• 성인간호학회지
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• 제21권2호
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• pp.187-198
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• 2009

Purpose: This study was to compare and examine the factors influencing burden of primary family caregivers according to the severity of illness of elderly patients admitted in an intensive care unit. Methods: Subjects were the families of elderly patients in intensive care units of K, S and Y hospitals in Seoul. Data were collected from March to October 2007. Subjects were 108 persons over age 65. Data were analyzed by SAS statistics. Results: First, groups 5 and 3 showed higher burden than that of group 4. Second, high correlation was found between stress and burden, stress and anxiety, and burden and anxiety. Third, factors influencing family burden were found to be stress for group 5, stress, anxiety, and monthly income for group 4, and stress and patient age for group 3. Conclusion: Specific nursing interventions to decrease the stress of primary family caregivers of serious ill elderly patients in an intensive care unit are needed. Additionally, more effective and systematic activation of a long-term medical insurance system for seriously ill seniors is considered necessary to mediate the burden of primary family caregivers.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1535-1537
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• 2016

Background: Primary myelodysplastic syndrome (MDS) is an acquired clonal disorder of myeloid progenitor cells, characterized by peripheral cytopenias in the presence of hypercellular marrow with dysplastic features. Our aim was to study the demographical and clinicopathological features of adult Pakistani patients with MDS at disease presentation. Materials and Methods: This single centre study was conducted at Liaquat National Hospital and Medical College, extending from January 2010 to December 2014. Data were retrieved from the patient archives. Results: Overall 45 patients were diagnosed at our institution with de novo MDS during the study period. There were 28 males and 17 females. Age ranged between 18 and 95 years with a mean age of $57.6{\pm}17.4years$ and median of 64 years. The male to female ratio was 1.7:1. The main presenting complaints were generalized fatigue (60%), fever (33.3%), dyspnea (15.5%), bleeding (13.3%) and weight loss (11.1%). Examination was unremarkable in 42.2% of patients. Physical examination revealed pallor in 37.7%, followed by petechial and purpuric rashes in 20%. The commonest laboratory finding was anemia (hemoglobin < 10 g/dl in 41 (91.1%) patients. Out of these, 27 (60%) patients had normocytic anemia, followed by macrocytic (22.2%) and microcytic (8.8%). Conclusions: Primary MDS in Pakistani patients demonstrates a male preponderance. The proportion of anemic patients was high in our series with predominance of normocytic anemia. However, other clinico-hematological features appear comparable to published data.

• 대한수사과학회지
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• 제3권1호
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• pp.25-42
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• 2008

As the age of the sex crime perpetrators and victims is going down, the importance of Sex Assault Prevention Education (SAPE) is on the rise. In order to see how many students are aware of the SAPE which are currently being conducted in the local schools. A total of 600 students from five different primary schools in Kyongsan City area were questioned with the questionnaire. On the whole, the level of acknowledgement on the sexual assault is estimated as 20.52 out of total point 53.00. The point in each question is shown as low as follows; The notion of Sexual Assault (9.88 out of 19), recognition of Sexual Assault (5.45 out 11), way to cope with the sexual assault (6.60 out of 11), and knowledge on the symptom induced by the sexual assault (4.04 out of 12). The SAPE should be taught to the student from the young age frequently. The efficiency of SAPE will be increased by the health-care teachers who have the professional knowledge with the case studies and teaching materials like CD-ROMs. The health-care teachers as the SAPE lecturers require continuous training.

• Journal of Chest Surgery
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• 제24권6호
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• pp.631-635
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• 1991

Spontaneous pneumothorax is a rare manifestation of primary lung cancer and it is even more rare as an initial manifestation. Recently we have experienced three cases of lung cancer presenting initially as spontaneous pneumothorax. These three cases involved 2 men and one woman with an average age of 70 years [66 - 74years]. Lung cancer was discovered by explothoracotomy in two cases and by endoscopic biopsy in one case. In pathologic cell types, the one was alveolar cell carcinoma and the others were squamous cell carcinoma. We report these three cases of primary lung cancer presenting initially as spontaneous pneumothorax with review of the literatures.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제32권1호
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• pp.57-61
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• 2010

