• Title/Summary/Keyword: preservation administration

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Anti-amnesic Effect and Antioxidant Defense Systems of Yukmijihwang-tang on Scopolamine-induced Memory Impairment in Mice (Scopolamine 유발 건망증 마우스 모델에서 육미지황탕(六味地黃湯)의 기억력 개선 및 항산화 효과)

  • Seo, Young-Min;Han, Da-young;Kim, Sang-ho;Chung, Dae-kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.29 no.4
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    • pp.207-221
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    • 2018
  • Objectives: The objective of this study was to observe the anti-amnesic effects of Yukmijihwang-tang (YMJHT), on the scopolamine (Sco)-induced memory impairment in C57BL/6 mice through its favorable acetylcholine (ACh). Also, to observe acetylcholinesterase (AChE) activity, Choline acetyltransferase (ChAT) mRNA expressions, and antioxidant effect. Methods: Six groups, with a total of 20 normal and 100 Sco treated mice were selected based on their body weights after 1 week of acclimatization, were used in this study as follows. Half of the mice in each group were used for passive avoidance task tests and hippocampus ACh content, AChE activity and ChAT mRNA expression measurement, and the remaining half in each group used for Morris water maze test and measurement of cerebral antioxidant defense system. Results: Amnesia due to AChE activations and destroyed cerebral cortex antioxidant defense systems were markedly and dose-dependently inhibited after 28 days of continuous oral pre-treatment with YMJHT 400, 200 and 100 mg/kg, respectively. The overall effects of YMJHT 400 mg/kg were similar to those of tacrine 10 mg/kg. Conclusions: Based on the results, it was established that oral administration of YMJHT favorably alleviates Sco-induced memory impairment, through preservation of ACh, mediated by up-regulation of ChAT mRNA expressions and related AChE inhibition and augmentation of cerebral antioxidant defense system, at least in a condition of this experiment. The overall effects of YMJHT 400 mg/kg were similar to those of tacrine 10 mg/kg.

Spatio-temporal Analysis of Forest Change using Spatial Information : A case study of Heongseong and Wonju (공간정보를 활용한 산림 변화 시공간분석: 횡성과 원주를 사례로)

  • Oh, Yi Kyun
    • Journal of Cadastre & Land InformatiX
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    • v.48 no.2
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    • pp.21-30
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    • 2018
  • The spatial information recently observed by various sensors and platforms has been provided by national portals through the establishment of a database over a number of time periods, with easy access to various types of information. Therefore, it is possible to analyze the changes in the national territory space according to time. This study is intend to analyze forest changes based on a case of some areas in Heongseong and Wonju using the various spatial information observed in many ways, such as aerial photographs, ortho photos, digital topographical maps, DEM and DSM. DSM created by the airborne lidar and the aerial photos was able to analyze forest change areas more effectively than DEM of topographical maps. Also, forest management and analysis could provide basic data for efficient preservation and management of forests using spatial information.

Tourists' Historical Image and Behavior Characteristics for Heritage Site at Wolseong Palace in Gyeongju (경주 월성의 역사공간 이미지 및 관광객 이용행태 분석)

  • Kang, Tai-Ho;Park, Joung-Koo;Pan, Xiang;Kim, Sang-Gu
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.29 no.4
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    • pp.148-158
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    • 2011
  • This study examines visitors' image and behavior characteristics of Wolseong palace in Gyeongju. This area has been a royal palace during Silla periods. So many scholars dedicate to the protection of this historical-cultural heritage. The research process consists of two main steps, such as on-site field investigation and survey research. The data were collected in summer and autumn. Collected data is classified into three groups to describe visitors' behavior, time, space, and then processed by statistical methods. The results are as follows: First, there is a shortage of programs and facilities. The result shows most visitors consider Wolseong palace as a pathway for walking. Hence better functions should be developed to attract more visitors but with least effect to historical remains. The founding is that increasing programs for history exploration, enhancing lighting installation, facilities, plant arrangement, road condition and so forth would be suggested.

