• Journal of Korean Ophthalmic Optics Society
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• v.10 no.2
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• pp.91-97
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• 2005

We investigated the question whether protein removing activities of enzyme cleaner - protein remover for soft contact lens - are associated with the material of soft contact lens as well as action time, temperature and pH of enzyme solution. We used a subtilisin cleaner as protein remover and estimated the protein amount remained on soft contact lens after using the subtilisin cleaner under the different conditions. The remained protein in soft contact lens was greatly decreased until treatment for 60min, but no significant differences were found from 60min to 24hr. The cleaning effect of the enzymatic treatment in the range of $15{\sim}30^{\circ}C$ was constant. however, there was a significant decline of the protein removing effect at $10^{\circ}C$ and less. The pH of the solution was also important for the efficacy of the enzymatic treatment. The activity of the enzyme cleaner was highest in pH 8.0 and significantly decreased a pH below 7. The pH dependence was found to be related to the conformational change of subtilisin. Furthermore, significant differences in the protein deposit removing efficacy of the subtilisin cleaner were found among the soft contact lens materials.

• The Journal of the Convergence on Culture Technology
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• v.6 no.2
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• pp.183-190
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• 2020

This study was designed to investigate the current state of lens wearing and care, and to investigate eye discomfort according to the care method. Data of 209 female college students wearing lenses for more than 1 year were analyzed using the SPSS / WIN 22.0 program. 40.2% of female students wear lenses every day and 97.1% wear all day. However, only 45.4% of students washed it daily, and only 17.7 % used protein remover during wash, which resulted in poor management. 98.1% of students complained of discomfort due to the lens, and the Ocular Surface Index (OSDI) scored 42.88 ± 15.25, which was classified as a severe dry eye and threatened eye health. Therefore, it is necessary to improve students' awareness of lens management, and periodical lens inspection and management education are needed.