Objective: Second primary malignancy (SPM) that occur in various period and region are important factors that deteriorate long-term survival rate in patients who recovered from oral cancer. Researches such as chemoprevention are being tried to reduce occurrence of SPMs. Only if analysis of clinical features of patients who develop SPM such as period, region and factors precedes, adequate prevention and treatment of SPM is possible. But, there are few researches about clinical features of SPMs that have primary lesion in oral cavity. In this study, we analysis that occurrence rates, regions that happen, risk factors and effect to survival rates of 2nd primary malignancies in oral cancer patients. From this survey, we willing to collect basic data for prevention and early diagnosis of SPMs. Methods: The medical records of 139 patients of oral oncology clinic of National Cancer Center who had up to 2-years follow up records after surgical or radiological treatment due to squamus cell carcinoma of oral cavity were reviewed. In these patients, survey of occurrence rate of SPMs, duration, survival rate and risk factors about occurrence of SPMs such as history of smoking, body mass index, age, sex, stage of primary lesion and history of radiologic treatment were achieved. Results: There are 15 patients who developed SPM in 139 cases. The actual occurrence rate of SPM was 10.79% and SPM were more likely to occur in male patients with 11 male Vs 4 female patients. Median age of these patient is 61.47 within 32 to 74 range. The regions that develop SPM are oral cavities (2 cases), stomach (4 cases), esophagus (2 cases), lung (2 cases) and others (1 case each breast, larynx, cervix, liver and kidney). In addition, metachronous cancers were 11 cases which happened more common than 4cases of synchronous cancers. Surveys of risk factors that relate to development of SPMs, such as sex, age, history of radiologic treatment, body mass index, history of smoking and stage of primary disease were done. Among them, factor of sex is only appear statistically significant (P=0.001), but rest are not significant in statistically. Conclusion: Occurrence rates of SPMs were reported from 10% to 20% by precede study. In this study, occurrence rate of SPMs is 10.79% that is similar to results of precede research. In comparison of 5-yr survival rates of groups that develop SPMs or not, there is statistically significance between two groups. Present treatment modalities of SPMs are surgical operation, radiotherapy, chemotherapy and combination of these modalities. In choosing the treatment modality, we must consider the first treatment modality, region of primary disease, region of SPMs and general conditions of patient. Because development of SPMs have big effect on prognosis, prevention of SPMs must regard to important objective of treatments in patients of SCCa in oral cavity.

• Journal of Chest Surgery
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• 제20권4호
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• pp.673-682
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• 1987

The principal feature of bioprosthetic valve which remains to be completely defined is long-term durability, especially, with regard to the impact of patient age. This report provides extended data regarding valve durability derived from a data base of 515 patients who received lonescu-Shiley bioprosthetic valve between 1978 and 1985; cumulative duration of follow-up was 1562.3 patient-years, with a maximum follow-up duration of 8.7 years. The results of this survey showed as follows: 1] The actuarial freedom from valve failure at 6 years were 43*7% for 0-19 year-old group, 70*1% for 20-39 year-old group and 75*1% for over 40 year-old group separately. 2] Of the causes of valve failure, only the primary tissue failure was markedly influenced by patient`s age [p<0.001], but the prosthetic valve endocarditis was not [p>0.1]. 3] The linealized incidences of primary tissue failure were 7.31% per patient-year in 0-19 year-old group and 0.12% in 20-39 year-old group. 4] The primary tissue failure rate in 0-19 year-old group was 6.36% during first 4 years, but then increased upto 10.95% at postoperative 5 year. Thus we find that in bioprosthetic valve the primary tissue failure is apt to occur when patient is young [especially less than 20 years old] and the postreplacement time passes [especially over 5 years]. The rate of bioprosthesis failure among children and adolescents is clearly higher than that observed in adult patients; however, conclusive quantification of time-related risk for young patient is not yet possible on the basis of existing data. Therefore, the advisability of bioprosthesis implantation in children remains to be determined.

• Clinics in Shoulder and Elbow
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• 제8권2호
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• pp.88-96
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• 2005

Purpose: To compare and analyze the outcome of primary clavicular lateral end resection method and conventional acromioclavicular (AC) joint reduction method in type III AC dislocation patients over 45 years. Materials and Methods: This study was performed on selected 24 cases of type III AC dislocation patients, over 45 years of age, operated at our hospital from 1998 to 2002. Group I consist of 12 patients who underwent primary clavicular lateral end resection methods (average age: 54.3 years$(45{\sim}72)$). Group II consist of 7 patients using Bosworth methods and 5 patients using Phemister methods (average age: 54.4 years$(45{\sim}71)$). Clinical outcome was evaluated by Weaver and Dunn method. Radiological results were compared by measuring coracoclavicular distance between normal and injured side. Results: As clinical outcome, good was 10 cases(83%); fair 2(17%) in Group I, and good 6(50%); fair 3(25%); poor 3(25%) in Group II. In contrast, the difference of coracoclavicular distance was not statistically significant between two groups before or after surgery, and last follow up. At the last follow up, there was no special correlation between the difference of coracoclavicular distance and clinical outcome. Conclusion: We considered that primary clavicular lateral end resection may be effective for prevention of arthrosis in AC joint in type III AC dislocation patients over 45 years.

