• Title/Summary/Keyword: preventive drug

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Comparison about adverse drug reaction report forms among Asian's countries using herbal medicine (한약을 사용하는 아시아권 국가의 유해사례 보고 양식에 관한 비교 연구)

  • Sun, Seung-Ho;Lee, Eun-Kyoung;Jang, Bo-Hyoung;Park, Sunju;Go, Ho-Yeon;Jeon, Chan-Yong;Ko, Seong-Gyu
    • Journal of Society of Preventive Korean Medicine
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    • v.19 no.3
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    • pp.91-102
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    • 2015
  • Objective : The purpose of this study is to find out the possibility of application to herbal medicine's report form for adverse drug reaction (ADR) by reviewing and analyzing Asian countries's ADR report forms. Method : We investigated, compared, and analyzed ADR report forms (ADR-RF) of Asian countries's ADR institutions (ACAI), such as, Korea institute of drug safety & risk management and Dongguk university Ilsan oriental hospital (DUIOH) in Korea, national center for ADR monintoring (NCAM) in China, pharmaceuticals and medical devices agency (PMDA) in Japan, Ministry of Health and Welfare (MOHW) in Taiwan, and drug office, department of health, the government of the Hong Kong special administrative region (GHKSAR) in Hong Kong. Results : ADR-RF for ACAI included common contents, such as, patients information (name(initial), gender, age, weight), adverse event (AE)'s report information (Recognition and report for AE occurrence, first or follow up report, Severe AE), the detailed information of AE (the title of AE, onset & closing date of AE symptoms, the progress & results detailed test of AE), the information of AE's medicine (the types of medicine, product name, ingredient name, suspected or combination drug, single dose & frequency, dosage form, administration route, dealing for AE-suspected medicine), and AE reporter's information (reporter's information, institution's information). Taiwan had ADR-RF and the department exclusively for herbal medicine (HM), but others (except DUIOH) had not only no ADR report form but also contents for HM. Conclusion : ADR-RF for HM have to include the common contents of ACAI at least, as well as HM information related to ADR, such as the title, composition and types of HM, history related to HM's ADR, and the contents of drug-induced liver injury and so on. In addition, the main department of government for HM's ADR will be needed.

An Investigation on Acute Drug Intoxication (급성약물중독(急性藥物中毒)에 관(關)한 조사성적(調査成績))

  • Cho, Soo-Hun
    • Journal of Preventive Medicine and Public Health
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    • v.10 no.1
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    • pp.25-33
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    • 1977
  • The epidemiological informations on 1,828 cases of acute drug intoxication admmitted to the emergency rooms of 5 general hospitals, 4 in Seoul City and 1 in Incheon City from Jan. 1974 to Dec. 1974, were reviewed for statistical analysis. More detailed information on 796 cases from 3 hospitals were available in terms of the causative agent. The general findings obtained are as follows; 1. The sex ratio of the patient is 1.26 females to 1 male and this figure is almost consistent with the reports of previous authors. 49.7% of total cases were found in the age group of 20-29, which indicate the highest in percent distribution of age. 2. The incidence of acute drug intoxication was different by the season as the highest in summer and the lowest in winter. 3. As the cause of the intoxication, the attempted suicide occupied the single highest one with 91.7%. 4. The kind of causative agents varies with seasons as more economic poisons in the summer time and more drugs in the winter time.

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Demand Forecasting for Developing Drug Inventory Control Model in a University Hospital (한 종합병원 약품 재고관리를 위한 수요예측(需要豫測))

  • Sohn, Myong-Sei
    • Journal of Preventive Medicine and Public Health
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    • v.16 no.1
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    • pp.113-120
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    • 1983
  • The main objective of this case study is to develop demand forecasting model for durg inventory control in a university hospital. This study is based on the pertinent records during the period of January 1975 to August 1981 in the pharmacy and stock departments of the hospital. Through the analysis of the above records the author made some major findings as follows: 1. In A.B.C. classification, the biggest demand (A class) consists of 9 items which include 6 items of antibiotics. 2. Demand forecasting level of an index or discrepancy in A class drug compared with real demand for 6 months is average 30.4% by X-11 Arima method and 84.6% by Winter's method respectively. 3. After the correcting ty the number of bed, demand forecasting of drug compared with real demand for 6 months is average 23.1% by X-11 Arima method and 46.6% by Winter's method respectively.

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Effect of Lifestyle Modification Program on Blood Pressure Improvement in Patients with Hypertension (고혈압 환자에서 생활습관 개선 프로그램의 혈압개선효과)

  • Lee, Sang-Uk;Oh, Chang-Mo;Oh, In-Hwan;Yoon, Tai-Young;Choi, Joong-Myung
    • Korean Journal of Health Education and Promotion
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    • v.27 no.4
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    • pp.105-112
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    • 2010
  • Objectives: The purpose of this study was to know different effect with uncontrolled hypertension patients after providing health promotion program which consisted with medicine, exercise, nutrition. Methods: The subjects of this study was comprised by uncontrolled hypertension patients in spite of medication and didn't care the pressure by medication. The health promotion program was progressed by group exercise three times a week, nutrition education once a week and medical consultation once a month for 12 weeks. Subjects were measured for body composition(weight, fat mass, % body fat and body mass index), hemo-dynamics(systolic blood pressure(SBP), diastolic blood pressure(DBP), and resting heart rate), and physical fitness (cardiopulmonary endurance, muscular strength, muscular endurance, balance, and flexibility). Results: Groups showed significant improvement in every measure except resting heart rate. SBP is decreased both taking drug group about 18.4mmHg and without taking drug group about 19.4mmHg.(p<0.001) DBP is decreased both taking drug group about 8.7mmHg and without taking drug group about 9.0 mmHg.(p<0.001) Conclusion: There are no statistical significant differences of SBP and DBP decreasing effects by medication, Since effects of decreasing pressure are not different by medication, I think the health promotion program is effective to uncontrolled hypertension patients to decrease pressure.

