• Journal of Microbiology and Biotechnology
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• 제34권6호
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• pp.1322-1327
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• 2024

The accurate and rapid detection of methicillin-resistant Staphylococcus aureus (MRSA) holds significant clinical importance. This work presents a new method for detecting methicillin-resistant Staphylococcus aureus (S. aureus) in clinical samples. The method uses an aptamer-based colorimetric assay that combines a recognizing probe to identify the target and split DNAzyme to amplify the signal, resulting in a highly sensitive and direct analysis of methicillin-resistance. The identification of the PBP2a protein on the membrane of S. aureus in clinical samples leads to the allosterism of the recognizing probe, and thus provides a template for the proximity ligation of split DNAzyme. The proximity ligation of split DNAzyme forms an intact DNAzyme to identify the loop section in the L probe and generates a nicking site to release the loop sequence ("3" and "4" fragments). The "3" and "4" fragments forms an intact sequence to induce the catalytic hairpin assembly, exposing the G-rich section. The released the G-rich sequence of LR probe induces the formation of G-quadruplex-hemin DNAzyme as a colorimetric signal readout. The absorption intensity demonstrated a strong linear association with the logarithm of the S. aureus concentration across a wide range of 5 orders of magnitude dynamic range under the optimized experimental parameters. The limit of detection was calculated to be 23 CFU/ml and the method showed high selectivity for MRSA.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.245-246
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• 1998

AMB(Active Magnetic Bearing) systems are popularly used in various areas. In biomedical engineering applications it is a key part of magnetically suspended rotary blood pumps. The special advantage of AMBs is that they enable the rotor to revolve with no physical contact and provide rotary blood pumps with better performances such as low hemolysis level. Fundamentally, AMB systems consist of three parts, proximity sensors for distance detection, microprocessor for control algorithm and power amplifiers for actuating electromagnets. We have developed an inductive type proximity sensor with satisfactory characteristics that can be used in AMB systems. Frequency response was flat at least up to 10 kHz and sensitivity, resolution$(>5{\mu}m)$ and sensing range(<5mm) of the sensor could be adjustable for various purposes. The characteristics of the completed model showed to have satisfactory behaviors compared with the commercially available ones that already appeared to have reliable behaviors in AMB systems.

• 한국지능시스템학회논문지
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• 제22권6호
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• pp.729-734
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• 2012

패턴 인식, 데이터 분석, 침입 탐지, 이미지 처리, 바이오 인포매틱스 등과 같은 수많은 분야에서 클러스터링 분석이 사용되고 있다. 기존의 많은 연구들은 수치 데이터에만 기반을 두고 있다. 그러나 구간 데이터, 히스토그램, 심지어는 함수들을 값으로 갖는 변수들을 다루는 심볼릭 데이터 분석이 부상하고 있다. 본 논문에서는 이런 심볼릭 데이터들을 클러스터링하기 위하여 비대칭적 유사도를 제안한다. 또한 평균 유사도 값(ASV)에 기반한 클러스터링 방법도 개발한다. 제안하는 클러스터링의 결과는 기존 방법들과 다르며, 매우 고무적인 결과를 보여준다.

• 한국군사과학기술학회지
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• 제16권1호
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• pp.81-88
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• 2013

This paper describes the fundamentals, design, realization and test results of a BPSK(Bi Phase Shift Keying) transceiver for the direction finding proximity fuze sensor for anti-aircrafts or air missiles. The BPSK transceiver for the direction finding fuze sensor has been designed to detect a moving target by Doppler signal processing with the code correlation method and to distinguish direction by comparing received powers of each Doppler signal from adjacent three receiving antennas. The electrical and ESS(Environmental Stress Screening) tests of the BPSK transceiver showed satisfactory results and target detection and direction finding performances proved to be successful through dynamic operation tests by 155 mm gun firing.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 D
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• pp.2374-2376
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• 2001

In this paper we have developed a Power Line Proximity Detecting device for Mobile Crane by using a Derivation Electric-Potential Detection method. A mobile crane worker can be easily exposed to a dangerous electrical shock and the electrocution while they are working at near the high-voltage electrical lines. The derivation electric-potential of the power lines have been simulated in our experiment, Also, microprocessor-based detecting device and transmitter/receiver modules are introduced to show a solution for the dangerous mobile crane working environment. As a result, It has been shown a good functional field test.