Kureishi's The Buddha of Suburbia and the Issue of Re-ethnicization (쿠레이쉬의 『교외의 부처』와 "재인종화"문제)

  • Rhee, Suk Koo
    • Journal of English Language & Literature
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    • v.54 no.2
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    • pp.263-279
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    • 2008
  • Arif Dirlik in Postmodernity's Histories sees the issue of re-ethnicization in the case of John Huang, China's alleged attempt at lobbying the Clinton administration. In this view, Americans with Chinese surnames were suspected by the US Justice Department to be possible spies working for Beijing. Reethnicization here seems to serve the mainstream society in reducing an ethnic minority to a group of aliens operating for their countries of origin. However, re-ethnicization is not necessarily a one-way oppressive operation; it is often made use of by the ethnic minorities in their efforts to adapt to their country of arrival. Haroon and Karim, the protagonists of Hanif Kureishi's The Buddha of Suburbia, are cases in point. They are portrayed as winning social recognition and securing a place of their own within the hostile host society through a strategic use of re-ethnicization, that is, masquerading as 'genuine Orientals.' This study brings to light possible fallacies or misguided expectations concerning the political position of first- and second-generation immigrants. One of the fallacies is found in the racist metropolis, which regards the ethnic minorities as a sort of resident aliens, no matter what immigrant generation the latter belongs to. Another fallacy is found in the kind of postcolonial criticism that automatically regards an anti-racist critique advanced by people like Kureishi as something motivated by a confrontational tactic, that is, an attempt at subverting the colonial power relations. The conclusion of this study is that Kureishi's agenda, as presented in The Buddha of Suburbia, is neither the preservation of an ethnic identity nor the subversion of colonial power relations but survival in the metropolis. On this account Kureish's agenda can be called a micro-politics.

Preliminary Study on Effect of Lactiplantibacillus plantarum on Osteoporosis in the Ovariectomized Rat

  • Eun-Sun Jin;Ji Yeon Kim;JoongKee Min;Sang Ryong Jeon;Kyoung Hyo Choi;Shehzad Abid Khan;Gi-Seong Moon;Je Hoon Jeong
    • Food Science of Animal Resources
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    • v.43 no.4
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    • pp.712-720
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    • 2023
  • Osteoporosis is a growing global health concern primarily associated with decreased estrogen in postmenopausal women. Recently, some strains of probiotics were examined for potential anti-osteoporotic effects. This study intended to evaluate the impacts of Lactiplantibacillus plantarum MGE 3038 strain (MGE 3038) in ovariectomized rats. For this purpose, twelve weeks old female Wistar rats (n=21; 250-300 g) were divided into 3 groups; ovariectomy (OVX) group, OVX/MGE 3038 group and Sham group (control). In these groups; two went through respective OVX and one had daily MGE 3038 administration through oral gavage. Prior to 16 weeks after OVX, we collected blood samples and extracted the tibiae. We scanned the extracted tibiae by in-vivo micro-computed tomography (micro-CT) and evaluated pathology by hematoxylin and eosin (H&E) and Masson's trichrome staining. The serum levels of C-telopeptide of type I collagen (CTX), osteocalcin (OC), and the receptor activator of nuclear factor-κB ligand (RANKL) were examined. The OVX/MGE 3038 group showed increases in bone mineral density, trabecular bone volume, trabecular number, and trabecular thickness (Tb.Th), and a decrease in trabecular spacing than the OVX group. However, OVX/MGE 3038 group and control group were measurably comparable in Tb.Th. Micro-CT, H&E, and Masson's trichrome findings exhibited increased preservation and maintenance of trabecular bone structure in the OVX/MGE 3038 group in comparison to the OVX group. In serum, the levels of CTX, OC and RANKL were significantly different between the OVX and OVX/MGE 3038 groups. Taken together, L. plantarum MGE 3038 could be helpful for the treatment of osteoporosis.

Research about Application Possibility of Afforestation Reinforced Soil Steep Slope by Nonwoven Geotextile (부직포를 활용한 급경사 녹화보강토공법의 적용 가능성에 관한 연구)

  • Cho, Yong-Seong;Koo, Ho-Bon;Lee, Choon-Kil
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.4C
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    • pp.239-245
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    • 2006
  • The steep slopes have been increased of new roads, industrial site development and large scale residential development. The preservation administration and steep slope construction are currently investigated by many researchers in Korea. However, concrete retaining wall or reinforced soil (i.e. Block or Pannel) are being applied for the steep slope, which results in the front face form of the structure being limited. This research investigates the method that can make up afforestation environment-friendly circumstances during the construction of steep slope structure. It is considered that steep slope reinforced structure would be possible based on the monitoring results about earth pressure, horizontal displacement and consolidation quality generated during the construction of whole constructing reinforced structure. Also, there no problems in grassy surface, drainage, and deformation in spite of rainy season after construction period and until now. So that the seeding soil layer surface reinforced soil method could be adopt for steep slope reinforced structure and others.

