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Antibacterial and Antibiofilm Activities of Leaf Extracts of Stewartia koreana against Porphyromonas gingivalis (Porphyromonas gingivalis에 대한 노각나무 잎 추출물의 항균활성 및 생물막 형성 억제 효과)

  • Kim, Hye Soo;Park, Min Jeong;Kim, Soo Jeong;Kim, Bu Kyung;Park, JunHo;Kim, DaeHyun;Cho, Soo Jeong
    • Journal of Life Science
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    • v.31 no.3
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    • pp.330-337
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    • 2021
  • This study was conducted to investigate the potential of Stewartia koreana as oral healthcare materials. The antibacterial activity of ethanol extracts from leaves and branches of S. koreana against oral bacteria was confirmed. The leaf and branch extracts (1 mg/disc) showed antibacterial activity against P. gingivalis only among several tested oral bacteria. The leaf extracts showed higher antibacterial activity, with values similar to those of chlorhexidine, which was used as a positive control. The MIC of the leaf extract against P. gingivalis was 0.4 mg/ml and showed bacteriostatic action. The inhibitory effects of the extract on biofilm formation and on gene expression related to biofilm formation by P. gingivalis were determined by biofilm biomass staining, scanning electron microscopy (SEM), and qRT-PCR analysis. The biofilm production rate and cell growth of P. gingivalis in the cultures treated with 0.2-2.0 mg/ml of S. koreana leaf extracts were significantly decreased in a concentration-dependent manner. The inhibitory effect on the formation of P. gingivalis biofilms at concentrations of 1 mg/ml was confirmed by SEM. The qRT-PCR analysis showed concentration-dependent suppression of the fimA and fimB gene expression associated with fimbriae formation in the cultures treated with 0.2-2.0 mg/ml S. koreana leaf extract. These results support the conclusion that S. koreana leaf extracts can be used as oral healthcare materials derived from natural materials, as demonstrated by the antibacterial action and inhibition of biofilm formation of P. gingivalis.

The Analysis of Suspended Sediment Load of Donghyang and Cheoncheon Basin using GIS-based SWAT Model (GIS 기반 SWAT 모델을 이용한 동향·천천유역의 부유사량 분석)

  • Lee, Geun-Sang;Kim, Yu-Ri;Ye, Lyeong;Lee, Eul-Rae
    • Journal of the Korean Association of Geographic Information Studies
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    • v.12 no.2
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    • pp.82-98
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    • 2009
  • This study applied SWAT model to analyze suspended sediment load that is influence on the high density turbid water in Donghyang and Cheoncheon basin, which are located in the upstream of Yongdam Dam. GIS data such as DEM, land cover map and soil map, and meteorological data were used as the input data of SWAT model. And the rating curve equation and Q-SS equation of Donghyang and Cheoncheon gauge station were applied as the measured values of them. As the result of flowout, the coefficient of determination ($R^2$) and the Nash-Sutcliffe coefficient of efficiency (EI) of model calibration showed high as 0.87 and 0.87 at Donghyang gauge station, and the $R^2$ and EI of model validation were high as 0.95 at Cheoncheon gauge station. Also, as the result of suspended sediment load, the $R^2$ and EI of model calibration were high as 0.77 and 0.76 at Donghyang gauge station, and the $R^2$ and EI of model validation marked high as 0.867 and 0.80 at Cheoncheon gauge station. It is considered that the suspended sediment load of 2003 showed the highest due to rainfall amounts and rainfall intensity in using SWAT model. The results of suspended sediment modeled in this study can be applied to the decision-making support data for the evaluation of soil erosion possibility and turbid water potential in the management of reservoir.

