• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.166-175
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• 2005

Objecitve: To present criteria for acupuncture standardization, which will improve the quality of acupuncture and secure safety, through studies of the biocompatibility of acupuncture needles. Methods: Acupuncture needles distributed in Korea were studied. Acute poisonous tests and pyrogenicity materials tests were executed to study the biocompatibility of acupuncture needles. Results & Conclusions: All 3 brands of acupuncture needles commonly distributed in Korea were found suitable for medical use, through acute poisonous tests and pyrogenicity materials tests. However, the medical instrument standards of the Korea Food and Drug Administration for acupuncture lack criteria concerning acute poisonous tests and pyrogenicity materials tests. The criteria for these tests should be standardized in order to secure the biocompatibility of acupuncture needles.

• The Korean Journal of Nuclear Medicine
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• v.32 no.5
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• pp.425-432
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• 1998

Purpose: For the purpose of using Re-188 as a therapeutic radionuclide, we performed the quality control of the W-188/Re-188 generator system. Materials and Methods: Several quality control tests of the Re-188 eluate from generator were carried out for about 300 days. After elution of Re-188 with normal saline (20 ml), chromatogram and gamma-ray spectrum of Re-188 eluate were obtained. The presence of aluminum which was derived from the alumina bed of the generator was detected by using aluminum ion indicator kit. Re-188 eluate was allowed to decay for several days, and then W-188 breakthrough in the Re-188 eluate was measured by detecting gamma-ray at 227 keY and 290 keV. The pH and the pyrogenicity of the eluate were checked. The Re-188 bolus was concentrated with ion exchange columns. Results: The radioactivity of Re-188 eluate from the generator was $67.4{\pm}7.0%$ of W-188 during 270 days, and it was highest at third day after previous elution. Radiochemical purity of Re-188 eluate obtained from chromatogram was higher than 99%. Gamma-ray spectrum of Re-188 eluate showed a peak at 155 keV. Aluminum ion and W-188 contamination were not detected. The PH of Re-188 eluate was 3 and the concentration yield was 85%. Conclusion: Our experiments and results on quality control tests of Re-188 eluate from W-188/Re-188 generator may be useful for setting W-188/Re-188 generator in hospitals.