• Title/Summary/Keyword: pseudo stabilizing solution

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Study on Stabilization of Promazine Hydrochloride Injection (염산(鹽酸)Promazine 주사제(注射劑)의 안정화(安定化)에 관한 연구(硏究))

  • Lee, Wan-Ha;Chi, Ung-Kil;Young, Jae-Hun
    • Journal of Pharmaceutical Investigation
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    • v.3 no.3
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    • pp.5-15
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    • 1973
  • The stabilizing effect of promazine hydrochloride injectin was tested by irradiation of sun lamp(5,000 Lux) on their acid solution sealed in ampules under various stabilizers. The result of experimentation on the color change, the remaining proportion and the half life of promazine hydrochloride solution is as follows. 1. Instability of promazine hydrochloride solution is mainly caused by the sunlight and oxygen. 2. The pH range of promazine hydrochloride injection is recommended to $pH\;4.4{\sim}5.2$ 3. The decomposition of promazine hydrochloride by the sunlight is composed of pseudo zero order reaction when It maintains colorless solution. 4. The half life of 0.5% promazine hydrochloride injection was 30 hrs. under sun lamp irradiation, but it was delayed to 84 hrs. by the simple stabilizer and to 175 hrs. by compound stabilizer. 5. The stabilizing effect of promazine .hydrochloride injection adding sod. metabisulfite$(Na_2S_2O_5)$ was most excellent in various simple stabilizers and adding $Na_2S_2O_5$ to nicotinic acid, $Na_2S_2O_5$ to nicotinamide were more excellent than other compound stabilizers.

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Multivariable $H_{\infty}$ disturbance rejection control for tandem cold mills (연속 냉간 압연기의 다변수 $H_{\infty}$ 외란제거 제어)

  • 김승수;김종식
    • 제어로봇시스템학회:학술대회논문집
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    • 1997.10a
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    • pp.391-394
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    • 1997
  • A H$_{\infty}$ control techniques with roll eccentricity filter is proposed to alleviate the effect of entry thickness variation and roll eccentricity occurred in rolling stand itself of tandem cold mills. A robust controller to the disturbances is designed using H$_{\infty}$ control techniques, which can reflect the input direction of disturbances and knowledge of disturbance spectrum in the frequency domain. And, non-standard H$_{\infty}$ control problem caused by selection of weight function having poles on j.omega. axis is discussed. The evaluation for the resultant controller composed by H$_{\infty}$ synthesis is done through computer simulations. The effectiveness of the proposed method is compared to those of the conventional LQ synthesis method and a feedforward controller against roll eccentricity, which was already studied.ied.

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