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A Survey on Nurses' Utilization of Computerization in Nursing Practice (간호사의 간호업무 전산화 활용에 대한 조사연구)

  • Rhee, In-Soon
    • Journal of Korean Academy of Nursing Administration
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    • v.5 no.2
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    • pp.209-224
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    • 1999
  • I have practiced this reserch for the purpose of proposition of basic data for amendment and addition of computer system after I surveyed the degree of abilities and satisfaction on the computerization in nursing\ practice. Subjects were collected from September 1 to September 30, 1998. Study subjects are 151 clinical nurses who are working at university hospital in Chonbuk area. Study instrument consists of 116 questionnaire which was developed by Kim H. K(1998). The data were analized number, mean ,t-test, ANOVA by using SPSS. The study results are as follows: 1. Most of the nurses who answered the questions were educated computerizing(96%). The abilities of computer program utilities were the most in inputting data(74%). The program nurses wanted computerizing education was wordprocess, dealing internet and statistics. 2. As for applying parts of computer system in nursing, the most nurses were Dr's order check (96%), treatment activity(91.4%), medication(89.4%), lab. test(87 .4%), transfering department(85.4%), transfering room(79.5%), diet(71.8%), discharge (70.2%), Barcord Sticker(70.2%) , reservation(62.2%) in order that were all conected order system mutually to other part. It showed that computer system was not applied for treating the original nursing work such as nursing record (13%), duty scheduling(6.0%) , nursing process(4.6%) , Q.I(1.3%), nursing research(1.3%), education(1.3%), 3. As for the benefit when computer system is applied for, the most respondence was promptness of work and convenience(90.6%) , exactness of work (82.8%), offering information exactily and efficiently(36.3%), offering good quality of nursing (6.0%) in order. 4. The degree of contentment on computerizing in nursing practice showed average 3.24%. The best marking item is that they are eager to participate in the computer education. Next, the automatic output of label and giving the number automatically is to prevent loss and mentioned items of patient registration from being changed(3.95) and to prevent mistakes possibly happening because of doctor's difficult order(3.85). 5. The problems which may happen to in nurses' utilization of computerization for the nursing practice showed average 3.18. The most problem is that the practice may stop because of the problem of computer itself(3.67), and the next, the indication of act can be imperfect(3.66) , manual training may overlap because of incomplete computerization (3.60), practical education for the computerizing is lack(3.41), and the computer literate nurses are lack(3.40) . 6. Study subject's contentment by age was significant difference(F=3.10,P=0.0119). Study subject's contentment by job posision was significant difference(F=6.001P=0.0034) I will propose the following according to the above results. The domain of original nursing practice is urgernt. Manual and indication of act should be made before long in computer obstacle. Nursing department should support the nurses so that they could receive the education needed for the nurses themselves.

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Simultaneous Transfer and Patterning of CVD-Grown Graphene with No Polymeric Residues by Using a Metal Etch Mask

  • Jang, Mi;Jeong, Jin-Hyeok;Trung, T.Q.;Lee, Nae-Eung
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.642-642
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    • 2013
  • Graphene, two dimensional single layer of carbon atoms, has tremendous attention due to its superior property such as high electron mobility, high thermal conductivity and optical transparency. Especially, chemical vapor deposition (CVD) grown graphene has been used as a promising material for high quality and large-scale graphene film. Unfortunately, although CVD-grown graphene has strong advantages, application of the CVD-grown graphene is limited due to ineffective transfer process that delivers the graphene onto a desired substrate by using polymer support layer such as PMMA(polymethyl methacrylate). The transferred CVD-grown graphene has serious drawback due to remaining polymeric residues generated during transfer process, which induces the poor physical and electrical characteristics by a p-doping effect and impurity scattering. To solve such issue incurred during polymer transfer process of CVD-grown graphene, various approaches including thermal annealing, chemical cleaning, mechanical cleaning have been tried but were not successful in getting rid of polymeric residues. On the other hand, lithographical patterning of graphene is an essential step in any form of microelectronic processing and most of conventional lithographic techniques employ photoresist for the definition of graphene patterns on substrates. But, application of photoresist is undesirable because of the presence of residual polymers that contaminate the graphene surface consistent with the effects generated during transfer process. Therefore, in order to fully utilize the excellent properties of CVD-grown graphene, new approach of transfer and patterning techniques which can avoid polymeric residue problem needs to be developed. In this work, we carried out transfer and patterning process simultaneously with no polymeric residue by using a metal etch mask. The patterned thin gold layer was deposited on CVD-grown graphene instead of photoresists in order to make much cleaner and smoother surface and then transferred onto a desired substrate with PMMA, which does not directly contact with graphene surface. We compare the surface properties and patterning morphology of graphene by scanning electron microscopy (SEM), atomic force microscopy(AFM) and Raman spectroscopy. Comparison with the effect of residual polymer and metal on performance of graphene FET will be discussed.

