• Title/Summary/Keyword: public medicine

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Involvement of P38 Mapk and Gap Junctional Intercellular Communication (Gjic) in 12-O-Tetradecanoyl Phorbol 13-Acetate-Induced Stellation of Neurosphere-Derived Cells

  • Yang, Se-Ran;Ahn, Nam-Shik;Jung, Ji-Won;Park, Joon-Suk;Yoon, Byoung-Su;Lee, Yong-Soon;Kang, Kyung-Sun
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.123-123
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    • 2003
  • Primary cultures of rat fetus brain exhibit phenotypes of neuron, oligodendrocyte, and astrocyte from "neurospheres". To understand the role of mitogen-activated protein kinase (MAPK) cascade and gap junctional intercellular communication (GJIC) in the differentiation of neurosphere-derived astrocyte, we investigated the effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the cultured astrocyte morphology.(omitted)

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Monitoring and Risk Assessment of Benzo(a)pyrene Content in Medicinal Herbs (유통 한약재 중 벤조피렌 함량 모니터링 및 안전성 평가)

  • Lee, Sae Ram;Kim, Ae Kyung;Kim, Sung Dan;Lee, Hyun Kyung;Lee, Hee Jin;Ryu, Hoe Jin;Lee, Jung Mi;Yu, In Sil;Jung, Kweon
    • Korean Journal of Pharmacognosy
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    • v.48 no.3
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    • pp.237-242
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    • 2017
  • In this study, to investigate of safety for Benzo(a)pyrene in medicinal herb, 8 kinds of selected commercial herbal medicines (Rehmanniae Radix, Rehmanniae Radix Preparata, Amomi Tsao-Ko Fructus, Cimicifugae Rhizoma, Cyperi Rhizoma, Magnoliae Cortex, Scutellariae Radix, Scrophulariae Radix) were analysed using the high performance liquid chromatography with fluorescence detector and assessed the health risk. The levels of benzo(a)pyrene were from non-detection to $28.1{\mu}g/kg$, and the average was $3.6{\mu}g/kg$. Based on a nationwide survey of the consumption of medicinal herb by the Korean population, we estimated the potential risk from the ingestion of benzo(a)pyrene. The estimated daily intake of benzo(a)pyrene was 1.6 ng/kg b.w./day for group only know the daily average intake of medicinal herb. The MOE (margin of exposure) of benzo(a)pyrene for estimate of health risk was $1.93{\times}10^5$. Therefore, health risk from benzo(a)pyrene through intake of herbal medicine was considered negligible.

A Study for Management and Effects of Children's Care Program with Traditional Korean Medicine in Public Health Center (보건소 건강증진 사업 중 한방육아교실의 운영과 효과에 관한 연구)

  • Park, Eun-Seong;Moon, Yeun-Hee;Kim, Yang-Hee;Choi, Kyung-Hee;Jang, Dong-Wook
    • The Journal of Korean Medicine
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    • v.33 no.1
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    • pp.52-67
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    • 2012
  • Objectives: The purpose of this study was to evaluate the effects and develop the contents of a children's care program with traditional Korean medicine in a public health center. Methods: Data were collected from 28 parents who participated in a children care program with traditional Korean medicine. The program was started in June of 2011 in Gangjin-Gun public health center and finished in September of the same year. The questionnaires to measure effect and satisfaction with the program were composed of demographic items, family information, Psychological Well-Being Scale (PWBS), Parenting Stress Index (PSI), children health improvement checklist, etc. The questionnaires were executed before and after the program. Results: The PWBS scores increased (4.00, 3.66) and PSI scores decreased (-7.30. -5.95) significantly after the program. The satisfaction with the program was 100%, and 94% in the two groups, and treatment and lecture were mentioned as the best aspects of the program. Eating habits, sleep conditions, and activity also improved after the program. Conclusions: From these results, the children care program with traditional Korean medicine is worthy for improving children's health condition and reducing their parents' stress.

Designing Online Public Education Contents in Korean Medicine Using the Rapid-Prototyping Instructional Systems Design Model

  • Jiseong Hong
    • The Journal of Korean Medicine
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    • v.43 no.4
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    • pp.74-88
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    • 2022
  • Objectives: The purpose of this study is to design Korean-themed online public education content in Korean medicine using rapid prototyping instructional systems design (RPISD). This study presents cases of developing and converting face-to-face general education programs designed to increase the interest in and understanding of Korean medicine for the public into online programs within a short timeframe. Methods: This qualitative study is design and development research, which used the RPISD model to analyze the available resources utilized in the rapid development of public educational content and propose systematization and optimization measures by analyzing the needs of clients, learners, and the environment. The <Treasured Mirror of Eastern Medicine(DUBG)Open Course> was developed according to the model procedure, which involved needs analysis, development of course materials and manuscript, and storyboard creation and its filming and editing. Usability tests were conducted at all stages, and the opinions of clients, instructors, experts, and instructional designers were accommodated and reflected at each stage. Results: Using the rapid prototyping model, <Treasured Mirror of Eastern Medicine(DUBG)Open Course> was organized into five classes of 20 minutes each. Each class was developed in Korean and included English, Chinese, and Japanese subtitles in addition to Korean under the cooperative instructional design among clients, subject-matter experts, instructional designer and learners. Conclusion: The cooperative instructional design of stakeholders is significant in developing Korean medicine public education content online through extensive interaction and feedback from stakeholders in the early stage of educational content development.