• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2013년도 추계학술대회 초록집
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• pp.178-179
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• 2013

본 연구에서는 현재 사용되고 있는 건축물 내의 화장실 칸막이 재료를 대상으로 ISO 5660-1 콘칼로리미터(Cone calorimeter) 실험을 실시하여 대상 실험 재료들의 연소 특성을 비교 평가 하였다. 모두 5종류의 실험체를 사용하였으며, 화재 발생시 연소 중요 평가항목인 착화시간(Time to ignition), 총 방출열량(Total heat release), 최고 열방출율(Peak heat release rate), 평균 열방출율(Mean heat release rate)을 중점적으로 평가하였다. 실험결과, 착화시간은 일반 합판패널에서 빠르게 일어났으며, 총 방출열량, 최고 열방출율, 평균 열방출율은 고밀도 압축패널에서 높게 나타난 것으로 분석되었다.

• 정보화정책
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• 제24권3호
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• pp.27-41
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• 2017

최근 4차 산업혁명과 빅데이터의 중요성이 대두됨과 함께 공공 빅데이터 활용을 활성화기 위한 다양한 정책들이 마련되고 있으며, 이를 활용한 다양한 부가가치 창출이 활발히 이루어지고 있다. 하지만 공공 데이터 공개 의무 확대와 법제도 개선에도 불구하고 실질적으로 공공 빅데이터를 활용하기에는 아직 한계가 있다. 문헌연구에 따르면, 공공 빅데이터 개방을 위해 정부가 정책적으로 나아갈 방향에 대해 제시한 연구는 있지만, 실제 공공 빅데이터를 활용하는 사람들의 입장까지 고려한 연구는 부족한 실정이다. 따라서 본 연구는 국내 공공 데이터 개방 생태계에 대해 파악하고, 공공 빅데이터 개방의 주체인 제공자 입장(정부, 공공기관)과 사용자 입장(기업, 민간)에 대한 인터뷰를 통해 공공 빅데이터 개방 및 활용 활성화의 촉진요인과 저해요인을 도출하고, 각 요인 간의 인과관계분석을 통해 이슈를 도출하여 해결방안을 제시한다. 본 연구는 공공 빅데이터 개방 및 활용활성화 방안에 대해 두 가지 측면에서 함께 고려한 연구라는 점에서 학술적 시사점을 가지며, 도출된 이슈와 대안은 국내 공공 빅데이터 개방 및 활용 활성화를 도모하는 이해당사자에게 실무적 시사점을 줄 것으로 기대한다.

• 한국수자원학회논문집
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• 제45권6호
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• pp.597-606
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• 2012

DEM(Digital Elevation Model) 크기의 변화에 따라 특정 지역에 많은 규격의 수문 데이터가 존재할 수 있기 때문에, 어느 지역, 어느 기상 데이터에도 작동할 수 있는 수문 모형의 개발이 절실히 필요하게 되었다. 이와 같은 필요성을 설명하기 위해서 객체지향(object-oriented)적인 프로그래밍 기술을 적용한 GHISMO(Geographic and Hydrologic Information System Modeling Objects)라는 수문모형(hydrologic model)을 개발하였다. GHISMO의 가장 핵심적인 수문학적 접근방법은 저류-배출(storage-release)과 지표면 유효 강수량을 구하기 위하여 SCS curve number 방법을 사용한 것이다. 이 연구에서 수문모형의 모의실험 결과를 제공할 것이다.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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• pp.22-40
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• 2001

Apoptosis is characterized by DNA fragmentation, chromatin condensation and plasma membrane blebbing. These apoptotic processes have been mainly associated with genetic mechanisms. Recently, these processes have been also associated with mitochondrial events that include the release of cytochrome c and Diablo/SMAC by modulation of mitochondrial membrane permeability.(omitted)

• Asian Journal for Public Opinion Research
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• 제8권3호
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• pp.222-245
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• 2020

