• 제목/요약/키워드: protein losing enteropathy

검색결과 23건 처리시간 0.019초

Disseminated Cytomegalovirus Infection and Protein Losing Enteropathy as Presenting Feature of Pediatric Patient with Crohn's Disease

  • Cakir, Murat;Ersoz, Safak;Akbulut, Ulas Emre
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제18권1호
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    • pp.60-65
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    • 2015
  • We report a pediatric patient admitted with abdominal pain, diffuse lower extremity edema and watery diarrhea for two months. Laboratory findings including complete blood count, serum albumin, lipid and immunoglobulin levels were compatible with protein losing enteropathy. Colonoscopic examination revealed diffuse ulcers with smooth raised edge (like "punched out holes") in the colon and terminal ileum. Histopathological examination showed active colitis, ulcerations and inclusion bodies. Immunostaining for cytomegalovirus was positive. Despite supportive management, antiviral therapy, the clinical condition of the patient worsened and developed disseminated cytomegalovirus infection and the patient died. Protein losing enteropathy and disseminated cytomegalovirus infection a presenting of feature in steroid-naive patient with inflammatory bowel disease is very rare. Hypogammaglobulinemia associated with protein losing enteropathy in Crohn's disease may predispose the cytomegalovirus infection in previously healthy children.

단백 소실성 장병증을 동반한 교착성 심낭염 1례 (A case of constrictive pericarditis presenting with protein-losing enteropathy)

  • 홍정미;이재영;김수진;장기영;심우섭
    • Clinical and Experimental Pediatrics
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    • 제49권8호
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    • pp.898-901
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    • 2006
  • 소아에서 교착성 심낭염은 매우 드문 질환으로 이에 의하여 단백 소실성 장병증이 동반되는 경우는 더욱 드물다. 저자들은 교착성 심낭염의 주요 증상의 하나로 단백 소실성 장병증을 보인 여아 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

전신성 홍반성 루푸스에서 고용량 경정맥 당질코르티코이드로 치료된 단백질 소실성 장질환 1예 (A Case of Protein-losing Enteropathy Treated with High Dose Intravenous Glucocorticoid Therapy in Systemic Lupus Erythematosus)

  • 이규형;권창모;김현도;윤대영;이재웅;홍영훈;이충기
    • Journal of Yeungnam Medical Science
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    • 제22권2호
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    • pp.253-258
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    • 2005
  • Generalized edema and hypoalbuminemia are relatively common presenting manifestations in many clinical situations. The differential diagnosis of hypoalbuminemia include: Kwashiorkor, synthetic dysfunction of the liver, and excessive protein loss as in nephrotic syndrome. In systemic lupus erythematosus (SLE), hypoalbuminemia and generalized edema are most commonly due to protein loss associated with lupus nephritis; gastrointestinal involvement is uncommon, and therefore protein loss through the gastrointestinal tract is quite rare. We report a case of a protein losing enteropathy (PLE) associated with SLE. The patient was referred to our hospital for generalized edema, arthralgia and facial rash. After clinical evaluation, the patient met the criteria for the SLE diagnosis; hypoalbuminemia with general edema was consistent with a protein losing enteropathy. After two weeks of therapy with parenteral high dose glucocorticoid, the patients was improved in laboratory findings as well as clinical symptoms.

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Henoch-Schönlein 자반증에서 발생된 단백소실장증 1례 (A Case of Protein Losing Enteropathy Associated with Henoch-Schönlein Purpura)

  • 김기대;오창환;이은영;김재영
    • Clinical and Experimental Pediatrics
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    • 제48권2호
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    • pp.224-227
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    • 2005
  • Henoch-$Sch{\ddot{o}}nlein$ 자반증에서 복통과 혈변이 가장 흔한 위장관계 침범 증상이며, 주요 위장관계 합병증은 발생빈도가 매우 낮다. 특히 국내 소아에서 단백소실장증이 합병된 보고 예는 아직까지 없다. 저자들은 Henoch-$Sch{\ddot{o}}nlein$ 자반증에서 경과 중에 단백소실장증이 합병된 6세 여아를 경험하였기에 문헌고찰과 함께 보고한다.

단백 소실 장증으로 발현한 연소성 용종증 1례 (A Case of Juvenile Polyposis Presented with Protein Losing Enteropathy)

  • 강보영;한승정;이지은;최선근;김준미;홍영진;손병관
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제6권2호
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    • pp.208-214
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    • 2003
  • 저자들은 전신부종과 심한 저알부민혈증으로 내원한 환아에서 테그네슘표지 인혈청알부민 스캔을 이용하여 결장에서 단백이 소실되는 것을 확인하고, 바륨 관장 대장 조영술 검사, 상부 위장관 촬영, 소장 조영술, 대장과 십이지장 내시경 검사를 통해 단백 소실 장증으로 발현한 연소성 용종증을 진단하여, 전대장 절제술 후 단백 소실 장증이 호전된 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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An Indigenous Case of Intestinal Capillariasis with Protein-Losing Enteropathy in Korea

  • Jung, Woon Tae;Kim, Hyun Jin;Min, Hyun Ju;Ha, Chang Yoon;Kim, Hong Jun;Ko, Gyung Hyuck;Na, Byoung-Kuk;Sohn, Woon-Mok
    • Parasites, Hosts and Diseases
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    • 제50권4호
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    • pp.333-337
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    • 2012
  • We encountered an indigenous case of intestinal capillariasis with protein-losing enteropathy in the Republic of Korea. A 37-year-old man, residing in Sacheon-si, Gyeongsangnam-do, admitted to the Gyeongsang National University Hospital (GNUH) due to long-lasting diarrhea, abdominal pain, anasarca, and weight loss. He recalled that he frequently ate raw fish, especially the common blackish goby (Acanthogobius flavimanus) and has never been abroad. Under the suspicion of protein-losing enteropathy, he received various kinds of medical examinations, and was diagnosed as intestinal capillariasis based on characteristic sectional findings of nematode worms in the biopsied small intestine. Adults, juvenile worms, and eggs were also detected in the diarrheic stools collected before and after medication. The clinical symptoms became much better after treatment with albendazole 400 mg daily for 3 days, and all findings were in normal range in laboratory examinations performed after 1 month. The present study is the 6th Korean case of intestinal capillariasis and the 3rd indigenous one in the Republic of Korea.

