• Analytical Science and Technology
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• v.32 no.3
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• pp.96-104
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• 2019

Agastache rugosa, known as Korean mint, is a medicinal plant with many beneficial health effects. In this study, a simple and reliable HPLC-UV method was proposed for the quantification of rosmarinic acid (RA) in the aqueous extracts of A. rugosa. RA was selected as a quantification marker due to its easiness in procurement and analysis. The developed method involved chromatographic separation on a $C_{18}$ column ($250{\times}4.6mm$, $5{\mu}m$) at room temperature. The mobile phase consisted of water and acetonitrile both containing 2 % acetic acid and was run at a flow rate of $1mL\;min^{-1}$. The method was validated for specificity, linearity, precision, and accuracy. It was specific to RA and linear in the range of $50-300{\mu}g\;mL^{-1}$ ($r^2=0.9994$). Intra-day, inter-day, and inter-analyst precisions were ${\leq}0.91%\;RSD$, ${\leq}1.40%\;RSD$, and 1.94 % RSD, respectively. Accuracy was 93.3-95.9 % (${\leq}1.21%\;RSD$). The method could be applied to three batches of bulk samples and three batches of lab scale samples, which were found to be $0.64({\pm}0.04)mg\;g^{-1}$ and $0.48({\pm}0.02)mg\;g^{-1}$ for the dried raw materials of A. rugosa. The results show that the proposed method can be used as a readily applicable method for QC of health functional foods containing the aqueous extracts of A. rugosa.

• Journal of the Korean Society of Marine Environment & Safety
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• v.16 no.3
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• pp.249-258
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• 2010

This study seeks to improve NFRDI Serial Oceanographic observation (NSO) system which has been operated at current observation stations in the Korean Seas since 1961 and suggests the direction of NSO for practical use of Korean operational oceanographic system. For improvement, data handling by human after CTD (Conductivity-Temperature-Depth) observation on the deck, data transmission, data reception in the land station, and file storage into database need to be automated. Software development to execute QA/QC (Quality Assurance/Quality Control) of real-time oceanographic observation data and to transmit the data with conversion to appropriate format automatically will help to accomplish the automation. Inmarsat satellite telecommunication systems with which have already been equipped on board the current observation vessels can realize the real-time transmission of the data. For the near real-time data transmission, CDMA (Code Division Multiple Access) wireless telecommunication can provide efficient transmission in coastal area. Real-time QA/QC procedure after CTD observation will help to prevent errors which can be derived from various causes.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.5
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• pp.262-268
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• 2015

This study established an analytical method to simultaneously determine six organophosphorous pesticides [methyldemetone-S, diazinon, fenitrothion, parathion, phentoate, and O-ethyl O-(4-nitrophenyl) phenylphosphonothioate (EPN)] and carbaryl in water using a gas chromatography/mass spectrometry (GC/MS) system coupled with on-line micro extraction by packed sorbent (MEPS) and programmed temperature vaporizer (PTV) injector. Polystyrene divinylbenzene (PDVB) was used as a sorbent of MEPS. The effects of elution solvents, pH, elution volume and draw-eject cycles of samples on sample pretreatment process were investigated. Also, quality assurance and quality control (QA/QC) and the recovery of the pesticides in environmental samples were evaluated. The elution was performed using $30{\mu}L$ of a mixed solvent (acetone : dichloromethane = 80 : 20 (v/v)). Sample pretreatment processes were optimized with seven cycles of draw-eject of sample (1 mL) spiking an internal standard and sulfuric acid. At lower pH, the analytical sensitivity of diazinon decreased, but that of carbaryl increased. The method detection limit and the limit of quantification for this method were 0.02~0.18 and $0.08{\sim}0.59{\mu}g/L$, respectively. The method precision and accuracy were 1.5~11.5% and 83.3~129.8%, respectively, at concentrations of $0.5{\sim}5.0{\mu}g/L$. The recovery rates for all the pesticides except carbaryl in various environmental samples ranged 75.7~129.3%. The recovery rate of carbaryl in effluent sample was over 200% whereas carbaryl in drinking water, groundwater, and river water were in the acceptable range.