In the pandemic crisis, many governments implemented harsh interventions that might contradict democratic values and civil liberties. In Taiwan, the debate over whether or not to reveal personal information of infected persons to limit the coronavirus's spread poses the democratic dilemma between public health and civil liberties. This study examines whether and explains how Taiwan's people respond to the choice between individual privacy and collective security. We used survey data gathered in May 2020 to show that, first, the democratic values did not deter the pursuit of collective safety at the cost of civil liberty; rather, people with higher social trust were more likely to give up their civil liberties in exchange for public safety. Second, people who support democratic values and pursue collective security tend to avoid violating privacy by opposing the release of personal information. This study proves that democratic values do not necessarily threaten collective safety and that the pursuit of common good can co-exist with personal privacy.

• Nuclear Engineering and Technology
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• 제52권6호
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• pp.1231-1242
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• 2020

The Kori Unit 1 will be decommissioned after a permanent shutdown in June 2017. South Korea has a 0.1 mSv/yr exposure limit standard for limited or unlimited site release. This is South Korea's first commercial NPP; therefore, if the containment building is reused as a memorial hall, it will contribute to the improvement of public understanding and enhance the public's acceptance of NPPs. Also, existing Kori Unit 1 nuclear power plant manpower resources can be reused after decommissioning and resident staff and memorial hall visitors can activate nearby commercial areas. Therefore, such a reuse scenario may also prevent an economic recession. The exposure dose was calculated using the following scenarios: worker in the containment building, visitor in the containment building, and worker in buildings other than the containment building. The exposure dose in the buildings was calculated by the RESRAD-BUILD developed by the Argonne National Laboratory (ANL). The preliminary exposure dose and derived concentration guideline level (DCGL) were derived.

• The Journal of Asian Finance, Economics and Business
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• 제7권4호
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• pp.275-286
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• 2020

The study explores factors that affect the performance of responsibility accounting at public universities in Vietnam. The study conducted a survey of 130, out of 154 public universities in Vietnam and uses regression analysis methods. The results identify eight groups of factors affecting the performance of responsibility accounting at these establishments of higher education: Division of the organization into responsibility centers, Estimation and Reality, Cost and income allocation, University autonomy, Management decentralization, Estimation, Reward, and Report. Costs and income allocation for responsibility centers, university autonomy, and the division of universities into responsibility centers are shown to significantly affect the performance of public universities in Vietnam. The results show that the performance of responsibility accounting at public universities in Vietnam is influenced by decentralization of management, division of the organization into responsibility centers, reward, cost and income allocation, estimation, evaluation of the results achieved between the estimation compared with reality, release of reports and university autonomy. Among the factors, cost and income allocation, university autonomy, division of the organization into responsibility centers, reward and evaluation of results achieved between estimation and reality have strong impacts. The study findings also indicate that the school council does not affect responsibility accounting at these universities.

• Journal of Preventive Medicine and Public Health
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• 제39권3호
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• pp.199-204
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• 2006

Objectives: Mercury is a hazardous organ-specific environmental contaminant. It exists in a wide variety of physical and chemical states, each of which has unique characteristics for the target organ specificity. Exposure to mercury vapor and to organic mercury compounds specifically affects the CNS, while the kidney is the target organ for inorganic Hg compounds. Methods: In this study, mercury chloride $(HgCl_2)$ was studied in a renal derived cell system, i.e., the tubular epithelial Madin-Darby canine kidney (MDCK) cell line, which has specific sensitivity to the toxic effect of mercury. MDCK cells were cultured for 6-24 hr in vitro in various concentrations (0.1-100 M) of $HgCl_2$, and the markers of apoptosis or cell death were assayed, including DNA fragmentation, caspase-3 activity andwestern blotting of cytochrome c. The influence of the metal on cell proliferation and viability were evaluated by the conventional MTT test. Results: The cell viability was decreased in a time and concentration dependent fashion: decreases were noted at 6, 12 and 24 hr after $HgCl_2$, exposure. The increases of DNA fragmentation were also observed in the concentrations from 0.1 to 10 M of $HgCl_2$ at 6 hr after exposure. However, we could not observe DNA fragmentation in the concentrations more than 25 M because the cells rapidly proceeded to necrotic cell death. The activation of caspase-3 was also observed at 6 hr exposure in the $HgCl_2$ concentrations from 0.1 to 10 M. The release of cytochrome c from the mitochondria into the cytosol, which is an initiator of the activation of the caspase cascade, was also observed in the $HgCl_2-treated$ MDCK cells. Conclusions: These results suggest that the activation of caspase-3 was involved in $HgCl_2-induced$ apoptosis. The release of cytochrome c from the mitochondria into the cytosol was also observed in the $HgCl_2-treated$ MDCK cells. These findings indicate that in MDCK cells, $HgCl_2$ is a potent inducer of apoptosis via cytochrome c release from the mitochondria.