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Realities of a Hospital's web-site' Management and It's Effect on Hospital Management (병원의 홈페이지 관리운영 실태와 병원경영에 미치는 효과)

  • Hwang, Byung-Deog;Im, Bock-Hee;Lee, Young-Hwan
    • The Journal of the Korea Contents Association
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    • v.10 no.3
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    • pp.241-249
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    • 2010
  • The purpose of this study is to provide basic information for marketing strategy for hospitals in Busan Metropolitan area by investigating of the web-site management and effect on hospital management about the web-sites managers. Survey of 53 web-site managers was taken between May 1st and May 25th 2008. The survey was carried out to gather information about characteristics of web-site managers and creating, managing and operating process of web-sites and web-sites' effect and information sharing abilities. The results of survey are as follows. First, most of hospitals' web-sites were launched between 2001 to 2005 via outsourcing. Most of hospitals spent about one to three million won for their web-sites and renew web-sites every year. Most of these web-sites have hospital PR, Q&A, and on-line support functions. Second, most of whom participated in survey have agreed that a hospital web-site has influence in hospital management in various categories such as introducing hospital to medical examination, making doctor's appointment, providing patient guidance, providing medical information, and patient counselling. This study shows that effects of web-sites are closely related to web-site satisfaction level. Therefore, to raise the hospital satisfaction level, it is necessary for hospitals to put more efforts in creating web-site that provides more medical information and improved on-line services.

The effect of exercise on cognitive function in the elderly : A systematic review and meta-analysis (운동이 노인의 인지기능에 미치는 영향 : 체계적 문헌고찰 및 메타분석)

  • Chung, Bok Yae;Han, Ji Young
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.5
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    • pp.1375-1387
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    • 2016
  • The purpose of this study was to evaluate the effect of exercise on cognitive function in the elderly through a systematic literature review and meta-analysis. For the study purpose, 14 studies were selected through a systematic process of using several databases and 11 studies were used to estimate the effect size of exercise on cognitive function. Meta-analysis was performed using a random effects model, and the effect size on cognitive function was calculated. The effect size for cognitive function of exercise intervention was Hedges' g=1.05 (95% CI: 0.61~1.50), indicating a large effect size. For heterogeneity, moderator analysis was performed using intervention, number of times per week, intervention duration, and cognitive function measurement. Cognitive function measurement was statistically significant, the other moderators did not significant difference. Results support that exercise has significant positive effects on cognitive function in elderly in korea. It also provided a basis that can be applied to exercise intervention design for cognitive function.

Factors Predicting the Interface Pressure Related to Pressure Injury in Intensive Care Unit Patients (중환자실 환자의 욕창 관련 경계압력 예측요인)