Cost-benefit Analysis of Mandatory Prescription in Korea (의약분업의 비용-편익 분석)

  • Kim, Han-Joong;Park, Eun-Cheol;Kang, Hye-Young;Jee, Young-Keon
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.4
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    • pp.484-494
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    • 2000
  • Objective : To evaluate the relative benefits and the costs associated with the introduction of the new pharmaceutical provision called 'Mandatory Prescription System' which separates the role of physicians from that of pharmacists with respect to the prescription and dispensation of from the perspective of consumers (i.e., patients). Methods : The costs of the system were measured by considering both direct and indirect costs. Direct costs included additional payments for ambulatory care and dispensing fees that occurred under the new system. indirect costs consisted of transportation expenses and costs related to time spent for physician consultation, waiting for the prescriptions to be filled, and extra traveling. Benefits identified in this study were the reduction of drug misuse and overuse, and the overall decrease in drug consumption among the Korean population. Sensitivity analysis was peformed for the inclusion of benefits for outpatients of hospitals, price elasticity, and increased fees for established patients. Results : The net benefit was estimated to be about minus 1,862 billion won and the benefit-cost ratio was 0.478. This indicates that the costs of 'Mandatory Prescription' outweigh its benefits, relative to the previous system. The sensitivity analysis results for all the variables considered in this study consistently showed the benefit-cost ratio to be less than 1. Conclusion : The results of this study suggest that implementing Mandatory Prescription System in Korea might be inefficient from the consumer's perspective. The results of this study do not coincide with the results of previous studies, presumably because of the differences in study design and in which items of costs and benefits were considered.

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A Study on the Changes in Legal Definition of Medicinal Products in the Relevant Laws and Regulations (의약품 관련 법규상 개념 정의의 시행연혁에 관한 소고)

  • Eom, Seok-Ki
    • Journal of Society of Preventive Korean Medicine
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    • v.18 no.1
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    • pp.23-41
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    • 2014
  • Objective : The purpose of this study was to lay the groundwork for understanding the details and scope of the legal definition of medicinal products, following the changes in the relevant laws and regulations. This will let readers properly understand the origins of the ongoing conflicts on herbal drugs and new drugs from natural products that are present in the medical field and the medical industry. Possible solutions are proposed in the end. Method : I analyzed the changes in definition of medicinal products since 1945 that have been used in relevant laws and regulations(i.e. Pharmaceutical Affairs Act) and drug approval process(i.e. New Drug Application and Investigational New Drug Application). Results : Legal definition of medicinal products has changed in accordance with the changes in the pharmaceutical industry, such as the establishment of dualistic medical and pharmaceutical System and the introduction of the substance patent. Due to those changes, boundaries of Western medicinal products and health food expanded, while those of herbal medicine products relatively downscaled. Conclusion : Legal definition of medicinal products-i.e. Herbal Drugs, Crude Drugs, and New Drugs from Natural Products-should be reestablished according to academic legitimacy and dualistic medical and pharmaceutical System.

Effects of a Drug Misuse and Abuse Prevention Program on Knowledge, Attitude, and Preventive Behaviors Related to Drug Misuse and Abuse, and Depression in Low-income Elderly Women (약물 오$\cdot$남용 예방프로그램이 저소득 여성노인의 약물 오$\cdot$남용 예방에 대한 지식, 태도, 예방행위 및 우울에 미치는 효과)

  • Shin Kyung-Rim;Kim Jeong-Sun;Kim Jin-Young;Yi Hye-Ryeon
    • Journal of Korean Academy of Nursing
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    • v.35 no.5
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    • pp.763-773
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    • 2005
  • Purpose: This study was conducted to determine the effects of a drug misuse and abuse prevention program on knowledge, attitude, and preventive behaviorsrelated to drug misuse and abuse, and depression in low-income elderly women in the urban area. Method: The design of this study was a nonequivalent control group pretest-posttest design. The subjects consisted of 26 in the experimental group and 23 in the control group. The program was performed for about 1 hour, once a week for 5 weeks. Data was analyzed by the SAS(ver.8.02) computer program, and it included descriptive statistics, Fisher's exact test, Mann-Whitney U test, Wilcoxon signed ranks test, and ANCOVA. Result: There were statistically significant differences in knowledge, attitude, and preventive behaviors related to drug misuse and abuse, and depression between the experimental group and the control group. Conclusion: This study showed that this prevention program of drug misuse and abuse is appropriate for low-income elderly women, Therefore this program is recommended as a nursing intervention strategy for the elderly.