• Parasites, Hosts and Diseases
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• v.43 no.1 s.133
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• pp.15-18
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• 2005

The diagnosis of human hydatidosis is primarily made using radiological and serological methods. Radiological methods are generally of low specificity and serological methods lack sensitivity, especially for pulmonary disease. In this study the capabilities of a new rapid test, the hydatid antigen dot immunobinding assay (HA-DIA), which was developed for the diagnosis of pulmonary hydatidosis, were studied and compared with another immunodiagnostic method, indirect hemagglutination (IHA). The study subjects included 18 patients, 9 women, 9 men; range 7 to 63 years; mean 30 years, with surgically proven pulmonary hydatidosis, a control group comprised of 14 patients; viral respiratory infections (1), cirrhosis (2), connective tissue disease (2), taeniasis (3), and 6 healthy donors. We found that the HA-DIA test had a sensitivity of $67\%$ and specificity of $100\%$, and that the IHA test had a sensitivity of $50\%$ and specificity of $100\%$. We conclude that HA-DIA is a simple, rapid, low cost assay that does not require instrumentation and has a higher sensitivity than IHA for the diagnosis of pulmonary hydatidosis.

• Korean Journal of Veterinary Service
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• v.26 no.1
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• pp.81-88
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• 2003

A cross-sectional epidemiological study using a multistage sampling strategy in slaughter cattle in Mymensingh, Bangladesh was conducted during September 2001 to April 2002 to study distributions and risk factors of specific pulmonary lesions and diseases. The pulmonary lesions and diseases were diagnosed on the basis of macroscopic and microscopic pathological and parasitological findings. The frequency distribution of pulmonary lesions and diseases in slaughter cattle was found to vary among categories of the study variables. The risk factors identified on statistical basis were male cattle and ${\leq}3$ years old cattle and summer in congestion, slightly thin physical condition and summer season in pulmonary emphysema, slightly thin physical condition in parasitic bronchitis as well as female cattle, autumn and rainy seasons in pulmonary hydatidosis. The population impact and etiologic significance of summer season on pulmonary congestion and emphysema was more important than that of adult male cattle. The population impact and etiologic significance of autumn season on pulmonary hydatidosis was more important than that of female cattle during rainy season. Population impact of slightly thin cattle on parasitic bronchitis was poor.

• Journal of Chest Surgery
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• v.22 no.3
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• pp.483-493
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• 1989

Echinococcal or hydatid cyst is one of the most important zoonoses and commonly seen throughout the world, especially sheep and cattle raising areas, but rare in Korea. The causative organism, Echinococcus granulosus, is a small tapeworm and dogs are the usual source of infestation. Lung is the second most common focus for this disease, after liver. Recently, with increasing numbers of Koreans visiting to those endemic countries especially Middle East, the reports of hydatidosis are increasing. Authors experienced two cases of pulmonary hydatid cyst in the 31 year old male and 44 year old male who had a history of spending 2 * 3 years in Middle East. we found them in incidental routine chest X-ray.

• Journal of Chest Surgery
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• v.53 no.6
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• pp.387-391
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• 2020

Background: Hydatidosis is a major health problem around the world, especially in the Mediterranean region. Cysts can break open or develop secondary bacterial infections, altering the clinical presentation. Methods: Patients who underwent hydatid cyst surgery at Al-Mouassat University Hospital in Damascus, Syria between January 2006 and December 2017 were evaluated. Cases involving isolated hepatic cysts were excluded. The patients were divided into those with perforated hydatid cysts (group 1) and those with intact hydatid cysts (group 2). Results: This study included 224 cases: 113 in group 1 (50.4%) and 111 in group 2 (49.6%). The median chest tube duration, hospitalization time, and postoperative complication rate were higher in group 1 than in group 2 (p=0.003, p=0.002, and p=0.006, respectively). In both groups, the most common symptom was cough (present in 178 patients in total [79.5%]), while chest pain (121 patients [54%]) and dyspnea (113 patients [50.4%]) were also common. Cough, hemoptysis, fever, and expectoration of cystic contents were significantly more frequent in group 1 than in group 2 (p<0.001). Conclusion: The early discovery and treatment of intact pulmonary hydatid cysts reduced the hospitalization time, chest tube duration, and postoperative complication rate. Relative to intact cysts, perforated cysts are more complex and are associated with more expensive and time-consuming surgical treatment.

• Parasites, Hosts and Diseases
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• v.47 no.4
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• pp.427-429
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• 2009

To establish a definite diagnosis for pulmonary hydatid disease, combination of radiology and serology is useful. In this study, 19 preoperative sera from patients with surgically confirmed pulmonary hydatidosis, 40 sera from patients with other parasitosis and pulmonary diseases, and 20 sera from healthy donors were evaluated using 4 different serological tests, i.e., the commercial ELISA (ELISA-kit) test, the ELISA (ELISA-lab) test prepared in our laboratory, the commercial indirect hemagglutination assay kit (IHA-kit) test, and the IHA test using sensitized sheep red blood cells with tannic acid (IHA-TA). The ELISA-kit was the most sensitive (84.2%) and the most specific test (100.0%). The ELISA-kit also demonstrated the highest positive (100.0%) and negative (95.2%) predictive values. The sensitivity of the ELISA-lab test, that we prepared, was found to be 73.6%, whereas the IHA-kit test and the IHA-TA test were found to be 73.6% and 68.4%, respectively. The specificity of these tests was 96.6%, 98.3%, and 83.3%, respectively. When all 4 tests were assessed together, it was found that the sensitivity had risen to 94.7%. When the ELISA-kit was assessed with the IHA-kit and IHA-TA together, it was found that the sensitivity was 89.5% and 84.2%, respectively. Likewise, the combination of the ELISA-lab and IHA-kit or IHA-TA allowed us to achieve a sensitivity of 84.2% in cases of pulmonary echinococcosis. In conclusion, the diagnosis would be imminent if least 2 tests were applied together.

• Parasites, Hosts and Diseases
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• v.55 no.4
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• pp.429-431
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• 2017

Hydatid cyst is usually located in the liver and lungs, rare cases showing localization in other organs or tissues. In the unusual location, echinococcosis is an excluding diagnosis that is established only after microscopic evaluation. Our first case occurred in a 67-year-old female previously diagnosed with pulmonary tuberculosis and hospitalized with persistent pain in the hip joint. The clinical diagnosis was tuberculosis of the joint, but the presence of the specific acellular membrane indicated a hydatid cyst of the synovial membrane, without bone involvement. Fewer than 25 cases of joint hydatidosis have been reported in literature to date. In the second case, the intramural hydatid cyst was incidentally discovered at autopsy, in the left heart ventricle of a 52-year-old male hospitalized for a fatal brain hemorrhage, as a result of rupture of an anterior communicating artery aneurysm. The conclusion of our paper is that echinococcosis should be taken into account for the differential diagnosis of cystic lesions, independently from their location.