Effect of hot-air drying temperature on nutritional components and rehydration rate of sweetpotato leaves (열풍건조 온도에 따른 고구마 잎의 영양성분 및 수화복원성 변화)

  • Jeong, Da-Woon;Park, Yang-Kyun;Nam, Sang-Sik;Han, Seon-Kyeong
    • Food Science and Preservation
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    • v.22 no.4
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    • pp.498-504
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    • 2015
  • The purpose of the present study is to provide preliminary data for turning sweetpotato leaves into dehydrated vegetables. To achieve this goal, we have gone through the process of hot-air drying the leaves of sweetpotato that are usually thrown away and examined the drying speed and rehydration resilience, then made a comparative analysis of the general ingredients, lutein, $\beta$-carotene and chromaticity. The drying speed reached the peak at a temperature of $70^{\circ}C$. As for other general ingredients, there was no significant difference according to temperature. The content of lutein, which is a functional ingredient, was large in Shinmi with $171.59{\mu}g/g$ at a temperature of $40^{\circ}C$; small in Hayanmi with $73.75{\mu}g/g$ at a temperature of $70^{\circ}C$. The content of $\beta$-carotene was large in Shinmi with $379.59{\mu}g/g$ at a temperature of $40^{\circ}C$; small in Hayanmi with $170.78{\mu}g/g$ at a temperature of $70^{\circ}C$. The content of functional materials was the largest at a temperature of $40^{\circ}C$, and decreased in the order of temperatures at $50^{\circ}C$, $60^{\circ}C$, and $70^{\circ}C$. As for rehydration stability, rehydration rate in both Shinmi and Hayanmi was the highest at a temperature of $40^{\circ}C$ with 233.93% and 223.47% respectively. To summarize, the quality of dried sweet potato leaf was more affected by temperature than by drying time, and low temperature drying resulted in better product value.

The Qualities of Northern and Southern Ecotype Garlic Bulbs at Different Storage Temperature (한지형' 및 '난지형' 마늘의 저장온도에 따른 품질 특성)

  • Bae, Ro-Na;Choi, Sun-Young;Hong, Yoon-Pyo
    • Food Science and Preservation
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    • v.15 no.5
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    • pp.635-641
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    • 2008
  • This study was conducted to investigate the optimal sub-zero temperature for storage of two garlic cultivars, the northern ecotype 'Jaerae' and the southern ecotype 'Daeseo'. These cultivars of garlic bulbs were stored at different temperature (room temperature, $0^{\circ}C$, and $-4^{\circ}C$) conditions after predrying. Southern ecotype garlic showed higher weight loss than northern ecotype garlic. Northern ecotype garlic at $-4^{\circ}C$ exhibited less than 5% of weight loss during 10 month storage. Sprouting rate was higher in southern than in northern ecotype at room temperature storage. The value of injury by disease and insect was similar between southern ecotype and northern ecotype for 5 month storage, and then northern ecotype showed higher value of injury by disease and insect than southern ecotype. Hunter 'b' value of northern ecotype garlic was the lowest at $-4^{\circ}C$ storage. Northern ecotype garlic showed no cold injury at freezing point temperature storage. However, southern ecotype garlic had $0{\sim}5.3%$ cold injury occurrence at $-4^{\circ}C$ storage. Respiration and ethylene production exhibited the highest at room temperature storage, those had the slight increase at $0^{\circ}C$ and $-4^{\circ}C$ storages. Northern ecotype showed higher enzymatic pyruvic acid and fructan contents than those of southern ecotype. Enzymatic pyruvic acid content increased and fructan contents decreased during storage time.

