• 제목/요약/키워드: progressive modeling

검색결과 101건 처리시간 0.032초

The Influence of Comorbidities on Reoperations Following Primary Surgery of Lumbar Degenerative Diseases : A Nationwide Population-Based Retrospective Cohort Study from 2009-2016

  • Park, Hyung-Ki;Park, Su-Yeon;Lee, Poong-Hhoon;Park, Hye-Ran;Park, Sukh-Que;Cho, Sung-Jin;Chang, Jae-Chil
    • Journal of Korean Neurosurgical Society
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    • 제63권6호
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    • pp.730-737
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    • 2020
  • Objective : Spinal degeneration is a progressive disease, worsening over time. Lumbar degenerative disease (LDD) is a major spinal disease in elderly patients. Surgical treatment is considered for medically intractable patients with LDD and reoperation after primary surgery is not uncommon. The surgical outcome is occasionally unpredictable because of comorbidities. In the present study, the relationship between comorbidities and the incidence of reoperation for LDD over time was determined. Methods : The claims data of the health insurance national database were used to identify a cohort of patients who underwent spinal surgery for LDD in 2009. The patients were followed up until 2016. Medical comorbidity was assessed according to the Charlson comorbidity index (CCI). Cox proportional hazard regression modeling was used to identify significant differences in sex, surgery, age, causative disease, and comorbidity. Results : The study cohort included 78241 patients; 10328 patients (13.2%) underwent reoperation during the observation period. The reoperation rate was statistically higher (p<0.01) in males, patients 55-74 years and 65-74 years of age, and patients with decompression or discectomy. Significant association was found between increasing reoperation rate and CCI score (p<0.01). Based on multivariate analysis of comorbidities, the significantly higher reoperation rates were observed in patients with peripheral vascular disease, pulmonary lung disease, peptic ulcer, diabetes, and diabetes complications (p<0.01). Conclusion : The study results indicate the reoperation rate for LDD is associated with patient comorbidities. The comorbidities identified in this study could be helpful in future LDD studies.

TOPS 위성 SAR 모드 시스템 구현 및 성능 평가 연구 (SPACEBORNE TOPS SAR SYSTEM MODELING AND PERFORMANCE ANALYSIS)

  • 강서리;송정환;김범승;김현철;이우경
    • 한국위성정보통신학회논문지
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    • 제9권2호
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    • pp.74-79
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    • 2014
  • 전통적인 스캔모드는 과거 Envisat이나 Radarsat 위성 등에서 사용되면서 환경 감시 및 관측 분야에 높은 효율성을 지닌 영상 획득을 수행하였으나 해상도의 저하 및 안테나 패턴의 왜곡으로 인해 영상 품질 저하 문제가 지적되어왔다. 최근 이러한 스캔 모드 영상의 단점을 극복하기 위한 새로운 운용 모드로서 TOPS SAR 기법이 제안되어 운용단계에 접어들었다. TOPS 모드는 단일 위성에서 높은 품질의 광역 관측 레이더 영상을 제공하지만 이를 실제로 구현하기 위해서는 매우 복잡한 시스템 설계 능력이 요구된다. 본 논문에서는 TOPS 모드의 원리에 대해 소개하고, 모의 실험을 통하여 TOPS 모드의 동작을 구현한다. SAR 원시데이터를 가상으로 생성한 후 방위방향 안테나 패턴을 스캔 모드와 비교하여 TOPS 모드에서 스캔모드의 단점인 영상 품질 왜곡이 억제됨을 보인다.

기상학회 60년간 환경분야 연구 역사와 전망 (60-Year Research History and Future Prospects in Environment Field in Korean Meteorological Society)

  • 김철희;박록진;김상우;이영희;이상현;송창근
    • 대기
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    • 제33권2호
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    • pp.173-195
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    • 2023
  • Research papers in the field of atmospheric environment published in three Journals: Journal of Korean Meteorological Society, Atmosphere, and Asia-Pacific Journal of the Atmospheric Sciences, are all summarized over period of 60 years since the establishment of Korea Meteorological Society (KMS) in 1963. In addition, current research trends and future outlook in the atmospheric environment field has been also highlighted. The results of historical records published in three KMS journals indicated that the activities, contents, and scope of researches carried out by KMS members in the field of atmospheric environment have yielded the enormous and rapid progress in each of the all four areas over 60 years. In particular, as the chronological progress of observational instruments and availability of satellite data such as from GEMS can be a great asset to deepen the observational and modeling researches in the current and future studies, it is highly anticipated that the more progressive and in-depth studies can be achievable to abate the air pollutants over the Korea as well as northeast Asia.