• Journal of Pharmaceutical Investigation
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• 제34권1호
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• pp.57-71
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• 2004

The objective of this study was to provide a better understanding of SUPAC-IR and its application in handling postapproval changes to immediate release solid oral dosage forms. Originally, SUPAC-IR was aimed at reducing the regulator burdern of the industry when they were making postapproval changes, but still at maintaining the formulation quality and performance of a drug product. The postapproval changes that were covered under SUPAC-IR included variations in the components ad composition of formulation, the site of manufacturing, batch size, manufacturing equipment, and manufacturing process. The guidance defined levels of changes, based on the likelihood of risk ocurrence and potential impact of postapproval changes upon the safety and efficacy of a drug product I suggested what a type of fing report should be submitted to the FDA for each level of change. Chemist, manufacturing, and control tests to be executed were also recommended for each change level The important tests specified in the guidance included batch release, stability, in vitro dissolution, and in vivo bioequivalence tests. However, there have been strong demands on revising the current SUPAC-IR in order to resolve some issues and to improve its usefulness in evaluating postapproval changes to immediate release solid oral dosage forms. In particular, the rigorous requirement of case C dissolution test and the definition of batch size were challenged by both academia and the industry. A revision work was in progress to reflect these inputs and to expand the utility of SUPAC-IR. As a result of these concerted efforts, an updated 2nd version of SPAC-IR would be likely to be issued ver soon to the public.

• 한국환경생태학회지
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• 제38권1호
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• pp.79-89
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• 2024

본 연구는 국립공원계획 타당성검토의 구역조정 기준과 방법을 한려해상국립공원에 적용하여 평가 하는 것을 목적으로 하였다. 구역조정 대상지 도출에 이용되는 생태기반평가 결과 편입 검토가 가능한 생태기반평가 I등급은 10.0%, II등급 40.4%로 분석되었다. 해제 검토가 가능한 V등급은 9.9%이었다. 편입 및 해제 적합성 평가 결과 편입대상 면적은 35.150km²(육상 3.669km², 해상 31.481km²)이었고 해제 대상 면적은 육상 0.071km²이었다. 지자체와 지역주민이 공익상 또는 주민편의를 위해 공원구역 해제를 요구하는 곳에서는 총 면적이 변화되지 않는 범위 내에서 해제 검토가 가능하며, 이것을 상호교환이라 한다. 상호교환에 의해 결정된 해제 면적은 10.386km²이었다. 이것은 해제 적합성 평가에 의해 도출된 면적의 146배에 달했다. 상호교환으로 해제되는 지역을 생태기반평가와 매칭한 결과 해제를 절대 할 수 없는 I,II등급에 해당하는 곳이 70.6%(7.321km²) 이었다. 결과적으로 한려해상국립공원 타당성검토의 구역조정은 생태기반평가나 해제 적합성 평가 결과가 매우 제한적으로 적용되었음을 알 수 있었다. 또한 상호교환이 국립공원 계획 타당성검토 중 구역조정의 핵심이었다.