• Journal of Nutrition and Health
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• 제30권7호
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• pp.832-839
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• 1997

The purpose of this study is to survey the prevalence of obesity assessed on the basis of height and weight among students in primary and secondary schools in the metropolitan area of Seoul, Korea during the period of 1979 to 1996. The major findings are as follows ; 1) The fiftieth percentile values of BMI have increased more in mid-ranged age group than upper(16-17 years old) and lower(6-7 years old) ranged age groups. 2) The prevalence of obesity by standard weight of height was higher among male students than female students and students in the primary schools showed higher weight increase than adolescent age(12-17 years old) group. As a whole, the prevalence of obesity over last 18 years has increased 4.6 times in males and 3.2 times in females. 3) Judged on the basis of the BMI 90th, 95th percentile values of 1979 , the prevalence of obesity among male students showed higher increases than among female students. Higher increase was also observed among primary school students than among middle and high school students. Increase of weight was higher for the $\geq$95th percentile group than the 90-95th percentile group. 4) Judged on the basis of the BMI, 90th, 95 th percentile values of NHANES-I, the $\geq$95th percentile group showed higher increase in the prevalence of obesity than the 90-95th percentile group. According to the 1996 data, severe obesity group ($\geq$95th percentile) was about two times of NHANES-I in male primary school students, while the number for female middle and high school students was about 1/5 of NHANES-I.

• Journal of Nutrition and Health
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• 제35권1호
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• pp.69-77
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• 2002

The purpose of this study was to determine the probability of overweight throughout childhood in relation to the presence of overweight at birch or in early childhood, and presence of overweight in children's parents. Weight and height measures were collected at birth and at ages of 7, 10, 12 years from 655 6th grade primary schoolchildren. Childhood overweight was defined as a body mass index at or above the 85th percentile for age and sex, and overweight in children's parents as a body mass index at or above 27. The prevalence of overweight increased with age of the children. Overweight at birth was not associated with overweight at 12 years of ages. However, overweight at 12 years old was already related to overweight at 7 years old. In comparison to non-overweight peers, overweight children at ages 7(OR = 7.64, 95% CI = 4.32-13.51) and 10 years(OR = 19.69, 95% CI = 11.42-33.94) had a higher rick of becoming overweight at 12 years of age. Among children who was overweight at age 7years, 60.7% remained overweight 5 years later, Yearly increment in BMI of overweight children was larger than that of non-obese children (1.15-1.65kg/m$^2$vs 0.50-0.71kg/m$^2$. As compared with the lower case in mealy increment of BMI, the probability of being overweight at age of 12 years was greater in higher case. BMI values at age 7years were positively correlated with BMI values at age of 10 and 127ear,i, and with annual increments in BMI. But those relationships with birth weight were not observed. Children were at greater risk for overweight if at least ogle parent was overweight. The odds ratio for child overweight associated with maternal overweight was 2.41(95% CI = 1,13-5.IS), and those associated with paternal overweight 1.70(95% CI = 0.92-3.17). And parents' BMIs were positively correlated with children's BMI values and yearly BMI increment. In conclusion, overweight at early childhood and annual inclement in BMI can be important in predicting the prevalence of overweight and the risk that overweight will remain after 7 years of age. The risk of being overweight throughout the childhood increases by the parents'overweight.

• 대한핵의학회지
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• 제35권4호
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• pp.231-240
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• 2001

Purpose: Normal aging results in detectable changes in the brain structure and function. We evaluated the changes of regional cerebral glucose metabolism in the normal aging process with FDG PET. Materials and Methods: Brain PET images were obtained in 44 healthy volunteers (age range 20-69 'y'; M:F = 29:15) who had no history of neuropsychiatric disorders. On 6 representative transaxial images, ROIs were drawn in the cortical and subcortical areas. Regional FDG uptake was normalized using whole brain uptake to adjust for the injection dose and correct for nonspecific declines of glucose metabolism affecting all brain areas equally. Results: In the prefrontal, temporoparietal and primary sensorimotor cortex, the normalized FDG uptake (NFU) reached a peak in subjects in their 30s. The NFU in the prefrontal and primary sensorimotor cortex declined with age after 30s at a rate of 3.15%/decade and 1.93%/decade, respectively. However, the NFU in the temporoparietal cortex did not change significantly with age after 30s. The anterior (prefrontal) posterior (temporoparietal) gradient peaked in subjects in their 30s and declined with age thereafter at a rate of 2.35%/decade. The NFU in the caudate nucleus was decreased with age after 20s at a rate of 2.39%/decade. On the primary visual cortex, putamen, and thalamus, the NFU values did not change significantly throughout the ages covered. These patterns were not significantly different between right and left cerebral hemispheres. Of interest was that the NFU in the left cerebellar cortex was increased with age after 20s at a rate of 2.86%/decade. Conclusion: These data demonstrate regional variation of the age-related changes in the cerebral glucose metabolism, with the most prominent age-related decline of metabolism in the prefrontal cortex. The increase in the cerebellar metabolism with age might reflect a process of neuronal plasticity associated with aging.