  • Shine, Ji Seon;Kim, Soo Jin;Lee, Ji Hyun;Yu, Mi
    • Journal of Korean Academy of Nursing
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    • v.47 no.6
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    • pp.794-805
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    • 2017
  • Purpose: Interface pressure is a factor that contributes to the occurrence of pressure injuries. This study aimed to investigate interface pressure at common sites of pressure injury (occipital, gluteal and peritrochanteric areas), to explore the relationships among risk factors, skin condition and interface pressure, and to identify risk factors influencing interface pressure. Methods: A total of 100 patients admitted to the intensive care unit were enrolled at a tertiary teaching hospital in Korea. Interface pressure was recorded by a scanning aid device (PalmQ). Patient data regarding age, pulmonary disease, Braden Scale score, body mass index, serum albumin, hemoglobin, mean blood pressure, body temperature, and oxygen saturation were included as risk factors. Data collected from July to September 2016 were analyzed using binary logistic regression. Results: The mean interface pressure of the occipital, gluteal, and right and left peritrochanteric areas were 37.96 (${\pm}14.90$), 41.15 (${\pm}16.04$), 53.44(${\pm}24.67$), and 54.33 (${\pm}22.80$) mmHg, respectively. Predictive factors for pressure injuries in the occipital area were age ${\geq}70$ years (OR 3.45, 95% confidence interval [CI]: 1.19~9.98), serum albumin deficit (OR 2.88, 95% CI: 1.00~8.26) and body temperature ${\geq}36.5^{\circ}C$ (OR 3.12, 95% CI: 1.17~8.17); age ${\geq}70$ years (OR 2.81, 95% CI: 1.10~7.15) in the right peritrochanteric area; and body temperature ${\geq}36.5^{\circ}C$ (OR 2.86, 95% CI: 1.17~6.98) in the left peritrochanteric area. Conclusion: Our findings suggest that old age, hypoalbuminemia, and high body temperature may be contributory factors to increasing interface pressure; therefore, careful assessment and nursing care of these patients are needed to prevent pressure injury. Further studies are needed to establish cutoff values of interface pressure for patients with pressure ulcers.

Reexamination of Coach-Athlete Relationship Maintenance Scale in Pro Baseball (프로야구 코치-선수관계 유지 척도 재검증)

  • Huh, Jin-Young;Choi, Hun-Hyuk
    • 한국체육학회지인문사회과학편
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    • v.55 no.1
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    • pp.221-233
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    • 2016
  • The purpose of this study was to prove a development and initial validation of the korean version of coach-athlete relationship maintenance scale that originated from the work of Rhind & Jowett(2012) in pro baseball. The items were then administered to 132 Participants(29 coaches and 103 athletes) completed the questionnaires of the coach-athlete relationship maintenance in First preliminary investigation. Maximum likelihood estimate was used to identify the latent underlying structure. In order to verify the validity of Korean version of coach-athlete relationship maintenance was administered to an independent sample of 273 coaches and athletes. Pro baseball coach-athlete relationship maintenance is consisted of six factors(25 items) with conflict management, motivational, preventative, openness/assurance, support, and social network. SPSS18.0 and AMOS16.0 were used to analyze the exploratory factor analysis, confirmatory factory analysis and internal consistency, test-retest with bootstrapping using of the data in this study. The results of the pro baseball coach-athlete relationship maintenance scale had six factors with 25 items, and each six factor was positively correlated. Overall, this study verified pro baseball coach-athlete relationship maintenance questionnaire. Thus, suggest that path of comparing the differences between the first division and farm team by using the test of the structural model invariance across the groups.

Investigation of thermal hydraulic behavior of the High Temperature Test Facility's lower plenum via large eddy simulation