• Korean Journal of Microbiology
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• v.44 no.1
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• pp.43-48
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• 2008

Standard sample for quality control of total coliform measurement was procured by addition of nalidixic acid and cephalexin as bacteriostatic agents to Escherichia coli cultured broth. After making the standard sample, the number of E. coli was measured by fluorescence microscopic count method and plate count method by 12 hr interval. The numbers of E. coli remained unchanged for at least for 48 hr at room temperature which ranged from 3.5 to $4.2{\times}10^5\;cells/ml$ and from 1.0 to $1.2{\times}10^4\;CFU/ml$ by direct fluorescence microscopic count method and plate count method, respectively. This result suggests that microbial standard sample with bacteriostatic agents of nalidixic acid and cephalexin is usable for quantitative quality control.

• Journal of radiological science and technology
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• v.46 no.1
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• pp.1-8
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• 2023

As the demand for bone mineral density testing increases in Korea, which is close to an aging society, it is necessary to evaluate the repeatability of equipment such as femur phantom other than l-spine for more accurate diagnosis. However, in clinical practice, it is often not possible to proceed such evaluation due to insufficient quality control conditions. Therefore, this study is to evaluate the usefulness of the femur phantom after fabricating the same using 3D printing technology. The femur phantom was output using GlowFill filament and FDM 3D printing type. Each phantom was repeatedly scaned 20 times to compare whether the existing l-spine phantom and the fabricated femur phantom were suitable as a phantom for quality control. Each time the seven researchers took three times, the location of the femur phantom was readjusted, and then scanned to confirm the error between the researchers. As a result of conducting repeatability evaluation using femur phantom, the coefficient of variation rate was 2%, which was within the minimum precision tolerance of 2.5%. The reproducibility between the researcher was also found to be suitable as the average coefficient of variation was 0.031 and the coefficient of variation rate was 3.1%, which was within the minimum precision error range of 5%. In conclusion, it is considered that the prospective attitude and usefulness of the femur phantom fabricated by 3D printing in clinical practice will be sufficient.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.9
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• pp.1337-1346
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• 2015

In this paper, pattern classifier is designed to classify precipitation and non-precipitation events from weather radar data. The proposed classifier is based on Fuzzy Neural Network(FNN) and consists of three FNNs which operate in parallel. In the proposed network, the connection weights of the consequent part of fuzzy rules are expressed as two polynomial types such as constant or linear polynomial function, and their coefficients are learned by using Least Square Estimation(LSE). In addition, parametric as well as structural factors of the proposed classifier are optimized through Differential Evolution(DE) algorithm. After event classification between precipitation and non-precipitation echo, non-precipitation event is to get rid of all echo, while precipitation event including non-precipitation echo is to get rid of non-precipitation echo by classifier that is also based on Fuzzy Neural Network. Weather radar data obtained from meteorological office is to analysis and discuss performance of the proposed event and echo patter classifier, result of echo pattern classifier compare to QC(Quality Control) data obtained from meteorological office.

• Journal of the Korean Society of Clothing and Textiles
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• v.27 no.3_4
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• pp.354-363
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• 2003

In this research, an internet-based fabric information system has been developed. Recently, the numbers of textile industries which have their own homepages to advertise their product fabrics fur apparel through the Internet and textile e-Commerce web sites rapidly increase. Unfortunately, traditional fabric information systems based on direct meeting and trust cannot give sufficient information to numerous visitors of the Internet sites including fabric buyers for apparel. They can just view 3-dimensional fabric images and text-based specifications such as fabric density, composition, colors, weight, etc. To solve these problems, the new fabric information system fur apparel has been developed. The web-based fabric information system is composed of the following six modules; $\circled1$ fabric database management system, $\circled2$ a 3-D fabric drape image viewer to illustrate fabric appearances, $\circled3$ a virtual wearing system to apply a fabric to garment designs, $\circled4$ a fabric property viewer to confirm fabric characteristics, $\circled5$ a QC (quality control) document generator to manufacture high qualify garments with a fabric, and$\circled6$actual display mall to view actual fabrics. The fabric information system is simply performed by visitors clicking the buttons hyper-linked with JAVA applets on web browser. The web-based fabric information system enables the web site visitors to understand fabrics shown on the Internet in more details.