A novel design method for improving collapse resistances of multi-story steel frames with unequal spans using steel braces

  • Zheng Tan;Wei-hui Zhong;Bao Meng;Shi-chao Duan;Hong-chen Wang;Xing-You Yao;Yu-hui Zheng
    • Steel and Composite Structures
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    • 제47권2호
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    • pp.253-267
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    • 2023
  • The bearing capacities resisted by the two-bay beams of multi-story planar frames with unequal spans under column removal scenarios differ considerably owing to the asymmetric stress on the left and right beams connected to the failed column and cause the potential for beams with larger span-to-depth ratios to be unable to exert effectively, which is disadvantageous for resisting the vertical load in unequal-span frame structures. To address this problem, the structural measure of adding braces to the weak bays of multi-story unequal-span frames was proposed, with the objective of achieving a coordinated stress state in two-bay beams with unequal spans, thereby improving the collapse resistance of unequal-span frame structures. Before conducting the numerical simulation, the modeling methods were verified by previous experimental results of two multi-story planar frames with and without steel braces. Thereafter, the effects of the tensile and compressive braces on the collapse behavior of the frame structures were elucidated. Then, based on the mechanical action laws of the braces throughout the collapse process, a detailed design method for improving the collapse resistance of unequal-span frame structures was proposed. Finally, the proposed design method was verified by using sufficient example models, and the results demonstrated that the design method has good application prospects and high practical value.

Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation

  • Nak Song Sung;Sun Ho Uhm;Hyun Bae Kang;Nam Seob Lee;Young-Gil Jeong;Do Kyung Kim;Nak-Yun Sung;Dong-Sub Kim;Young Choon Yoo;Seung Yun Han
    • Anatomy and Cell Biology
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    • 제56권4호
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    • pp.494-507
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    • 2023
  • Vascular dementia (VaD) is characterized by progressive memory impairment, which is associated with microglia-mediated neuroinflammation. Polyphenol-rich natural plants, which possess anti-inflammatory activities, have attracted scientific interest worldwide. This study investigated whether Rubus fruticosus leaf extract (RFLE) can attenuate VaD. Sprague-Dawley rats were separated into five groups: SO, sham-operated and treated with vehicle; OP, operated and treated with vehicle; RFLE-L, operated and treated with low dose (30 mg/kg) of RFLE; RFLE-M, operated and treated with medium dose (60 mg/kg) of RFLE; and RFLE-H, operated and treated with high dose (90 mg/kg) of RFLE. Bilateral common carotid artery and hypotension were used as a modeling procedure, and the RFLE were intraorally administered for 5 days (preoperative 2 and postoperative 3 days). The rats then underwent memory tests including the novel object recognition, Y-maze, Barnes maze, and passive avoidance tests, and neuronal viability and neuroinflammation were quantified in their hippocampi. The results showed that the OP group exhibited VaD-associated memory deficits, neuronal death, and microglial activation in hippocampi, while the RFLE-treated groups showed significant attenuation in all above parameters. Next, using BV-2 microglial cells challenged with lipopolysaccharide (LPS), we evaluated the effects of RFLE in dynamics of proinflammatory mediators and the upstream signaling pathway. RFLE pretreatment significantly inhibited the LPS-induced release of nitric oxide, TNF-α, and IL-6 and upregulation of the MAPKs/NF-κB/iNOS pathway. Collectively, we suggest that RFLE can attenuate the histologic alterations and memory deficits accompanied by VaD, and these roles are, partly due to the attenuation of microglial activation.

Accurate theoretical modeling and code prediction of the punching shear failure capacity of reinforced concrete slabs

  • Rajai Z. Al-Rousan;Bara'a R. Alnemrawi
    • Steel and Composite Structures
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    • 제52권4호
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    • pp.419-434
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    • 2024
  • A flat slab is a structural system where columns directly support it without the presence of beam elements. However, despite its wide advantages, this structural system undergoes a major deficiency where stresses are concentrated around the column perimeter, resulting in the progressive collapse of the entire structure as a result of losing the shear transfer mechanisms at the cracked interface. Predicting the punching shear capacity of RC flat slabs is a challenging problem where the factors contributing to the overall slab strength vary broadly in their significance and effect extent. This study proposed a new expression for predicting the slab's capacity in punching shear using a nonuniform concrete tensile stress distribution assumption to capture, as well as possible, the induced strain effect within a thick RC flat slab. Therefore, the overall punching shear capacity is composed of three parts: concrete, aggregate interlock, and dowel action contributions. The factor of the shear span-to-depth ratio (a_v/d) was introduced in the concrete contribution in addition to the aggregate interlock part using the maximum aggregate size. Other significant factors were considered, including the concrete type, concrete grade, size factor, and the flexural reinforcement dowel action. The efficiency of the proposed model was examined using 86 points of published experimental data from 19 studies and compared with five code standards (ACI318, EC2, MC2010, CSA A23.3, and JSCE). The obtained results revealed the efficiency and accuracy of the model prediction, where a covariance value of 4.95% was found, compared to (13.67, 14.05, 15.83, 19.67, and 20.45) % for the (ACI318, CSA A23.3, MC2010, EC2, and JSCE), respectively.

