• Title/Summary/Keyword: pseudo-3-D problem

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Physiological Activity of Robinia pseudo acacia Leaf Extracts and Enhancement of Skin Permeation Using Polymer Micelles and Cell Penetrating Peptide (아카시아 잎 추출물의 생리 활성 및 고분자 미셀과 세포투과 펩티드를 적용한 피부흡수증진 효과)

  • Heo, Soo Hyeon;Park, Su In;An, Gyu Min;Shin, Moon Sam
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.3
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    • pp.271-282
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    • 2019
  • This study was conducted to evaluate physiological activity of Robinia pseudo-acacia leaf and its skin penetration using polymer micelles and skin penetrating peptide. After extraction with Robinia pseudo-acacia using the ethanol and distilled water, various physiological activities were examined. The total concentration of polyphenol compounds was determined to be 47.42 mg/g (ethanol extract), 56.88 mg/g (hydrothermal extract) and DPPH radical scavenging ability at $1,000{\mu}g/mL$ was 44.24% in ethanol extract and it is higher than value(41.50%) in hydrothermal extract. The elastase inhibitory assay showed concentration dependence and elastase inhibition of Robinia pseudo acacia leaf ethanol extract was 54.09%, which was the highest at $500{\mu}g/mL$. In the SOD-like experiments, the concentration-dependent results were showed and the SOD-like activity of the Robinia pseudo-acacia leaf ethanol extract was higher than that of the Robinia pseudo acacia leaf hydrothermal extract at all concentrations. At a concentration of $500{\mu}g/mL$, Robinia pseudo acacia leaf ethanol extract showed the highest SOD-like activity of 76.41%. The tyrosinase inhibition at $20{\mu}g/mL$ was determined to be 56.47% (ethanol extract), 23.05% (hydrothermal extract). In the antimicrobial experiments, the hydrothermal extract had no effect, but ethanol extract represented maximum clear zone of 11.00 mm in Propionbacterium acnes strain and maximum clear zone of 10.50 mm. in Bacillus subtilis strain. To solve the problem of insolubility and to improve skin penetration, PCL-PEG polymer micelles containing Robinia pseudo-acacia leaf ethanol extracts and 1.0% cell permeable peptide, hexa-D-arginine (R6) were successfully prepared with particle size of 108.23 and 126.47 nm and excellent skin permeation effects could be showed.

Development of Rapid Hardening Backfill Material for Reducing Ground Subsidence (지반함몰 저감을 위한 속경형 하수관거 뒤채움재료 개발)

  • Ryu, Yong-Sun;Han, Jin-Gyu;Chae, Woo-Ri;Koo, Ja-Sul;Lee, Dae-Young
    • Journal of the Korean Geosynthetics Society
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    • v.14 no.3
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    • pp.13-20
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    • 2015
  • Inappropriate backfill material and poor compaction cause the damage to sewer and ground settlement. To deal with such problem, flowable backfill material has attracted attention recently. A basic study was conducted in a bid to obtain optimum mixing ratio of backfill material with the characteristics of rapid hardening, pseudo-plasticity, flowability and anti washout ability and enhance the cost efficiency of backfill material. Through the test of optimal mixing ratio of rapid hardening, evaluation of optimal mixing ratio of backfill material was conducted. As a result, required performance as well as cost efficiency could be achieved by adjusting plasticizer even in case of increasing W/M of the paste of rapid hardening to 100%.

Joint Virtual User Identification and Channel Security En/Decoding Method for Ad hoc Network

  • Zhang, Kenan;Li, Xingqian;Ding, Kai;Li, Li
    • International Journal of Computer Science & Network Security
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    • v.22 no.11
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    • pp.241-247
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    • 2022
  • Ad hoc network is self-organized network powered by battery. The reliability of virtual user identification and channel security are reduced when SNR is low due to limited user energy. In order to solve this problem, a joint virtual user identification and channel security en/decoding method is proposed in this paper. Transmitter-receiver-based virtual user identification code is generated by executing XOR operation between orthogonal address code of transmitter and pseudo random address code of receiver and encrypted by channel security code to acquire orthogonal random security sequence so as to improve channel security. In order to spread spectrum as well as improve transmission efficiency, data packet is divided into 6-bit symbols, each symbol is mapped with an orthogonal random security sequence. Subspace-based method is adopted by receiver to process received signal firstly, and then a judgment model is established to identify virtual users according to the previous processing results. Simulation results indicate that the proposed method obtains 1.6dB Eb/N0 gains compared with reference methods when miss alarm rate reaches 10-3.

A Study on Transcranial Magnetic Electrode Simulation Using Maxwell 3D (Maxwell 3D를 이용한 경두개 자기 전극 시뮬레이션에 관한 연구)

  • Lee, Geun-Yong;Yoon, Se-Jin;Jeong, Jin-hyoung;Kim, Jun-Tae;Lee, Sang-sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.12 no.6
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    • pp.657-665
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    • 2019
  • In this study, we conducted a study on the transcranial magnetic electrode, a method for the study of dementia and muscle pain, a neurodegenerative disease caused by an aging society, which is becoming a problem worldwide. In particular, transcranial magnetic electrodes have been studied to improve their ability to be deteriorated by dementia symptoms such as speech, cognitive ability, and memory by outputting magnetism deep into the brain using coils on the head epidermis. In this study, simulation was performed using Maxwell 3D program for the design of coil, the core of transcranial magnetic electrode. As a result of the simulation comparison between the coil designed by the previous research and the coil through the research and development, the output was found to be superior to the conventional designed coil. The graphs of the coil outputs of B-Field and H-Field are found to be symmetrical, but the symmetry between each coil is pseudo-symmetrical and not accurate. Based on these results, an experiment was conducted to confirm whether the output of the head epidermis through both coils is possible. In the magnitude field of the reverse-coil 2-coil analysis, the maximum output was 3.3920e + 004 H [A_per_meter], and the vector field showed the strongest magnetic field around 35 to 165 degrees. It was confirmed that the magnetic output canceled due to the magnetic output. In the case of the forward 2-coil, a maximum of 3.2348e + 004H [A_per_meter] similar to the reverse coil was observed, but in the case of the vector field, the magnetic output regarding the forward output and the head skin output was confirmed. However, when the height change in the output coil, the magnetic output was reduced.