• Archives of Pharmacal Research
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• v.24 no.6
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• pp.601-606
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• 2001

A simple assay method of recombinant human epidermal growth factor (rhEGF) in a pharmaceutical preparation was studied and validated by capillary electrophoresis (CE) using micellar electrokinetic chromatography (MEKC) techniques. Factors affecting the migration behavior and separation performances of the peptide; type of buffers pH, butler concentration, and concentration of sodium dodecyl sulfates (SDS) were investigated to optimize the analytical performance. CE was performed using running buffers 50.0 mM borate (pH 8.5) containing 12.5 mM SDS at 20 $mutextrm{V}$ of the applied voltage. Calibration curves for the rhEGF showed good linearity (r>0.999) over the wide dynamic range from 1.25 to $100{\mu\textrm{g}}/ml$. Sample analysis was performed by using standard addition method to eliminate the matrix effects of dosage vehicle. This method is assumed to be useful for quality control (QC) of various forms of pharmaceutical products of the peptide.

• Journal of Advanced Marine Engineering and Technology
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• v.17 no.5
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• pp.18-32
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• 1993

A marine engine system (MES) should be evaluated by not only reliability (R) but also maintainability (M) and manning index (MI), because this system can be recognised as a typical man-machine system. In 1977 at the first ICMES Conference in Paris one of the authors presented a total evaluation of the MES with the three indices, R, M, MI, proving the human ability of detecting faults and defects in this system. This paper describes how the MES has developed from the point of view of the above three indices during the past 30 years in Japan and its problems in the future, and arrives at the following conclusions : the reliability of the MES has developed due to quality control (QC) ; the maintainability of the MES has improved due to education and training ; the manning index of the MES has improved due to Rand M ; the availability of the MES has kept constant due to the decreasing complement onboard, at the rate of one person per year approximately ; and two esimations having the three indices were shown by the SRIC 1990 Data Base in Japan, for the two kinds of subsystems in the developed MES.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.446-446
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• 2022

본 연구에서는 MODIS(MODerate resolution Imaging Spectroradiometer) 다중 위성영상을 기반으로 전국 시공간 토양수분 및 토양수분 기반의 가뭄지수 SWDI(Soil Water Deficit Index)를 산정하였다. 시공간 토양수분의 산정을 위해 입력자료로 MODIS 위성의 지표면온도(Land Surface Temperature, LST), 증발산 및 식생(Enhanced Vegetation Index, EVI; Fraction of Photosynthetically Active Radiation, FPAR; Leaf Area Index, LAI; Normalized Difference Vegetation Index, NDVI) 관련 산출물 자료와 지상 관측자료인 일 단위 강수량 자료를 구축하였다. MODIS 위성영상은 산출물별로 제공되는 QC(Quality Control) 영상을 활용해 보정을 수행하였고, 공간 강수량 자료는 기상청에서 제공하는 전국 92개 지점의 종관기상관측자료를 구축하여 공간보간기법인 역거리가중법을 적용해 생성하였다. 실측 토양수분은 농촌진흥청에서 제공하는 76개 지점의 토양 깊이 10 cm에 설치된 TDR(Time Domain Reflectomerty) 센서에서 측정된 토양수분 자료를 활용하였으며, 토양수분 모의 시 토양 속성을 고려하기 위해 국립농업과학원에서 제공하는 토양도를 구축하여 활용하였다. 토양수분 산정 모형은 다중선형회귀모형(Multiple Linear Regression Model, MLRM)을 활용하였으며, 계절 및 토성에 따른 회귀식을 산정하였다. 회귀식 기반의 토양수분과 토성별 포장용수량 및 영구위조점 값을 이용하여 SWDI를 산정하고, 실제 가뭄 발생 시기 및 지역과의 비교하고자 한다.