-borne gravity data and GPS/Leveling data should be conducted. Furthermore, the study on the downward continuation and terran effect calculation should be studied in detail for better precision geoid construction.

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A Job Analysis of Acute Care Hospitals' Formal Caregiver (급성기병원 간병인의 직무분석)

  • Kwon, Jin;Yang, Misook
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.639-651
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    • 2013
  • This study aims to improve caregiver's labor conditions, to provide a high-quality care service and to offer basic research information for developing a standardized job content of caregiver. The study establishes basic principles for a standardized job content with a literature review and then collects basic information of caregiver's task with an observation technique. The study based on the observation technique develops 11 job categories and 72 duty categories expected to do by the caregiver. The study examines acute care hospitals that provide joint care services in Seoul and Gyeonggi province. Sixty caregivers who work at these hospitals are carried out a survey regarding a specific task of caregiver, an importance of task and a frequency of task. Collected data is analyzed using statistical package SPSS 18.0, and descriptive statistics (frequency, percentage, average, standard deviation) is reported. An analysis of frequency is used to analyze target for research. From the collected information, tasks of caregiver are sorted into 10 job categories and 60 duty categories. As a result of the study, tasks of caregiver are sorted into 10 job categories and 68 duty categories based on the observations technique. One job category and four duty categories are added to the final survey based on an interview with professionals and officials in the field of care service but, one additional job category and four duty categories based on the interview are excepted from the result of the analysis. The interview with professionals and officials is nothing meaningful on the task analysis of caregiver.

Development of Frequency Weighing Sensor and Single Crystal Growth (새로운 무게센서 재발과 단결정성장(1))

  • Jang Y.N.;Sung N.H.;Chae S.C.;Bae I.K.;Kim I.J.
    • Korean Journal of Crystallography
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    • v.8 no.1
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    • pp.38-47
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    • 1997
  • A new weighing sensor for the automatic diameter control system of the crystal growth is developed in this study. This weighing sensor measures the frequency of the vibrating element which is lineally changing with respect to weight. The signal and the power of this system are transmitted without any physical contact, so that this sensor offers high accuracy and resolution. This system consists of a string, a sinusoidal wave generator, an automatic amplification adjusting circuit, signal transformers and a PCB. 4 kinds of programs are developed for checking DAC, weight calibration and controlling growth process. The measurements of the standard deviation and the resolution show $\pm0.10g$(measured at every second) and $5{\times}10^{-5}$, respectively, This weighing sensor is effective under high pres-sure of 200 atm, high temperature and vacuum condition. The weighing system can control the temperature in the accuracy of $\pm0.025^{\circ}C$ with the 'signal divider'. The optical quality single crystals of $(YGd)_3Sc_2Ga_3O_{12},\;Er-Y_3Sc_2Al_3O_{12},\;and\;Bi_{12}GeO_{20}$ have been grown by Czo-chralski method using this auto-diameter control system.

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A Study on 3D Model Building of Drones-Based Urban Digital Twin (드론기반 도심지 디지털트윈 3차원 모형 구축에 관한 연구)

  • Lim, Seong-Ha;Choi, Kyu-Myeong;Cho, Gi-Sung
    • Journal of Cadastre & Land InformatiX
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    • v.50 no.1
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    • pp.163-180
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    • 2020
  • In this study, to build a spatial information infrastructure, which is a component of a smart city, a 3D digital twin model in the downtown area was built based on the latest spatial information acquisition technology, the drone. Several analysis models were implemented by utilizing. While the data processing time and quality of the three types of drone photogrammetry software are different, the accuracy of the construction model is ± 0.04 in the N direction and ± 0.03m in the E direction. In the m and Z directions, ± 0.02m was found to be less than 0.1m, which is defined as the allowable range of surveying performance and inspection performance for the boundary point in the area where the registration of the boundary point registration is executed. 1: 500 to 1 of the aerial survey work regulation: The standard deviation, which is the error limit of the photographic reference point of the 600 scale, appeared within 0.14 cm, and it was found that the error limit of the large scale specified in the cadastral and aerial survey was satisfied. In addition, in order to increase the usability of smart city realization using a drone-based 3D urban digital twin model, the model built in this study was used to implement Prospect right analysis, landscape analysis, Right of light analysis, patrol route analysis, and fire suppression simulation training. Compared to the existing aerial photographic survey method, it was judged that the accuracy of the naked eye reading point is more accurate (about 10cm) than the existing aerial photographic survey, and it is possible to reduce the construction cost compared to the existing aerial photographic survey at a construction area of about 30㎢ or less.