4가지 다른 병인들에 의해 유발된 단백소실성 장병증 증례 (Protein-losing Enteropathy Induced by 4 Different Etiologies)

  • 조규완;문종현;이희천;권도형;강병택;서정향;정동인
    • 한국임상수의학회지
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    • 제29권1호
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    • pp.93-97
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    • 2012
  • Four dogs (case 1; 2-year-old spayed female Schnauzer, case 2; 3-year-old spayed female Cocker Spaniel, case 3; 9-year-old castrated male Yorkshire Terrier, and case 4; 9-year-old intact female Shih-tzu) were referred to us with gastrointestinal signs such as diarrhea, vomiting, and anorexia. Results of blood analysis revealed hypoproteinemia and hypoalbuminemia in all dogs. Case 4 showed large circular mass which is connected with small intestine on abdominal ultrasonography and other 3 cases showed no remarkable findings on abdominal radiography and ultrasonography. We performed enterectomy in case 4 and gastrointestinal endoscopic examination with biopsy in other 3 patients. Finally, 4 patients diagnosed to protein losing enteropathy with 4 different etiologies.

Resolution of Protein-Losing Enteropathy after Congenital Heart Disease Repair by Selective Lymphatic Embolization

  • Kylat, Ranjit I;Witte, Marlys H;Barber, Brent J;Dori, Yoav;Ghishan, Fayez K
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제22권6호
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    • pp.594-600
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    • 2019
  • With improving survival of children with complex congenital heart disease (CCHD), postoperative complications, like protein-losing enteropathy (PLE) are increasingly encountered. A 3-year-old girl with surgically corrected CCHD (ventricular inversion/L-transposition of the great arteries, ventricular septal defect, pulmonary atresia, postdouble switch procedure [Rastelli and Glenn]) developed chylothoraces. She was treated with pleurodesis, thoracic duct ligation and subsequently developed chylous ascites and PLE (serum albumin ${\leq}0.9g/dL$) and was malnourished, despite nutritional rehabilitation. Lymphangioscintigraphy/single-photon emission computed tomography showed lymphatic obstruction at the cisterna chyli level. A segmental chyle leak and chylous lymphangiectasia were confirmed by gastrointestinal endoscopy, magnetic resonance (MR) enterography, and MR lymphangiography. Selective glue embolization of leaking intestinal lymphatic trunks led to prompt reversal of PLE. Serum albumin level and weight gain markedly improved and have been maintained for over 3 years. Selective interventional embolization reversed this devastating lymphatic complication of surgically corrected CCHD.

교원병에 동반된 단백소실장질환(Protein Losing Enteropathy)에서의 테크네슘표지 인혈청알부민 스캔 (Diagnosis of Protein Losing Enteropathy in Connective Tissue Diseases with $^{99m}Tc$-human Serum Albumin(HSA))

  • 원경숙;오영석;방신호;박원
    • 대한핵의학회지
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    • 제27권1호
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    • pp.88-97
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    • 1993
  • Anterior abdominal scintigraphy after intravenous injection of $^{99m}Tc$-human serum albumin ($^{99m}Tc$-HSA 20 mCi) was done in 16 patients with connective tissue diseases and 15 healthy control patients. Patients with proteinuria or hepatopathy were excluded. 1) 7 (44%) patients among 16 connective tissue disease patients without the apparent evidence of external protein loss showed abnormal intestinal accumulation of albumin. 6 patients with positive albumin scintigraphy showed bypoalbuminemia. 2) There was no false positive scintigraphic finding in control group. 3) The serum albumin level in connective tissue disease patients ($3.1{\pm}0.6 g/dl$, n=16) was lower than control patients ($3.9{\pm}0.3 g/dl$, n=15) (p<0.0001). 4) The serum albumin level was lower in connective tissue disease patients with positive $^{99m}Tc$-HSA scan ($2.8{\pm}0.6 g/dl$, n=7) than the connective tissue disease patients with negative scan ($3.3{\pm}0.3 g/dl$, n=9) (p<0.05). 5) The hemoglobin level in connective tissue disease patients with positive nan ($10.6{\pm}2.91 g/dl$) was lower than that of the control group ($13.6{\pm}1.5 g/dl$) (p<0.05). Mypoalbuminemia is frequently involved in chronic connective tissue diseases. Protein losing enteropathy (PLE) is also responsible for the majority of the bypoalbuminemia in these patients. But it has been ignored because the conventional method for the diagnosis of PLE was difficult to perform. $^{99m}Tc$-HSA scan also must be validated by more extended study and comparison with the quantitative study such as stool ${\alpha}-1$ antitrypsin measurement. There must be a reevaluation of PLE in various diseases especially in connective tissue diseases with easy, fast, economical, and non-invasive method.

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