• Title/Summary/Keyword: primary cultured rat hepartocytes

Search Result 1, Processing Time 0.015 seconds

Hepatoprotective Activity of Salviae miltiorrhizae Radix Extract (단삼(丹蔘) 엑기스의 간보호작용)

  • Eun, Jae-Soon;Lim, Jong-Pil;Park, Yi-Kyu;Yeom, Jeong-Ryeol;Choi, Dong-Seong;Ahn, Moon-Seng
    • Korean Journal of Pharmacognosy
    • /
    • v.22 no.2
    • /
    • pp.95-100
    • /
    • 1991
  • Salviae miltiorrhizae(SM) Radix extract increased $[^3H]-thymidine$ incorporation into rat hepatocytes at the concentration ranging from $5{\times}10^{-5}\;to\;5{\times}10^{-1}mg/ml$. It decreased the activities of s-GOT and s-GPT in cirrhotic rats induced by $CCl_4$, TAA and D-GalN, respectively and reduced the sleeping time induced by hexobarbital in $CCl_4$,TAA and D-GalN intoxicated mice, respectively. SM extract shortened the half-life of sulfobromophthalein in $CCl_4$ intoxicated rats.

  • PDF