• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2004년도 Annual Meeting of KSAP : New Drug Development from Natural Products
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• pp.61-77
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• 2004

Present review is built on base of research work on Ganoderma lucidum in our laboratory. A great deal of experimental evidence has suggested that the pharmacological activities of Ganoderma lucidum(Lingzhi) are related to anti-oxidative and free radical scavenging activity. The anti-oxidative and free radical scavenging effects of polysaccharides and triterpenoids isolated from Ganoderma lucidum in different oxidative injury models including tert-butylhydroperoxide (tBOOH)- damaged mice peritoneal macrophages, alloxan-induced diabetes, experimental liver injury models induced by carbon tetrachloride (CC14), D-galactosamine (DGal) and Bacillus Calmette-Guerin(BCG) plus lipopolysaccharides(LPS) were investigated. It is also demonstrated that Lugu lingzhi, one of Ganoderma product, significantly inhibited LDL oxidation mediated by endothelial cells and decreased monocyte adhesion to endothelial cell (EC) induced by Oxidative low-density lipoprotein (ox-LDL) and advanced glycation endproducts(AGE). Lugulingzhi-treated serum could markedly inhibit the expression of intercellular cell adhesion molecule-l (ICAM-1) and vascular cell adhesion molecule-l (VCAM-1) induced by ox-LDL and AGE.

• Journal of Chest Surgery
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• 제22권6호
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• pp.990-995
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• 1989

Since 1984, 24 patients underwent repair of atrioventricular septal defect. Nineteen had a partial defect and 5 had a complete atrioventricular septal defect. There were 9 men and 15 women, ranging in age from 1 to 50 years [mean age, 13.3 years]. Four patients had a Downs syndrome. Additional congenital heart defects were present in 11 patients. One patient had palliative operation prior to total correction. In partial defects, the primum atrial septal defect was closed with Xenomedica patch and the mitral valve was repaired with simple closure of the septal commissure. Central incompetence from annular dilatation was repaired by a local annuloplasty. In complete defect, the septal defects were closed with two patches except one. Operative mortality was 5% in partial defects and 60% in complete defects and low cardiac output was the commonest etiology. In a mean follow-up period of 27.9 months [range, 4 to 63 months] there were no late death and no instances of late-onset complete heart block. One patient required reoperation [MVR] for residual mitral regurgitation. The majority of patients were asymptomatic and mean postop. NYHA functional class was 1.2.

• Journal of Chest Surgery
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• 제21권1호
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• pp.164-168
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• 1988

Between November, 1984, and May, 1986, 93 patients underwent combined valvular and coronary artery operation. They were 70 male and 23 female, the age ranging from 29 to 82. From this population 89 patients underwent single valve replacement and 4 patients underwent double valve replacement. Patients with mitral valve disease were in the majority present in the age group between 50 till 70, where as in the group after 60 years, patients with aortic valve disease were dominant. The main indication for aortic valve replacement was aortic stenosis and the indication for mitral valve replacement was equal between mitral stenosis and mitral incompetence, the later was due to papillary dysfunction after myocardial infarction. Dyspnea was a very frequent symptom and it was found in nearly all patients. 28 patients had a previous myocardial infarction and severe left ventricular dysfunction. The grafts were placed prior to valve replacement and periods of myocardial ischemia were kept at a minimum by maintaining coronary perfusion throughout the operation. It is our opinion that simultaneous valve replacement and myocardial revascularization does not increase the risk of cardiac valve replacement substantially.

• 대한두경부종양학회지
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• 제14권2호
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• pp.260-262
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• 1998

Metastatic squamous carcinoma of the head and neck may rarely present as a cyst in the cervical region. The true incidence of metastatic cystic neck mass is unknown. It is difficult to differentiate metastatic cystic neck mass from congenital cystic neck mass with physical examination and fine needle aspiration biopsy. So the differential diagnosis is dependent on the age of the patient, and therefore in the patient over the 40 years of age, the possibility of a metastatic neck mass should be considered. We report a metastatic cystic neck mass which had been misdiagnosed as a branchial cleft cyst.

