• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.4
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• pp.347-358
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• 2013

When analyzing soft tissue of the profile, Subnasale is often used as an important reference point. But there are few studies on the ideal position of the Subnasale. Therefore, the purpose of this study is to present an objective reference of the esthetic face relating to the change of Subnasale position in Koreans' profile, and also to determine whether there is concordance between professionals and laypersons in their perception of facial attractiveness. The one determined as appropriate profile portion by experts of pictures taken in women in 20s was selected. The photograph was modified changing the Subnasale anteroposteriorly on the plane perpendicular to the true vertical line, while maintaining the nasolabial angle. The photographs were presented to a group of professionals (9 orthodontists) and 126 laypersons, who were asked to assess the facial attractiveness of the photographs on a VAS independently. The conclusion was obtained. 1. The ideal position of the Subnasale is when the ratio of the distance Lateral canthus~Subnasale : Subnasale~Pronasale is 1.769 : 1. 2. The ideal degrees between the true vertical line passing through Nasion and Subnasale is $5.5^{\circ}$ 3. The professionals recognized every change in the ratio, but the laypersons couldn't differentiate between the change from 1.571 : 1 to 1.769 : 1.

• Journal of radiological science and technology
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• v.41 no.5
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• pp.463-469
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• 2018

Morphological information such as shape and margin of micro lesion is important information for diagnosis of disease in clinical imaging. In this study, we investigated the morphological changes of the micro lesions by comparing the contrast and area in grid suppressed DR images according to grid frequency. In the profile analysis of the image, the mass showed an average intensity variation of 8.6 ~ 72.4 after suppression, The higher the grid frequency, the more the contrast was increased. However, in the images obtained using 103 lp / inch, which is a grid frequency less than the sampling frequency, the contrast of the mass in the vertical direction decreased after suppression. In the binary image, the area change of the mass was also large. As a result, the shape, size, and margin of the mass changed. In the case of very small calcification, the higher the grid frequency is the larger the change in contrast, so that a clear image can be obtained in the post-suppression image. However, we could confirm that the margin of the lesion was blurred and the lesion was lost in some of the images using the 103 lp / inch grid. The higher the frequency of the grid, The change of the contrast of fiber occurred largely and clear boundary was confirmed. The decrease of the number of pixels was small and morphological change was small. In conclusion, when using a grid frequency that is not suitable for the sample frequency, morphological changes or lesion loss of micro lesions in the post- suppression image may give the possibility of misdiagnosis in diagnosis and differentiation of the image.

• Journal of Acupuncture Research
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• v.24 no.1
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• pp.151-163
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• 2007

Objectives : Juglandis Semen herbal acupuncture solution(JSS) has a broad array of clinical applications in oriental medicine, including treatment of chronic musculoskeletal diseases such as arthritis. This study was performed to investigate the global gene expression profiles using microarray assay in RAW 264.7 cell line treated with JSS and to advance our understanding of the pharmacologic effect of JSS. Methods : Change of the gene expression profile in RAW cell line following treatment with lipopolysaccharide(LPS) alone, or with LPS plus JSS was investigated with a cut-off level of 2 fold change in the expression. Especially, Change of the gene expression by treatment with LPS alone was compared with that by treatment with LPS plus JSS with a cut-off level of 1/2 fold change in the expression. Results: Of the 8170 genes profiled in this study, 51 were upragulated and 21 downregulated following LPS treatment, and 88 were upregulated and 69 downregulated following costimulation of JSS and LPS. Of the 51 genes upregulated following LPS treatment, 10 were downregulated following costimulation of JSS and LPS. Of the 21 genes downregulated following LPS treatment, 3 were upregulated following costimulation of JSS and LPS. Conclusion : JSS treatment induced upregulation of some genes including IL-10 and downregulation of that including MMP13 with its possible implication in an antiinflammatory action of JSS. However, further research on expression profile changes induced by JSS treatment is expected.

• Tunnel and Underground Space
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• v.23 no.5
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• pp.401-412
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• 2013

Multi-stage shear test has been performed using joint specimens of gneiss, granite and shale to investigate the influence of micro-scale asperity change on the shear strength of joint plane. For each shear test asperity degradation characteristics of joint specimens of different joint surface strength have been analyzed by utilizing the optimum asperity parameter which can reflect the sequential asperity degradation. Elevation of joint surface profile has been measured and both the changes of asperity parameters and micro-scale asperity distribution have been investigated. Two distinctive variation modes of cohesion and friction angle have been delineated and major cause of shear strength parameter change has been analyzed by considering the micro-scale asperity angle change resulting from the abrasion, fracturing and regeneration of micro-scale asperities. Effects of micro-scale asperity variation on the joint shear strength have been also investigated.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.3
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• pp.274-278
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• 2005

Purpose : Prediction for soft tissue change after orthognathic surgery is very important for the final esthetics. In this study, we have tried to get the amount of upper lip movement relative to bony segment movement after anterior segmental osteotomy by cephalmetric analysis to predict final upper lip position after surgery. Material and Methods : 20 patients was studied on whom anterior segmental osteotmy as performed by Cupar method during the years 2002 to 2003. Cephalometric radiograph were taken at 1month before surgery and 6 month after surgery. Change of upper lip was measured on landmark Ls and Sto relative to hard tissue (landmark Ia) setback on these X-rays and analyzed. Results : 1. Upper lip setback movement. Setback of upper lip showed proportional relation to the hard tissue setback and the ratio was about 84%(p=0.001). 2. Upper lip downward movement. Downward movement of upper lip showed no proportional relation to hard tissue setback And the amount was mean 1.38 mm and SD 1.21mm (p=0.922). Conclusion : The posterior movement of upper lip is affected by hard tissue movement and shows good proportional change whereas downward movement is not so much influenced by hard tissue movement. And we think slight downward movement shown in this study could be explained by the V-Y closure performed during surgery.