Effect of Leuconostoc kimchii GJ2 Isolated from Kimchi (Fermented Korean Cabbage) on Lipid Metabolism in High Cholesterol-Fed Rats (김치로부터 분리한 유산균 Leuconostoc kimchii GJ2가 고콜레스테롤식이를 급여한 흰쥐의 지질대사에 미치는 영향)

  • Lee, Jae-Joon;Lee, Yu-Mi;Kim, Ah-Ra;Chang, Hae-Choon;Lee, Myung-Yul
    • Food Science and Preservation
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    • v.15 no.5
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    • pp.760-768
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    • 2008
  • The present study investigated the effect of Leuconostoc kimchii GJ2 (Leu. kimchii GJ2), an exopolysaccharide-producing lactic acid bacterium isolated from kimchi, on serum and liver lipid metabolism in rats fed a high-cholesterol diet. Male Sprague-Dawley rats were divided into four groups: a normal diet group (ND), a high-cholesterol diet group (HCD), a high-cholesterol diet and 200 mg/kg Leu. kimchii GJ2-administered group (HCD-LKL), and a high-cholesterol diet and 400 mg/kg Leu. kimchii GJ2-administered group (HCD-LKH). No between-group differences were found in body weight gain, food intake, or food efficiency ratio. The serum GOT and ALP activities that were elevated by the high-cholesterol diet were significantly decreased after Leu. kimchii GJ2 administration. Serum HDL-cholesterol level was markedly increased in the Leu. kimchii GJ2-administered groups, whereas the serum total cholesterol and LDL-cholesterol levels were lower in the Leu. kimchii GJ2-administered animals. Liver levels of total cholesterol and triglyceride were also markedly lower in the Leu. kimchii GJ2-administered groups. In addition, increased activities of HR-LPL and TE-LPL in adipose tissue, caused by the high-cholesterol diet, fell to normal after administration of Leu. kimchii GJ2, in a dose-dependant manner. These results suggest that Leu. kimchii GJ2 isolated from kimchi exerts an antiatherosclerotic effect by reducing serum and liver cholesterol levels.

Effects of Vitamin C on Residual Aflatoxin $B_1$ in Rat Sera Treated with Radiation and Aflatoxin $B_1$ (Vitamin C가 방사선과 Aflatoxin $B_1$을 투여한 흰쥐의 혈청 중 Aflatoxin $B_1$ 잔류량에 미치는 영향)

  • Chung, Do-Young;Kim, Han-Soo;Kang, Jin-Soon
    • Food Science and Preservation
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    • v.18 no.3
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    • pp.374-382
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    • 2011
  • Aflatoxin ($AFB_1$) is a potent hepatotoxic and hepatocarcinogenic mycotoxin in humans. It is also well-known to be accumulated in animal tissues via various metabolic pathways. This study was conducted to determine the effects of vitamin C on the residual $AFB_1$ in rat sera that were treated with radiation and $AFB_1$. Six week-old male Sprague-Dawley rats were randomly divided into five groups: a control group, $AFB_1$-treated group, the group treated with $AFB_1$ and vitamin C, the group treated with X-ray and AFB1, and the group treated with X-ray and $AFB_1$ with vitamin C. On the first day of the experiment, only one dose of X-rays was exposed to the entire liver at 1,500 cGy. Next, vitamin C was injected at 10 mg/kg body weight via intraperitoneal injection, followed 1 hr later by the administration of 0.4 mg/kg of $AFB_1$ via intraperitoneal injection. These treatments were then administered every three days over a period of 15 days. On the 16th day of treatments, the animals were sacrificed. The contents of $AFB_1$ in rat sera were determined via indirect competitive ELISA and HPLC method. In the quantitative analysis of $AFB_1$ in rat sera via ELISA, $5.17{\pm}0.34$ ng/mL of $AFB_1$ was detected in the $AFB_1$-treated groups, but the amount more significantly decreased to $3.23{\pm}0.76$ ng/mL in the groups treated with $AFB_1$ and vitamin C (p<0.01) than in the $AFB_1$-treated groups. The $AFB_1$ contents of the rat sera of the groups treated with X-ray and $AFB_1$ did not significantly decreased with the administration of vitamin C. The $AFB_1$ content of the rat sera that was analyzed via HPLC showed a tendency similar to that of the content that was analyzed via ELISA. With regard to these data, vitamin C was very effective in reducing $AFB_1$ residue in rat sera.