• 천문학회지
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• 제29권2호
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• pp.269-278
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• 1996

We present the color-magnitude diagrams (CMD) of more than 24,000 stars in the field of an intermediate age open cluster M11, based on wide field CCD imaging. The morphology of the CMDs varies strikingly as the distance from the center of the cluster increases. From the surface number density analysis, we confirm the mass segregation effect in this cluster: the bright, massive stars are centrally more concetrated than the faint, low mass stars. The slope of the field-corrected surface density with respect to magnitude progressively increases as the radius increases, up to r = 5'. Most of the field stars in or near the cluster main sequence band and in the bright part of the red stars in the CMDs appear to be nearly at the same distance as M11, and they are considered to be the major component of disk stars in the Sagittarius-Carina arm.

• Asian review of World Histories
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• 제1권1호
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• pp.85-116
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• 2013

The theory of terrestrial impact which has been developed by the astronomy scientists since 1970s is employed for this article in a new angle that atmospheric conditions of our planet should be adopted in the interpretation of the history of mankind. Large and small terrestrial impacts must be acknowledged as key tasks in terms of the study of 'world history'. The Society of Interdisciplinary Studies has already advocated that the 'Bronze Age Civilization' was strongly influenced by the long term terrestrial impact phenomena. Based on historical materials from Korea, the present study was able to identify the years 680-880, 1100-1220, 1340-1420, and 1490-1760 as periods in which territorial impacts occurred.

• 설비공학논문집
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• 제27권2호
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• pp.57-62
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• 2015

The objective of the present study is to identify the ventilation problems and to suggest the optimal ventilation system to save energy and to improve IAQ in the computer rooms, which annually performs the cooling operation by the server with the highly thermal load. Numerical results on the temperature and local mean age are presented along with some of the discharge velocities. Results show many interesting aspects of airflow patterns affecting the ventilation performances, according to the discharge velocity of the supply diffuser installed in the bottom surfaces between the servers. As the results, 2.5 m/s of the optimal discharge velocity is needed in order to improve the ventilation performance.

• 설비공학논문집
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• 제26권5호
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• pp.206-211
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• 2014

The objective of the present study was to identify ventilation problems, and also to suggest new axial fan systems for the improvement of IAQ in the underground parking lots. Numerical results for air mean-velocity, local mean age, and sound power level are presented along with some of fan angles. The results showed the influence of airflow patterns on the fan performances installed in the underground parking lots. Discharge air volume is increased with the angle of the blade. And also, the main factors affecting the noise of the ventilation fan was found to be a rotational speed.

• 천문학논총
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• 제14권2호
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• pp.61-67
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• 1999

We present a new UBVI CCD photometry of the intermediate-age open cluster NGC 2420. Our photometry covers a field of $7'9\times7.'7$ of the sky centered on the cluster. We determined the reddening and distance to the cluster by the main sequence fitting as $E(B - V) = 0.05\pm0.02$ and $(m-M)_o = 11.9\pm0.1$, along with the age of $\~2$ Gyr by fitting the Padova isochrones to the observed color-magnitude diagrams of the cluster. The fraction of binaries is found to be $44\pm5\%$ and they are likely to locate in the central region of the cluster. The spatial distributions of the binaries and the variation of the cluster luminosity functions along the radius suggest mass segregations due to the dynamical evolution of the cluster.

• 한국전문물리치료학회지
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• 제8권2호
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• pp.87-94
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• 2001

Dexterity is defined in the present study as interdigital manipulative skill or the fine manipulative movements of objects held between the thumb and fingers. The Grooved pegboard test has been used to evaluate dexterity requring visual-motor coordination. The purpose of this study was to standardize the completion time of the Grooved pegboard test in different age groups and gender. Normative values for the Grooved Pegboard Test was developed on the sample of 282 healthy volunteers (89 men and 183 women). Subjects were stratified according to gender and dominant hand and were subdivided into six groups by blocking. The results of this study were as follows: 1) There was a significant difference in completion time between dominant and nondominant hand in both men and women groups (p<.05). 2) There were significant differences in completion time between men and women group (p<.05) 3) There were significant differences in completion time among age groups (p<.05).