• Journal of Acupuncture Research
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• v.23 no.4
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• pp.135-148
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• 2006

Objectives : Juglandis Semen herbal acupuncture solution(JSS) has a broad array of clinical applications in oriental medicine, including treatment of chronic musculoskeletal diseases such as arthritis. This study was performed to investigate the global gene expression profiles using microarray assay in RAW 264.7 cell line treated with JSS and to advance our understanding of the pharmacologic effect of Jss. Methods : Change of the gene expression profile in RAW cell line following treatment with JSS alone, with lipopolysaccharide(LPS) alone, or with LPS plus JSS was investigated with a cut-off level of 2 fold change in the expression. Results : Of the 8170 genes profiled in this study, 95 were upragulated and 42 downregulated following JSS treatment, 51 were upragulated and 21 downregulated following LPS treatment, and 88 were upregulated and 69 downregulated following costimulation of JSS and LPS. Conclusion : JSS treatment induced upregulation of some genes including IL-10 with its possible implication in an antiinflammatory action of JSS. However, further research on expression profile changes induced by JSS treatment is expected.

• Asian Journal of Atmospheric Environment
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• v.9 no.1
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• pp.22-30
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• 2015

This study evaluated road shape and roadside barrier impact on near-road air pollution dispersion using FLUENT computational fluid dynamics (CFD) model. Simulated road shapes are three types, namely at-grade, depressed, and filled road. The realizable k-${\varepsilon}$ model in FLUENT CFD code was used to simulate the flow and dispersion around road. The selected concentration profile results were compared with the wind tunnel experiments. The overall concentration profile results show good agreement with the wind tunnel results. The results showed that noise barriers, which positioned around the at-grade road, decrease the horizontal impact distance (In this study, the impact distance was defined as the distance from road surface origin coordinate to the position whose mass fraction is 0.1.) lower 0.33~0.65 times and change the vertical air pollution impact distance larger 2.0~2.27 times than those of no barrier case. In case of filled road, noise barriers decrease the horizontal impact distance lower 0.24~0.65 times and change the vertical air pollution impact distance larger 3.33~3.55 times than those of no barrier case. The depressed road increase 1.53~1.68 times the vertical air pollution impact distance. It contributes the decrease of horizontal air pollution impact distance 0.32~0.60 times compare with no barrier case.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.8
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• pp.1050-1053
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• 2000

Biological evaluation of residual malathion after 168 hrs of single dipping exposure of White Leghorn hens to different concentrations (0, 0.5, 1.0 and 1.5%) of pesticides was investigated. Thirty-two male albino rats divided into four groups of eight each were kept on 20% isoproteinous diet prepared from the meat of these malathion dipped hens. After 30 days feeding trial, the rats were killed by decapitation. No significant change was found in erythrocytes. However, the triglyceride concentration in brain tissue was increased significantly (p<0.05) when dose level of pesticide was 1% in dipping solution. Similarly, malathion exposed poultry meat failed in altering any significant change in the pancreatic amylase and lipase activities of rats. This study concludes the virtual absence of toxic accumulation of pesticide in the meat of birds after 168 hrs of exposure in usual concentration range upto 1.5%.

• Phonetics and Speech Sciences
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• v.2 no.2
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• pp.117-121
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• 2010

The This study aimed to evaluate the effects of the voice therapy we operated to the patients with age-related dysphonia. Thirty four participants who were diagnosed as age-related dysphonia in laryngoscopic finding from January, 2009 to December, 2009 completed the study. The participants were aged from 60 to 82 years old with a mean age of 70.6. All participants had received the abdominal breath technique, SKHPIP with laughter, and basic vocal training with description of their problem, the length of which ranged from four sessions to twelve sessions. We executed the videostroboscopy to compare the aspect of voicing change and the perceptual assessment, voice range profile, acoustic and aerodynamic measures to identify change of voice. Participants had glottal gap due to incomplete glottic closure during voicing on the pretest. After they took the voice therapy, the glottic gap became narrow and rough and breathy voice was reduced. There were significant difference in acoustic and aerodynamic measures. Jitter, Shimmer, MFR were reduced and MPT, Psub were increased(p<.05). Participants' pitch range and intensity range were increased on the posttest performance after taking voice therapy. Especially, most of them were showed that pitch range was increased significantly in high frequency area. The results of this investigation indicate that the voice therapy using abdominal breath, SKHPIP, and exercise together is effective for the patients who have age-related dysphonia to improve their voice quality. We recommend to apply this technique to functional voice disorders who are showed glottal gap.

• Water for future
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• v.19 no.4
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• pp.355-364
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• 1986

This research was carried out to decide both in the field and the laboratory the similarity between the erosion and the accretion in the change of the beach profile. The results obtained were as follows: (1) It was impossible to decide only by C value the similarity between the erosion and the accretion of the actual beach by application of Horikawa's theory. (2) It was difficult to decide the similarity only by values of $H_//L_0$ formula. (3) Observation of dimensionless value of $H_//L_0$ and C, $H_//L_0$ and $L_{sr}$ in the field and the laboratory showed that there was a similarity between the erosion and the accretion which set in at 0.024 of $H_//L_0$. (4) The Knowlege of the wave steepness would help to discriminate the erosion and the accretion.