  • Hyeongi Moon ;Sujong Yoon;Mauricio Tano-Retamale ;Aaron Epiney ;Minseop Song;Jae-Ho Jeong
    • Nuclear Engineering and Technology
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    • v.55 no.10
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    • pp.3874-3897
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    • 2023
  • A high-fidelity computational fluid dynamics (CFD) analysis was performed using the Large Eddy Simulation (LES) model for the lower plenum of the High-Temperature Test Facility (HTTF), a ¼ scale test facility of the modular high temperature gas-cooled reactor (MHTGR) managed by Oregon State University. In most next-generation nuclear reactors, thermal stress due to thermal striping is one of the risks to be curiously considered. This is also true for HTGRs, especially since the exhaust helium gas temperature is high. In order to evaluate these risks and performance, organizations in the United States led by the OECD NEA are conducting a thermal hydraulic code benchmark for HTGR, and the test facility used for this benchmark is HTTF. HTTF can perform experiments in both normal and accident situations and provide high-quality experimental data. However, it is difficult to provide sufficient data for benchmarking through experiments, and there is a problem with the reliability of CFD analysis results based on Reynolds-averaged Navier-Stokes to analyze thermal hydraulic behavior without verification. To solve this problem, high-fidelity 3-D CFD analysis was performed using the LES model for HTTF. It was also verified that the LES model can properly simulate this jet mixing phenomenon via a unit cell test that provides experimental information. As a result of CFD analysis, the lower the dependency of the sub-grid scale model, the closer to the actual analysis result. In the case of unit cell test CFD analysis and HTTF CFD analysis, the volume-averaged sub-grid scale model dependency was calculated to be 13.0% and 9.16%, respectively. As a result of HTTF analysis, quantitative data of the fluid inside the HTTF lower plenum was provided in this paper. As a result of qualitative analysis, the temperature was highest at the center of the lower plenum, while the temperature fluctuation was highest near the edge of the lower plenum wall. The power spectral density of temperature was analyzed via fast Fourier transform (FFT) for specific points on the center and side of the lower plenum. FFT results did not reveal specific frequency-dominant temperature fluctuations in the center part. It was confirmed that the temperature power spectral density (PSD) at the top increased from the center to the wake. The vortex was visualized using the well-known scalar Q-criterion, and as a result, the closer to the outlet duct, the greater the influence of the mainstream, so that the inflow jet vortex was dissipated and mixed at the top of the lower plenum. Additionally, FFT analysis was performed on the support structure near the corner of the lower plenum with large temperature fluctuations, and as a result, it was confirmed that the temperature fluctuation of the flow did not have a significant effect near the corner wall. In addition, the vortices generated from the lower plenum to the outlet duct were identified in this paper. It is considered that the quantitative and qualitative results presented in this paper will serve as reference data for the benchmark.

Characteristics of Vegetation Structure of Managed Area by Oak Wilt Disease in Bukhansan National Park (북한산국립공원 참나무시들음병 방제지역 식생구조 특성 연구)

  • Han, Bong-Ho;Choi, Jin-Woo;Yeum, Jung-Hun;Lee, Kyong-Jae
    • Korean Journal of Environment and Ecology
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    • v.28 no.3
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    • pp.342-356
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    • 2014
  • This study aims to provide the fundamental data for restoration through the analysis of vegetation structure characteristic for managed area with deforest and fumigation among the places damaged by oak wilt disease in Bukhansan National Park. Study areas were selected in six damaged areas with 18 plots ($20m{\times}20m$) including comparing plots between year 2006 and year 2011 after preliminary study finding the exact location with easy access. Analysis items are density and coverage of under story layer, Importance Percentage of under story layer and Importance Percentage of urban adapted species and alien species. As a result, density and coverage under the canopy layer's vegetation was higher than comparing plot in Musugol valley and Soquicheon valley which 4 years and more passed. And Wondobong, Darakwon, Doseonsa and Dobong valley which had not been passed 3 years after deforestation and fumigation decreased in those of vegetation. However, the plots in Wondobong and Doseonsa was analyzed to be higher in density of shrubs than comparing plot. In terms of distirbution of species in under canopy layer which is grown as a upper vegetation, Quercus serrata and Sorbus alnifolia dominated each other in under canopy layer except for Wondobong and Darakwon. Wondobong continuously maintained Quercus mongolica and Q. mongolica and Pinus densiflora dominated in under canopy layer of Darakwon. S. alnifolia which is Urban adapted species were distributed in most study areas. In terms of alien species, Magnolia obovata and Robinia pseudoacacia were newly intruded in the opened crown, and Pueraria thunbergiana was distributed in Soquicheon valley. As the result of soil analysis, acidification(pH 4.49) and low level of organic matter(3.23%), available phosphate(1.40mg/kg) and exchangeable cation were analyzed and it was considered that those environment poorly support the vegetation growth.