친환경 브랜드 농산물 상품의 브랜드 가치 요인이 브랜드 만족, 신뢰, 충성도에 미치는 영향에 관한 연구 (The Effects of Environmentally-friendly Agricultural Product Brand Value on Brand Satisfaction, Trust and Loyalty)

  • 김태훈;김보영
    • 유통과학연구
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    • 제14권5호
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    • pp.59-70
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    • 2016
  • Purpose - The objectives of this study are described as following. First, the study will establish the concept of Brand Values of Environmentally-friendly agricultural product through theoretical discussion. Second, it shows the effects of Environmentally-Friendly Agricultural Products brand value on Brand Satisfaction, Brand Trust and Brand Loyalty by empirical investigation. Third, in order to provide the methodology of brand development, literature regarding and questionnaire survey were used such as Environmentally-Friendly Agricultural Products Brand Value, Brand Satisfaction, Brand Trust and Brand Loyalty. Based up on the results, the research estimates consumers' relative priorities of Environmentally-Friendly Agricultural Products Brand Value factors in purchase. This research also suggests the consumer oriented new brand development and the progressive direction for the successful launching of Korean Environmentally-Friendly Agricultural Products Brand. Research design, data, and methodology - Because the relative literatures reviewed regarding not only each factor but also the relationships among them, Brand Value was categorized into 4 dimensions: Emotional, Social, Functional, and Epistemic Value. Then, Brand Loyalty was added as an outcome variable and Brand Satisfaction, Brand Trust were also added as mediators. The proposed research model and 13 hypotheses were created and 23 measurement items were developed. A face-to-face questionnaire survey with items concerning the Brand Value of Environmentally-Friendly Agricultural Products is conducted to housewives in metropolitan area in May 2016. Respondent answered about Brand Value, Brand Satisfaction, Brand Trust and Brand Loyalty in preferred Environmentally-Friendly Agricultural Products. 333 copies of the questionnaire were collected and analyzed using SPSS 21.0 and AMOS 20.0 to determine the reliability and validity of the measurements. Results - From the confirmatory factor analysis and a structural equation modeling, the outcomes of these studies were as follows; (1) Three Brand value dimensions, i.e. Emotional Value, Social Value, and Epistemic Value had a significant and positive impact on Brand Satisfaction, but Functional Value did not. (2) Social Value also had an impact on Brand Trust, (3) Brand Satisfaction significantly affected Brand Trust, and Brand Trust influenced on Brand Loyalty, and (4) Brand Satisfaction were perfectly effective in mediation between Emotional Value, Epistemic Value and Brand Trust, and it also partially mediated between Social Value and Brand Trust. Conclusions - According to the result of consumer research on Environmentally-Friendly Agricultural Product brand, 3 dimensions of brand value affected brand satisfaction, and especially Social Value was a significant positive dimension. So, marketers should concern about value proposition of Environmentally-Friendly Agricultural Product to consumers by using premium package design, store identity, and distinctive product. Consumers wanted to get self-esteem, self-regard, and high social position by purchasing it. This study has academic and practical significance, so the findings can be applied to a wide range of brand management strategies. However, there are some limitations; 1) limitation about development of new brand value dimensions, 2) limitation about gender in the area of respondents. Future research should be done with wide range of respondents.

복합재 튜브를 이용한 고속 열차의 에너지 흡수장치에 대한 실험 및 수치해석 연구 (Experimental and Numerical Studies on Composite Tubes for the Energy Absorber of High-speed Train)

  • ;장홍규;신재환;손유나;김천곤
    • Composites Research
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    • 제24권1호
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    • pp.1-9
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    • 2011
  • 본 논문에서는 복합재료 튜브를 이용한 고속 열차의 에너지 흡수장치에 대한 실험 및 수치 해석에 관한 연구를 수행하였다. 논문의 목적은 에너지 흡수장치에 대한 최적의 적층(lay-up) 형태를 알아내는 것으로, quasi static method를 이용한 네 가지 적층 형태에 대한 실험을 수행 하였다: $[0/45/90/-45]_4$, $[0]_{16}$, $[0/90]_8$, $[0/30/-30]_5$, 실험을 위해 초기 파괴 시작점을 생성하고, 일정 방향으로 진행되는 파괴를 만들기 위해 베벨 엣지(bevel edge)와 노치 엣지(notch edge)의 두 가지 트리거링 방법을 이용하였다. 저속 충돌실험 결과 $[0/45/90/-45]_4$의 적층 형태가 다른 방법과 비교해서 가장 좋은 에너지 흡수 결과를 보여주였다. 수치해석을 위해 LS-DYNA 프로그램의 변수 분석(parametric analysis)을 통해 가장 적합한 복합재료의 quasi static 실험 시뮬레이션 방법 연구를 수행하였다. 움직이는 벽이 복합재 튜브에 저속 충돌하는 모델을 가정하여 해석을 수행하였으며, 실험값과 수치해석 결과의 비교를 통해 비슷한 경향을 보임을 확인 하였다. 특히 TFAIL과 mass scaling factor를 조절하며 수행하는 변수 분석은 LS-DYNA에서 복합재 튜브의 quasi static 실험을 시뮬레이션 하는 능력과 한계를 보여준다.

