• 제목/요약/키워드: primary cultured rat hepartocytes

검색결과 1건 처리시간 0.019초

단삼(丹蔘) 엑기스의 간보호작용 (Hepatoprotective Activity of Salviae miltiorrhizae Radix Extract)

  • 은재순;임종필;박이규;염정렬;최동성;안문생
    • 생약학회지
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    • 제22권2호
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    • pp.95-100
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    • 1991
  • Salviae miltiorrhizae(SM) Radix extract increased $[^3H]-thymidine$ incorporation into rat hepatocytes at the concentration ranging from $5{\times}10^{-5}\;to\;5{\times}10^{-1}mg/ml$. It decreased the activities of s-GOT and s-GPT in cirrhotic rats induced by $CCl_4$, TAA and D-GalN, respectively and reduced the sleeping time induced by hexobarbital in $CCl_4$,TAA and D-GalN intoxicated mice, respectively. SM extract shortened the half-life of sulfobromophthalein in $CCl_4$ intoxicated rats.

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