• 한국환경농학회:학술대회논문집
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• 한국환경농학회 2009년도 정기총회 및 국제심포지엄
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• pp.187-199
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• 2009

We present real.time, rapid detection of Mycoplasma pneumonia in phosphate buffered saline (PBS) inside a Y.channel polydimethylsiloxane (PDMS) microfluidic device by means of optical fiber monitoring of latex immunoagglutination. The latex immunoagglutination assay was performed with serially diluted Mycoplasma pneumonia solutions using highly carboxylated polystyrene particles of 390nm and 500nm diameter conjugated with monoclonal anti. Mycoplasma pneumonia . Proximity optical fibers were located around the viewing cell of the device, which were used to measure the increase in 45${\b{o}}$ forward light scattering of the immunoagglutinated particles. The detection limit was less than 50 $pgml^{-1}$ both for 390nm and 500nm microspheres with the detection time less than 90 seconds.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제15권4호
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• pp.275-279
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• 2009

미국과 유럽 연합 등을 포함한 여러 나라에서 통신 서비스 제공자들에 게 통신 기록들을 일정 기간 보관하도록 의무화하고 있다. 저장된 통신 기록들은 범죄의 수사 및 감시, 기소 등의 목적으로 사용되지만, 그 크기가 매우 크다. 저장된 통신 기록으로부터 범죄자들과 용의자들의 관련성과 같은 정보를 효율적으로 추출하기 위해, 통신 기록의 대부분을 차지하는 불필요한 데이터를 제거해야 한다. 본 논문에서는 통신 기록들을 이용하여 통신 객체들 사이의 친밀도를 측정하는 방법을 제안한다. 주요 감시 대상자들이 주어졌을 때, 측정된 친밀도는 감시 대상자와의 친밀도 크기에 따른 데이터의 선별적인 분석 흑은 낮은 친밀도를 갖는 데이터의 제거 등에 사용될 수 있다. 실험 결과는 제안된 방법에 의해 계산된 친밀도 결과와 사람에 의해 계산된 결과가 서로 상관관계를 갖고 있음을 보여준다.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2015년도 제52차 하계학술대회논문집 23권2호
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• pp.279-281
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• 2015

Location awareness is an important capability for mobile-based indoor services. Those indoor services have motivated the implementation of methods that need high computational load cost and complex mechanisms for positioning prediction. These mechanisms, such as opportunistic sensing and machine learning, require more energy consumption to achieve accuracy. In this paper, we propose the Bluetooth Low Energy indoor zone detection (BLEIZOD) technique. This method exploits the concept of proximity zone to reduce the load cost and complexity. Our proposed method implements the received signal strength indicator (RSSI) function more effectively to gain accuracy and reduce energy consumption.

• 한국정밀공학회지
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• 제6권4호
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• pp.119-125
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• 1989

This paper presents a method of analog signal processing for a coordinate transformation. Through the proposed method, two-dimensional position information obtanided from any type of null-detector can be transformed into the information with repect to world coordinate system. In order to implement the method, a null- detection device which consists of four optical proximity sensor is developed. Through the experiments for performance evaluation, the effectiveness of the proposed method has been demonstrated.

• 전기전자학회논문지
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• 제23권1호
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• pp.310-313
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• 2019

This paper used the majority function to digitally filter back-electromotive force as an explanation of the Brushless DC MOTOR control algorithm. The cause and improvement of motor noise, which are operating in close proximity to high frequency sources, did not use conventional low pass filter and comparator elements. Also, they repeatedly output a noise-free BEMF signal for the input value of the majority detection filtering. These filtering steps can help reduce costs and minimize the area of a PCB by requiring relatively little hardware.