의료영상 검사를 위한 상지 보조기구의 3D 프린터 제작 연구 (Study on 3D Printer Production of Auxiliary Device for Upper Limb for Medical Imaging Test)

  • 김형균;윤재호;최성대
    • 대한방사선기술학회지:방사선기술과학
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    • 제38권4호
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    • pp.389-394
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    • 2015
  • 의료영상 검사는 정보기술 및 의료장비의 발달로 인체의 해부학적 구조를 묘사하는 능력이 날로 발전하고 있다. 그러나 상지회전이 필요한 어깨관절 의료영상 검사에서는 인체구조의 복잡성으로 정확한 자세유지가 의료영상의 진단적 가치에 매우 중요하다. 자기공명검사의 경우 긴 검사시간과 고정된 자세가 필요해 검사자의 노력과 환자의 의지만으로 재현성 있는 검사가 불가능하다. 이에 상지회전과 정량적 각도가 가능한 보조기구를 개발하여 진단적 가치가있는 의료영상 검사를 하고자하였다. 본 연구는 선행 연구의 결과를 바탕으로 보조기구를 제작하였으며, 공학용 프로그램인 CATIA 프로그램으로 3차원 모델링을 설계하여, 3D프린터로 최종 완성된 보조기구를 제작하였다. 사용된 3D 프린터는 Stratasys Objet350 Connex 모델이며, 재질은 광경화성 수지를 사용하였다. 완성된 보조기구의 크기는 $120{\times}150{\times}190mm$이며, 손잡이부의 내경은 125.9 mm 로 디자인되었다. 보조기구는 총 4개의 부품으로 바디부(외부), 손잡이부(내부), 고정단자, 연결부로 구성되었으며 바디부와 손잡이부는 원활한 회전이 가능하도록 2.1 mm의 유격이 유지되도록 하였다. 손잡이부에는 360o 눈금선을 표시하여 환자마다 관찰에 필요한 회전각도를 기록할 수 있도록 하여 추적검사나 양쪽검사에 적용할 수 있도록 하였다.

입자기반 개별요소모델을 이용한 암석 균열의 Thermoshearing 거동 해석: 국제공동연구 DECOVALEX-2023 Task G (Grain-Based Distinct Element Modeling of Thermoshearing of Rock Fracture: DECOVALEX-2023 Task G)

  • 박정욱;장리;윤정석;박찬희;손장윤;이창수
    • 터널과지하공간
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    • 제32권6호
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    • pp.568-585
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    • 2022
  • 본 연구에서는 3차원 입자기반 개별요소모델(grain-based distinct element model, GBDEM)을 이용하여 암석 균열의 열에 의한 미끄러짐 거동을 해석하였다. 이는 DECOVALEX-2023 프로젝트 Task G에 참여하여 수행한 연구로, 해석대상은 한국건설기술연구원에서 수행된 saw-cut 균열 시료에 대한 열-역학적 하중 재하 실험 결과이다. 여기에서는 암석 시험편을 Voronoi 다면체의 집합체로 모델링하고, 개별요소법 코드인 3DEC을 통해 입자와 입자 간 경계면, 내부에 포함된 균열에서의 열-역학적 연계거동을 해석하였다. 주요 해석내용은 가열로 인한 암석 표면의 온도 분포, 열응력의 증가에 따른 주응력 변화, 균열의 전단변위와 수직변위이다. 해석 결과, 상기 수치모델은 실내실험에서 관찰된 열전달과 열손실 특성, 열에 의한 균열의 점진적 전단파괴 프로세스, 변위의 제한으로 인한 열응력의 증가 등을 합리적 수준에서 재현하고 있는 것으로 나타났다. 그러나 가열에 의한 전단파괴 시점, 열응력 증분과 변위 크기 등에서는 다소 차이를 보였다. 본 연구의 해석모델은 Task G에 참여하는 국외 연구팀들과의 의견 교류 및 협력을 통해 지속적으로 개선, 검증할 예정이다.